Arl4a (ARF like GTPase 4A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Arl4a (ARF like GTPase 4A) Rattus norvegicus
Analyze
Symbol: Arl4a
Name: ARF like GTPase 4A (Ensembl:ADP-ribosylation factor like GTPase 4A)
RGD ID: 2152
Description: Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to act upstream of or within brown fat cell differentiation. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human ARL4A (ARF like GTPase 4A); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosylation factor like GTPase 4A; ADP-ribosylation factor-like 4; ADP-ribosylation factor-like 4A; ADP-ribosylation factor-like protein 4A; ADP-ribosylation-like 4; Arl4; MGC108709
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8662,809,287 - 62,811,297 (-)NCBIGRCr8
mRatBN7.2657,079,496 - 57,084,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl657,078,812 - 57,085,066 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx657,345,445 - 57,347,455 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0657,660,381 - 57,662,391 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0657,151,623 - 57,153,633 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0659,945,926 - 59,950,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl659,948,577 - 59,950,586 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0669,534,037 - 69,538,697 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4659,212,599 - 59,214,609 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1659,215,725 - 59,217,735 (-)NCBI
Celera656,132,664 - 56,134,674 (-)NCBICelera
Cytogenetic Map6q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
choline  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
dibenz[a,h]anthracene  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydrogen cyanide  (ISO)
indole-3-methanol  (EXP)
inulin  (ISO)
isobutanol  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
levofloxacin  (EXP)
lipopolysaccharide  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
N-methylformamide  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phorone  (EXP)
pirinixic acid  (ISO)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
toxaphene  (EXP)
trichloroethene  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
cytosol  (IEA,ISO)
nucleolus  (ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (ISO,ISS)
plasma membrane  (IBA,ISO,ISS)

Molecular Function
GTP binding  (IBA,ISO,ISS)
GTPase activity  (IEA)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells. Schurmann A, etal., J Biol Chem 1994 Jun 3;269(22):15683-8.
7. Reduced sperm count and normal fertility in male mice with targeted disruption of the ADP-ribosylation factor-like 4 (Arl4) gene. Schurmann A, etal., Mol Cell Biol 2002 Apr;22(8):2761-8.
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10980193   PMID:12477932   PMID:15489334   PMID:17398095   PMID:18492766  


Genomics

Comparative Map Data
Arl4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8662,809,287 - 62,811,297 (-)NCBIGRCr8
mRatBN7.2657,079,496 - 57,084,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl657,078,812 - 57,085,066 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx657,345,445 - 57,347,455 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0657,660,381 - 57,662,391 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0657,151,623 - 57,153,633 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0659,945,926 - 59,950,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl659,948,577 - 59,950,586 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0669,534,037 - 69,538,697 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4659,212,599 - 59,214,609 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1659,215,725 - 59,217,735 (-)NCBI
Celera656,132,664 - 56,134,674 (-)NCBICelera
Cytogenetic Map6q21NCBI
ARL4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38712,686,903 - 12,690,958 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl712,686,856 - 12,690,958 (+)EnsemblGRCh38hg38GRCh38
GRCh37712,726,528 - 12,730,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36712,693,006 - 12,697,084 (+)NCBINCBI36Build 36hg18NCBI36
Celera712,704,156 - 12,708,234 (+)NCBICelera
Cytogenetic Map7p21.3NCBI
HuRef712,607,443 - 12,611,550 (+)NCBIHuRef
CHM1_1712,726,522 - 12,730,629 (+)NCBICHM1_1
T2T-CHM13v2.0712,817,976 - 12,822,031 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2712,777,588 - 12,781,695 (+)NCBI
Arl4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391240,083,290 - 40,087,986 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1240,055,446 - 40,088,024 (-)EnsemblGRCm39 Ensembl
GRCm381240,033,291 - 40,037,987 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1240,005,447 - 40,038,025 (-)EnsemblGRCm38mm10GRCm38
MGSCv371240,759,878 - 40,764,574 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361240,543,714 - 40,548,410 (-)NCBIMGSCv36mm8
Celera1241,461,600 - 41,466,296 (-)NCBICelera
Cytogenetic Map12B1NCBI
cM Map1218.06NCBI
Arl4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541016,400,342 - 16,403,200 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541016,400,342 - 16,403,200 (+)NCBIChiLan1.0ChiLan1.0
LOC100986273
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2617,553,211 - 17,558,311 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1765,877,927 - 65,881,296 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0713,379,627 - 13,383,603 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1712,723,991 - 12,727,761 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl712,725,299 - 12,725,901 (+)Ensemblpanpan1.1panPan2
ARL4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11427,522,766 - 27,526,404 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1427,034,654 - 27,036,978 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01427,349,211 - 27,351,535 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1427,349,181 - 27,351,535 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11427,519,115 - 27,521,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01427,249,798 - 27,252,122 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01427,566,321 - 27,568,645 (+)NCBIUU_Cfam_GSD_1.0
Arl4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511872,030,368 - 72,032,687 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936795355,256 - 357,515 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936795355,256 - 357,560 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl982,225,272 - 82,231,900 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1982,224,985 - 82,228,951 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2990,366,105 - 90,368,735 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARL4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12145,407,194 - 45,409,476 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604259,064,746 - 59,068,941 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473917,254,603 - 17,256,200 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473917,254,603 - 17,256,833 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arl4a
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:31
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000005800
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat

Markers in Region
Y12577  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2657,082,253 - 57,082,377 (+)MAPPERmRatBN7.2
Rnor_6.0659,948,684 - 59,948,807NCBIRnor6.0
Rnor_5.0669,536,795 - 69,536,918UniSTSRnor5.0
RGSC_v3.4659,212,707 - 59,212,830UniSTSRGSC3.4
Celera656,132,772 - 56,132,895UniSTS
Cytogenetic Map6q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000005800   ⟹   ENSRNOP00000005800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl659,948,577 - 59,950,586 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108440   ⟹   ENSRNOP00000084810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl657,078,812 - 57,085,066 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118685   ⟹   ENSRNOP00000089325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl657,078,812 - 57,083,785 (-)Ensembl
RefSeq Acc Id: NM_019186   ⟹   NP_062059
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8662,809,287 - 62,811,297 (-)NCBI
mRatBN7.2657,082,146 - 57,084,156 (-)NCBI
Rnor_6.0659,948,576 - 59,950,586 (-)NCBI
Rnor_5.0669,534,037 - 69,538,697 (-)NCBI
RGSC_v3.4659,212,599 - 59,214,609 (-)RGD
Celera656,132,664 - 56,134,674 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240051   ⟹   XP_006240113
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8662,809,287 - 62,811,272 (-)NCBI
mRatBN7.2657,079,496 - 57,083,748 (-)NCBI
Rnor_6.0659,945,926 - 59,950,126 (-)NCBI
Rnor_5.0669,534,037 - 69,538,697 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240052   ⟹   XP_006240114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8662,809,287 - 62,811,272 (-)NCBI
mRatBN7.2657,079,496 - 57,083,696 (-)NCBI
Rnor_6.0659,945,926 - 59,950,122 (-)NCBI
Rnor_5.0669,534,037 - 69,538,697 (-)NCBI
Sequence:
RefSeq Acc Id: NP_062059   ⟸   NM_019186
- UniProtKB: P61214 (UniProtKB/Swiss-Prot),   A6HBC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240113   ⟸   XM_006240051
- Peptide Label: isoform X1
- UniProtKB: P61214 (UniProtKB/Swiss-Prot),   A6HBC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240114   ⟸   XM_006240052
- Peptide Label: isoform X1
- UniProtKB: P61214 (UniProtKB/Swiss-Prot),   A6HBC6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005800   ⟸   ENSRNOT00000005800
Ensembl Acc Id: ENSRNOP00000089325   ⟸   ENSRNOT00000118685
Ensembl Acc Id: ENSRNOP00000084810   ⟸   ENSRNOT00000108440

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61214-F1-model_v2 AlphaFold P61214 1-200 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694569
Promoter ID:EPDNEW_R5094
Type:initiation region
Name:Arl4a_1
Description:ADP-ribosylation factor like GTPase 4A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0659,950,683 - 59,950,743EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2152 AgrOrtholog
BioCyc Gene G2FUF-37749 BioCyc
Ensembl Genes ENSRNOG00000004282 Ensembl
  ENSRNOG00000069300 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055001346 UniProtKB/Swiss-Prot
  ENSRNOG00055019623 UniProtKB/Swiss-Prot
  ENSRNOG00060005750 UniProtKB/Swiss-Prot
  ENSRNOG00065009652 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000108440.1 UniProtKB/Swiss-Prot
  ENSRNOT00000118685.1 UniProtKB/Swiss-Prot
  ENSRNOT00055002208 UniProtKB/Swiss-Prot
  ENSRNOT00055033488 UniProtKB/Swiss-Prot
  ENSRNOT00055033492 UniProtKB/Swiss-Prot
  ENSRNOT00060009532 UniProtKB/Swiss-Prot
  ENSRNOT00060009540 UniProtKB/Swiss-Prot
  ENSRNOT00065015479 UniProtKB/Swiss-Prot
  ENSRNOT00065015481 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7373646 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_ARF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_ARF/SAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29308 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:108709 IMAGE-MGC_LOAD
NCBI Gene 29308 ENTREZGENE
PANTHER ADP RIBOSYLATION FACTOR-RELATED UniProtKB/TrEMBL
  ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11711 UniProtKB/Swiss-Prot
Pfam Arf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arl4a PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004282 RatGTEx
  ENSRNOG00000069300 RatGTEx
  ENSRNOG00055001346 RatGTEx
  ENSRNOG00055019623 RatGTEx
  ENSRNOG00060005750 RatGTEx
  ENSRNOG00065009652 RatGTEx
SMART ARF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
TIGR TC230665
UniProt A6HBC5_RAT UniProtKB/TrEMBL
  A6HBC6 ENTREZGENE, UniProtKB/TrEMBL
  ARL4A_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P41275 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-11-07 Arl4a  ARF like GTPase 4A  Arl4a  ADP-ribosylation factor like GTPase 4A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-19 Arl4a  ADP-ribosylation factor like GTPase 4A  Arl4a  ADP-ribosylation factor-like 4A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Arl4a  ADP-ribosylation factor-like 4A  Arl4  ADP-ribosylation factor-like 4  Symbol and Name updated 1299863 APPROVED
2005-09-30 Arl4        Symbol and Name status set to provisional 70820 PROVISIONAL
2005-02-25   ADP-ribosylation factor-like 4  Arl4  ADP-ribosylation-like 4   Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2002-06-10 Arl4  ADP-ribosylation-like 4       Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in adipocytes 69758
gene_function may bind GTP 69758
gene_process may play a role in GTP binding and hydrolysis 69758