Ggt1 (gamma-glutamyltransferase 1) - Rat Genome Database

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Gene: Ggt1 (gamma-glutamyltransferase 1) Rattus norvegicus
Analyze
Symbol: Ggt1
Name: gamma-glutamyltransferase 1
RGD ID: 2683
Description: Enables aminoacyltransferase activity. Involved in several processes, including liver development; response to estradiol; and response to tumor necrosis factor. Located in extracellular space. Biomarker of aflatoxins-related hepatocellular carcinoma and alcohol dependence. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Orthologous to several human genes including GGT1 (gamma-glutamyltransferase 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (R)-lipoic acid; (S)-nicotine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gamma glutamyl-transferase 1; gamma-glutamyl transpeptidase; gamma-glutamyltransferase; gamma-glutamyltranspeptidase; gamma-glutamyltranspeptidase 1; GGLUT; Ggt; GGT 1; Ggtp; glutathione hydrolase 1; glutathione hydrolase 1 proenzyme; leukotriene-C4 hydrolase; RATGGLUT
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82013,074,141 - 13,103,551 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2013,074,141 - 13,088,050 (-)EnsemblGRCr8
mRatBN7.22013,074,695 - 13,104,095 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2013,074,700 - 13,108,442 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2013,781,279 - 13,802,241 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02013,142,223 - 13,163,185 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,614,726 - 13,635,690 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02014,019,723 - 14,045,781 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2014,019,723 - 14,025,068 (-)Ensemblrn6Rnor6.0
Rnor_5.02016,209,337 - 16,231,303 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera2014,560,916 - 14,581,414 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(R)-lipoic acid  (EXP)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP)
1,2-dibromoethane  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (EXP)
2-amino-6-diazo-5-oxohexanoic acid  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
7,12-dimethyltetraphene  (EXP)
acetamide  (EXP)
Acetaminophen cystein  (ISO)
acetylsalicylic acid  (EXP)
acivicin  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
afzelechin  (EXP)
Alisol A  (EXP)
Alisol B  (EXP)
Alisol C 23-acetate  (EXP)
all-trans-retinoic acid  (EXP,ISO)
anethole  (EXP)
anilines  (EXP)
antimonite  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP)
asbestos  (ISO)
atazanavir sulfate  (ISO)
atrazine  (EXP)
Augmentin  (ISO)
barium chloride  (EXP)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
boric acids  (EXP)
brequinar  (ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chlordecone  (ISO)
Chlorobenzilate  (EXP)
chloroprene  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
coenzyme Q10  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
crotonaldehyde  (EXP)
CU-O LINKAGE  (EXP)
curcumin  (EXP)
cyclosporin A  (EXP,ISO)
DDT  (EXP)
deoxycholic acid  (ISO)
desloratadine  (EXP)
Di-n-octyl phthalate  (ISO)
diarsenic trioxide  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP)
dicofol  (EXP)
diethyl phthalate  (ISO)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (EXP,ISO)
endosulfan  (EXP)
entinostat  (ISO)
Epomediol  (EXP)
estradiol  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (EXP)
fenarimol  (EXP)
fenvalerate  (EXP)
fipronil  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (EXP)
gamma-hexachlorocyclohexane  (EXP,ISO)
genistein  (ISO)
glutathione  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhetinate  (EXP)
glycyrrhetinic acid  (EXP)
graphite  (EXP)
GW 4064  (ISO)
hexadecanoic acid  (ISO)
indole-3-methanol  (EXP)
irinotecan  (ISO)
isoniazide  (EXP)
L-ascorbic acid  (EXP)
lead oxide  (EXP)
lead(0)  (EXP)
letrozole  (EXP)
lipoic acid  (EXP)
lipopolysaccharide  (EXP)
manganese atom  (EXP)
manganese(0)  (EXP)
melatonin  (EXP)
menadione  (EXP)
mercury atom  (EXP,ISO)
mercury dichloride  (EXP)
mercury(0)  (EXP,ISO)
methotrexate  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
montelukast  (EXP)
N(5)-ethyl-L-glutamine  (EXP)
N-acetyl-L-cysteine  (EXP)
N-ethyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (EXP)
nefazodone  (ISO)
nickel atom  (EXP)
nickel sulfate  (EXP)
nicotine  (EXP)
nicotinic acid  (EXP)
nitrobenzenes  (EXP)
nitrogen dioxide  (EXP)
novobiocin  (ISO)
ochratoxin A  (EXP)
oleic acid  (ISO)
omeprazole  (EXP)
orphenadrine  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenobarbital  (EXP)
phentolamine  (ISO)
phenylephrine  (ISO)
PhIP  (EXP)
piperonyl butoxide  (EXP)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
prochloraz  (EXP)
quercetin  (ISO)
resveratrol  (EXP)
risperidone  (EXP)
S-hexylglutathione  (ISO)
sanguinarine  (ISO)
SB 203580  (EXP)
SB 431542  (ISO)
selenium atom  (EXP,ISO)
silicon dioxide  (ISO)
sirolimus  (EXP)
sodium acetate trihydrate  (EXP)
sodium arsenite  (ISO)
spironolactone  (EXP)
streptozocin  (EXP,ISO)
succimer  (ISO)
tamibarotene  (ISO)
Tanshinone I  (ISO)
telmisartan  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thymoquinone  (EXP,ISO)
topotecan  (EXP)
trans-anethole  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP,ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vitamin E  (EXP,ISO)
zinc atom  (EXP)
zinc oxide  (EXP)
zinc(0)  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
extracellular space  (IDA)
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO,ISS)
vesicle  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Characteristics of adults with and without cystic fibrosis-related diabetes. Adler AI, etal., Diabet Med. 2007 Oct;24(10):1143-8.
2. Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro. Aly HA, etal., Chem Biol Interact. 2009 Dec 10;182(2-3):112-8. Epub 2009 Aug 21.
3. Expression of rat renal gamma-glutamyltransferase cDNA in Escherichia coli. Angele C, etal., Biochem Biophys Res Commun. 1989 May 15;160(3):1040-6.
4. Diabetic complications are associated with liver enzyme activities in people with type 1 diabetes. Arkkila PE, etal., Diabetes Res Clin Pract. 2001 May;52(2):113-8.
5. Enhanced gamma-glutamyl transpeptidase expression and selective loss of CuZn superoxide dismutase in hepatic iron overload. Brown KE, etal., Free Radic Biol Med. 1998 Mar 1;24(4):545-55. doi: 10.1016/s0891-5849(97)00284-0.
6. Tissue-specific expression of two gamma-glutamyl transpeptidase mRNAs with alternative 5' ends encoded by a single copy gene in the rat. Chobert MN, etal., J Biol Chem 1990 Feb 5;265(4):2352-7.
7. The relation between liver histopathology and GGT levels in viral hepatitis: more important in hepatitis B. Eminler AT, etal., Turk J Gastroenterol. 2014 Aug;25(4):411-5. doi: 10.5152/tjg.2014.3693.
8. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Risk factors for incident type 2 diabetes in individuals with a BMI of <27 kg/m(2): the role of gamma-glutamyltransferase. Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR). Gautier A, etal., Diabetologia. 2009 Nov 20.
10. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
11. The Serum Gamma Glutamyl Transpeptidase - A Non invasive Diagnostic Bio Marker of Chronic Anicteric Non Alcoholic Liver Diseases. H A K, J Clin Diagn Res. 2013 Apr;7(4):691-4. doi: 10.7860/JCDR/2013/5569.2883. Epub 2013 Mar 9.
12. Protective effect of 17beta-estradiol on oxidative stress and liver dysfunction in aged male rats. Hamden K, etal., J Physiol Biochem. 2007 Sep;63(3):195-201.
13. Hyperglycaemia, stress oxidant, liver dysfunction and histological changes in diabetic male rat pancreas and liver: protective effect of 17 beta-estradiol. Hamden K, etal., Steroids. 2008 May;73(5):495-501. Epub 2008 Jan 4.
14. [The value of gamma-glutamyl transpeptidase mRNA typing in monitoring carcinogensis of heptocytes]. Han G, etal., Zhonghua Nei Ke Za Zhi. 2002 Mar;41(3):160-2.
15. Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels. Haring R, etal., Hepatology. 2009 Nov;50(5):1403-11. doi: 10.1002/hep.23135.
16. Differential expression of the rat gamma-glutamyl transpeptidase gene promoters along with differentiation of hepatoblasts into biliary or hepatocytic lineage. Holic N, etal., Am J Pathol. 2000 Aug;157(2):537-48. doi: 10.1016/s0002-9440(10)64564-6.
17. Clinical, virologic and pathologic significance of elevated serum gamma-glutamyl transpeptidase in patients with chronic hepatitis C. Hwang SJ, etal., Zhonghua Yi Xue Za Zhi (Taipei). 2000 Jul;63(7):527-35.
18. Correlation between gamma-glutamyl transpeptidase activity and outcomes after Kasai portoenterostomy for biliary atresia. Ihn K, etal., J Pediatr Surg. 2018 Mar;53(3):461-467. doi: 10.1016/j.jpedsurg.2017.10.001. Epub 2017 Oct 6.
19. Significance of serum gamma glutamyl transpeptidase as a marker of alcoholism. Ishii H, etal., Pharmacol Biochem Behav. 1980;13 Suppl 1:95-9. doi: 10.1016/s0091-3057(80)80015-3.
20. Gamma-glutamyl transpeptidase in leprosy. Jain VK, etal., Indian J Lepr. 1991 Jan-Mar;63(1):93-6.
21. Gamma-glutamyl transpeptidase level associated with metabolic syndrome and proinflammatory parameters in the young Roma population in eastern Slovakia: a population-based study. Jarcuska P, etal., Cent Eur J Public Health. 2014 Mar;22 Suppl:S43-50. doi: 10.21101/cejph.a3901.
22. Induced hepatotoxicity in female rats by aflatoxin B1 and ethynylestradiol interaction. Kamdem L, etal., Toxicol Appl Pharmacol. 1983 Jan;67(1):26-40. doi: 10.1016/0041-008x(83)90241-7.
23. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
24. Molecular cloning and nucleotide sequence of rat kidney gamma-glutamyl transpeptidase cDNA. Laperche Y, etal., Proc Natl Acad Sci U S A 1986 Feb;83(4):937-41.
25. [Serum gamma-glutamyl transpeptidase activity in children with chronic hepatitis B]. Lebensztejn DM, etal., Pol Merkur Lekarski. 2005 Mar;18(105):271-4.
26. Serum gamma-glutamyltransferase was differently associated with microalbuminuria by status of hypertension or diabetes: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Lee DH, etal., Clin Chem. 2005 Jul;51(7):1185-91. Epub 2005 May 12.
27. Serum gamma-glutamyltransferase predicts non-fatal myocardial infarction and fatal coronary heart disease among 28,838 middle-aged men and women. Lee DH, etal., Eur Heart J. 2006 Sep;27(18):2170-6. Epub 2006 Jun 13.
28. Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study. Lee DS, etal., Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):127-33. Epub 2006 Nov 9.
29. Nonlinear free energy relationship in the general-acid-catalyzed acylation of rat kidney gamma-glutamyl transpeptidase by a series of gamma-glutamyl anilide substrate analogues. Menard A, etal., Biochemistry 2001 Oct 23;40(42):12678-85.
30. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
31. The expression of gamma-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress. Mikkelsen IM, etal., Mol Cell Biochem. 2002 Mar;232(1-2):87-95.
32. Elevated gamma-glutamyl transpeptidase levels in malignant melanoma. Murray JL, etal., Cancer. 1982 Apr 1;49(7):1439-43. doi: 10.1002/1097-0142(19820401)49:7<1439::aid-cncr2820490721>3.0.co;2-1.
33. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
34. Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells. Pandur S, etal., Free Radic Res. 2007 Dec;41(12):1376-84.
35. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
36. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
37. Cloning and analysis of the rat gamma-glutamyltransferase gene. Rajagopalan S, etal., J Biol Chem 1990 Jul 15;265(20):11721-5.
38. GOA pipeline RGD automated data pipeline
39. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
40. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
41. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
42. Gamma-glutamyltransferase level in pregnancy is an independent risk factor for gestational diabetes mellitus. Tan PC, etal., J Obstet Gynaecol Res. 2008 Aug;34(4):512-7.
43. Prognostic value of alkaline phosphatase, gamma-glutamyl transpeptidase and lactate dehydrogenase in hepatocellular carcinoma patients treated with liver resection. Wu SJ, etal., Int J Surg. 2016 Dec;36(Pt A):143-151. doi: 10.1016/j.ijsu.2016.10.033. Epub 2016 Oct 25.
44. [Relationship between methylation status of gamma-glutamyl transpeptidase (GGT) genes and abnormal expression of its enzyme proteins in tissues of human hepatomas]. Yao D, etal., Zhonghua Gan Zang Bing Za Zhi. 1999 Sep;7(3):132-4.
45. Gamma glutamyl transpeptidase is a dynamic indicator of endothelial response to stroke. Yu C, etal., Exp Neurol. 2007 Jan;203(1):116-22. Epub 2006 Sep 14.
Additional References at PubMed
PMID:8776   PMID:1671556   PMID:2567622   PMID:2573604   PMID:2869471   PMID:2896486   PMID:2907498   PMID:6136502   PMID:6142889   PMID:7910821   PMID:9139708   PMID:12468440  
PMID:14754911   PMID:16386375   PMID:16502470   PMID:17582939   PMID:17924658   PMID:19419996   PMID:20458337   PMID:20622017   PMID:21447318   PMID:22984412   PMID:23376485   PMID:23533145  
PMID:23682772   PMID:23863468   PMID:24047895   PMID:27525410  


Genomics

Comparative Map Data
Ggt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82013,074,141 - 13,103,551 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2013,074,141 - 13,088,050 (-)EnsemblGRCr8
mRatBN7.22013,074,695 - 13,104,095 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2013,074,700 - 13,108,442 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2013,781,279 - 13,802,241 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02013,142,223 - 13,163,185 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,614,726 - 13,635,690 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02014,019,723 - 14,045,781 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2014,019,723 - 14,025,068 (-)Ensemblrn6Rnor6.0
Rnor_5.02016,209,337 - 16,231,303 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera2014,560,916 - 14,581,414 (-)NCBICelera
Cytogenetic Map20p12NCBI
GGT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,583,750 - 24,628,996 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,594,684 - 24,629,011 (+)Ensemblhg38GRCh38
GRCh372224,979,718 - 25,024,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,309,718 - 23,354,972 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342223,304,271 - 23,349,489NCBI
Celera228,779,459 - 8,824,717 (+)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef227,929,404 - 7,974,708 (+)NCBIHuRef
CHM1_12224,938,527 - 24,983,991 (+)NCBICHM1_1
T2T-CHM13v2.02225,045,351 - 25,090,447 (+)NCBIT2T-CHM13v2.0
Ggt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,396,910 - 75,422,027 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1075,397,438 - 75,422,034 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381075,561,076 - 75,586,193 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,561,604 - 75,586,200 (+)Ensemblmm10GRCm38
MGSCv371075,036,338 - 75,048,927 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361075,017,309 - 75,029,898 (+)NCBIMGSCv36mm8
Celera1076,618,288 - 76,630,876 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.55NCBI
Ggt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554558,068,710 - 8,099,584 (+)Ensembl
ChiLan1.0NW_0049554558,082,578 - 8,099,523 (+)NCBIChiLan1.0ChiLan1.0
GGT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22334,377,966 - 34,418,498 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12237,108,395 - 37,149,276 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0225,424,334 - 5,469,705 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GGT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12628,301,455 - 28,315,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2627,360,247 - 27,389,912 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02629,689,666 - 29,719,314 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2629,692,972 - 29,719,310 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12627,773,590 - 27,803,271 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02627,390,370 - 27,420,073 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02628,380,459 - 28,410,164 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ggt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118141,962,444 - 141,979,185 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936619762,102 - 791,631 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936619762,278 - 791,610 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103223058
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1197,353,922 - 7,406,392 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236661001,521 - 6,868 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ggt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474710,030,034 - 10,048,554 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ggt1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11811,858,956 - 11,869,227 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ggt1
140 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:118
Count of miRNA genes:91
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000074533
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804392029865039Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804392015089182Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
D20Arb3  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera2014,573,002 - 14,573,152UniSTS
FHH x ACI Map206.9298UniSTS
FHH x ACI Map206.9298RGD
Cytogenetic Map20 RGD
D20Arb4  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera2014,573,014 - 14,573,231UniSTS
RH 2.0 Map20189.0RGD
FHH x ACI Map206.8999RGD
Cytogenetic Map20 RGD
D20Wox9  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22013,092,820 - 13,093,043 (+)MAPPERmRatBN7.2
Rnor_6.02014,038,923 - 14,039,145NCBIRnor6.0
Rnor_5.02016,228,149 - 16,228,371UniSTSRnor5.0
Celera2014,578,646 - 14,578,868UniSTS
338D4-Sp6  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera2014,567,588 - 14,567,864UniSTS
Ggt1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera2014,561,656 - 14,562,583UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 65 152 91 90 59 92 59 6 353 189 11 131 81 92 31 14 14

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001434562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC078768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J05515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L29167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M33821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M33822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M57672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U17096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U17392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X15443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X52667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X52808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000074533   ⟹   ENSRNOP00000065923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2013,074,141 - 13,088,050 (-)Ensembl
mRatBN7.2 Ensembl2013,074,700 - 13,108,442 (-)Ensembl
Rnor_6.0 Ensembl2014,019,861 - 14,025,068 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093430   ⟹   ENSRNOP00000076324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2014,020,917 - 14,025,067 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093521   ⟹   ENSRNOP00000076317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2014,019,723 - 14,020,007 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137128   ⟹   ENSRNOP00000112639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2013,074,141 - 13,088,050 (-)Ensembl
RefSeq Acc Id: NM_053840   ⟹   NP_446292
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,095,104 (-)NCBI
mRatBN7.22013,074,700 - 13,095,664 (-)NCBI
Rnor_6.02014,019,723 - 14,045,781 (-)NCBI
Rnor_5.02016,209,337 - 16,231,303 (-)NCBI
Celera2014,560,916 - 14,581,414 (-)RGD
Sequence:
RefSeq Acc Id: XM_039098382   ⟹   XP_038954310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,091,767 (-)NCBI
mRatBN7.22013,074,695 - 13,091,994 (-)NCBI
RefSeq Acc Id: XM_039098383   ⟹   XP_038954311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,098,174 (-)NCBI
mRatBN7.22013,074,695 - 13,098,726 (-)NCBI
RefSeq Acc Id: XM_039098384   ⟹   XP_038954312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,088,329 (-)NCBI
mRatBN7.22013,074,695 - 13,088,613 (-)NCBI
RefSeq Acc Id: XM_039098385   ⟹   XP_038954313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,103,551 (-)NCBI
mRatBN7.22013,074,695 - 13,104,095 (-)NCBI
RefSeq Acc Id: XM_063278931   ⟹   XP_063135001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,095,859 (-)NCBI
RefSeq Acc Id: XM_063278932   ⟹   XP_063135002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,095,686 (-)NCBI
RefSeq Acc Id: XM_063278933   ⟹   XP_063135003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,103,551 (-)NCBI
RefSeq Acc Id: XM_063278934   ⟹   XP_063135004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,095,846 (-)NCBI
RefSeq Acc Id: XM_063278935   ⟹   XP_063135005
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,074,141 - 13,095,609 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001421491 (Get FASTA)   NCBI Sequence Viewer  
  NP_001421492 (Get FASTA)   NCBI Sequence Viewer  
  NP_001421493 (Get FASTA)   NCBI Sequence Viewer  
  NP_001421494 (Get FASTA)   NCBI Sequence Viewer  
  NP_446292 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954310 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954311 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954312 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954313 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135001 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135002 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135003 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135004 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135005 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41217 (Get FASTA)   NCBI Sequence Viewer  
  AAA41218 (Get FASTA)   NCBI Sequence Viewer  
  AAA57295 (Get FASTA)   NCBI Sequence Viewer  
  AAB59698 (Get FASTA)   NCBI Sequence Viewer  
  AAH78768 (Get FASTA)   NCBI Sequence Viewer  
  CAA33483 (Get FASTA)   NCBI Sequence Viewer  
  CAA36894 (Get FASTA)   NCBI Sequence Viewer  
  CAA36997 (Get FASTA)   NCBI Sequence Viewer  
  EDL97199 (Get FASTA)   NCBI Sequence Viewer  
  EDL97200 (Get FASTA)   NCBI Sequence Viewer  
  EDL97201 (Get FASTA)   NCBI Sequence Viewer  
  EDL97202 (Get FASTA)   NCBI Sequence Viewer  
  EDL97203 (Get FASTA)   NCBI Sequence Viewer  
  EDL97204 (Get FASTA)   NCBI Sequence Viewer  
  EDL97205 (Get FASTA)   NCBI Sequence Viewer  
  EDL97206 (Get FASTA)   NCBI Sequence Viewer  
  EDL97207 (Get FASTA)   NCBI Sequence Viewer  
  EDL97208 (Get FASTA)   NCBI Sequence Viewer  
  EDL97209 (Get FASTA)   NCBI Sequence Viewer  
  EDL97210 (Get FASTA)   NCBI Sequence Viewer  
  EDL97211 (Get FASTA)   NCBI Sequence Viewer  
  EDL97212 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065923
  ENSRNOP00000065923.3
GenBank Protein P07314 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446292   ⟸   NM_053840
- UniProtKB: Q6AZ32 (UniProtKB/Swiss-Prot),   Q63218 (UniProtKB/Swiss-Prot),   Q63217 (UniProtKB/Swiss-Prot),   P07314 (UniProtKB/Swiss-Prot),   A6JKJ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000076317   ⟸   ENSRNOT00000093521
Ensembl Acc Id: ENSRNOP00000076324   ⟸   ENSRNOT00000093430
Ensembl Acc Id: ENSRNOP00000065923   ⟸   ENSRNOT00000074533
RefSeq Acc Id: XP_038954313   ⟸   XM_039098385
- Peptide Label: isoform X1
- UniProtKB: Q6AZ32 (UniProtKB/Swiss-Prot),   Q63218 (UniProtKB/Swiss-Prot),   Q63217 (UniProtKB/Swiss-Prot),   P07314 (UniProtKB/Swiss-Prot),   A6JKJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954311   ⟸   XM_039098383
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038954310   ⟸   XM_039098382
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038954312   ⟸   XM_039098384
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063135003   ⟸   XM_063278933
- Peptide Label: isoform X1
- UniProtKB: Q6AZ32 (UniProtKB/Swiss-Prot),   Q63218 (UniProtKB/Swiss-Prot),   Q63217 (UniProtKB/Swiss-Prot),   P07314 (UniProtKB/Swiss-Prot),   A6JKJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135001   ⟸   XM_063278931
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063135004   ⟸   XM_063278934
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063135002   ⟸   XM_063278932
- Peptide Label: isoform X1
- UniProtKB: Q6AZ32 (UniProtKB/Swiss-Prot),   Q63218 (UniProtKB/Swiss-Prot),   Q63217 (UniProtKB/Swiss-Prot),   P07314 (UniProtKB/Swiss-Prot),   A6JKJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135005   ⟸   XM_063278935
- Peptide Label: isoform X1
- UniProtKB: Q6AZ32 (UniProtKB/Swiss-Prot),   Q63218 (UniProtKB/Swiss-Prot),   Q63217 (UniProtKB/Swiss-Prot),   P07314 (UniProtKB/Swiss-Prot),   A6JKJ2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112639   ⟸   ENSRNOT00000137128

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P07314-F1-model_v2 AlphaFold P07314 1-568 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2683 AgrOrtholog
BioCyc Gene G2FUF-4150 BioCyc
Ensembl Genes ENSRNOG00000047697 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074533 ENTREZGENE
  ENSRNOT00000074533.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.246.130 UniProtKB/Swiss-Prot
  3.60.20.40 UniProtKB/Swiss-Prot
InterPro GGT_CS UniProtKB/Swiss-Prot
  GGT_lsub_C UniProtKB/Swiss-Prot
  GGT_peptidase UniProtKB/Swiss-Prot
  GGT_ssub UniProtKB/Swiss-Prot
  Ntn_hydrolases_N UniProtKB/Swiss-Prot
KEGG Report rno:116568 UniProtKB/Swiss-Prot
NCBI Gene Ggt1 ENTREZGENE
PANTHER GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED UniProtKB/Swiss-Prot
  PTHR11686 UniProtKB/Swiss-Prot
Pfam G_glu_transpept UniProtKB/Swiss-Prot
PhenoGen Ggt1 PhenoGen
PRINTS GGTRANSPTASE UniProtKB/Swiss-Prot
PROSITE G_GLU_TRANSPEPTIDASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000047697 RatGTEx
Superfamily-SCOP SSF56235 UniProtKB/Swiss-Prot
UniProt A0ABK0M156_RAT UniProtKB/TrEMBL
  A6JKI9_RAT UniProtKB/TrEMBL
  A6JKJ2 ENTREZGENE, UniProtKB/TrEMBL
  A6JKJ6_RAT UniProtKB/TrEMBL
  GGT1_RAT UniProtKB/Swiss-Prot
  M0R8W8_RAT UniProtKB/TrEMBL
  P07314 ENTREZGENE
  Q63217 ENTREZGENE
  Q63218 ENTREZGENE
  Q6AZ32 ENTREZGENE
UniProt Secondary Q63217 UniProtKB/Swiss-Prot
  Q63218 UniProtKB/Swiss-Prot
  Q6AZ32 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-08-29 Ggt1  gamma-glutamyltransferase 1  Ggtp  gamma-glutamyl transpeptidase  Data merged from RGD:628784 737654 APPROVED
2004-09-10 Ggt1  gamma-glutamyltransferase 1    Gamma glutamyl-transferase 1  Name updated 1299863 APPROVED
2003-02-27 Ggtp  gamma-glutamyl transpeptidase      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Ggt1  Gamma glutamyl-transferase 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the proximal convolutions of the renal tubule of the kidney 632765
gene_regulation mRNAs increases from birth to the adult stage 632765
gene_transcript contains 8 exons and has two CCAAT boxes 632655