Rps12l1 (ribosomal protein S12 like 1) - Rat Genome Database

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Gene: Rps12l1 (ribosomal protein S12 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps12l1
Name: ribosomal protein S12 like 1
RGD ID: 2321884
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in maintenance of translational fidelity and ribosomal small subunit biogenesis. Part of cytosolic large ribosomal subunit and cytosolic small ribosomal subunit. Orthologous to human RPS12 (ribosomal protein S12).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 40S ribosomal protein S12; 40S ribosomal protein S12-like; LOC100360573; ribosomal protein S12-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81951,253,770 - 51,254,409 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1951,253,687 - 51,254,435 (+)EnsemblGRCr8
mRatBN7.21934,343,930 - 34,344,569 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1934,343,929 - 34,344,569 (+)EnsemblmRatBN7.2
Rnor_6.01938,619,672 - 38,620,321 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,619,764 - 38,620,298 (+)Ensemblrn6Rnor6.0
Rnor_5.01949,487,604 - 49,488,240 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41936,293,808 - 36,294,365 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1933,770,614 - 33,771,263 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:925037   PMID:3308890   PMID:3366245   PMID:25002582  


Genomics

Variants

.
Variants in Rps12l1
13 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:41
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000027225
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 148 83 82 51 92 51 6 339 192 11 127 72 84 31 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000027225   ⟹   ENSRNOP00000027226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1951,253,687 - 51,254,435 (+)Ensembl
mRatBN7.2 Ensembl1934,343,929 - 34,344,569 (+)Ensembl
Rnor_6.0 Ensembl1938,619,764 - 38,620,298 (+)Ensembl
RefSeq Acc Id: NM_001408967   ⟹   NP_001395896
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81951,253,770 - 51,254,409 (+)NCBI
mRatBN7.21934,343,930 - 34,344,569 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001395896 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027226
Ensembl Acc Id: ENSRNOP00000027226   ⟸   ENSRNOT00000027225
RefSeq Acc Id: NP_001395896   ⟸   NM_001408967
- UniProtKB: P63324 (UniProtKB/Swiss-Prot),   D3ZHB3 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHB3-F1-model_v2 AlphaFold D3ZHB3 1-132 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701118
Promoter ID:EPDNEW_R11635
Type:multiple initiation site
Name:LOC100360573_1
Description:ribosomal protein S12-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01938,619,680 - 38,619,740EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2321884 AgrOrtholog
BioCyc Gene G2FUF-5780 BioCyc
Ensembl Genes ENSRNOG00000020093 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000027225 ENTREZGENE
Gene3D-CATH 3.30.1330.30 UniProtKB/Swiss-Prot
InterPro Ribosomal_eL30-like_sf UniProtKB/Swiss-Prot
  Ribosomal_eL8/eL30/eS12/Gad45 UniProtKB/Swiss-Prot
  Ribosomal_eS12 UniProtKB/Swiss-Prot
  Ribosomal_eS12_CS UniProtKB/Swiss-Prot
NCBI Gene 100360573 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S12 UniProtKB/Swiss-Prot
Pfam Ribosomal_L7Ae UniProtKB/Swiss-Prot
PhenoGen Rps12l1 PhenoGen
PRINTS RIBSOMALS12E UniProtKB/Swiss-Prot
PROSITE RIBOSOMAL_S12E UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020093 RatGTEx
Superfamily-SCOP L30e-like UniProtKB/Swiss-Prot
UniProt D3ZHB3 ENTREZGENE, UniProtKB/TrEMBL
  P63324 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P09388 UniProtKB/Swiss-Prot
  P12728 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rps12l1  ribosomal protein S12 like 1  LOC100360573  ribosomal protein S12-like  Symbol and Name Changed 1299863 APPROVED
2010-05-06 LOC100360573  ribosomal protein S12-like      Symbol and Name status set to provisional 70820 PROVISIONAL