Arl4a (ARF like GTPase 4A) - Rat Genome Database

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Gene: Arl4a (ARF like GTPase 4A) Rattus norvegicus
Analyze
Symbol: Arl4a
Name: ARF like GTPase 4A (Ensembl:ADP-ribosylation factor like GTPase 4A)
RGD ID: 2152
Description: Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to act upstream of or within brown fat cell differentiation. Predicted to be located in nucleolus. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human ARL4A (ARF like GTPase 4A); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosylation factor like GTPase 4A; ADP-ribosylation factor-like 4; ADP-ribosylation factor-like 4A; ADP-ribosylation factor-like protein 4A; ADP-ribosylation-like 4; Arl4; MGC108709
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8662,809,287 - 62,811,297 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl662,804,548 - 62,820,760 (-)EnsemblGRCr8
mRatBN7.2657,079,496 - 57,084,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl657,078,812 - 57,085,066 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx657,345,445 - 57,347,455 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0657,660,381 - 57,662,391 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0657,151,623 - 57,153,633 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0659,945,926 - 59,950,586 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl659,948,577 - 59,950,586 (-)Ensemblrn6Rnor6.0
Rnor_5.0669,534,037 - 69,538,697 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4659,212,599 - 59,214,609 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera656,132,664 - 56,134,674 (-)NCBICelera
RGSC_v3.1659,215,725 - 59,217,735 (-)NCBI
Cytogenetic Map6q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
choline  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
dibenz[a,h]anthracene  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydrogen cyanide  (ISO)
indole-3-methanol  (EXP)
inulin  (ISO)
isobutanol  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
levofloxacin  (EXP)
lipopolysaccharide  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
N-methylformamide  (ISO)
naled  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phorone  (EXP)
pirinixic acid  (ISO)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
toxaphene  (EXP)
trichloroethene  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (ISO)
nucleolus  (IEA,ISO,ISS)
nucleus  (IEA,ISO,ISS)
plasma membrane  (IBA,IEA,ISO,ISS)

Molecular Function
GTP binding  (IBA,IEA,ISO,ISS)
GTPase activity  (IEA)
nucleotide binding  (IEA)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells. Schurmann A, etal., J Biol Chem 1994 Jun 3;269(22):15683-8.
7. Reduced sperm count and normal fertility in male mice with targeted disruption of the ADP-ribosylation factor-like 4 (Arl4) gene. Schurmann A, etal., Mol Cell Biol 2002 Apr;22(8):2761-8.
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10980193   PMID:12477932   PMID:15489334   PMID:17398095   PMID:18492766  


Genomics

Comparative Map Data
Arl4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8662,809,287 - 62,811,297 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl662,804,548 - 62,820,760 (-)EnsemblGRCr8
mRatBN7.2657,079,496 - 57,084,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl657,078,812 - 57,085,066 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx657,345,445 - 57,347,455 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0657,660,381 - 57,662,391 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0657,151,623 - 57,153,633 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0659,945,926 - 59,950,586 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl659,948,577 - 59,950,586 (-)Ensemblrn6Rnor6.0
Rnor_5.0669,534,037 - 69,538,697 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4659,212,599 - 59,214,609 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera656,132,664 - 56,134,674 (-)NCBICelera
RGSC_v3.1659,215,725 - 59,217,735 (-)NCBI
Cytogenetic Map6q21NCBI
ARL4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38712,686,903 - 12,690,958 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl712,686,602 - 12,690,958 (+)Ensemblhg38GRCh38
GRCh37712,726,528 - 12,730,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36712,693,006 - 12,697,084 (+)NCBIBuild 36Build 36hg18NCBI36
Celera712,704,156 - 12,708,234 (+)NCBICelera
Cytogenetic Map7p21.3NCBI
HuRef712,607,443 - 12,611,550 (+)NCBIHuRef
CHM1_1712,726,522 - 12,730,629 (+)NCBICHM1_1
T2T-CHM13v2.0712,817,976 - 12,822,031 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2712,777,588 - 12,781,695 (+)NCBI
Arl4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391240,083,290 - 40,087,986 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1240,055,446 - 40,088,024 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381240,033,291 - 40,037,987 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1240,005,447 - 40,038,025 (-)Ensemblmm10GRCm38
MGSCv371240,759,878 - 40,764,574 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361240,543,714 - 40,548,410 (-)NCBIMGSCv36mm8
Celera1241,461,600 - 41,466,296 (-)NCBICelera
Cytogenetic Map12B1NCBI
cM Map1218.06NCBI
Arl4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541016,400,342 - 16,403,200 (+)Ensembl
ChiLan1.0NW_00495541016,400,342 - 16,403,200 (+)NCBIChiLan1.0ChiLan1.0
LOC100986273
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2617,553,211 - 17,558,311 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1765,877,927 - 65,881,296 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0713,379,627 - 13,383,603 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1712,723,991 - 12,727,761 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl712,725,299 - 12,725,901 (+)EnsemblpanPan2panpan1.1
ARL4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11427,522,766 - 27,526,404 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1427,034,654 - 27,036,978 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01427,349,211 - 27,351,535 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1427,349,181 - 27,351,535 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11427,519,115 - 27,521,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01427,249,798 - 27,252,122 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01427,566,321 - 27,568,645 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arl4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511872,030,368 - 72,032,687 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936795355,256 - 357,515 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936795355,256 - 357,560 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl982,225,272 - 82,231,900 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1982,224,985 - 82,228,951 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2990,366,105 - 90,368,735 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARL4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12145,407,194 - 45,409,476 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604259,064,746 - 59,068,941 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473917,254,603 - 17,256,200 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473917,254,603 - 17,256,833 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Arl4a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1753,269,482 - 53,274,172 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Arl4a
14 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:31
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000005800
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63902865963457441Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat

Markers in Region
Y12577  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2657,082,253 - 57,082,377 (+)MAPPERmRatBN7.2
Rnor_6.0659,948,684 - 59,948,807NCBIRnor6.0
Rnor_5.0669,536,795 - 69,536,918UniSTSRnor5.0
RGSC_v3.4659,212,707 - 59,212,830UniSTSRGSC3.4
Celera656,132,772 - 56,132,895UniSTS
Cytogenetic Map6q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005800   ⟹   ENSRNOP00000005800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl659,948,577 - 59,950,586 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108440   ⟹   ENSRNOP00000084810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl662,804,548 - 62,820,760 (-)Ensembl
mRatBN7.2 Ensembl657,078,812 - 57,085,066 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118685   ⟹   ENSRNOP00000089325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl662,804,548 - 62,820,760 (-)Ensembl
mRatBN7.2 Ensembl657,078,812 - 57,083,785 (-)Ensembl
RefSeq Acc Id: NM_019186   ⟹   NP_062059
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8662,809,287 - 62,811,297 (-)NCBI
mRatBN7.2657,082,146 - 57,084,156 (-)NCBI
Rnor_6.0659,948,576 - 59,950,586 (-)NCBI
Rnor_5.0669,534,037 - 69,538,697 (-)NCBI
RGSC_v3.4659,212,599 - 59,214,609 (-)RGD
Celera656,132,664 - 56,134,674 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240051   ⟹   XP_006240113
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8662,809,287 - 62,811,272 (-)NCBI
mRatBN7.2657,079,496 - 57,083,748 (-)NCBI
Rnor_6.0659,945,926 - 59,950,126 (-)NCBI
Rnor_5.0669,534,037 - 69,538,697 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240052   ⟹   XP_006240114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8662,809,287 - 62,811,272 (-)NCBI
mRatBN7.2657,079,496 - 57,083,696 (-)NCBI
Rnor_6.0659,945,926 - 59,950,122 (-)NCBI
Rnor_5.0669,534,037 - 69,538,697 (-)NCBI
Sequence:
RefSeq Acc Id: NP_062059   ⟸   NM_019186
- UniProtKB: P61214 (UniProtKB/Swiss-Prot),   A6HBC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240113   ⟸   XM_006240051
- Peptide Label: isoform X1
- UniProtKB: P61214 (UniProtKB/Swiss-Prot),   A6HBC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240114   ⟸   XM_006240052
- Peptide Label: isoform X1
- UniProtKB: P61214 (UniProtKB/Swiss-Prot),   A6HBC6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005800   ⟸   ENSRNOT00000005800
Ensembl Acc Id: ENSRNOP00000089325   ⟸   ENSRNOT00000118685
Ensembl Acc Id: ENSRNOP00000084810   ⟸   ENSRNOT00000108440

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61214-F1-model_v2 AlphaFold P61214 1-200 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694569
Promoter ID:EPDNEW_R5094
Type:initiation region
Name:Arl4a_1
Description:ADP-ribosylation factor like GTPase 4A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0659,950,683 - 59,950,743EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2152 AgrOrtholog
BioCyc Gene G2FUF-37749 BioCyc
Ensembl Genes ENSRNOG00000004282 Ensembl
  ENSRNOG00000069300 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000108440 ENTREZGENE
  ENSRNOT00000108440.1 UniProtKB/Swiss-Prot
  ENSRNOT00000118685 ENTREZGENE
  ENSRNOT00000118685.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7373646 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase_ARF UniProtKB/Swiss-Prot
  Small_GTPase_ARF/SAR UniProtKB/Swiss-Prot
KEGG Report rno:29308 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108709 IMAGE-MGC_LOAD
NCBI Gene 29308 ENTREZGENE
PANTHER PTHR11711 UniProtKB/Swiss-Prot
Pfam Arf UniProtKB/Swiss-Prot
PhenoGen Arl4a PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot
PROSITE ARF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004282 RatGTEx
  ENSRNOG00000069300 RatGTEx
SMART ARF UniProtKB/Swiss-Prot
  RAB UniProtKB/Swiss-Prot
  RAS UniProtKB/Swiss-Prot
  SAR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
TIGR TC230665
UniProt A6HBC5_RAT UniProtKB/TrEMBL
  A6HBC6 ENTREZGENE, UniProtKB/TrEMBL
  ARL4A_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P41275 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-11-07 Arl4a  ARF like GTPase 4A  Arl4a  ADP-ribosylation factor like GTPase 4A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-19 Arl4a  ADP-ribosylation factor like GTPase 4A  Arl4a  ADP-ribosylation factor-like 4A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Arl4a  ADP-ribosylation factor-like 4A  Arl4  ADP-ribosylation factor-like 4  Symbol and Name updated 1299863 APPROVED
2005-09-30 Arl4        Symbol and Name status set to provisional 70820 PROVISIONAL
2005-02-25   ADP-ribosylation factor-like 4  Arl4  ADP-ribosylation-like 4   Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2002-06-10 Arl4  ADP-ribosylation-like 4       Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in adipocytes 69758
gene_function may bind GTP 69758
gene_process may play a role in GTP binding and hydrolysis 69758