Cald1 (caldesmon 1) - Rat Genome Database

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Gene: Cald1 (caldesmon 1) Rattus norvegicus
Analyze
Symbol: Cald1
Name: caldesmon 1
RGD ID: 2256
Description: Enables actin binding activity. Involved in actin filament bundle assembly. Located in actin filament; dendritic spine; and neuronal cell body. Is active in glutamatergic synapse and postsynapse. Orthologous to human CALD1 (caldesmon 1); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CDM; h-caldesmon; l-Cad; L-caldesmon; non-muscle caldesmon
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bp116
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8464,232,906 - 64,414,085 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl464,233,171 - 64,414,085 (+)EnsemblGRCr8
mRatBN7.2463,265,781 - 63,446,938 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl463,265,942 - 63,446,932 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx468,224,218 - 68,404,830 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0464,139,917 - 64,320,566 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0462,542,329 - 62,722,959 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0462,103,948 - 62,291,375 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl462,220,736 - 62,291,489 (+)Ensemblrn6Rnor6.0
Rnor_5.0461,835,972 - 62,022,970 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4462,087,364 - 62,156,855 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera458,427,441 - 58,496,854 (+)NCBICelera
RGSC_v3.1462,363,493 - 62,432,985 (+)NCBI
RH 3.4 Map4396.8RGD
Cytogenetic Map4q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3,5-trinitro-1,3,5-triazinane  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dimethoxyphenol  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
alpha-pinene  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
buspirone  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
cisplatin  (EXP)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
DDT  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
fenamidone  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
furfural  (ISO)
geldanamycin  (ISO)
genistein  (EXP)
hydrogen cyanide  (ISO)
inulin  (ISO)
iron(III) nitrilotriacetate  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(II) chloride  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP,ISO)
methapyrilene  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
methylphenidate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nitrates  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium cyanide  (ISO)
potassium dichromate  (ISO)
propiconazole  (ISO)
raloxifene  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
sorafenib  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
tetrahydropalmatine  (ISO)
thioacetamide  (EXP)
toluene  (EXP)
topotecan  (EXP)
torcetrapib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
actin binding  (IBA,IDA,IEA,TAS)
calmodulin binding  (IEA)
myosin binding  (IBA,IEA)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Subcellular distribution of calponin and caldesmon in rat hippocampus. Agassandian C, etal., Brain Res. 2000 Dec 29;887(2):444-9.
2. Co-localization of caldesmon and calponin with cortical afferents, metabotropic glutamate and neurotrophic receptors in the lateral and central nuclei of the amygdala. Agassandian K and Cassell MD, Brain Res. 2008 Aug 21;1226:39-55. Epub 2008 Jun 11.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
6. ERK1/2-mediated phosphorylation of myometrial caldesmon during pregnancy and labor. Li Y, etal., Am J Physiol Regul Integr Comp Physiol 2003 Jan;284(1):R192-9.
7. Exploring the Immune Infiltration Landscape and M2 Macrophage-Related Biomarkers of Proliferative Diabetic Retinopathy. Meng Z, etal., Front Endocrinol (Lausanne). 2022 May 27;13:841813. doi: 10.3389/fendo.2022.841813. eCollection 2022.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. Caldesmon isoform associated with phenotypic modulation of mesangial cells. Okamoto K, etal., Exp Nephrol. 2000 Jan-Feb;8(1):20-7.
11. Distribution of caldesmon and of the acidic isoform of calponin in cultured cerebellar neurons and in different regions of the rat brain: an immunofluorescence and confocal microscopy study. Represa A, etal., Exp Cell Res. 1995 Dec;221(2):333-43.
12. GOA pipeline RGD automated data pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Characterization of the COOH terminus of non-muscle caldesmon mutants lacking mitosis-specific phosphorylation sites. Yamashiro S, etal., J Biol Chem 1995 Feb 24;270(8):4023-30.
15. Characterization of 83-kilodalton nonmuscle caldesmon from cultured rat cells: stimulation of actin binding of nonmuscle tropomyosin and periodic localization along microfilaments like tropomyosin. Yamashiro-Matsumura S and Matsumura F, J Cell Biol. 1988 Jun;106(6):1973-83.
Additional References at PubMed
PMID:1986309   PMID:2909534   PMID:12757606   PMID:16428310   PMID:16595550   PMID:16888241   PMID:17224451   PMID:17631293   PMID:19349302   PMID:19834610   PMID:19875849   PMID:21350330  
PMID:22158623   PMID:23077044   PMID:24036928   PMID:25468996   PMID:33450132   PMID:35352799  


Genomics

Comparative Map Data
Cald1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8464,232,906 - 64,414,085 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl464,233,171 - 64,414,085 (+)EnsemblGRCr8
mRatBN7.2463,265,781 - 63,446,938 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl463,265,942 - 63,446,932 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx468,224,218 - 68,404,830 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0464,139,917 - 64,320,566 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0462,542,329 - 62,722,959 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0462,103,948 - 62,291,375 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl462,220,736 - 62,291,489 (+)Ensemblrn6Rnor6.0
Rnor_5.0461,835,972 - 62,022,970 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4462,087,364 - 62,156,855 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera458,427,441 - 58,496,854 (+)NCBICelera
RGSC_v3.1462,363,493 - 62,432,985 (+)NCBI
RH 3.4 Map4396.8RGD
Cytogenetic Map4q22NCBI
CALD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387134,711,499 - 134,970,729 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7134,744,252 - 134,970,729 (+)Ensemblhg38GRCh38
GRCh377134,464,385 - 134,655,480 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367134,114,711 - 134,306,014 (+)NCBIBuild 36Build 36hg18NCBI36
Build 347133,921,425 - 134,112,725NCBI
Celera7129,201,597 - 129,392,887 (+)NCBICelera
Cytogenetic Map7q33NCBI
HuRef7128,766,283 - 128,958,067 (+)NCBIHuRef
CHM1_17134,398,049 - 134,589,415 (+)NCBICHM1_1
T2T-CHM13v2.07136,019,140 - 136,278,520 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27133,808,491 - 133,999,799 (+)NCBI
Cald1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39634,575,433 - 34,752,404 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl634,575,435 - 34,752,408 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38634,598,495 - 34,775,469 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl634,598,500 - 34,775,473 (+)Ensemblmm10GRCm38
MGSCv37634,659,444 - 34,725,469 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36634,639,637 - 34,704,252 (+)NCBIMGSCv36mm8
Celera634,709,193 - 34,775,837 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map615.07NCBI
Cald1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554947,578,028 - 7,765,758 (-)Ensembl
ChiLan1.0NW_0049554947,578,162 - 7,675,558 (-)NCBIChiLan1.0ChiLan1.0
CALD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26171,600,586 - 171,792,434 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1723,611,018 - 23,802,689 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07126,743,466 - 126,935,412 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17139,249,003 - 139,440,643 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7139,337,692 - 139,440,643 (+)EnsemblpanPan2panpan1.1
CALD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11613,087,419 - 13,279,648 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1613,084,109 - 13,279,384 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1614,099,621 - 14,291,557 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01613,068,418 - 13,257,206 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1613,068,504 - 13,256,992 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11613,510,057 - 13,701,885 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01612,609,385 - 12,797,864 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01612,748,692 - 12,937,241 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cald1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511820,736,003 - 20,913,613 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936579868,500 - 1,046,257 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936579868,681 - 1,046,198 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1814,267,959 - 14,486,726 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11814,267,955 - 14,486,641 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21815,075,913 - 15,194,572 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CALD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121103,435,238 - 103,671,901 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21103,469,975 - 103,672,699 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666072301,159 - 589,710 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cald1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476515,357,775 - 15,449,952 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476515,262,032 - 15,452,201 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cald1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16104,882,693 - 105,057,953 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cald1
1276 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:317
Count of miRNA genes:203
Interacting mature miRNAs:247
Transcripts:ENSRNOT00000041264
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)44049044275726188Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45807987582597589Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45808014680212111Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43726957782269577Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)46104105794638356Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)44047145375939996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42192515166925151Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46390045888813920Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45960331980216952Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat

Markers in Region
D4Rat256  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8464,402,411 - 64,402,629 (+)Marker Load Pipeline
mRatBN7.2463,435,262 - 63,435,482 (+)MAPPERmRatBN7.2
Rnor_6.0462,279,706 - 62,279,923NCBIRnor6.0
Rnor_5.0462,011,299 - 62,011,516UniSTSRnor5.0
RGSC_v3.4462,146,331 - 62,146,549RGDRGSC3.4
RGSC_v3.4462,146,332 - 62,146,549UniSTSRGSC3.4
Celera458,486,331 - 58,486,548UniSTS
RGSC_v3.1462,422,462 - 62,422,679RGD
RH 3.4 Map4393.4UniSTS
RH 3.4 Map4393.4RGD
RH 2.0 Map4424.7RGD
SHRSP x BN Map432.92RGD
Cytogenetic Map4q22UniSTS
RH94611  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2463,444,998 - 63,445,167 (+)MAPPERmRatBN7.2
Rnor_6.0462,289,440 - 62,289,608NCBIRnor6.0
Rnor_5.0462,021,033 - 62,021,201UniSTSRnor5.0
RGSC_v3.4462,156,066 - 62,156,234UniSTSRGSC3.4
Celera458,496,065 - 58,496,233UniSTS
RH 3.4 Map4396.8UniSTS
Cytogenetic Map4q22UniSTS
AI763841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2463,413,621 - 63,413,750 (+)MAPPERmRatBN7.2
Rnor_6.0462,258,066 - 62,258,194NCBIRnor6.0
Rnor_5.0461,989,671 - 61,989,799UniSTSRnor5.0
RGSC_v3.4462,124,419 - 62,124,547UniSTSRGSC3.4
Celera458,464,723 - 58,464,851UniSTS
RH 3.4 Map4399.22UniSTS
Cytogenetic Map4q22UniSTS
RH138325  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2463,391,117 - 63,391,302 (+)MAPPERmRatBN7.2
Rnor_6.0462,235,564 - 62,235,748NCBIRnor6.0
Rnor_5.0461,967,177 - 61,967,361UniSTSRnor5.0
RGSC_v3.4462,101,917 - 62,102,101UniSTSRGSC3.4
Celera458,442,000 - 58,442,184UniSTS
RH 3.4 Map4393.4UniSTS
Cytogenetic Map4q22UniSTS
RH141748  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2463,437,603 - 63,437,783 (+)MAPPERmRatBN7.2
Rnor_6.0462,282,045 - 62,282,224NCBIRnor6.0
Rnor_5.0462,013,638 - 62,013,817UniSTSRnor5.0
RGSC_v3.4462,148,671 - 62,148,850UniSTSRGSC3.4
Celera458,488,670 - 58,488,849UniSTS
RH 3.4 Map4375.2UniSTS
Cytogenetic Map4q22UniSTS
AI763841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2463,413,519 - 63,413,643 (+)MAPPERmRatBN7.2
Rnor_6.0462,257,964 - 62,258,087NCBIRnor6.0
Rnor_5.0461,989,569 - 61,989,692UniSTSRnor5.0
RGSC_v3.4462,124,317 - 62,124,440UniSTSRGSC3.4
Celera458,464,621 - 58,464,744UniSTS
RH 3.4 Map4399.22UniSTS
Cytogenetic Map4q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 87 59 6 351 187 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001398578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB049626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC103335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS158821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041264   ⟹   ENSRNOP00000043767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl464,343,440 - 64,414,085 (+)Ensembl
mRatBN7.2 Ensembl463,376,482 - 63,445,793 (+)Ensembl
Rnor_6.0 Ensembl462,221,011 - 62,290,229 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086377   ⟹   ENSRNOP00000068857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl464,233,171 - 64,414,082 (+)Ensembl
mRatBN7.2 Ensembl463,266,098 - 63,446,908 (+)Ensembl
Rnor_6.0 Ensembl462,220,736 - 62,291,489 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102454   ⟹   ENSRNOP00000087934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl464,233,171 - 64,407,890 (+)Ensembl
mRatBN7.2 Ensembl463,265,942 - 63,442,260 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112793   ⟹   ENSRNOP00000086440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl464,376,662 - 64,409,602 (+)Ensembl
mRatBN7.2 Ensembl463,409,514 - 63,442,455 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115054   ⟹   ENSRNOP00000093810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl464,343,715 - 64,414,085 (+)Ensembl
mRatBN7.2 Ensembl463,376,563 - 63,445,793 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115634   ⟹   ENSRNOP00000085217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl464,233,171 - 64,414,082 (+)Ensembl
mRatBN7.2 Ensembl463,266,114 - 63,446,932 (+)Ensembl
RefSeq Acc Id: NM_001398578   ⟹   NP_001385507
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,233,256 - 64,414,085 (+)NCBI
mRatBN7.2463,266,095 - 63,446,938 (+)NCBI
RefSeq Acc Id: NM_013146   ⟹   NP_037278
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,343,715 - 64,414,085 (+)NCBI
mRatBN7.2463,376,563 - 63,446,938 (+)NCBI
Rnor_6.0462,221,011 - 62,290,229 (+)NCBI
Rnor_5.0461,835,972 - 62,022,970 (+)NCBI
RGSC_v3.4462,087,364 - 62,156,855 (+)RGD
Celera458,427,441 - 58,496,854 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236260   ⟹   XP_006236322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,343,631 - 64,414,081 (+)NCBI
mRatBN7.2463,376,530 - 63,446,936 (+)NCBI
Rnor_6.0462,220,944 - 62,291,375 (+)NCBI
Rnor_5.0461,835,972 - 62,022,970 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236261   ⟹   XP_006236323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,232,906 - 64,414,081 (+)NCBI
mRatBN7.2463,265,781 - 63,446,936 (+)NCBI
Rnor_6.0462,104,120 - 62,291,375 (+)NCBI
Rnor_5.0461,835,972 - 62,022,970 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236262   ⟹   XP_006236324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,317,981 - 64,405,891 (+)NCBI
mRatBN7.2463,351,157 - 63,446,936 (+)NCBI
Rnor_6.0462,195,488 - 62,291,375 (+)NCBI
Rnor_5.0461,835,972 - 62,022,970 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592487   ⟹   XP_017447976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,233,003 - 64,405,891 (+)NCBI
mRatBN7.2463,265,895 - 63,446,936 (+)NCBI
Rnor_6.0462,103,948 - 62,291,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063285620   ⟹   XP_063141690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,343,631 - 64,405,891 (+)NCBI
RefSeq Acc Id: XM_063285621   ⟹   XP_063141691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,343,631 - 64,414,081 (+)NCBI
RefSeq Acc Id: XM_063285622   ⟹   XP_063141692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,343,631 - 64,414,081 (+)NCBI
RefSeq Acc Id: XM_063285623   ⟹   XP_063141693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,232,906 - 64,405,891 (+)NCBI
RefSeq Acc Id: XM_063285624   ⟹   XP_063141694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,233,003 - 64,405,891 (+)NCBI
RefSeq Acc Id: XM_063285625   ⟹   XP_063141695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,233,208 - 64,405,891 (+)NCBI
RefSeq Acc Id: XM_063285626   ⟹   XP_063141696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,317,981 - 64,405,891 (+)NCBI
RefSeq Acc Id: XM_063285627   ⟹   XP_063141697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,232,906 - 64,414,081 (+)NCBI
RefSeq Acc Id: XM_063285628   ⟹   XP_063141698
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,232,906 - 64,414,081 (+)NCBI
RefSeq Acc Id: XM_063285629   ⟹   XP_063141699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,343,631 - 64,405,891 (+)NCBI
RefSeq Acc Id: XM_063285630   ⟹   XP_063141700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,232,906 - 64,414,081 (+)NCBI
RefSeq Acc Id: XM_063285631   ⟹   XP_063141701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,232,926 - 64,414,081 (+)NCBI
RefSeq Acc Id: XM_063285632   ⟹   XP_063141702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,233,225 - 64,414,081 (+)NCBI
RefSeq Acc Id: XM_063285633   ⟹   XP_063141703
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,317,981 - 64,414,081 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001385507 (Get FASTA)   NCBI Sequence Viewer  
  NP_037278 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236322 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236323 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236324 (Get FASTA)   NCBI Sequence Viewer  
  XP_017447976 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141690 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141691 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141692 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141693 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141694 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141695 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141696 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141697 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141698 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141699 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141700 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141701 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141702 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141703 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB40836 (Get FASTA)   NCBI Sequence Viewer  
  CAJ29956 (Get FASTA)   NCBI Sequence Viewer  
  EDM15311 (Get FASTA)   NCBI Sequence Viewer  
  EDM15312 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000043767
  ENSRNOP00000085217
  ENSRNOP00000086440
  ENSRNOP00000087934
  ENSRNOP00000093810
GenBank Protein Q62736 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_037278   ⟸   NM_013146
- Peptide Label: isoform 2
- UniProtKB: Q62736 (UniProtKB/Swiss-Prot),   A6IEM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236323   ⟸   XM_006236261
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A6T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236324   ⟸   XM_006236262
- Peptide Label: isoform X10
- UniProtKB: A0A0G2JTV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236322   ⟸   XM_006236260
- Peptide Label: isoform X8
- UniProtKB: G3V9E3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447976   ⟸   XM_017592487
- Peptide Label: isoform X10
- UniProtKB: A0A0G2JTV2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000043767   ⟸   ENSRNOT00000041264
Ensembl Acc Id: ENSRNOP00000068857   ⟸   ENSRNOT00000086377
Ensembl Acc Id: ENSRNOP00000093810   ⟸   ENSRNOT00000115054
Ensembl Acc Id: ENSRNOP00000086440   ⟸   ENSRNOT00000112793
Ensembl Acc Id: ENSRNOP00000085217   ⟸   ENSRNOT00000115634
Ensembl Acc Id: ENSRNOP00000087934   ⟸   ENSRNOT00000102454
RefSeq Acc Id: NP_001385507   ⟸   NM_001398578
- Peptide Label: isoform 1
- UniProtKB: A6IEM4 (UniProtKB/TrEMBL),   A0A8I6A6T4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141697   ⟸   XM_063285627
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141698   ⟸   XM_063285628
- Peptide Label: isoform X6
- UniProtKB: A0A8I6GCL3 (UniProtKB/TrEMBL),   A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141700   ⟸   XM_063285630
- Peptide Label: isoform X9
- UniProtKB: A0A8I6GEY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141693   ⟸   XM_063285623
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141701   ⟸   XM_063285631
- Peptide Label: isoform X12
- UniProtKB: A6IEM4 (UniProtKB/TrEMBL),   A0A8I6A6T4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141694   ⟸   XM_063285624
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141695   ⟸   XM_063285625
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141702   ⟸   XM_063285632
- Peptide Label: isoform X12
- UniProtKB: A6IEM4 (UniProtKB/TrEMBL),   A0A8I6A6T4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141703   ⟸   XM_063285633
- Peptide Label: isoform X12
- UniProtKB: A6IEM4 (UniProtKB/TrEMBL),   A0A8I6A6T4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141696   ⟸   XM_063285626
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141691   ⟸   XM_063285621
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141692   ⟸   XM_063285622
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141690   ⟸   XM_063285620
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141699   ⟸   XM_063285629
- Peptide Label: isoform X7
- UniProtKB: G3V9E3 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62736-F1-model_v2 AlphaFold Q62736 1-531 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692955
Promoter ID:EPDNEW_R3479
Type:initiation region
Name:Cald1_1
Description:caldesmon 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0462,221,011 - 62,221,071EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2256 AgrOrtholog
BioCyc Gene G2FUF-45269 BioCyc
Ensembl Genes ENSRNOG00000010233 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000041264 ENTREZGENE
  ENSRNOT00000102454 ENTREZGENE
  ENSRNOT00000112793 ENTREZGENE
  ENSRNOT00000115054 ENTREZGENE
  ENSRNOT00000115634 ENTREZGENE
InterPro Caldesmon UniProtKB/Swiss-Prot
  Caldesmon_LSP UniProtKB/Swiss-Prot
KEGG Report rno:25687 UniProtKB/Swiss-Prot
NCBI Gene 25687 ENTREZGENE
PANTHER PTHR18949 UniProtKB/Swiss-Prot
  PTHR18949:SF0 UniProtKB/Swiss-Prot
Pfam Caldesmon UniProtKB/Swiss-Prot
PhenoGen Cald1 PhenoGen
PRINTS CALDESMON UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010233 RatGTEx
UniProt A0A0G2JTV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6T4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMH6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GCL3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GEY4 ENTREZGENE, UniProtKB/TrEMBL
  A6IEM4 ENTREZGENE, UniProtKB/TrEMBL
  A6IEM5 ENTREZGENE, UniProtKB/TrEMBL
  CALD1_RAT UniProtKB/Swiss-Prot
  G3V9E3 ENTREZGENE, UniProtKB/TrEMBL
  Q62736 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Cald1  Caldesmon 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression increased levels of h isoform during pregnancy 628554
gene_function actin binding protein 628554
gene_process increased levels suppress contractility of pregnant myometrium 628554
gene_process may play an active role in the regulation of myometrial contraction during pregnancy 628554
gene_process may contribute to a suppression of the contractility of pregnant myometrium 628554
gene_protein exists in two isoforms, high molecular weight (h) and low molecular weight (l) forms 628554
gene_regulation isoform specific phosphorylation by Erk1/2-mediated pathway may promote uterine contraction during labor 628554
gene_regulation phosphorylation is regulated by Mapk1 and 3 during pregnancy 628554