GGT3P (gamma-glutamyltransferase 3 pseudogene) - Rat Genome Database

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Gene: GGT3P (gamma-glutamyltransferase 3 pseudogene) Homo sapiens
Analyze
No known orthologs.
Symbol: GGT3P
Name: gamma-glutamyltransferase 3 pseudogene
RGD ID: 1350985
HGNC Page HGNC:4252
Description: Predicted to enable glutathione hydrolase activity. Predicted to be involved in several processes, including glutathione catabolic process; leukotriene D4 biosynthetic process; and peptide modification. Located in extracellular exosome.
Type: pseudo (Ensembl: transcribed_unprocessed_pseudogene)
RefSeq Status: VALIDATED
Previously known as: gamma-glutamyltransferase 3; GGT3; inactive glutathione hydrolase 2; LOC102724823
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: GGT1  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,773,689 - 18,791,961 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,773,825 - 18,791,223 (-)EnsemblGRCh38hg38GRCh38
GRCh372218,761,202 - 18,779,474 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,141,202 - 17,159,474 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map22q11.21NCBI
CHM1_12218,760,885 - 18,779,155 (-)NCBICHM1_1
T2T-CHM13v2.02219,147,114 - 19,165,401 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
cisplatin  (EXP)
triclosan  (EXP)
valproic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2573352   PMID:2904146   PMID:7906515   PMID:8104871   PMID:10737800   PMID:12477932   PMID:14715246   PMID:18357469   PMID:21873635   PMID:23533145  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:848
Count of miRNA genes:548
Interacting mature miRNAs:623
Transcripts:ENST00000412448, ENST00000430306, ENST00000445651, ENST00000453783
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
J05235  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map20p11.1UniSTS
Cytogenetic Map22q11.22UniSTS
Whitehead-YAC Contig Map22 UniSTS
GDB:190922  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map20p11.1UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map22q11.22UniSTS
RH69116  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map20p11.1UniSTS
GeneMap99-GB4 RH Map2217.11UniSTS
RH79893  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map20p11.1UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map22q11.22UniSTS
D22S732  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map20p11.1UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map22q11.22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 95 20 2 96
Low 43 623 13 86 11 329 1 14 215 360 814 1 4 174
Below cutoff 1410 1307 654 417 894 281 2037 827 2729 106 637 524 142 573 1292 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000412448
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2218,773,665 - 18,805,479 (-)Ensembl
RefSeq Acc Id: ENST00000430306
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2218,794,598 - 18,825,001 (-)Ensembl
RefSeq Acc Id: ENST00000445651
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2218,794,531 - 18,843,399 (-)Ensembl
RefSeq Acc Id: ENST00000453783
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2218,773,825 - 18,791,223 (-)Ensembl
RefSeq Acc Id: NR_003267
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382218,773,689 - 18,791,961 (-)NCBI
GRCh372218,761,202 - 18,779,474 (-)RGD
Build 362217,141,202 - 17,159,474 (-)NCBI Archive
CHM1_12218,760,885 - 18,779,155 (-)NCBI
T2T-CHM13v2.02219,147,114 - 19,165,401 (-)NCBI
Sequence:
Protein Sequences
GenBank Protein A6NGU5 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6NGU5-F1-model_v2 AlphaFold A6NGU5 1-568 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:4252 AgrOrtholog
COSMIC GGT3P COSMIC
Ensembl Genes ENSG00000197421 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000453783 ENTREZGENE
Gene3D-CATH 1.10.246.130 UniProtKB/Swiss-Prot
  3.60.20.40 UniProtKB/Swiss-Prot
GTEx ENSG00000197421 GTEx
HGNC ID HGNC:4252 ENTREZGENE
Human Proteome Map GGT3P Human Proteome Map
InterPro GGT_lsub_C UniProtKB/Swiss-Prot
  GGT_peptidase UniProtKB/Swiss-Prot
  GGT_ssub UniProtKB/Swiss-Prot
  Ntn_hydrolases_N UniProtKB/Swiss-Prot
NCBI Gene 2679 ENTREZGENE
PANTHER GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED UniProtKB/Swiss-Prot
  PTHR11686 UniProtKB/Swiss-Prot
Pfam G_glu_transpept UniProtKB/Swiss-Prot
PRINTS GGTRANSPTASE UniProtKB/Swiss-Prot
PROSITE G_GLU_TRANSPEPTIDASE UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56235 UniProtKB/Swiss-Prot
UniProt A6NGU5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-05 GGT3P  gamma-glutamyltransferase 3 pseudogene  LOC102724823  inactive glutathione hydrolase 2  Data merged from RGD:38654237 737654 PROVISIONAL