Ypel1 (yippee-like 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Ypel1 (yippee-like 1) Rattus norvegicus
Analyze
Symbol: Ypel1
Name: yippee-like 1
RGD ID: 2321291
Description: Orthologous to human YPEL1 (yippee like 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; fenvalerate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100360867; yippee-like 1 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,426,012 - 97,440,646 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21183,921,799 - 83,936,409 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01188,171,401 - 88,186,000 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,173,890 - 88,180,542 (-)Ensemblrn6Rnor6.0
Rnor_5.01191,224,741 - 91,238,647 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,929,479 - 85,936,364 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1182,677,482 - 82,692,081 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-methoxyethanol  (EXP)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
CGP 52608  (ISO)
chloroethene  (ISO)
choline  (ISO)
dibutyl phthalate  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
fenamidone  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
L-methionine  (ISO)
methapyrilene  (ISO)
niclosamide  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
pentanal  (ISO)
phenylmercury acetate  (ISO)
propanal  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ypel1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,426,012 - 97,440,646 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21183,921,799 - 83,936,409 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01188,171,401 - 88,186,000 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,173,890 - 88,180,542 (-)Ensemblrn6Rnor6.0
Rnor_5.01191,224,741 - 91,238,647 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,929,479 - 85,936,364 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1182,677,482 - 82,692,081 (-)NCBICelera
Cytogenetic Map11q23NCBI
YPEL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,697,536 - 21,735,794 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2221,697,536 - 21,735,794 (-)Ensemblhg38GRCh38
GRCh372222,051,825 - 22,090,083 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,381,825 - 20,420,071 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342220,376,381 - 20,414,625NCBI
Celera225,869,356 - 5,907,602 (-)NCBICelera
Cytogenetic Map22q11.21-q11.22NCBI
HuRef225,009,474 - 5,047,359 (-)NCBIHuRef
CHM1_12222,052,019 - 22,090,249 (-)NCBICHM1_1
T2T-CHM13v2.02222,111,014 - 22,149,275 (-)NCBIT2T-CHM13v2.0
Ypel1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,887,454 - 16,904,912 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,887,560 - 16,904,909 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381617,070,139 - 17,087,048 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,069,696 - 17,087,045 (+)Ensemblmm10GRCm38
MGSCv371617,070,404 - 17,086,781 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361616,983,874 - 17,000,251 (+)NCBIMGSCv36mm8
Celera1617,643,100 - 17,659,477 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.58NCBI
Ypel1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,400,654 - 17,423,896 (+)Ensembl
ChiLan1.0NW_00495544217,400,655 - 17,423,896 (+)NCBIChiLan1.0ChiLan1.0
YPEL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22331,242,950 - 31,281,211 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12233,791,680 - 33,829,957 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0223,820,354 - 3,858,632 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12220,306,577 - 20,340,767 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2220,306,577 - 20,340,773 (-)EnsemblpanPan2panpan1.1
YPEL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,967,997 - 30,992,111 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,968,334 - 30,992,334 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2630,925,222 - 30,949,224 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02632,373,733 - 32,398,278 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2632,371,581 - 32,398,278 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12630,420,895 - 30,446,850 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02630,044,434 - 30,070,539 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02631,134,454 - 31,161,039 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ypel1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,769,878 - 140,795,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366191,958,370 - 1,981,350 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366191,958,370 - 1,984,182 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YPEL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,190,798 - 50,208,256 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11450,190,641 - 50,208,732 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,641,158 - 53,656,696 (+)NCBISscrofa10.2Sscrofa10.2susScr3
YPEL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,378,483 - 4,409,498 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,400,451 - 4,409,228 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660852,589,654 - 2,623,792 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ypel1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247471,248,026 - 1,274,869 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247471,248,026 - 1,274,909 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ypel1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v142,345,322 - 2,358,238 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:35
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000002539
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat

Markers in Region
RH135247  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,927,311 - 83,927,509 (+)MAPPERmRatBN7.2
Rnor_6.01188,176,916 - 88,177,113NCBIRnor6.0
Rnor_5.01191,229,581 - 91,229,778UniSTSRnor5.0
RGSC_v3.41185,932,738 - 85,932,935UniSTSRGSC3.4
Celera1182,682,997 - 82,683,194UniSTS
RH 3.4 Map11733.22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 161 89 88 57 88 57 6 349 187 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002539   ⟹   ENSRNOP00000002539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1188,173,890 - 88,180,542 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085475   ⟹   ENSRNOP00000071004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1188,173,890 - 88,177,448 (-)Ensembl
RefSeq Acc Id: NM_001426989   ⟹   NP_001413918
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,426,012 - 97,440,566 (-)NCBI
RefSeq Acc Id: XM_008768928   ⟹   XP_008767150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,426,687 - 97,440,646 (-)NCBI
mRatBN7.21183,921,799 - 83,936,409 (-)NCBI
Rnor_6.01188,171,401 - 88,186,000 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063270226   ⟹   XP_063126296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,426,687 - 97,440,645 (-)NCBI
RefSeq Acc Id: XM_063270227   ⟹   XP_063126297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,426,687 - 97,440,646 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001413918 (Get FASTA)   NCBI Sequence Viewer  
  XP_008767150 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126296 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126297 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77870 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000101248.1
  ENSRNOP00000106901.1
RefSeq Acc Id: XP_008767150   ⟸   XM_008768928
- Peptide Label: isoform X1
- UniProtKB: A6JSN7 (UniProtKB/TrEMBL),   A6K0A1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002539   ⟸   ENSRNOT00000002539
Ensembl Acc Id: ENSRNOP00000071004   ⟸   ENSRNOT00000085475
RefSeq Acc Id: NP_001413918   ⟸   NM_001426989
- UniProtKB: A6JSN7 (UniProtKB/TrEMBL),   A6K0A1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126297   ⟸   XM_063270227
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063126296   ⟸   XM_063270226
- Peptide Label: isoform X2
Protein Domains
Yippee

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9Y3-F1-model_v2 AlphaFold D4A9Y3 1-118 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2321291 AgrOrtholog
BioCyc Gene G2FUF-20566 BioCyc
Ensembl Genes ENSRNOG00000001858 Ensembl
  ENSRNOG00000077135 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000122751.1 UniProtKB/TrEMBL
  ENSRNOT00000140142.1 UniProtKB/TrEMBL
InterPro Yippee UniProtKB/TrEMBL
  Yippee/Mis18/Cereblon UniProtKB/TrEMBL
  Yippee_fam UniProtKB/TrEMBL
NCBI Gene 100360867 ENTREZGENE
PANTHER PROTEIN YIPPEE-LIKE CG15309-RELATED UniProtKB/TrEMBL
Pfam Yippee-Mis18 UniProtKB/TrEMBL
PhenoGen Ypel1 PhenoGen
PROSITE YIPPEE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001858 RatGTEx
  ENSRNOG00000077135 RatGTEx
UniProt A0ABK0LA44_RAT UniProtKB/TrEMBL
  A0ABK0LM88_RAT UniProtKB/TrEMBL
  A6JSN7 ENTREZGENE, UniProtKB/TrEMBL
  A6K0A1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-30 Ypel1  yippee-like 1  Ypel1  yippee-like 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-08-09 Ypel1  yippee-like 1 (Drosophila)  LOC100360867  yippee-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100360867  yippee-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL