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Gene: Bcan (brevican) Rattus norvegicus

Analyze

Symbol:

Bcan

Name:

brevican

RGD ID:

2194

Description:

Predicted to enable carbohydrate binding activity and hyaluronic acid binding activity. Involved in cell-matrix adhesion; neurogenesis; and regulation of neuronal synaptic plasticity. Located in several cellular components, including main axon; perineuronal net; and synaptic membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and perisynaptic extracellular matrix. Used to study high grade glioma. Biomarker of high grade glioma and middle cerebral artery infarction. Orthologous to human BCAN (brevican); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ALPBRE; BEHAB; brain-enriched hyaluronan-binding protein; Brevican (brain specific proteoglycan in the aggrecan family); brevican core protein; brevican core protein-like; LOC100910284

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BCAN (brevican)	RGD	RGD
Mus musculus (house mouse):	Bcan (brevican)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Bcan (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BCAN (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BCAN (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bcan (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BCAN (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BCAN (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bcan (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Bcan (brevican)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TKTL2 (transketolase like 2)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Bcan (brevican)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	BCAN (brevican)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bcan (brevican)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	bcan (brevican)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	bcan	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	175,752,333 - 175,765,766 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	175,752,336 - 175,765,314 (-)	Ensembl				GRCr8
mRatBN7.2	2	173,454,479 - 173,467,717 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	173,454,482 - 173,467,460 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	180,599,269 - 180,612,251 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	178,621,629 - 178,634,612 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	173,221,686 - 173,234,840 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	187,359,674 - 187,373,133 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	187,359,677 - 187,372,657 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	206,762,691 - 206,776,016 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	180,067,864 - 180,080,942 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	167,401,907 - 167,414,841 (-)	NCBI		Celera
RGSC_v3.1	2	180,022,993 - 180,030,847 (-)	NCBI
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

Brain Hypoxia-Ischemia (IEP)

high grade glioma (IDA,IEP,ISO)

middle cerebral artery infarction (IEP)

Muscle Hypertonia (ISO)

Posthemorrhagic Hydrocephalus (ISO)

retinitis pigmentosa (ISO)

Spinal Cord Injuries (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP,ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

capsaicin (EXP)

carbon nanotube (ISO)

choline (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyhalothrin (EXP)

cypermethrin (EXP)

D-glucose (ISO)

dibenz[a,h]anthracene (ISO)

dorsomorphin (ISO)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

glucose (ISO)

glycidol (EXP)

L-methionine (ISO)

lead(0) (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

okadaic acid (ISO)

p-chloromercuribenzoic acid (ISO)

phenylmercury acetate (ISO)

pyrethrins (EXP)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trimellitic anhydride (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

cell-matrix adhesion (IDA)

central nervous system development (IBA)

gliogenesis (IEA,IEP)

hippocampus development (ISO)

neuron projection extension (IDA)

neuron projection morphogenesis (IEA)

regulation of neuronal synaptic plasticity (IEP)

skeletal system development (IBA)

synapse maturation (IEA,ISO)

Cellular Component

axon (IDA)

axon initial segment (IDA)

cell surface (IDA)

dendrite (IDA)

extracellular matrix (IEA,ISO)

extracellular region (IEA)

extracellular space (IBA,IDA)

GABA-ergic synapse (IDA)

glutamatergic synapse (IDA,IEA,ISO)

membrane (IEA)

node of Ranvier (IDA)

perineuronal net (IBA,IDA,IEA,ISO)

perisynaptic extracellular matrix (IDA)

plasma membrane (IEA)

side of membrane (IEA)

synapse (IBA)

synaptic membrane (IDA)

Molecular Function

calcium ion binding (IEA)

carbohydrate binding (IEA)

hyaluronic acid binding (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw.	Ajmo JM, etal., J Neurochem. 2010 May;113(3):784-95. doi: 10.1111/j.1471-4159.2010.06647.x. Epub 2010 Feb 17.
2.	The effect of hypoxic-ischemic brain injury in perinatal rats on the abundance and proteolysis of brevican and NG2.	Aya-ay J, etal., Exp Neurol. 2005 May;193(1):149-62. doi: 10.1016/j.expneurol.2004.11.021.
3.	Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex.	Carmichael ST, etal., Exp Neurol. 2005 Jun;193(2):291-311.
4.	Decorin suppresses neurocan, brevican, phosphacan and NG2 expression and promotes axon growth across adult rat spinal cord injuries.	Davies JE, etal., Eur J Neurosci. 2004 Mar;19(5):1226-42.
5.	Composition of perineuronal net extracellular matrix in rat brain: a different disaccharide composition for the net-associated proteoglycans.	Deepa SS, etal., J Biol Chem. 2006 Jun 30;281(26):17789-800. Epub 2006 Apr 27.
6.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.	Immunohistochemical evidence for the brevican-tenascin-R interaction: colocalization in perineuronal nets suggests a physiological role for the interaction in the adult rat brain.	Hagihara K, etal., J Comp Neurol. 1999 Jul 26;410(2):256-64.
8.	Altered production and proteolytic processing of brevican by transforming growth factor beta in cultured astrocytes.	Hamel MG, etal., J Neurochem. 2005 Jun;93(6):1533-41.
9.	Neurofascin assembles a specialized extracellular matrix at the axon initial segment.	Hedstrom KL, etal., J Cell Biol. 2007 Aug 27;178(5):875-86. doi: 10.1083/jcb.200705119. Epub 2007 Aug 20.
10.	BEHAB, a new member of the proteoglycan tandem repeat family of hyaluronan-binding proteins that is restricted to the brain.	Jaworski DM, etal., J Cell Biol 1994 Apr;125(2):495-509.
11.	The CNS-specific hyaluronan-binding protein BEHAB is expressed in ventricular zones coincident with gliogenesis.	Jaworski DM, etal., J Neurosci. 1995 Feb;15(2):1352-62.
12.	Brevican-containing perineuronal nets of extracellular matrix in dissociated hippocampal primary cultures.	John N, etal., Mol Cell Neurosci. 2006 Apr;31(4):774-84. doi: 10.1016/j.mcn.2006.01.011. Epub 2006 Feb 28.
13.	The role of brevican in glioma: promoting tumor cell motility in vitro and in vivo.	Lu R, etal., BMC Cancer. 2012 Dec 19;12:607. doi: 10.1186/1471-2407-12-607.
14.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
15.	Carbohydrate-protein interactions between HNK-1-reactive sulfoglucuronyl glycolipids and the proteoglycan lectin domain mediate neuronal cell adhesion and neurite outgrowth.	Miura R, etal., J Neurochem. 2001 Jan;76(2):413-24.
16.	Alterations in protein regulators of neurodevelopment in the cerebrospinal fluid of infants with post-hemorrhagic hydrocephalus of prematurity.	Morales DM, etal., Mol Cell Proteomics. 2011 Dec 20.
17.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
18.	Brain enriched hyaluronan binding (BEHAB)/brevican increases aggressiveness of CNS-1 gliomas in Lewis rats.	Nutt CL, etal., Cancer Res. 2001 Oct 1;61(19):7056-9.
19.	GOA pipeline	RGD automated data pipeline
20.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
22.	Brevican, a chondroitin sulfate proteoglycan of rat brain, occurs as secreted and cell surface glycosylphosphatidylinositol-anchored isoforms.	Seidenbecher CI, etal., J Biol Chem 1995 Nov 10;270(45):27206-12.
23.	[Clinical consideration with special reference to autopsy cases of malignant tumor in the oral cavity, treated with Bleomycin (author's transl)]	Tanaka S, etal., Hiroshima Daigaku Shigaku Zasshi 1975;8(2):168-75.
24.	Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue.	Tang X, etal., J Neurosci Res 2003 Feb 1;71(3):427-44.
25.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
26.	Novel tumor-specific isoforms of BEHAB/brevican identified in human malignant gliomas.	Viapiano MS, etal., Cancer Res. 2005 Aug 1;65(15):6726-33. doi: 10.1158/0008-5472.CAN-05-0585.
27.	A novel membrane-associated glycovariant of BEHAB/brevican is up-regulated during rat brain development and in a rat model of invasive glioma.	Viapiano MS, etal., J Biol Chem. 2003 Aug 29;278(35):33239-47. doi: 10.1074/jbc.M303480200. Epub 2003 Jun 10.
28.	Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture.	Wohl SG, etal., Nat Commun. 2017 Nov 17;8(1):1603. doi: 10.1038/s41467-017-01624-y.
29.	cDNA cloning and the identification of an aggrecanase-like cleavage site in rat brevican.	Yamada H, etal., Biochem Biophys Res Commun 1995 Nov 22;216(3):957-63.

Additional References at PubMed

PMID:8889548	PMID:9294172	PMID:12370289	PMID:12379262	PMID:12477932	PMID:17972319	PMID:19141078	PMID:25052349	PMID:28712654	PMID:29476059

Genomics

Comparative Map Data

Bcan
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	175,752,333 - 175,765,766 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	175,752,336 - 175,765,314 (-)	Ensembl				GRCr8
mRatBN7.2	2	173,454,479 - 173,467,717 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	173,454,482 - 173,467,460 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	180,599,269 - 180,612,251 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	178,621,629 - 178,634,612 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	173,221,686 - 173,234,840 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	187,359,674 - 187,373,133 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	187,359,677 - 187,372,657 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	206,762,691 - 206,776,016 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	180,067,864 - 180,080,942 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	167,401,907 - 167,414,841 (-)	NCBI		Celera
RGSC_v3.1	2	180,022,993 - 180,030,847 (-)	NCBI
Cytogenetic Map	2	q34	NCBI

BCAN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	156,642,117 - 156,659,528 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	156,641,390 - 156,659,532 (+)	Ensembl			hg38	GRCh38
GRCh37	1	156,611,909 - 156,629,320 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	154,878,364 - 154,895,944 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	153,424,812 - 153,442,391	NCBI
Celera	1	129,682,549 - 129,700,133 (+)	NCBI		Celera
Cytogenetic Map	1	q23.1	NCBI
HuRef	1	127,969,333 - 127,986,922 (+)	NCBI		HuRef
CHM1_1	1	158,007,947 - 158,025,532 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	155,778,497 - 155,795,916 (+)	NCBI		T2T-CHM13v2.0

Bcan
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	87,894,839 - 87,908,458 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	87,894,838 - 87,907,537 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	87,987,531 - 88,002,175 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	87,987,531 - 88,000,230 (-)	Ensembl			mm10	GRCm38
MGSCv37	3	87,791,453 - 87,804,278 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	88,073,458 - 88,086,157 (-)	NCBI		MGSCv36	mm8
Celera	3	88,024,909 - 88,037,731 (-)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	38.78	NCBI

Bcan
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	2,723,780 - 2,739,450 (+)	Ensembl
ChiLan1.0	NW_004955545	2,723,780 - 2,739,334 (+)	NCBI	ChiLan1.0	ChiLan1.0

BCAN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	93,185,075 - 93,204,399 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	92,919,574 - 92,938,939 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	131,985,310 - 132,003,068 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	135,808,783 - 135,826,344 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	135,808,783 - 135,826,344 (+)	Ensembl			panPan2	panpan1.1

BCAN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	41,313,578 - 41,330,178 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	41,313,579 - 41,330,178 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	40,800,863 - 40,817,472 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	41,176,717 - 41,193,313 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	41,176,718 - 41,248,421 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	40,958,653 - 40,975,224 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	41,011,623 - 41,028,215 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	41,295,291 - 41,311,883 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Bcan
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	26,785,957 - 26,798,152 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	5,816,359 - 5,828,126 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	5,816,196 - 5,828,531 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BCAN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	93,432,330 - 93,450,831 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	93,432,331 - 93,450,895 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	102,095,832 - 102,114,192 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BCAN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	7,203,546 - 7,221,108 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	7,203,378 - 7,220,973 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	6,499,085 - 6,516,895 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bcan
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	1,820,105 - 1,832,510 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624885	1,816,591 - 1,829,971 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Bcan
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	65,557,849 - 65,570,665 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Bcan
67 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	50
Count of miRNA genes:	43
Interacting mature miRNAs:	49
Transcripts:	ENSRNOT00000025496
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	163997722	225110681	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	169358774	214358774	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	138595962	205135428	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	124537199	209621565	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
12879836	Kidm61	Kidney mass QTL 61		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	154723085	199723085	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	145807215	190807215	Rat
12879837	Am2	Aortic mass QTL 2		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	154723085	199723085	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	205135267	Rat
10043139	Iddm55	Insulin dependent diabetes mellitus QTL 55	3.1	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	150313808	195313808	Rat
12879838	Cm86	Cardiac mass QTL 86		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	154723085	199723085	Rat
12879839	Cm85	Cardiac mass QTL 85		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	154723085	199723085	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170652929	215652929	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	220931218	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	171994826	205135428	Rat
61473	Bp19	Blood pressure QTL 19	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	178247591	Rat
12879845	Cm89	Cardiac mass QTL 89		0.008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	154723085	178247591	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	143565208	188565208	Rat
12879846	Cm90	Cardiac mass QTL 90		0.011	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	2	154723085	178247591	Rat
12879847	Am4	Aortic mass QTL 4		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	154723085	178247591	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
12879840	Bw179	Body weight QTL 179		0.005	body mass (VT:0001259)	body weight (CMO:0000012)	2	154723085	199723085	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	139067258	192287892	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	159440760	195313808	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	144882354	205135428	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
1357991	Ael2	Aortic elastin QTL 2	4.2	0.000071	aorta elastin amount (VT:0003905)	aortic elastin	2	169227906	214227906	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	139067258	184067258	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	159440760	228950743	Rat
2301415	Cm67	Cardiac mass QTL 67		0.003	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	154723085	178247591	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	143746578	205135428	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
11565180	Kidm56	Kidney mass QTL 56		0.003	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	154723085	178247591	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150096616	195096616	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
11565181	Bw176	Body weight QTL 176		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	2	154723085	178247591	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	145306936	212705578	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	113746222	205135428	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	147287892	192287892	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	223841096	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	117415288	205135428	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150096616	195096616	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	220008837	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	165453811	210453811	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	163253030	208253030	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat
7488904	Bp363	Blood pressure QTL 363		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	175279960	178247591	Rat

Markers in Region

RH138503

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	173,454,576 - 173,454,703 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	184,915,756 - 184,915,882	NCBI	Rnor6.0
Rnor_6.0	2	187,359,772 - 187,359,898	NCBI	Rnor6.0
Rnor_5.0	2	206,762,789 - 206,762,915	UniSTS	Rnor5.0
Rnor_5.0	2	204,306,829 - 204,306,955	UniSTS	Rnor5.0
RGSC_v3.4	2	180,067,962 - 180,068,088	UniSTS	RGSC3.4
Celera	2	167,402,005 - 167,402,131	UniSTS
RH 3.4 Map	2	1130.0	UniSTS
Cytogenetic Map	2	q34	UniSTS

UniSTS:224394

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	173,454,497 - 173,454,660 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	184,915,677 - 184,915,839	NCBI	Rnor6.0
Rnor_6.0	2	187,359,693 - 187,359,855	NCBI	Rnor6.0
Rnor_5.0	2	204,306,750 - 204,306,912	UniSTS	Rnor5.0
Rnor_5.0	2	206,762,710 - 206,762,872	UniSTS	Rnor5.0
RGSC_v3.4	2	180,067,883 - 180,068,045	UniSTS	RGSC3.4
Celera	2	167,401,926 - 167,402,088	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
8	8	51	149	65	64	33	36	33	5	184	111	7	131	24	77	31	13	13

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033665	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_012916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001836420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AI535159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC094307	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB577797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB784255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB810773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U37142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X79881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X86406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Z28366	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000025496 ⟹ ENSRNOP00000025496

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	175,752,336 - 175,765,314 (-)	Ensembl
mRatBN7.2 Ensembl	2	173,454,482 - 173,467,460 (-)	Ensembl
Rnor_6.0 Ensembl	2	187,359,677 - 187,372,652 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000080610

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	184,915,247 - 184,917,462 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083116 ⟹ ENSRNOP00000070660

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	187,366,297 - 187,372,657 (-)	Ensembl

RefSeq Acc Id:

NM_001033665 ⟹ NP_001028837

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,314 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,467,460 (-)	NCBI
Rnor_6.0	2	187,359,674 - 187,372,652 (-)	NCBI
Rnor_5.0	2	206,762,691 - 206,776,016 (-)	NCBI
RGSC_v3.4	2	180,067,864 - 180,080,942 (-)	RGD
Celera	2	167,401,907 - 167,414,841 (-)	RGD

Sequence:

show sequence

CCCGCGCAGAGAAGGGAGCGGGTCCCGTGACCGCGCAGAGCCCCCCACGGGGGCGGCAAAGGCC
GGGGACGGCGGGGAAGGCGGGGCGCGTGGGAAGAAAGGGGGTTTTGTGCGGCTCCCGGCGAGCT
GGCGCCCCCGTCTGCGTCCCGCGCGCCCGGCCCTGCTCGCGCCCGCGCATTGCGCCGCAGTCTC
GGCTGCGGCTGCGGGACGCGCGGTGTGTGGAGGGGACCTCACAAGTTCTTCCAAGTTTGCAGCA
TGATCCCATTGCTTCTGTCCCTGCTGGCAGCTCTGGTCCTGACCCAAGCCCCTGCAGCCCTCGC
TGATGACCTGAAAGAAGACAGCTCAGAGGATCGAGCCTTTCGGGTGCGCATCGGTGCCGCGCAG
CTGCGGGGTGTGCTGGGCGGTGCCCTGGCCATCCCATGCCACGTCCACCACCTGAGGCCGCCGC
CCAGCCGCCGGGCCGCGCCGGGCTTTCCCCGAGTCAAATGGACCTTCCTGTCCGGGGACCGGGA
GGTGGAGGTGCTGGTGGCGCGCGGGCTGCGCGTCAAGGTAAACGAAGCCTATCGGTTCCGCGTG
GCGCTGCCTGCCTACCCCGCATCGCTCACAGATGTGTCTTTAGTATTGAGCGAACTGCGGCCCA
ATGATTCCGGGGTCTATCGCTGCGAGGTCCAGCACGGTATCGACGACAGCAGTGATGCTGTGGA
AGTCAAGGTCAAAGGGGTCGTCTTCCTCTACCGAGAGGGCTCTGCCCGCTATGCTTTCTCCTTC
GCTGGAGCCCAGGAAGCCTGTGCTCGCATCGGAGCCCGAATTGCCACCCCTGAGCAGCTGTATG
CTGCCTACCTCGGCGGCTATGAACAGTGTGATGCTGGCTGGCTGTCCGACCAAACCGTGAGGTA
CCCCATCCAGAACCCACGAGAAGCCTGTTATGGAGACATGGATGGCTACCCTGGAGTGCGGAAT
TACGGAGTGGTGGGTCCTGATGATCTCTACGATGTCTACTGTTATGCCGAAGACCTAAATGGAG
AACTGTTCCTAGGTGCCCCTCCCGGCAAGCTGACGTGGGAGGAGGCTCGGGACTACTGTCTGGA
ACGCGGTGCTCAGATCGCTAGCACGGGCCAGCTATACGCGGCATGGAATGGCGGCTTGGACAGA
TGTAGCCCTGGCTGGCTGGCTGATGGCAGTGTGCGGTACCCCATCATCACGCCCAGCCAACGCT
GTGGGGGAGGCCTGCCAGGAGTCAAGACCCTCTTCCTCTTTCCCAACCAGACTGGCTTCCCCAG
CAAGCAGAACCGCTTCAATGTCTACTGCTTCCGAGACTCTGCCCATCCCTCTGCCTTCTCTGAG
GCCTCCAGCCCAGCCTCTGATGGACTAGAGGCCATTGTCACAGTGACAGAGAAGCTGGAGGAAC
TGCAGTTGCCTCAGGAAGCTGTGGAGAGCGAGTCTCGTGGGGCGATCTACTCCATCCCCATCAC
AGAAGATGGGGGAGGAGGAAGCTCTACCCCAGAAGACCCAGCAGAGGCCCCCAGGACTCCTCTA
GAATCAGAAACCCAATCCGTTGCACCACCTACCGGGTCCTCAGAAGAGGAAGGCGAAGCCCTGG
AGGAAGAAGAAAGATTCAAAGACACAGAGACTCCGAAGGAAGAGAAGGAGCAGGAGAACCTGTG
GGTGTGGCCCACGGAGCTCAGCAGCCCTCTCCCTACTGGCTTGGAAACAGAGCACTCACTCTCC
CAGGTGTCCCCACCAGCCCAGGCAGTTCTACAGCTGGGTGCATCACCTTCTCCCAGGCCTCCAA
GGGTCCATGGACCGCCTGCAGAGACTTTGCAACCCCCAAGGGAGGGAAGCCTCACATCTACTCC
AGATGGGGCAAGAGAAGTAGCGGGGGAAACTGGGAGCCCTGAGCTCTCTGGGGTTCCTCGAGAA
AGCGAGGAGGCAGGAAGCTCCAGCTTGGAGGATGGCCCTTCCCTCCTTCCAGCGACATGGGCCC
CTGTGGGTACCAGGGAGCTGGAGACCCCCTCAGAAGAGAAGTCTGGAAGAACTGTTCTGACAGG
CACATCAGTGCAGGCCCAGCCAGTGCTGCCCACCGACAGTGCCAGCCGAGGTGGAGTGGCTGTG
GCTCCCTCATCAGGTGACTGTATCCCCAGCCCCTGCCACAATGGTGGGACATGCTTGGAGGAGA
AGGAGGGTTTCCGCTGCCTCTGTTTGCCAGGCTATGGGGGGGACCTGTGCGATGTTGGCCTCCA
CTTCTGCAGCCCGGGCTGGGAGGCCTTCCAGGGTGCCTGCTACAAGCACTTTTCCACACGAAGG
AGTTGGGAGGAGGCAGAAAGCCAGTGCCGAGCGCTAGGGGCTCATCTGACCAGCATCTGCACCC
CTGAGGAGCAGGACTTTGTCAACGATCGATACAGGGAGTACCAGTGGATTGGGCTCAATGACAG
GACCATCGAGGGTGACTTCCTGTGGTCAGATGGTGCCCCTCTGCTCTATGAAAACTGGAACCCT
GGGCAGCCTGACAGCTACTTCCTGTCTGGGGAGAACTGTGTGGTCATGGTGTGGCATGACCAGG
GACAGTGGAGTGATGTACCCTGCAACTACCACCTATCCTACACCTGCAAGATGGGGCTTGTGTC
ATGTGGACCTCCACCACAGCTGCCCCTGGCTCAAATATTTGGTCGCCCTCGGCTGCGCTACGCG
GTGGACACTGTGCTTCGATATCGGTGCCGAGACGGGCTGGCCCAGCGCAACTTGCCGTTGATCC
GCTGCCAGGAGAATGGGCTTTGGGAGGCCCCTCAGATTTCTTGCGTGCCCCGAAGACCTGCCCG
TGCTCTCCGCTCAATGACCGCCCCAGAAGGACCACGGGGACAGCTCCCGAGGCAGAGGAAAGCA
CTGTTGACACCTCCCTCCAGTCTCTAGGGAACAGGCGTGGAAGACTACTGCCCCCACCAGGGCC
CTCTCACTTCAACTGCCTGTGCTCTTCCCTATGATAGGGGGTTGACAAGAGAGGGGTGGGACTG
GAATTCAGAGGACAAGCGCCCGAAGGGGTTTCTGGGAAACACTTGGGTGACTCCGCCCAACCTA
GACCCCGCCCCCTCATACAAGGGCCTCAGGTTTTACCCGGTAAGTCCCTAAGTGCCTCAACTGC
CTTCTGCTGTCAGCTGCCTCCTTGTTTCTCGATTTCTTTAGGGGACACTGTGCTACTCGTTCTT
AATTTTCAAAGGGTTTTTAGGATGGAGTACCAGCAAAACCAGGTGGAAATAAAGTTGTTTGAAC
CCAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_012916 ⟹ NP_037048

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,757,340 - 175,765,314 (-)	NCBI
mRatBN7.2	2	173,459,486 - 173,467,460 (-)	NCBI
Rnor_6.0	2	187,364,678 - 187,372,652 (-)	NCBI
Rnor_5.0	2	206,762,691 - 206,776,016 (-)	NCBI
RGSC_v3.4	2	180,067,864 - 180,080,942 (-)	RGD
Celera	2	167,406,914 - 167,414,841 (-)	NCBI

Sequence:

show sequence

CCCGCGCAGAGAAGGGAGCGGGTCCCGTGACCGCGCAGAGCCCCCCACGGGGGCGGCAAAGGCC
GGGGACGGCGGGGAAGGCGGGGCGCGTGGGAAGAAAGGGGGTTTTGTGCGGCTCCCGGCGAGCT
GGCGCCCCCGTCTGCGTCCCGCGCGCCCGGCCCTGCTCGCGCCCGCGCATTGCGCCGCAGTCTC
GGCTGCGGCTGCGGGACGCGCGGTGTGTGGAGGGGACCTCACAAGTTCTTCCAAGTTTGCAGCA
TGATCCCATTGCTTCTGTCCCTGCTGGCAGCTCTGGTCCTGACCCAAGCCCCTGCAGCCCTCGC
TGATGACCTGAAAGAAGACAGCTCAGAGGATCGAGCCTTTCGGGTGCGCATCGGTGCCGCGCAG
CTGCGGGGTGTGCTGGGCGGTGCCCTGGCCATCCCATGCCACGTCCACCACCTGAGGCCGCCGC
CCAGCCGCCGGGCCGCGCCGGGCTTTCCCCGAGTCAAATGGACCTTCCTGTCCGGGGACCGGGA
GGTGGAGGTGCTGGTGGCGCGCGGGCTGCGCGTCAAGGTAAACGAAGCCTATCGGTTCCGCGTG
GCGCTGCCTGCCTACCCCGCATCGCTCACAGATGTGTCTTTAGTATTGAGCGAACTGCGGCCCA
ATGATTCCGGGGTCTATCGCTGCGAGGTCCAGCACGGTATCGACGACAGCAGTGATGCTGTGGA
AGTCAAGGTCAAAGGGGTCGTCTTCCTCTACCGAGAGGGCTCTGCCCGCTATGCTTTCTCCTTC
GCTGGAGCCCAGGAAGCCTGTGCTCGCATCGGAGCCCGAATTGCCACCCCTGAGCAGCTGTATG
CTGCCTACCTCGGCGGCTATGAACAGTGTGATGCTGGCTGGCTGTCCGACCAAACCGTGAGGTA
CCCCATCCAGAACCCACGAGAAGCCTGTTATGGAGACATGGATGGCTACCCTGGAGTGCGGAAT
TACGGAGTGGTGGGTCCTGATGATCTCTACGATGTCTACTGTTATGCCGAAGACCTAAATGGAG
AACTGTTCCTAGGTGCCCCTCCCGGCAAGCTGACGTGGGAGGAGGCTCGGGACTACTGTCTGGA
ACGCGGTGCTCAGATCGCTAGCACGGGCCAGCTATACGCGGCATGGAATGGCGGCTTGGACAGA
TGTAGCCCTGGCTGGCTGGCTGATGGCAGTGTGCGGTACCCCATCATCACGCCCAGCCAACGCT
GTGGGGGAGGCCTGCCAGGAGTCAAGACCCTCTTCCTCTTTCCCAACCAGACTGGCTTCCCCAG
CAAGCAGAACCGCTTCAATGTCTACTGCTTCCGAGACTCTGCCCATCCCTCTGCCTTCTCTGAG
GCCTCCAGCCCAGCCTCTGATGGACTAGAGGCCATTGTCACAGTGACAGAGAAGCTGGAGGAAC
TGCAGTTGCCTCAGGAAGCTGTGGAGAGCGAGTCTCGTGGGGCGATCTACTCCATCCCCATCAC
AGAAGATGGGGGAGGAGGAAGCTCTACCCCAGAAGACCCAGCAGAGGCCCCCAGGACTCCTCTA
GAATCAGAAACCCAATCCGTTGCACCACCTACCGGGTCCTCAGAAGAGGAAGGCGAAGCCCTGG
AGGAAGAAGAAAGATTCAAAGACACAGAGACTCCGAAGGAAGAGAAGGAGCAGGAGAACCTGTG
GGTGTGGCCCACGGAGCTCAGCAGCCCTCTCCCTACTGGCTTGGAAACAGAGCACTCACTCTCC
CAGGTGTCCCCACCAGCCCAGGCAGTTCTACAGCTGGGTGCATCACCTTCTCCCAGGCCTCCAA
GGGTCCATGGACCGCCTGCAGAGACTTTGCAACCCCCAAGGGAGGGAAGCCTCACATCTACTCC
AGATGGGGCAAGAGAAGTAGCGGGGGAAACTGGGAGCCCTGAGCTCTCTGGGGTTCCTCGAGAA
AGCGAGGAGGCAGGAAGCTCCAGCTTGGAGGATGGCCCTTCCCTCCTTCCAGCGACATGGGCCC
CTGTGGGTACCAGGGAGCTGGAGACCCCCTCAGAAGAGAAGTCTGGAAGAACTGTTCTGACAGG
CACATCAGTGCAGGCCCAGCCAGTGCTGCCCACCGACAGTGCCAGCCGAGGTGGAGTGGCTGTG
GCTCCCTCATCAGGTAATTCTGCCGAAGGCTCGATGCCCGCCTTTCTCCTTTTCCTCCTCCTCC
AGCTCTGGGCCACCTGATCACGCTGGTCGGTCGGCCTTTAATCCACCTTCTCCCCGGACCCTCT
GGGCCTTTGCCCTCATTCCCTCTCCTGTCTCTCCCTGTGGATCTTTCTTCCATTCTGTCCCTTG
CGCCCCAGTTCTCTGATCCTCTGCTCCCCGGCCCTACCGCTGACCCCCACCACTGACCCTTGGG
CCCTCTGCTGTAGCTCCCATGTCACTGGCCACACAGGATGTCCTCAAGTCTCTTCCTGGTGCCC
TCACCAGCCTTCTCGACCCTTGAAGGCAGGCCTGCCATCTGCTGTCCCCTCCCTTGTGCCTTTT
GTTCCATCCCTTTAATCACCTCCCATGGATTCCAGGGACGCCTGAGAGACCATCCCTGCCCCTC
ACCTCTGGGGACCAGAATAGTCACCCCAAAGAGCCTTAAGCCACTACTTCTGTGAAGTATTTTT
TGACTGTTTCATGGAAAACAAGCCTTGGAAATAAATCTGTATTAAACTGCTTTGTACCCAGCTG
TTGACACCCAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039101784 ⟹ XP_038957712

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,763,771 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,465,898 (-)	NCBI

RefSeq Acc Id:

XM_039101786 ⟹ XP_038957714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,763,863 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,465,898 (-)	NCBI

RefSeq Acc Id:

XM_039101787 ⟹ XP_038957715

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,760 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,467,717 (-)	NCBI

RefSeq Acc Id:

XM_039101788 ⟹ XP_038957716

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,763 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,467,717 (-)	NCBI

RefSeq Acc Id:

XM_039101789 ⟹ XP_038957717

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,763,771 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,465,813 (-)	NCBI

RefSeq Acc Id:

XM_039101790 ⟹ XP_038957718

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,763 (-)	NCBI
mRatBN7.2	2	173,454,479 - 173,466,774 (-)	NCBI

RefSeq Acc Id:

XM_063281342 ⟹ XP_063137412

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,753,090 - 175,763,772 (-)	NCBI

RefSeq Acc Id:

XM_063281343 ⟹ XP_063137413

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,764,623 (-)	NCBI

RefSeq Acc Id:

XM_063281344 ⟹ XP_063137414

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,548 (-)	NCBI

RefSeq Acc Id:

XM_063281346 ⟹ XP_063137416

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,740 (-)	NCBI

RefSeq Acc Id:

XM_063281347 ⟹ XP_063137417

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,763,773 (-)	NCBI

RefSeq Acc Id:

XM_063281348 ⟹ XP_063137418

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,752,333 - 175,765,741 (-)	NCBI

RefSeq Acc Id:

XM_063281349 ⟹ XP_063137419

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	175,753,090 - 175,765,766 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001028837	(Get FASTA)	NCBI Sequence Viewer
	NP_037048	(Get FASTA)	NCBI Sequence Viewer
	XP_038957712	(Get FASTA)	NCBI Sequence Viewer
	XP_038957714	(Get FASTA)	NCBI Sequence Viewer
	XP_038957715	(Get FASTA)	NCBI Sequence Viewer
	XP_038957716	(Get FASTA)	NCBI Sequence Viewer
	XP_038957717	(Get FASTA)	NCBI Sequence Viewer
	XP_038957718	(Get FASTA)	NCBI Sequence Viewer
	XP_063137412	(Get FASTA)	NCBI Sequence Viewer
	XP_063137413	(Get FASTA)	NCBI Sequence Viewer
	XP_063137414	(Get FASTA)	NCBI Sequence Viewer
	XP_063137416	(Get FASTA)	NCBI Sequence Viewer
	XP_063137417	(Get FASTA)	NCBI Sequence Viewer
	XP_063137418	(Get FASTA)	NCBI Sequence Viewer
	XP_063137419	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA87847	(Get FASTA)	NCBI Sequence Viewer
	CAA56255	(Get FASTA)	NCBI Sequence Viewer
	CAA60160	(Get FASTA)	NCBI Sequence Viewer
	CAA82215	(Get FASTA)	NCBI Sequence Viewer
	EDM00746	(Get FASTA)	NCBI Sequence Viewer
	EDM00747	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000025496
GenBank Protein	P55068	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001028837 ⟸ NM_001033665
- Peptide Label:	isoform 1 precursor
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot), G3V8G4 (UniProtKB/TrEMBL), A6J642 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIPLLLSLLAALVLTQAPAALADDLKEDSSEDRAFRVRIGAAQLRGVLGGALAIPCHVHHLRPP PSRRAAPGFPRVKWTFLSGDREVEVLVARGLRVKVNEAYRFRVALPAYPASLTDVSLVLSELRP NDSGVYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFAGAQEACARIGARIATPEQLY AAYLGGYEQCDAGWLSDQTVRYPIQNPREACYGDMDGYPGVRNYGVVGPDDLYDVYCYAEDLNG ELFLGAPPGKLTWEEARDYCLERGAQIASTGQLYAAWNGGLDRCSPGWLADGSVRYPIITPSQR CGGGLPGVKTLFLFPNQTGFPSKQNRFNVYCFRDSAHPSAFSEASSPASDGLEAIVTVTEKLEE LQLPQEAVESESRGAIYSIPITEDGGGGSSTPEDPAEAPRTPLESETQSVAPPTGSSEEEGEAL EEEERFKDTETPKEEKEQENLWVWPTELSSPLPTGLETEHSLSQVSPPAQAVLQLGASPSPRPP RVHGPPAETLQPPREGSLTSTPDGAREVAGETGSPELSGVPRESEEAGSSSLEDGPSLLPATWA PVGTRELETPSEEKSGRTVLTGTSVQAQPVLPTDSASRGGVAVAPSSGDCIPSPCHNGGTCLEE KEGFRCLCLPGYGGDLCDVGLHFCSPGWEAFQGACYKHFSTRRSWEEAESQCRALGAHLTSICT PEEQDFVNDRYREYQWIGLNDRTIEGDFLWSDGAPLLYENWNPGQPDSYFLSGENCVVMVWHDQ GQWSDVPCNYHLSYTCKMGLVSCGPPPQLPLAQIFGRPRLRYAVDTVLRYRCRDGLAQRNLPLI RCQENGLWEAPQISCVPRRPARALRSMTAPEGPRGQLPRQRKALLTPPSSL hide sequence

RefSeq Acc Id:	NP_037048 ⟸ NM_012916
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A6J643 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIPLLLSLLAALVLTQAPAALADDLKEDSSEDRAFRVRIGAAQLRGVLGGALAIPCHVHHLRPP PSRRAAPGFPRVKWTFLSGDREVEVLVARGLRVKVNEAYRFRVALPAYPASLTDVSLVLSELRP NDSGVYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFAGAQEACARIGARIATPEQLY AAYLGGYEQCDAGWLSDQTVRYPIQNPREACYGDMDGYPGVRNYGVVGPDDLYDVYCYAEDLNG ELFLGAPPGKLTWEEARDYCLERGAQIASTGQLYAAWNGGLDRCSPGWLADGSVRYPIITPSQR CGGGLPGVKTLFLFPNQTGFPSKQNRFNVYCFRDSAHPSAFSEASSPASDGLEAIVTVTEKLEE LQLPQEAVESESRGAIYSIPITEDGGGGSSTPEDPAEAPRTPLESETQSVAPPTGSSEEEGEAL EEEERFKDTETPKEEKEQENLWVWPTELSSPLPTGLETEHSLSQVSPPAQAVLQLGASPSPRPP RVHGPPAETLQPPREGSLTSTPDGAREVAGETGSPELSGVPRESEEAGSSSLEDGPSLLPATWA PVGTRELETPSEEKSGRTVLTGTSVQAQPVLPTDSASRGGVAVAPSSGNSAEGSMPAFLLFLLL QLWAT hide sequence

Ensembl Acc Id:

ENSRNOP00000070660 ⟸ ENSRNOT00000083116

Ensembl Acc Id:

ENSRNOP00000025496 ⟸ ENSRNOT00000025496

RefSeq Acc Id:	XP_038957715 ⟸ XM_039101787
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957716 ⟸ XM_039101788
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957718 ⟸ XM_039101790
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957714 ⟸ XM_039101786
- Peptide Label:	isoform X2
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957712 ⟸ XM_039101784
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038957717 ⟸ XM_039101789
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063137418 ⟸ XM_063281348
- Peptide Label:	isoform X4
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot), A6J642 (UniProtKB/TrEMBL), G3V8G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137416 ⟸ XM_063281346
- Peptide Label:	isoform X4
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot), A6J642 (UniProtKB/TrEMBL), G3V8G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137414 ⟸ XM_063281344
- Peptide Label:	isoform X4
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot), A6J642 (UniProtKB/TrEMBL), G3V8G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137413 ⟸ XM_063281343
- Peptide Label:	isoform X1
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063137417 ⟸ XM_063281347
- Peptide Label:	isoform X4
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot), A6J642 (UniProtKB/TrEMBL), G3V8G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137419 ⟸ XM_063281349
- Peptide Label:	isoform X3
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063137412 ⟸ XM_063281342
- Peptide Label:	isoform X3
- UniProtKB:	Q63513 (UniProtKB/Swiss-Prot), Q63040 (UniProtKB/Swiss-Prot), Q62860 (UniProtKB/Swiss-Prot), P55068 (UniProtKB/Swiss-Prot)

Protein Domains

C-type lectin EGF-like Ig-like Ig-like V-type Link Sushi

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P55068-F1-model_v2	AlphaFold	P55068	1-883	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2194	AgrOrtholog
BioCyc Gene	G2FUF-52523	BioCyc
Ensembl Genes	ENSRNOG00000018798	Ensembl, ENTREZGENE
	ENSRNOG00000058727	Ensembl
Ensembl Transcript	ENSRNOT00000025496	ENTREZGENE
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
	3.10.100.10	UniProtKB/Swiss-Prot
	Complement Module, domain 1	UniProtKB/Swiss-Prot
	Laminin	UniProtKB/Swiss-Prot
InterPro	C-type_lectin-like	UniProtKB/Swiss-Prot
	C-type_lectin-like/link_sf	UniProtKB/Swiss-Prot
	C-type_lectin_CS	UniProtKB/Swiss-Prot
	CTDL_fold	UniProtKB/Swiss-Prot
	EGF-like_dom	UniProtKB/Swiss-Prot
	Hyaluronan_bind_Proteoglycan	UniProtKB/Swiss-Prot
	Ig-like_dom	UniProtKB/Swiss-Prot
	Ig-like_dom_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	Ig/MHC_CS	UniProtKB/Swiss-Prot
	Ig_sub	UniProtKB/Swiss-Prot
	Ig_V-set	UniProtKB/Swiss-Prot
	Link_dom	UniProtKB/Swiss-Prot
	Sushi/SCR/CCP_sf	UniProtKB/Swiss-Prot
	Sushi_SCR_CCP_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:25393	UniProtKB/Swiss-Prot
NCBI Gene	25393	ENTREZGENE
PANTHER	AGGRECAN/VERSICAN PROTEOGLYCAN	UniProtKB/Swiss-Prot
	BREVICAN CORE PROTEIN	UniProtKB/Swiss-Prot
Pfam	EGF	UniProtKB/Swiss-Prot
	Lectin_C	UniProtKB/Swiss-Prot
	Sushi	UniProtKB/Swiss-Prot
	V-set	UniProtKB/Swiss-Prot
	Xlink	UniProtKB/Swiss-Prot
PhenoGen	Bcan	PhenoGen
PRINTS	LINKMODULE	UniProtKB/Swiss-Prot
PROSITE	C_TYPE_LECTIN_1	UniProtKB/Swiss-Prot
	C_TYPE_LECTIN_2	UniProtKB/Swiss-Prot
	EGF_1	UniProtKB/Swiss-Prot
	EGF_2	UniProtKB/Swiss-Prot
	EGF_3	UniProtKB/Swiss-Prot
	IG_LIKE	UniProtKB/Swiss-Prot
	IG_MHC	UniProtKB/Swiss-Prot
	LINK_1	UniProtKB/Swiss-Prot
	LINK_2	UniProtKB/Swiss-Prot
	SUSHI	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000018798	RatGTEx
	ENSRNOG00000058727	RatGTEx
SMART	CCP	UniProtKB/Swiss-Prot
	CLECT	UniProtKB/Swiss-Prot
	EGF	UniProtKB/Swiss-Prot
	IGv	UniProtKB/Swiss-Prot
	LINK	UniProtKB/Swiss-Prot
	SM00409	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot
	SSF56436	UniProtKB/Swiss-Prot
	SSF57535	UniProtKB/Swiss-Prot
TIGR	TC218890
UniProt	A6J642	ENTREZGENE, UniProtKB/TrEMBL
	A6J643	ENTREZGENE, UniProtKB/TrEMBL
	G3V8G4	ENTREZGENE, UniProtKB/TrEMBL
	P55068	ENTREZGENE, UniProtKB/Swiss-Prot
	Q62860	ENTREZGENE
	Q63040	ENTREZGENE
	Q63513	ENTREZGENE
UniProt Secondary	Q62860	UniProtKB/Swiss-Prot
	Q63040	UniProtKB/Swiss-Prot
	Q63513	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Bcan	brevican	LOC100910284	brevican core protein-like	Data merged from RGD:6499197	737654	PROVISIONAL
2012-07-05	LOC100910284	brevican core protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2002-06-10	Bcan	Brevican			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIA