Bcan (brevican) - Rat Genome Database

Name: Bcan
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Bcan (brevican) Rattus norvegicus

Analyze

Symbol:

Bcan

Name:

brevican

RGD ID:

2194

Description:

Predicted to enable calcium ion binding activity; carbohydrate binding activity; and hyaluronic acid binding activity. Involved in cell-matrix adhesion; neurogenesis; and regulation of neuronal synaptic plasticity. Located in several cellular components, including main axon; perineuronal net; and synaptic membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and perisynaptic extracellular matrix. Used to study high grade glioma. Biomarker of high grade glioma and middle cerebral artery infarction. Orthologous to human BCAN (brevican); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ALPBRE; BEHAB; brain-enriched hyaluronan-binding protein; Brevican (brain specific proteoglycan in the aggrecan family); brevican core protein; brevican core protein-like; LOC100910284

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BCAN (brevican)	RGD	RGD
Mus musculus (house mouse):	Bcan (brevican)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Bcan (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BCAN (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BCAN (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bcan (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BCAN (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BCAN (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bcan (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TKTL2 (transketolase like 2)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Bcan (brevican)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	BCAN (brevican)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bcan (brevican)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	bcan	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	175,752,333 - 175,765,766 (-)	NCBI		GRCr8
mRatBN7.2	2	173,454,479 - 173,467,717 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	173,454,482 - 173,467,460 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	180,599,269 - 180,612,251 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	178,621,629 - 178,634,612 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	173,221,686 - 173,234,840 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	187,359,674 - 187,373,133 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	187,359,677 - 187,372,657 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	206,762,691 - 206,776,016 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	180,067,864 - 180,080,942 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	180,022,993 - 180,030,847 (-)	NCBI
Celera	2	167,401,907 - 167,414,841 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

Brain Hypoxia-Ischemia (IEP)

Charcot-Marie-Tooth disease type 2 (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

high grade glioma (IDA,IEP,ISO)

High Myopia (ISO)

immunodeficiency 42 (ISO)

MHC class II deficiency (ISO)

middle cerebral artery infarction (IEP)

Muscle Hypertonia (ISO)

parathyroid carcinoma (ISO)

Posthemorrhagic Hydrocephalus (ISO)

retinitis pigmentosa (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Spinal Cord Injuries (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP,ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

capsaicin (EXP)

carbon nanotube (ISO)

choline (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyhalothrin (EXP)

cypermethrin (EXP)

dibenz[a,h]anthracene (ISO)

dorsomorphin (ISO)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

glycidol (EXP)

L-methionine (ISO)

lead(0) (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

p-chloromercuribenzoic acid (ISO)

phenylmercury acetate (ISO)

pyrethrins (EXP)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trimellitic anhydride (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

cell-matrix adhesion (IDA)

central nervous system development (IBA)

glial cell differentiation (IBA,IEA)

gliogenesis (IEP)

hippocampus development (IEA,ISO)

neuron projection extension (IDA)

positive regulation of neuroblast proliferation (IBA,IEA)

regulation of neuronal synaptic plasticity (IEP)

skeletal system development (IBA,IEA)

synapse maturation (IEA,ISO)

Cellular Component

axon (IDA)

axon initial segment (IDA)

cell surface (IDA)

dendrite (IDA)

extracellular matrix (ISO)

extracellular region (IEA)

extracellular space (IBA,IDA,IEA)

GABA-ergic synapse (IDA)

glutamatergic synapse (IDA,IEA,ISO)

node of Ranvier (IDA)

perineuronal net (IBA,IDA,IEA,ISO)

perisynaptic extracellular matrix (IDA)

side of membrane (IEA)

synapse (IBA)

synaptic membrane (IDA)

Molecular Function

calcium ion binding (IEA)

carbohydrate binding (IEA)

hyaluronic acid binding (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw.	Ajmo JM, etal., J Neurochem. 2010 May;113(3):784-95. doi: 10.1111/j.1471-4159.2010.06647.x. Epub 2010 Feb 17.
2.	The effect of hypoxic-ischemic brain injury in perinatal rats on the abundance and proteolysis of brevican and NG2.	Aya-ay J, etal., Exp Neurol. 2005 May;193(1):149-62. doi: 10.1016/j.expneurol.2004.11.021.
3.	Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex.	Carmichael ST, etal., Exp Neurol. 2005 Jun;193(2):291-311.
4.	Decorin suppresses neurocan, brevican, phosphacan and NG2 expression and promotes axon growth across adult rat spinal cord injuries.	Davies JE, etal., Eur J Neurosci. 2004 Mar;19(5):1226-42.
5.	Composition of perineuronal net extracellular matrix in rat brain: a different disaccharide composition for the net-associated proteoglycans.	Deepa SS, etal., J Biol Chem. 2006 Jun 30;281(26):17789-800. Epub 2006 Apr 27.
6.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.	Immunohistochemical evidence for the brevican-tenascin-R interaction: colocalization in perineuronal nets suggests a physiological role for the interaction in the adult rat brain.	Hagihara K, etal., J Comp Neurol. 1999 Jul 26;410(2):256-64.
8.	Altered production and proteolytic processing of brevican by transforming growth factor beta in cultured astrocytes.	Hamel MG, etal., J Neurochem. 2005 Jun;93(6):1533-41.
9.	Neurofascin assembles a specialized extracellular matrix at the axon initial segment.	Hedstrom KL, etal., J Cell Biol. 2007 Aug 27;178(5):875-86. doi: 10.1083/jcb.200705119. Epub 2007 Aug 20.
10.	BEHAB, a new member of the proteoglycan tandem repeat family of hyaluronan-binding proteins that is restricted to the brain.	Jaworski DM, etal., J Cell Biol 1994 Apr;125(2):495-509.
11.	The CNS-specific hyaluronan-binding protein BEHAB is expressed in ventricular zones coincident with gliogenesis.	Jaworski DM, etal., J Neurosci. 1995 Feb;15(2):1352-62.
12.	Brevican-containing perineuronal nets of extracellular matrix in dissociated hippocampal primary cultures.	John N, etal., Mol Cell Neurosci. 2006 Apr;31(4):774-84. doi: 10.1016/j.mcn.2006.01.011. Epub 2006 Feb 28.
13.	The role of brevican in glioma: promoting tumor cell motility in vitro and in vivo.	Lu R, etal., BMC Cancer. 2012 Dec 19;12:607. doi: 10.1186/1471-2407-12-607.
14.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
15.	Carbohydrate-protein interactions between HNK-1-reactive sulfoglucuronyl glycolipids and the proteoglycan lectin domain mediate neuronal cell adhesion and neurite outgrowth.	Miura R, etal., J Neurochem. 2001 Jan;76(2):413-24.
16.	Alterations in protein regulators of neurodevelopment in the cerebrospinal fluid of infants with post-hemorrhagic hydrocephalus of prematurity.	Morales DM, etal., Mol Cell Proteomics. 2011 Dec 20.
17.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
18.	Brain enriched hyaluronan binding (BEHAB)/brevican increases aggressiveness of CNS-1 gliomas in Lewis rats.	Nutt CL, etal., Cancer Res. 2001 Oct 1;61(19):7056-9.
19.	GOA pipeline	RGD automated data pipeline
20.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
22.	Brevican, a chondroitin sulfate proteoglycan of rat brain, occurs as secreted and cell surface glycosylphosphatidylinositol-anchored isoforms.	Seidenbecher CI, etal., J Biol Chem 1995 Nov 10;270(45):27206-12.
23.	[Clinical consideration with special reference to autopsy cases of malignant tumor in the oral cavity, treated with Bleomycin (author's transl)]	Tanaka S, etal., Hiroshima Daigaku Shigaku Zasshi 1975;8(2):168-75.
24.	Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue.	Tang X, etal., J Neurosci Res 2003 Feb 1;71(3):427-44.
25.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
26.	Novel tumor-specific isoforms of BEHAB/brevican identified in human malignant gliomas.	Viapiano MS, etal., Cancer Res. 2005 Aug 1;65(15):6726-33. doi: 10.1158/0008-5472.CAN-05-0585.
27.	A novel membrane-associated glycovariant of BEHAB/brevican is up-regulated during rat brain development and in a rat model of invasive glioma.	Viapiano MS, etal., J Biol Chem. 2003 Aug 29;278(35):33239-47. doi: 10.1074/jbc.M303480200. Epub 2003 Jun 10.
28.	Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture.	Wohl SG, etal., Nat Commun. 2017 Nov 17;8(1):1603. doi: 10.1038/s41467-017-01624-y.
29.	cDNA cloning and the identification of an aggrecanase-like cleavage site in rat brevican.	Yamada H, etal., Biochem Biophys Res Commun 1995 Nov 22;216(3):957-63.

Additional References at PubMed

PMID:8889548	PMID:9294172	PMID:12370289	PMID:12379262	PMID:12477932	PMID:17972319	PMID:19141078	PMID:25052349	PMID:28712654	PMID:29476059

Genomics

Comparative Map Data

Bcan
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	175,752,333 - 175,765,766 (-)	NCBI		GRCr8
mRatBN7.2	2	173,454,479 - 173,467,717 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	173,454,482 - 173,467,460 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	180,599,269 - 180,612,251 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	178,621,629 - 178,634,612 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	173,221,686 - 173,234,840 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	187,359,674 - 187,373,133 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	187,359,677 - 187,372,657 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	206,762,691 - 206,776,016 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	180,067,864 - 180,080,942 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	180,022,993 - 180,030,847 (-)	NCBI
Celera	2	167,401,907 - 167,414,841 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

BCAN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	156,642,117 - 156,659,528 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	156,641,390 - 156,659,532 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	156,611,909 - 156,629,320 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	154,878,364 - 154,895,944 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	153,424,812 - 153,442,391	NCBI
Celera	1	129,682,549 - 129,700,133 (+)	NCBI		Celera
Cytogenetic Map	1	q23.1	NCBI
HuRef	1	127,969,333 - 127,986,922 (+)	NCBI		HuRef
CHM1_1	1	158,007,947 - 158,025,532 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	155,778,497 - 155,795,916 (+)	NCBI		T2T-CHM13v2.0

Bcan
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	87,894,839 - 87,908,458 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	87,894,838 - 87,907,537 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	87,987,531 - 88,002,175 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	87,987,531 - 88,000,230 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	87,791,453 - 87,804,278 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	88,073,458 - 88,086,157 (-)	NCBI		MGSCv36	mm8
Celera	3	88,024,909 - 88,037,731 (-)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	38.78	NCBI

Bcan
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	2,723,780 - 2,739,450 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	2,723,780 - 2,739,334 (+)	NCBI	ChiLan1.0	ChiLan1.0

BCAN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	93,185,075 - 93,204,399 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	92,919,574 - 92,938,939 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	131,985,310 - 132,003,068 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	135,808,783 - 135,826,344 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	135,808,783 - 135,826,344 (+)	Ensembl	panpan1.1		panPan2

BCAN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	41,313,578 - 41,330,178 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	41,313,579 - 41,330,178 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	40,800,863 - 40,817,472 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	41,176,717 - 41,193,313 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	41,176,718 - 41,248,421 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	40,958,653 - 40,975,224 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	41,011,623 - 41,028,215 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	41,295,291 - 41,311,883 (-)	NCBI		UU_Cfam_GSD_1.0

Bcan
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	26,785,957 - 26,798,152 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	5,816,359 - 5,828,126 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	5,816,196 - 5,828,531 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BCAN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	93,432,330 - 93,450,831 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	93,432,331 - 93,450,895 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	102,095,832 - 102,114,192 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BCAN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	7,203,546 - 7,221,108 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	7,203,378 - 7,220,973 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	6,499,085 - 6,516,895 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bcan
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	1,820,105 - 1,832,510 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	1,816,591 - 1,829,971 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Bcan
33 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	50
Count of miRNA genes:	43
Interacting mature miRNAs:	49
Transcripts:	ENSRNOT00000025496
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	182042367	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	43154682	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	43171017	184114403	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	114837527	185876470	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	114837527	185876470	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
6907363	Bp357	Blood pressure QTL 357	4.1	0.002	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	129540907	174540907	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	136916935	189599348	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	143657411	190602963	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	143657411	190602963	Rat
6903312	Bw112	Body weight QTL 112	3.2	0.0013	body mass (VT:0001259)	body weight (CMO:0000012)	2	143657569	184114274	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	144599348	189599348	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	147798556	192798556	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150341585	189039377	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
12879845	Cm89	Cardiac mass QTL 89		0.008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	152413072	175950118	Rat
12879846	Cm90	Cardiac mass QTL 90		0.011	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	2	152413072	175950118	Rat
12879847	Am4	Aortic mass QTL 4		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	152413072	175950118	Rat
11565180	Kidm56	Kidney mass QTL 56		0.003	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	152413072	175950118	Rat
11565181	Bw176	Body weight QTL 176		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	2	152413072	175950118	Rat
2301415	Cm67	Cardiac mass QTL 67		0.003	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	152413072	175950118	Rat
12879836	Kidm61	Kidney mass QTL 61		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	152413072	185122374	Rat
12879837	Am2	Aortic mass QTL 2		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	152413072	185122374	Rat
12879838	Cm86	Cardiac mass QTL 86		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	152413072	185122374	Rat
12879839	Cm85	Cardiac mass QTL 85		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	152413072	185122374	Rat
12879840	Bw179	Body weight QTL 179		0.005	body mass (VT:0001259)	body weight (CMO:0000012)	2	152413072	185122374	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	157142078	192625452	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168354880	185122374	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
61473	Bp19	Blood pressure QTL 19	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	172710921	175950118	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	172710921	184114403	Rat
7488904	Bp363	Blood pressure QTL 363		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	172982062	175950118	Rat

Markers in Region

RH138503

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	173,454,576 - 173,454,703 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	184,915,756 - 184,915,882	NCBI	Rnor6.0
Rnor_6.0	2	187,359,772 - 187,359,898	NCBI	Rnor6.0
Rnor_5.0	2	206,762,789 - 206,762,915	UniSTS	Rnor5.0
Rnor_5.0	2	204,306,829 - 204,306,955	UniSTS	Rnor5.0
RGSC_v3.4	2	180,067,962 - 180,068,088	UniSTS	RGSC3.4
Celera	2	167,402,005 - 167,402,131	UniSTS
RH 3.4 Map	2	1130.0	UniSTS
Cytogenetic Map	2	q34	UniSTS

UniSTS:224394

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	173,454,497 - 173,454,660 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	184,915,677 - 184,915,839	NCBI	Rnor6.0
Rnor_6.0	2	187,359,693 - 187,359,855	NCBI	Rnor6.0
Rnor_5.0	2	204,306,750 - 204,306,912	UniSTS	Rnor5.0
Rnor_5.0	2	206,762,710 - 206,762,872	UniSTS	Rnor5.0
RGSC_v3.4	2	180,067,883 - 180,068,045	UniSTS	RGSC3.4
Celera	2	167,401,926 - 167,402,088	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			1						54
Low		5	9		2				10		11	7
Below cutoff	2	23	23	17	16	17	8	8	4	4	18	4	8

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033665	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_012916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001836420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AI535159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC094307	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB577797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB784255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB810773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U37142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X79881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X86406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Z28366	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000025496 ⟹ ENSRNOP00000025496

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	173,454,482 - 173,467,460 (-)	Ensembl
Rnor_6.0 Ensembl	2	187,359,677 - 187,372,652 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000080610

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	184,915,247 - 184,917,462 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000083116 ⟹ ENSRNOP00000070660

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	187,366,297 - 187,372,657 (-)	Ensembl

RefSeq Acc Id:

NM_001033665 ⟹ NP_001028837

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,314 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,467,460 (-)	NCBI
Rnor_6.0	2	187,359,674 - 187,372,652 (-)	NCBI
Rnor_5.0	2	206,762,691 - 206,776,016 (-)	NCBI
RGSC_v3.4	2	180,067,864 - 180,080,942 (-)	RGD
Celera	2	167,401,907 - 167,414,841 (-)	RGD

Sequence:

show sequence

CCCGCGCAGAGAAGGGAGCGGGTCCCGTGACCGCGCAGAGCCCCCCACGGGGGCGGCAAAGGCC
GGGGACGGCGGGGAAGGCGGGGCGCGTGGGAAGAAAGGGGGTTTTGTGCGGCTCCCGGCGAGCT
GGCGCCCCCGTCTGCGTCCCGCGCGCCCGGCCCTGCTCGCGCCCGCGCATTGCGCCGCAGTCTC
GGCTGCGGCTGCGGGACGCGCGGTGTGTGGAGGGGACCTCACAAGTTCTTCCAAGTTTGCAGCA
TGATCCCATTGCTTCTGTCCCTGCTGGCAGCTCTGGTCCTGACCCAAGCCCCTGCAGCCCTCGC
TGATGACCTGAAAGAAGACAGCTCAGAGGATCGAGCCTTTCGGGTGCGCATCGGTGCCGCGCAG
CTGCGGGGTGTGCTGGGCGGTGCCCTGGCCATCCCATGCCACGTCCACCACCTGAGGCCGCCGC
CCAGCCGCCGGGCCGCGCCGGGCTTTCCCCGAGTCAAATGGACCTTCCTGTCCGGGGACCGGGA
GGTGGAGGTGCTGGTGGCGCGCGGGCTGCGCGTCAAGGTAAACGAAGCCTATCGGTTCCGCGTG
GCGCTGCCTGCCTACCCCGCATCGCTCACAGATGTGTCTTTAGTATTGAGCGAACTGCGGCCCA
ATGATTCCGGGGTCTATCGCTGCGAGGTCCAGCACGGTATCGACGACAGCAGTGATGCTGTGGA
AGTCAAGGTCAAAGGGGTCGTCTTCCTCTACCGAGAGGGCTCTGCCCGCTATGCTTTCTCCTTC
GCTGGAGCCCAGGAAGCCTGTGCTCGCATCGGAGCCCGAATTGCCACCCCTGAGCAGCTGTATG
CTGCCTACCTCGGCGGCTATGAACAGTGTGATGCTGGCTGGCTGTCCGACCAAACCGTGAGGTA
CCCCATCCAGAACCCACGAGAAGCCTGTTATGGAGACATGGATGGCTACCCTGGAGTGCGGAAT
TACGGAGTGGTGGGTCCTGATGATCTCTACGATGTCTACTGTTATGCCGAAGACCTAAATGGAG
AACTGTTCCTAGGTGCCCCTCCCGGCAAGCTGACGTGGGAGGAGGCTCGGGACTACTGTCTGGA
ACGCGGTGCTCAGATCGCTAGCACGGGCCAGCTATACGCGGCATGGAATGGCGGCTTGGACAGA
TGTAGCCCTGGCTGGCTGGCTGATGGCAGTGTGCGGTACCCCATCATCACGCCCAGCCAACGCT
GTGGGGGAGGCCTGCCAGGAGTCAAGACCCTCTTCCTCTTTCCCAACCAGACTGGCTTCCCCAG
CAAGCAGAACCGCTTCAATGTCTACTGCTTCCGAGACTCTGCCCATCCCTCTGCCTTCTCTGAG
GCCTCCAGCCCAGCCTCTGATGGACTAGAGGCCATTGTCACAGTGACAGAGAAGCTGGAGGAAC
TGCAGTTGCCTCAGGAAGCTGTGGAGAGCGAGTCTCGTGGGGCGATCTACTCCATCCCCATCAC
AGAAGATGGGGGAGGAGGAAGCTCTACCCCAGAAGACCCAGCAGAGGCCCCCAGGACTCCTCTA
GAATCAGAAACCCAATCCGTTGCACCACCTACCGGGTCCTCAGAAGAGGAAGGCGAAGCCCTGG
AGGAAGAAGAAAGATTCAAAGACACAGAGACTCCGAAGGAAGAGAAGGAGCAGGAGAACCTGTG
GGTGTGGCCCACGGAGCTCAGCAGCCCTCTCCCTACTGGCTTGGAAACAGAGCACTCACTCTCC
CAGGTGTCCCCACCAGCCCAGGCAGTTCTACAGCTGGGTGCATCACCTTCTCCCAGGCCTCCAA
GGGTCCATGGACCGCCTGCAGAGACTTTGCAACCCCCAAGGGAGGGAAGCCTCACATCTACTCC
AGATGGGGCAAGAGAAGTAGCGGGGGAAACTGGGAGCCCTGAGCTCTCTGGGGTTCCTCGAGAA
AGCGAGGAGGCAGGAAGCTCCAGCTTGGAGGATGGCCCTTCCCTCCTTCCAGCGACATGGGCCC
CTGTGGGTACCAGGGAGCTGGAGACCCCCTCAGAAGAGAAGTCTGGAAGAACTGTTCTGACAGG
CACATCAGTGCAGGCCCAGCCAGTGCTGCCCACCGACAGTGCCAGCCGAGGTGGAGTGGCTGTG
GCTCCCTCATCAGGTGACTGTATCCCCAGCCCCTGCCACAATGGTGGGACATGCTTGGAGGAGA
AGGAGGGTTTCCGCTGCCTCTGTTTGCCAGGCTATGGGGGGGACCTGTGCGATGTTGGCCTCCA
CTTCTGCAGCCCGGGCTGGGAGGCCTTCCAGGGTGCCTGCTACAAGCACTTTTCCACACGAAGG
AGTTGGGAGGAGGCAGAAAGCCAGTGCCGAGCGCTAGGGGCTCATCTGACCAGCATCTGCACCC
CTGAGGAGCAGGACTTTGTCAACGATCGATACAGGGAGTACCAGTGGATTGGGCTCAATGACAG
GACCATCGAGGGTGACTTCCTGTGGTCAGATGGTGCCCCTCTGCTCTATGAAAACTGGAACCCT
GGGCAGCCTGACAGCTACTTCCTGTCTGGGGAGAACTGTGTGGTCATGGTGTGGCATGACCAGG
GACAGTGGAGTGATGTACCCTGCAACTACCACCTATCCTACACCTGCAAGATGGGGCTTGTGTC
ATGTGGACCTCCACCACAGCTGCCCCTGGCTCAAATATTTGGTCGCCCTCGGCTGCGCTACGCG
GTGGACACTGTGCTTCGATATCGGTGCCGAGACGGGCTGGCCCAGCGCAACTTGCCGTTGATCC
GCTGCCAGGAGAATGGGCTTTGGGAGGCCCCTCAGATTTCTTGCGTGCCCCGAAGACCTGCCCG
TGCTCTCCGCTCAATGACCGCCCCAGAAGGACCACGGGGACAGCTCCCGAGGCAGAGGAAAGCA
CTGTTGACACCTCCCTCCAGTCTCTAGGGAACAGGCGTGGAAGACTACTGCCCCCACCAGGGCC
CTCTCACTTCAACTGCCTGTGCTCTTCCCTATGATAGGGGGTTGACAAGAGAGGGGTGGGACTG
GAATTCAGAGGACAAGCGCCCGAAGGGGTTTCTGGGAAACACTTGGGTGACTCCGCCCAACCTA
GACCCCGCCCCCTCATACAAGGGCCTCAGGTTTTACCCGGTAAGTCCCTAAGTGCCTCAACTGC
CTTCTGCTGTCAGCTGCCTCCTTGTTTCTCGATTTCTTTAGGGGACACTGTGCTACTCGTTCTT
AATTTTCAAAGGGTTTTTAGGATGGAGTACCAGCAAAACCAGGTGGAAATAAAGTTGTTTGAAC
CCAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_012916 ⟹ NP_037048

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,757,340 - 175,765,314 (-)	NCBI
mRatBN7.2	2	173,459,486 - 173,467,460 (-)	NCBI
Rnor_6.0	2	187,364,678 - 187,372,652 (-)	NCBI
Rnor_5.0	2	206,762,691 - 206,776,016 (-)	NCBI
RGSC_v3.4	2	180,067,864 - 180,080,942 (-)	RGD
Celera	2	167,406,914 - 167,414,841 (-)	NCBI

Sequence:

show sequence

CCCGCGCAGAGAAGGGAGCGGGTCCCGTGACCGCGCAGAGCCCCCCACGGGGGCGGCAAAGGCC
GGGGACGGCGGGGAAGGCGGGGCGCGTGGGAAGAAAGGGGGTTTTGTGCGGCTCCCGGCGAGCT
GGCGCCCCCGTCTGCGTCCCGCGCGCCCGGCCCTGCTCGCGCCCGCGCATTGCGCCGCAGTCTC
GGCTGCGGCTGCGGGACGCGCGGTGTGTGGAGGGGACCTCACAAGTTCTTCCAAGTTTGCAGCA
TGATCCCATTGCTTCTGTCCCTGCTGGCAGCTCTGGTCCTGACCCAAGCCCCTGCAGCCCTCGC
TGATGACCTGAAAGAAGACAGCTCAGAGGATCGAGCCTTTCGGGTGCGCATCGGTGCCGCGCAG
CTGCGGGGTGTGCTGGGCGGTGCCCTGGCCATCCCATGCCACGTCCACCACCTGAGGCCGCCGC
CCAGCCGCCGGGCCGCGCCGGGCTTTCCCCGAGTCAAATGGACCTTCCTGTCCGGGGACCGGGA
GGTGGAGGTGCTGGTGGCGCGCGGGCTGCGCGTCAAGGTAAACGAAGCCTATCGGTTCCGCGTG
GCGCTGCCTGCCTACCCCGCATCGCTCACAGATGTGTCTTTAGTATTGAGCGAACTGCGGCCCA
ATGATTCCGGGGTCTATCGCTGCGAGGTCCAGCACGGTATCGACGACAGCAGTGATGCTGTGGA
AGTCAAGGTCAAAGGGGTCGTCTTCCTCTACCGAGAGGGCTCTGCCCGCTATGCTTTCTCCTTC
GCTGGAGCCCAGGAAGCCTGTGCTCGCATCGGAGCCCGAATTGCCACCCCTGAGCAGCTGTATG
CTGCCTACCTCGGCGGCTATGAACAGTGTGATGCTGGCTGGCTGTCCGACCAAACCGTGAGGTA
CCCCATCCAGAACCCACGAGAAGCCTGTTATGGAGACATGGATGGCTACCCTGGAGTGCGGAAT
TACGGAGTGGTGGGTCCTGATGATCTCTACGATGTCTACTGTTATGCCGAAGACCTAAATGGAG
AACTGTTCCTAGGTGCCCCTCCCGGCAAGCTGACGTGGGAGGAGGCTCGGGACTACTGTCTGGA
ACGCGGTGCTCAGATCGCTAGCACGGGCCAGCTATACGCGGCATGGAATGGCGGCTTGGACAGA
TGTAGCCCTGGCTGGCTGGCTGATGGCAGTGTGCGGTACCCCATCATCACGCCCAGCCAACGCT
GTGGGGGAGGCCTGCCAGGAGTCAAGACCCTCTTCCTCTTTCCCAACCAGACTGGCTTCCCCAG
CAAGCAGAACCGCTTCAATGTCTACTGCTTCCGAGACTCTGCCCATCCCTCTGCCTTCTCTGAG
GCCTCCAGCCCAGCCTCTGATGGACTAGAGGCCATTGTCACAGTGACAGAGAAGCTGGAGGAAC
TGCAGTTGCCTCAGGAAGCTGTGGAGAGCGAGTCTCGTGGGGCGATCTACTCCATCCCCATCAC
AGAAGATGGGGGAGGAGGAAGCTCTACCCCAGAAGACCCAGCAGAGGCCCCCAGGACTCCTCTA
GAATCAGAAACCCAATCCGTTGCACCACCTACCGGGTCCTCAGAAGAGGAAGGCGAAGCCCTGG
AGGAAGAAGAAAGATTCAAAGACACAGAGACTCCGAAGGAAGAGAAGGAGCAGGAGAACCTGTG
GGTGTGGCCCACGGAGCTCAGCAGCCCTCTCCCTACTGGCTTGGAAACAGAGCACTCACTCTCC
CAGGTGTCCCCACCAGCCCAGGCAGTTCTACAGCTGGGTGCATCACCTTCTCCCAGGCCTCCAA
GGGTCCATGGACCGCCTGCAGAGACTTTGCAACCCCCAAGGGAGGGAAGCCTCACATCTACTCC
AGATGGGGCAAGAGAAGTAGCGGGGGAAACTGGGAGCCCTGAGCTCTCTGGGGTTCCTCGAGAA
AGCGAGGAGGCAGGAAGCTCCAGCTTGGAGGATGGCCCTTCCCTCCTTCCAGCGACATGGGCCC
CTGTGGGTACCAGGGAGCTGGAGACCCCCTCAGAAGAGAAGTCTGGAAGAACTGTTCTGACAGG
CACATCAGTGCAGGCCCAGCCAGTGCTGCCCACCGACAGTGCCAGCCGAGGTGGAGTGGCTGTG
GCTCCCTCATCAGGTAATTCTGCCGAAGGCTCGATGCCCGCCTTTCTCCTTTTCCTCCTCCTCC
AGCTCTGGGCCACCTGATCACGCTGGTCGGTCGGCCTTTAATCCACCTTCTCCCCGGACCCTCT
GGGCCTTTGCCCTCATTCCCTCTCCTGTCTCTCCCTGTGGATCTTTCTTCCATTCTGTCCCTTG
CGCCCCAGTTCTCTGATCCTCTGCTCCCCGGCCCTACCGCTGACCCCCACCACTGACCCTTGGG
CCCTCTGCTGTAGCTCCCATGTCACTGGCCACACAGGATGTCCTCAAGTCTCTTCCTGGTGCCC
TCACCAGCCTTCTCGACCCTTGAAGGCAGGCCTGCCATCTGCTGTCCCCTCCCTTGTGCCTTTT
GTTCCATCCCTTTAATCACCTCCCATGGATTCCAGGGACGCCTGAGAGACCATCCCTGCCCCTC
ACCTCTGGGGACCAGAATAGTCACCCCAAAGAGCCTTAAGCCACTACTTCTGTGAAGTATTTTT
TGACTGTTTCATGGAAAACAAGCCTTGGAAATAAATCTGTATTAAACTGCTTTGTACCCAGCTG
TTGACACCCAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039101784 ⟹ XP_038957712

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,763,771 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,465,898 (-)	NCBI

RefSeq Acc Id:

XM_039101786 ⟹ XP_038957714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,763,863 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,465,898 (-)	NCBI

RefSeq Acc Id:

XM_039101787 ⟹ XP_038957715

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,760 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,467,717 (-)	NCBI

RefSeq Acc Id:

XM_039101788 ⟹ XP_038957716

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,763 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,467,717 (-)	NCBI

RefSeq Acc Id:

XM_039101789 ⟹ XP_038957717

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,763,771 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,465,813 (-)	NCBI

RefSeq Acc Id:

XM_039101790 ⟹ XP_038957718

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,763 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,466,774 (-)	NCBI

RefSeq Acc Id:

XM_063281342 ⟹ XP_063137412

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,753,090 - 175,763,772 (-)	NCBI

RefSeq Acc Id:

XM_063281343 ⟹ XP_063137413

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,764,623 (-)	NCBI

RefSeq Acc Id:

XM_063281344 ⟹ XP_063137414

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,548 (-)	NCBI

RefSeq Acc Id:

XM_063281346 ⟹ XP_063137416

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,740 (-)	NCBI

RefSeq Acc Id:

XM_063281347 ⟹ XP_063137417

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,763,773 (-)	NCBI

RefSeq Acc Id:

XM_063281348 ⟹ XP_063137418

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,741 (-)	NCBI

RefSeq Acc Id:

XM_063281349 ⟹ XP_063137419

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,753,090 - 175,765,766 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001028837	(Get FASTA)	NCBI Sequence Viewer
	NP_037048	(Get FASTA)	NCBI Sequence Viewer
	XP_038957712	(Get FASTA)	NCBI Sequence Viewer
	XP_038957714	(Get FASTA)	NCBI Sequence Viewer
	XP_038957715	(Get FASTA)	NCBI Sequence Viewer
	XP_038957716	(Get FASTA)	NCBI Sequence Viewer
	XP_038957717	(Get FASTA)	NCBI Sequence Viewer
	XP_038957718	(Get FASTA)	NCBI Sequence Viewer
	XP_063137412	(Get FASTA)	NCBI Sequence Viewer
	XP_063137413	(Get FASTA)	NCBI Sequence Viewer
	XP_063137414	(Get FASTA)	NCBI Sequence Viewer
	XP_063137416	(Get FASTA)	NCBI Sequence Viewer
	XP_063137417	(Get FASTA)	NCBI Sequence Viewer
	XP_063137418	(Get FASTA)	NCBI Sequence Viewer
	XP_063137419	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA87847	(Get FASTA)	NCBI Sequence Viewer
	CAA56255	(Get FASTA)	NCBI Sequence Viewer
	CAA60160	(Get FASTA)	NCBI Sequence Viewer
	CAA82215	(Get FASTA)	NCBI Sequence Viewer
	EDM00746	(Get FASTA)	NCBI Sequence Viewer
	EDM00747	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000025496
	ENSRNOP00000025496.4
GenBank Protein	P55068	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001028837 ⟸ NM_001033665
- Peptide Label:	isoform 1 precursor
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot), G3V8G4 (UniProtKB/TrEMBL), A6J642 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIPLLLSLLAALVLTQAPAALADDLKEDSSEDRAFRVRIGAAQLRGVLGGALAIPCHVHHLRPP PSRRAAPGFPRVKWTFLSGDREVEVLVARGLRVKVNEAYRFRVALPAYPASLTDVSLVLSELRP NDSGVYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFAGAQEACARIGARIATPEQLY AAYLGGYEQCDAGWLSDQTVRYPIQNPREACYGDMDGYPGVRNYGVVGPDDLYDVYCYAEDLNG ELFLGAPPGKLTWEEARDYCLERGAQIASTGQLYAAWNGGLDRCSPGWLADGSVRYPIITPSQR CGGGLPGVKTLFLFPNQTGFPSKQNRFNVYCFRDSAHPSAFSEASSPASDGLEAIVTVTEKLEE LQLPQEAVESESRGAIYSIPITEDGGGGSSTPEDPAEAPRTPLESETQSVAPPTGSSEEEGEAL EEEERFKDTETPKEEKEQENLWVWPTELSSPLPTGLETEHSLSQVSPPAQAVLQLGASPSPRPP RVHGPPAETLQPPREGSLTSTPDGAREVAGETGSPELSGVPRESEEAGSSSLEDGPSLLPATWA PVGTRELETPSEEKSGRTVLTGTSVQAQPVLPTDSASRGGVAVAPSSGDCIPSPCHNGGTCLEE KEGFRCLCLPGYGGDLCDVGLHFCSPGWEAFQGACYKHFSTRRSWEEAESQCRALGAHLTSICT PEEQDFVNDRYREYQWIGLNDRTIEGDFLWSDGAPLLYENWNPGQPDSYFLSGENCVVMVWHDQ GQWSDVPCNYHLSYTCKMGLVSCGPPPQLPLAQIFGRPRLRYAVDTVLRYRCRDGLAQRNLPLI RCQENGLWEAPQISCVPRRPARALRSMTAPEGPRGQLPRQRKALLTPPSSL hide sequence

RefSeq Acc Id:	NP_037048 ⟸ NM_012916
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A6J643 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIPLLLSLLAALVLTQAPAALADDLKEDSSEDRAFRVRIGAAQLRGVLGGALAIPCHVHHLRPP PSRRAAPGFPRVKWTFLSGDREVEVLVARGLRVKVNEAYRFRVALPAYPASLTDVSLVLSELRP NDSGVYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFAGAQEACARIGARIATPEQLY AAYLGGYEQCDAGWLSDQTVRYPIQNPREACYGDMDGYPGVRNYGVVGPDDLYDVYCYAEDLNG ELFLGAPPGKLTWEEARDYCLERGAQIASTGQLYAAWNGGLDRCSPGWLADGSVRYPIITPSQR CGGGLPGVKTLFLFPNQTGFPSKQNRFNVYCFRDSAHPSAFSEASSPASDGLEAIVTVTEKLEE LQLPQEAVESESRGAIYSIPITEDGGGGSSTPEDPAEAPRTPLESETQSVAPPTGSSEEEGEAL EEEERFKDTETPKEEKEQENLWVWPTELSSPLPTGLETEHSLSQVSPPAQAVLQLGASPSPRPP RVHGPPAETLQPPREGSLTSTPDGAREVAGETGSPELSGVPRESEEAGSSSLEDGPSLLPATWA PVGTRELETPSEEKSGRTVLTGTSVQAQPVLPTDSASRGGVAVAPSSGNSAEGSMPAFLLFLLL QLWAT hide sequence

RefSeq Acc Id:

ENSRNOP00000070660 ⟸ ENSRNOT00000083116

RefSeq Acc Id:

ENSRNOP00000025496 ⟸ ENSRNOT00000025496

RefSeq Acc Id:	XP_038957715 ⟸ XM_039101787
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957716 ⟸ XM_039101788
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957718 ⟸ XM_039101790
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957714 ⟸ XM_039101786
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038957712 ⟸ XM_039101784
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957717 ⟸ XM_039101789
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063137418 ⟸ XM_063281348
- Peptide Label:	isoform X4
- UniProtKB:	A6J642 (UniProtKB/TrEMBL), G3V8G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137416 ⟸ XM_063281346
- Peptide Label:	isoform X4
- UniProtKB:	A6J642 (UniProtKB/TrEMBL), G3V8G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137414 ⟸ XM_063281344
- Peptide Label:	isoform X4
- UniProtKB:	A6J642 (UniProtKB/TrEMBL), G3V8G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137413 ⟸ XM_063281343
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063137417 ⟸ XM_063281347
- Peptide Label:	isoform X4
- UniProtKB:	A6J642 (UniProtKB/TrEMBL), G3V8G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137419 ⟸ XM_063281349
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063137412 ⟸ XM_063281342
- Peptide Label:	isoform X3

Protein Domains

C-type lectin EGF-like Ig-like Ig-like V-type Link Sushi

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P55068-F1-model_v2	AlphaFold	P55068	1-883	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2194	AgrOrtholog
BioCyc Gene	G2FUF-52523	BioCyc
Ensembl Genes	ENSRNOG00000018798	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000058727	Ensembl
Ensembl Transcript	ENSRNOT00000025496	ENTREZGENE
	ENSRNOT00000025496.7	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.10.100.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Complement Module, domain 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Laminin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	C-type_lectin-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C-type_lectin-like/link_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C-type_lectin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CTDL_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EGF-like_Ca-bd_dom	UniProtKB/TrEMBL
	EGF-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig/MHC_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Link_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sushi/SCR/CCP_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sushi_SCR_CCP_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25393	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	25393	ENTREZGENE
PANTHER	AGGRECAN/VERSICAN PROTEOGLYCAN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BREVICAN CORE PROTEIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	EGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lectin_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sushi	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Xlink	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Bcan	PhenoGen
PRINTS	LINKMODULE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	C_TYPE_LECTIN_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C_TYPE_LECTIN_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EGF_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EGF_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EGF_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IG_MHC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LINK_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LINK_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SUSHI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000018798	RatGTEx
	ENSRNOG00000058727	RatGTEx
SMART	CCP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CLECT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	IGv	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LINK	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF56436	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF57535	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC218890
UniProt	A6J642	ENTREZGENE, UniProtKB/TrEMBL
	A6J643	ENTREZGENE, UniProtKB/TrEMBL
	G3V8G4	ENTREZGENE, UniProtKB/TrEMBL
	P55068	ENTREZGENE, UniProtKB/Swiss-Prot
	Q62860	ENTREZGENE
	Q63040	ENTREZGENE
	Q63513	ENTREZGENE
UniProt Secondary	Q62860	UniProtKB/Swiss-Prot
	Q63040	UniProtKB/Swiss-Prot
	Q63513	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Bcan	brevican	LOC100910284	brevican core protein-like	Data merged from RGD:6499197	737654	PROVISIONAL
2012-07-05	LOC100910284	brevican core protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2002-06-10	Bcan	Brevican			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIA

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIA