Gene:	Cd8b ( Rattus norvegicus ) CD8b molecule
Description:	a marker for cytotoxic T cells; involved in cell-cell interactions
Synonyms:	Cd8b1; CD8 antigen beta chain; CD8 antigen, beta chain; CD8 antigen beta-chain;
ArrayIDs:	X04310_at; 5892693; 5845048; 6239055; 1387739_at; 6072162; 6170286;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: CD8B     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Cd8b1     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Cd8b genome assembly 3.1 4 104780934 - 104797161     Rat Celera Assembly 4 92485472 - 92501403     RGSC genome assembly v3.4 4 104536454 - 104552683     Cytogenetic 4 q33 Mus musculus Cd8b1 Mouse genome assembly build 36.1 6 71272806 - 71287445     Cytogenetic 6 6 C1 Homo sapiens CD8B human genome assembly 2 86989886 - 87000696     Human genome assembly build 36.2 2 86895971 - 86942549     Cytogenetic 2 p12   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein binding (details...)
Biological Process	Gene Ontology regulation of defense response to virus by virus,  immune response (details...)
Cellular Component	Gene Ontology early endosome,  membrane,  integral to membrane ...  (details...)
Homology	Note Reference homologous to immunoglobulin and T-cell receptor V domains 727767
External Links
Databases	DATABASE ID SOURCE SMART: IGv IPI PROSITE: IG_LIKE IPI UNIPARC: UPI00001273BA IPI KEGG Report: rno:24931 ENTREZGENE HomoloGene Group ID: 3621 ENTREZGENE Germonline: 2317 Pfam: V-set IPI KEGG Pathway: 04612 ENTREZGENE KEGG Pathway: 04514 ENTREZGENE KEGG Pathway: 04660 ENTREZGENE KEGG Pathway: 04640 ENTREZGENE KEGG Pathway: 05340 ENTREZGENE InterPro: Ig_V-set_sub. IPI InterPro: Ig_V-set. IPI InterPro: Ig-like_fold. IPI InterPro: Ig-like. IPI IPI: IPI00200585 IPI Ensembl Protein: ENSRNOP00000009392 IPI Gene3D-CATH: Ig-like_fold IPI Entrez Gene: Cd8b ENTREZGENE UniProt: Q6PCV0_RAT IPI UniProt: CD8B_RAT IPI Ensembl Genes: ENSRNOG00000007129 IPI RatMap: 34970 ENTREZGENE
Sequences	Nucleotide: CH473957 Get FASTA Search GEO Profiles Nucleotide: X04310 Get FASTA Search GEO Profiles Nucleotide: BC059127 Get FASTA Search GEO Profiles Nucleotide: NM_031539 Get FASTA Search GEO Profiles (View all 4 Nucleotide Accessions) Protein: NP_113727 Get FASTA Protein: EDL90988 Get FASTA Protein: CAA27850 Get FASTA Protein: P05541 Get FASTA Protein: Q6PCV0 Get FASTA Protein: AAH59127 Get FASTA (View all 6 Protein Accessions)
Clusters	UniGene: 10330
References
Curated References	5 references in RGD related to Cd8b
Other References	6 other references at PubMed related to Cd8b
Database Information
RGD ID	2317
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 26-SEP-08: Cd8b CD8b molecule Cd8b1 CD8b molecule APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 27-JUN-08: Cd8b1 CD8b molecule Cd8b CD8 antigen, beta chain APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 09-APR-03: Cd8b CD8 antigen, beta-chain APPROVED Symbol and Name updated 629477 11-MAR-03: Cd8b CD8 antigen, beta-chain Cd8b1 PROVISIONAL Data Merged 628472 07-AUG-02: Cd8b1 PROVISIONAL Symbol and Name status set to provisional 70820 10-JUN-02: Cd8b CD8 antigen, beta-chain APPROVED Symbol and Name status set to approved 70586