Coq3 (coenzyme Q3 methyltransferase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Coq3 (coenzyme Q3 methyltransferase) Rattus norvegicus
Analyze
Symbol: Coq3
Name: coenzyme Q3 methyltransferase
RGD ID: 2380
Description: Predicted to enable 3-demethylubiquinol 3-O-methyltransferase activity; 3-demethylubiquinone 3-O-methyltransferase activity; and polyprenyldihydroxybenzoate methyltransferase activity. Involved in methylation and ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be part of ubiquinone biosynthesis complex. Predicted to be active in mitochondrial matrix. Orthologous to human COQ3 (coenzyme Q3, methyltransferase); PARTICIPATES IN ubiquinone biosynthetic pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2-polyprenyl-6-hydroxyphenol methylase; 2-polyprenyl-6-hydroxyphenyl methylase; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone 3-O-methyltransferase; 3-demethylubiquinone-9 3-methyltransferase; coenzyme Q (ubiquinone); coenzyme q (ubiquinone) biosynthetic enzyme 3; coenzyme Q3 homolog, methyltransferase; coenzyme Q3 homolog, methyltransferase (S. cerevisiae); coenzyme Q3 homolog, methyltransferase (yeast); DHHB methyltransferase; DHHB-MT; DHHB-MTase; dihydroxyhexaprenylbenzoate methyltransferase; hexaprenyldihydroxybenzoate methyltransferase; hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; MGC156658; polyprenyldihydroxybenzoate methyltransferase; ubiquinone biosynthesis O-methyltransferase, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,226,313 - 40,257,383 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl540,226,368 - 40,257,617 (+)EnsemblGRCr8
mRatBN7.2535,429,567 - 35,460,613 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,429,574 - 35,460,607 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx537,568,779 - 37,585,044 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,161,507 - 39,177,768 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0539,101,017 - 39,117,278 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0536,024,673 - 36,056,664 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl536,024,649 - 36,056,669 (+)Ensemblrn6Rnor6.0
Rnor_5.0540,693,937 - 40,710,202 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4536,640,718 - 36,656,981 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera534,458,047 - 34,473,986 (+)NCBICelera
RGSC_v3.1536,640,896 - 36,657,160 (-)NCBI
Cytogenetic Map5q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trimethylbenzene  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
amiodarone  (EXP,ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
calcitriol  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
diuron  (EXP)
endosulfan  (EXP)
ethanol  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
isobutanol  (ISO)
L-ethionine  (EXP)
methimazole  (EXP)
N-nitrosodiethylamine  (EXP)
okadaic acid  (ISO)
omeprazole  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP,ISO)
quercetin  (ISO)
quercitrin  (ISO)
rac-lactic acid  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
tolcapone  (EXP)
topotecan  (EXP)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cloning of a rat cDNA encoding dihydroxypolyprenylbenzoate methyltransferase by functional complementation of a Saccharomyces cerevisiae mutant deficient in ubiquinone biosynthesis. Marbois BN, etal., Gene 1994 Jan 28;138(1-2):213-7.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. Poon WW, etal., J Biol Chem. 1999 Jul 30;274(31):21665-72.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10777520   PMID:15489334   PMID:18614015   PMID:26316108  


Genomics

Comparative Map Data
Coq3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,226,313 - 40,257,383 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl540,226,368 - 40,257,617 (+)EnsemblGRCr8
mRatBN7.2535,429,567 - 35,460,613 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,429,574 - 35,460,607 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx537,568,779 - 37,585,044 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,161,507 - 39,177,768 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0539,101,017 - 39,117,278 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0536,024,673 - 36,056,664 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl536,024,649 - 36,056,669 (+)Ensemblrn6Rnor6.0
Rnor_5.0540,693,937 - 40,710,202 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4536,640,718 - 36,656,981 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera534,458,047 - 34,473,986 (+)NCBICelera
RGSC_v3.1536,640,896 - 36,657,160 (-)NCBI
Cytogenetic Map5q21NCBI
COQ3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38699,369,401 - 99,394,195 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl699,369,401 - 99,394,207 (-)Ensemblhg38GRCh38
GRCh37699,817,277 - 99,842,071 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36699,924,069 - 99,948,803 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34699,924,072 - 99,948,801NCBI
Celera6100,461,523 - 100,486,230 (-)NCBICelera
Cytogenetic Map6q16.2NCBI
HuRef697,257,764 - 97,282,457 (-)NCBIHuRef
CHM1_16100,080,413 - 100,105,111 (-)NCBICHM1_1
T2T-CHM13v2.06100,543,769 - 100,568,541 (-)NCBIT2T-CHM13v2.0
Coq3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39421,879,646 - 21,912,163 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl421,879,673 - 21,912,162 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38421,879,646 - 21,912,163 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl421,879,673 - 21,912,162 (+)Ensemblmm10GRCm38
MGSCv37421,806,822 - 21,839,273 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36421,970,510 - 22,002,961 (+)NCBIMGSCv36mm8
Celera421,624,381 - 21,656,627 (+)NCBICelera
Cytogenetic Map4A3NCBI
cM Map49.11NCBI
Coq3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541125,243,684 - 25,268,225 (-)NCBIChiLan1.0ChiLan1.0
COQ3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25119,415,888 - 119,441,101 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16117,297,073 - 117,322,285 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0697,210,293 - 97,235,234 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16101,092,782 - 101,117,481 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6101,092,782 - 101,117,485 (-)EnsemblpanPan2panpan1.1
COQ3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11257,589,993 - 57,606,486 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1257,590,662 - 57,606,447 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1257,346,528 - 57,364,340 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01258,411,990 - 58,428,072 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1258,409,953 - 58,428,040 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01257,615,466 - 57,631,408 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01257,860,596 - 57,876,612 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Coq3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494692,526,750 - 92,547,673 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936651979,053 - 1,000,871 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936651983,397 - 1,000,669 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COQ3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl166,232,181 - 66,346,575 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1166,321,288 - 66,347,088 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
COQ3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11374,477,313 - 74,501,841 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604046,810,795 - 46,836,136 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Coq3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248105,613,750 - 5,670,544 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248105,613,716 - 5,666,379 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Coq3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11121,433,699 - 121,460,249 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Coq3
140 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:139
Count of miRNA genes:113
Interacting mature miRNAs:127
Transcripts:ENSRNOT00000013384
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)53113042148841739Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
RH131083  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2535,460,312 - 35,460,508 (+)MAPPERmRatBN7.2
Rnor_6.0536,056,364 - 36,056,559NCBIRnor6.0
Rnor_5.0540,709,908 - 40,710,103UniSTSRnor5.0
RGSC_v3.4536,640,815 - 36,641,010UniSTSRGSC3.4
Celera534,473,692 - 34,473,887UniSTS
RH 3.4 Map5199.8UniSTS
Cytogenetic Map5q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000013384   ⟹   ENSRNOP00000013384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl540,226,368 - 40,257,617 (+)Ensembl
mRatBN7.2 Ensembl535,429,574 - 35,460,607 (+)Ensembl
Rnor_6.0 Ensembl536,024,649 - 36,056,669 (+)Ensembl
RefSeq Acc Id: NM_019187   ⟹   NP_062060
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,241,107 - 40,257,372 (+)NCBI
mRatBN7.2535,444,340 - 35,460,607 (+)NCBI
Rnor_6.0536,040,393 - 36,056,658 (+)NCBI
Rnor_5.0540,693,937 - 40,710,202 (+)NCBI
RGSC_v3.4536,640,718 - 36,656,981 (-)RGD
Celera534,458,047 - 34,473,986 (+)RGD
Sequence:
RefSeq Acc Id: XM_017593201   ⟹   XP_017448690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,226,313 - 40,257,383 (+)NCBI
mRatBN7.2535,429,567 - 35,460,613 (+)NCBI
Rnor_6.0536,024,673 - 36,056,664 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109358   ⟹   XP_038965286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,226,350 - 40,257,383 (+)NCBI
mRatBN7.2535,429,579 - 35,460,613 (+)NCBI
RefSeq Acc Id: NP_062060   ⟸   NM_019187
- UniProtKB: Q642D7 (UniProtKB/Swiss-Prot),   Q63159 (UniProtKB/Swiss-Prot),   A0JN24 (UniProtKB/Swiss-Prot),   A6IIF5 (UniProtKB/TrEMBL),   Q4G082 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448690   ⟸   XM_017593201
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000013384   ⟸   ENSRNOT00000013384
RefSeq Acc Id: XP_038965286   ⟸   XM_039109358
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63159-F1-model_v2 AlphaFold Q63159 1-345 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693598
Promoter ID:EPDNEW_R4123
Type:multiple initiation site
Name:Coq3_1
Description:coenzyme Q3 methyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0536,024,700 - 36,024,760EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2380 AgrOrtholog
BioCyc Gene G2FUF-41810 BioCyc
Ensembl Genes ENSRNOG00000009974 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013384 ENTREZGENE
  ENSRNOT00000013384.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.150 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7191748 IMAGE-MGC_LOAD
  IMAGE:7323432 IMAGE-MGC_LOAD
  IMAGE:8370738 IMAGE-MGC_LOAD
InterPro SAM-dependent_MTases UniProtKB/Swiss-Prot
  UbiG_MeTrfase UniProtKB/Swiss-Prot
KEGG Report rno:29309 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112616 IMAGE-MGC_LOAD
  MGC:156658 IMAGE-MGC_LOAD
  MGC:93489 IMAGE-MGC_LOAD
NCBI Gene 29309 ENTREZGENE
PANTHER METHYLTRANSFERASE UniProtKB/Swiss-Prot
  UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam Methyltransf_23 UniProtKB/Swiss-Prot
PhenoGen Coq3 PhenoGen
RatGTEx ENSRNOG00000009974 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot
TIGR TC217815
UniProt A0JN24 ENTREZGENE
  A6IIF5 ENTREZGENE, UniProtKB/TrEMBL
  COQ3_RAT UniProtKB/Swiss-Prot
  Q4G082 ENTREZGENE, UniProtKB/TrEMBL
  Q63159 ENTREZGENE
  Q642D7 ENTREZGENE
UniProt Secondary A0JN24 UniProtKB/Swiss-Prot
  Q642D7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-09-16 Coq3  coenzyme Q3 methyltransferase  Coq3  coenzyme Q3 homolog, methyltransferase (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-15 Coq3  coenzyme Q3 homolog, methyltransferase (S. cerevisiae)  Coq3  coenzyme Q3 homolog, methyltransferase (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Coq3  coenzyme Q3 homolog, methyltransferase (yeast)    coenzyme q (ubiquinone) biosynthetic enzyme 3  Name updated 1299863 APPROVED
2002-06-10 Coq3  coenzyme q (ubiquinone) biosynthetic enzyme 3      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function putative 3,4-dihydroxy-5-polyprenylbenzoate-MTase 69814
gene_function catalyzes the fourth step in biosynthesis of ubiquinone (coenzyme Q) from p-hydroxybenzoic acid in functional complementation assay in S. cerevisiae 69814
gene_process may participate in synthesis of ubiquinone 69814