Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Immp2l | Rat | (+)-dexrazoxane | multiple interactions | ISO | Immp2l (Mus musculus) | 6480464 | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of IMMP2L mRNA | CTD | PMID:26873546 | Immp2l | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of IMMP2L mRNA] | CTD | PMID:31150632 | Immp2l | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Immp2l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of IMMP2L mRNA | CTD | PMID:36331819 | Immp2l | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of IMMP2L mRNA | CTD | PMID:22206623 | Immp2l | Rat | 17beta-estradiol | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | Estradiol results in decreased expression of IMMP2L mRNA | CTD | PMID:19484750|PMID:39298647 | Immp2l | Rat | 2,2',5,5'-tetrachlorobiphenyl | increases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | 2,5,2',5'-tetrachlorobiphenyl results in increased expression of IMMP2L mRNA | CTD | PMID:36804509 | Immp2l | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Immp2l (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of IMMP2L mRNA | CTD | PMID:21570461 | Immp2l | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of IMMP2L mRNA | CTD | PMID:20188158 | Immp2l | Rat | 3-chloropropane-1,2-diol | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | alpha-Chlorohydrin results in decreased expression of IMMP2L mRNA | CTD | PMID:35690182 | Immp2l | Rat | 3-methylcholanthrene | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | Methylcholanthrene results in decreased expression of IMMP2L mRNA | CTD | PMID:20713471 | Immp2l | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of IMMP2L mRNA | CTD | PMID:18648102 | Immp2l | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Immp2l (Mus musculus) | 6480464 | bisphenol S affects the methylation of IMMP2L gene | CTD | PMID:31683443 | Immp2l | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Immp2l (Mus musculus) | 6480464 | bisphenol S results in increased expression of IMMP2L mRNA | CTD | PMID:40203079 | Immp2l | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | Fenretinide results in decreased expression of IMMP2L mRNA | CTD | PMID:28973697 | Immp2l | Rat | 7,12-dimethyltetraphene | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | 9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of IMMP2L mRNA | CTD | PMID:32553695 | Immp2l | Rat | aflatoxin B1 | affects expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of IMMP2L protein | CTD | PMID:20106945 | Immp2l | Rat | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of IMMP2L mRNA | CTD | PMID:33354967 | Immp2l | Rat | aflatoxin B1 | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of IMMP2L mRNA | CTD | PMID:21641981|PMID:27153756|PMID:32234424|PMID:35690182 | Immp2l | Rat | aflatoxin B1 | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of IMMP2L mRNA | CTD | PMID:19770486 | Immp2l | Rat | Aflatoxin B2 alpha | increases methylation | ISO | IMMP2L (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of IMMP2L exon | CTD | PMID:30157460 | Immp2l | Rat | all-trans-retinoic acid | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of IMMP2L mRNA | CTD | PMID:33167477 | Immp2l | Rat | AM-251 | increases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | AM 251 results in increased expression of IMMP2L mRNA | CTD | PMID:16500647 | Immp2l | Rat | aristolochic acid A | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of IMMP2L mRNA | CTD | PMID:33212167 | Immp2l | Rat | Aroclor 1254 | increases expression | ISO | Immp2l (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of IMMP2L mRNA | CTD | PMID:23650126 | Immp2l | Rat | arsenite(3-) | multiple interactions | ISO | IMMP2L (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to IMMP2L mRNA] | CTD | PMID:32406909 | Immp2l | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of IMMP2L gene | CTD | PMID:35440735 | Immp2l | Rat | benzo[a]pyrene | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | Benzo(a)pyrene metabolite results in decreased expression of IMMP2L mRNA; Benzo(a)pyrene results in decreased expression of more ... | CTD | PMID:19770486|PMID:20713471|PMID:21569818|PMID:21715664|PMID:22610609|PMID:32553695 | Immp2l | Rat | benzo[a]pyrene | affects methylation | ISO | IMMP2L (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of IMMP2L intron | CTD | PMID:30157460 | Immp2l | Rat | benzo[a]pyrene | decreases methylation | ISO | Immp2l (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of IMMP2L intron | CTD | PMID:27901495 | Immp2l | Rat | benzo[a]pyrene | decreases methylation | ISO | IMMP2L (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of IMMP2L 5' UTR; Benzo(a)pyrene results in decreased methylation of more ... | CTD | PMID:27901495 | Immp2l | Rat | benzo[a]pyrene | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of IMMP2L mRNA | CTD | PMID:20064835|PMID:20106945|PMID:21632981|PMID:22316170|PMID:26238291|PMID:32234424|PMID:35690182 | Immp2l | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of IMMP2L mRNA | CTD | PMID:26238291 | Immp2l | Rat | benzo[b]fluoranthene | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of IMMP2L mRNA | CTD | PMID:26377693 | Immp2l | Rat | benzo[e]pyrene | decreases methylation | ISO | IMMP2L (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of IMMP2L intron | CTD | PMID:30157460 | Immp2l | Rat | bis(2-chloroethyl) sulfide | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Mustard Gas results in decreased expression of IMMP2L mRNA | CTD | PMID:25102026 | Immp2l | Rat | bisphenol A | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | bisphenol A results in decreased expression of IMMP2L mRNA | CTD | PMID:26063408 | Immp2l | Rat | bisphenol A | increases expression | ISO | Immp2l (Mus musculus) | 6480464 | bisphenol A results in increased expression of IMMP2L mRNA | CTD | PMID:32156529 | Immp2l | Rat | bisphenol A | decreases methylation | ISO | IMMP2L (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of IMMP2L gene | CTD | PMID:31601247 | Immp2l | Rat | Butylbenzyl phthalate | increases methylation | ISO | Immp2l (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of IMMP2L intron | CTD | PMID:28392331 | Immp2l | Rat | cadmium atom | increases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Cadmium results in increased expression of IMMP2L mRNA | CTD | PMID:34773240 | Immp2l | Rat | cadmium atom | multiple interactions | ISO | IMMP2L (Homo sapiens) | 6480464 | Selenium inhibits the reaction [Cadmium results in increased expression of IMMP2L mRNA] | CTD | PMID:34773240 | Immp2l | Rat | cadmium atom | multiple interactions | ISO | Immp2l (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IMMP2L more ... | CTD | PMID:37236586 | Immp2l | Rat | cadmium dichloride | multiple interactions | ISO | Immp2l (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IMMP2L more ... | CTD | PMID:37236586 | Immp2l | Rat | carbamazepine | affects expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Carbamazepine affects the expression of IMMP2L mRNA | CTD | PMID:25979313 | Immp2l | Rat | carbon nanotube | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of IMMP2L mRNA | CTD | PMID:25554681 | Immp2l | Rat | CGP 52608 | multiple interactions | ISO | IMMP2L (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to IMMP2L gene] | CTD | PMID:28238834 | Immp2l | Rat | chromium(6+) | affects expression | ISO | Immp2l (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of IMMP2L mRNA | CTD | PMID:28472532 | Immp2l | Rat | cisplatin | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | Cisplatin results in decreased expression of IMMP2L mRNA | CTD | PMID:25270620|PMID:40618947 | Immp2l | Rat | cisplatin | multiple interactions | ISO | IMMP2L (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of IMMP2L mRNA | CTD | PMID:27392435 | Immp2l | Rat | cisplatin | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of IMMP2L mRNA | CTD | PMID:27392435|PMID:27594783 | Immp2l | Rat | copper(II) sulfate | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of IMMP2L mRNA | CTD | PMID:19549813 | Immp2l | Rat | doxorubicin | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of IMMP2L mRNA | CTD | PMID:26873546 | Immp2l | Rat | doxorubicin | multiple interactions | ISO | Immp2l (Mus musculus) | 6480464 | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of IMMP2L mRNA | CTD | PMID:26873546 | Immp2l | Rat | elemental selenium | multiple interactions | ISO | IMMP2L (Homo sapiens) | 6480464 | Selenium inhibits the reaction [Cadmium results in increased expression of IMMP2L mRNA] | CTD | PMID:34773240 | Immp2l | Rat | ethyl methanesulfonate | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of IMMP2L mRNA | CTD | PMID:23649840 | Immp2l | Rat | fenthion | increases expression | ISO | Immp2l (Mus musculus) | 6480464 | Fenthion results in increased expression of IMMP2L mRNA | CTD | PMID:34813904 | Immp2l | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of IMMP2L mRNA | CTD | PMID:24793618 | Immp2l | Rat | formaldehyde | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of IMMP2L mRNA | CTD | PMID:23649840 | Immp2l | Rat | inulin | multiple interactions | ISO | Immp2l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of IMMP2L mRNA | CTD | PMID:36331819 | Immp2l | Rat | irinotecan | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Irinotecan analog results in decreased expression of IMMP2L mRNA | CTD | PMID:18927307 | Immp2l | Rat | Lasiocarpine | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | lasiocarpine results in decreased expression of IMMP2L mRNA | CTD | PMID:32234424|PMID:35690182 | Immp2l | Rat | methapyrilene | decreases methylation | ISO | IMMP2L (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of IMMP2L intron | CTD | PMID:30157460 | Immp2l | Rat | methyl methanesulfonate | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of IMMP2L mRNA | CTD | PMID:23649840 | Immp2l | Rat | methylmercury chloride | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of IMMP2L mRNA | CTD | PMID:28001369 | Immp2l | Rat | N-Nitrosopyrrolidine | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of IMMP2L mRNA | CTD | PMID:32234424|PMID:35690182 | Immp2l | Rat | O-methyleugenol | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of IMMP2L mRNA | CTD | PMID:32234424|PMID:35690182 | Immp2l | Rat | okadaic acid | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of IMMP2L mRNA | CTD | PMID:38832940 | Immp2l | Rat | ozone | multiple interactions | ISO | IMMP2L (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of IMMP2L mRNA | CTD | PMID:35430440 | Immp2l | Rat | paracetamol | affects expression | ISO | Immp2l (Mus musculus) | 6480464 | Acetaminophen affects the expression of IMMP2L mRNA | CTD | PMID:17562736 | Immp2l | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Immp2l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of IMMP2L mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Immp2l | Rat | perfluorooctanoic acid | increases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of IMMP2L mRNA | CTD | PMID:35690182 | Immp2l | Rat | pirinixic acid | increases expression | ISO | Immp2l (Mus musculus) | 6480464 | pirinixic acid results in increased expression of IMMP2L mRNA | CTD | PMID:23811191 | Immp2l | Rat | selenium atom | multiple interactions | ISO | IMMP2L (Homo sapiens) | 6480464 | Selenium inhibits the reaction [Cadmium results in increased expression of IMMP2L mRNA] | CTD | PMID:34773240 | Immp2l | Rat | sodium arsenate | increases expression | ISO | Immp2l (Mus musculus) | 6480464 | sodium arsenate results in increased expression of IMMP2L mRNA | CTD | PMID:30953684 | Immp2l | Rat | sodium arsenite | decreases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of IMMP2L mRNA | CTD | PMID:38568856 | Immp2l | Rat | sodium dichromate | decreases expression | EXP | | 6480464 | sodium bichromate results in decreased expression of IMMP2L mRNA | CTD | PMID:25993096 | Immp2l | Rat | testosterone | increases expression | ISO | Immp2l (Mus musculus) | 6480464 | Testosterone deficiency results in increased expression of IMMP2L mRNA | CTD | PMID:33848595 | Immp2l | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of IMMP2L mRNA] | CTD | PMID:31150632 | Immp2l | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of IMMP2L mRNA | CTD | PMID:31150632 | Immp2l | Rat | titanium dioxide | affects expression | ISO | Immp2l (Mus musculus) | 6480464 | titanium dioxide affects the expression of IMMP2L mRNA | CTD | PMID:23557971 | Immp2l | Rat | titanium dioxide | decreases methylation | ISO | Immp2l (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of IMMP2L gene | CTD | PMID:35295148 | Immp2l | Rat | trovafloxacin | decreases expression | ISO | Immp2l (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of IMMP2L mRNA | CTD | PMID:35537566 | Immp2l | Rat | urethane | increases expression | ISO | IMMP2L (Homo sapiens) | 6480464 | Urethane results in increased expression of IMMP2L mRNA | CTD | PMID:28818685 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















