RGD Reference Report - Subcellular distribution of calponin and caldesmon in rat hippocampus. - Rat Genome Database

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Subcellular distribution of calponin and caldesmon in rat hippocampus.

Authors: Agassandian, C  Plantier, M  Fattoum, A  Represa, A  Der Terrossian, E 
Citation: Agassandian C, etal., Brain Res. 2000 Dec 29;887(2):444-9.
RGD ID: 2303067
Pubmed: PMID:11134639   (View Abstract at PubMed)

Caldesmon and calponin are two actin- and calmodulin-binding proteins involved in the 'actin-linked' regulation of smooth muscle and non-muscle Mg(2+)-actin-activated myosin II ATPase activity. In the present report we show that caldesmon and calponin are present in the post-synaptic side of symmetric synapses and accumulate in the post-synaptic densities of asymmetric synapses. Caldesmon- and calponin-immunoreactivities are also observed at the plasma membrane of the hippocampal neurones. Finally, while caldesmon seems strictly distributed to neurones, acidic calponin is present in both neurones and astrocytes.

Gene Ontology Annotations    Click to see Annotation Detail View

Cellular Component
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
dendritic spine  IDA 2303067; 2303067 RGD 
glutamatergic synapse is_active_inIDA 2303067; 2303067PMID:11134639SynGO 
postsynapse is_active_inIDA 2303067; 2303067PMID:11134639SynGO 

Objects Annotated

Genes (Rattus norvegicus)
Cald1  (caldesmon 1)
Cnn3  (calponin 3)


Additional Information