Itpk1 (inositol-tetrakisphosphate 1-kinase) - Rat Genome Database

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Gene: Itpk1 (inositol-tetrakisphosphate 1-kinase) Rattus norvegicus
Analyze
Symbol: Itpk1
Name: inositol-tetrakisphosphate 1-kinase
RGD ID: 1595691
Description: Predicted to enable inositol phosphate kinase activity. Predicted to be involved in necroptotic process. Predicted to act upstream of or within neural tube development. Predicted to be located in apical plasma membrane. Orthologous to human ITPK1 (inositol-tetrakisphosphate 1-kinase); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: inositol 1,3,4-triphosphate 5/6 kinase; LOC500709; similar to inositol 1,3,4-triphosphate 5/6 kinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86127,475,589 - 127,609,320 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6127,476,808 - 127,609,062 (-)EnsemblGRCr8
mRatBN7.26121,710,750 - 121,844,501 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,710,755 - 121,844,107 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6121,850,453 - 121,982,457 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,145,701 - 122,277,708 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06121,482,099 - 121,614,034 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06126,448,920 - 126,582,188 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6126,450,139 - 126,582,134 (-)Ensemblrn6Rnor6.0
Rnor_5.06135,660,943 - 135,790,645 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46126,837,135 - 126,969,350 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6119,200,722 - 119,330,748 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrobenzenesulfonic acid  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glyphosate  (ISO)
indometacin  (ISO)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
p-toluidine  (EXP)
paracetamol  (EXP)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
pinostrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8662638   PMID:11042108   PMID:16537650   PMID:19482943   PMID:29883610  


Genomics

Comparative Map Data
Itpk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86127,475,589 - 127,609,320 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6127,476,808 - 127,609,062 (-)EnsemblGRCr8
mRatBN7.26121,710,750 - 121,844,501 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,710,755 - 121,844,107 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6121,850,453 - 121,982,457 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,145,701 - 122,277,708 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06121,482,099 - 121,614,034 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06126,448,920 - 126,582,188 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6126,450,139 - 126,582,134 (-)Ensemblrn6Rnor6.0
Rnor_5.06135,660,943 - 135,790,645 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46126,837,135 - 126,969,350 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6119,200,722 - 119,330,748 (-)NCBICelera
Cytogenetic Map6q32NCBI
ITPK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381492,936,914 - 93,115,925 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1492,936,914 - 93,116,458 (-)Ensemblhg38GRCh38
GRCh371493,403,259 - 93,582,270 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361492,475,960 - 92,651,980 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341492,475,959 - 92,651,980NCBI
Celera1473,457,398 - 73,636,400 (-)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1473,584,961 - 73,762,800 (-)NCBIHuRef
CHM1_11493,341,508 - 93,520,507 (-)NCBICHM1_1
T2T-CHM13v2.01487,168,906 - 87,347,917 (-)NCBIT2T-CHM13v2.0
Itpk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912102,534,842 - 102,671,128 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12102,534,841 - 102,671,189 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3812102,568,583 - 102,704,869 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12102,568,582 - 102,704,930 (-)Ensemblmm10GRCm38
MGSCv3712103,806,793 - 103,943,079 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612102,969,633 - 103,105,919 (-)NCBIMGSCv36mm8
Celera12103,782,829 - 103,919,411 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.69NCBI
Itpk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543815,107,891 - 15,257,740 (-)Ensembl
ChiLan1.0NW_00495543815,107,992 - 15,257,730 (-)NCBIChiLan1.0ChiLan1.0
ITPK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21594,098,055 - 94,275,927 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11493,314,561 - 93,491,649 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01473,573,020 - 73,750,109 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11492,909,785 - 93,087,773 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1492,909,785 - 93,087,773 (-)EnsemblpanPan2panpan1.1
ITPK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,976,089 - 2,136,228 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl81,977,740 - 2,136,339 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha81,979,707 - 2,159,693 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.082,012,020 - 2,191,809 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl82,031,969 - 2,192,301 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.181,947,975 - 2,127,830 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.081,898,042 - 2,078,021 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.082,025,376 - 2,205,114 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Itpk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864012,402,818 - 12,536,055 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936733930,972 - 1,064,229 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936733930,986 - 1,064,223 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7114,361,968 - 114,520,793 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17114,361,976 - 114,520,805 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27120,970,535 - 121,053,191 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITPK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12470,680,791 - 70,860,132 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2470,679,303 - 70,859,587 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605357,929,735 - 58,110,383 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itpk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247349,417,939 - 9,568,702 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247349,420,232 - 9,568,655 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Itpk1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17113,843,933 - 113,976,294 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Itpk1
404 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:46
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000010656
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat

Markers in Region
D6Hmgc8  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr86127,573,671 - 127,573,897 (+)Marker Load Pipeline
mRatBN7.26121,808,842 - 121,809,068 (+)MAPPERmRatBN7.2
Rnor_6.06126,546,844 - 126,547,069NCBIRnor6.0
Rnor_5.06135,755,246 - 135,755,471UniSTSRnor5.0
Celera6119,295,584 - 119,295,809UniSTS
Cytogenetic Map6q32UniSTS
D6Hmgc9  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr86127,589,370 - 127,589,573 (+)Marker Load Pipeline
mRatBN7.26121,824,541 - 121,824,744 (+)MAPPERmRatBN7.2
Rnor_6.06126,562,543 - 126,562,745NCBIRnor6.0
Rnor_5.06135,770,945 - 135,771,147UniSTSRnor5.0
Celera6119,311,283 - 119,311,485UniSTS
Cytogenetic Map6q32UniSTS
AU048745  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q32UniSTS
Cytogenetic Map13q24UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map13q26UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map5q21UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map2q11UniSTS
Cytogenetic Map1q54UniSTS
Cytogenetic Map1q36UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map13q13UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map8q31UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map13p13UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map10q31UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map3q24UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map3p13UniSTS
AU046664  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26121,808,931 - 121,809,173 (+)MAPPERmRatBN7.2
Rnor_6.06126,546,933 - 126,547,174NCBIRnor6.0
Rnor_5.06135,755,335 - 135,755,576UniSTSRnor5.0
RGSC_v3.46126,934,249 - 126,934,490UniSTSRGSC3.4
Celera6119,295,673 - 119,295,914UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010656   ⟹   ENSRNOP00000010656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6127,476,808 - 127,609,062 (-)Ensembl
mRatBN7.2 Ensembl6121,710,755 - 121,844,107 (-)Ensembl
Rnor_6.0 Ensembl6126,450,139 - 126,582,034 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080829   ⟹   ENSRNOP00000074255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6127,476,808 - 127,609,039 (-)Ensembl
mRatBN7.2 Ensembl6121,710,755 - 121,844,107 (-)Ensembl
Rnor_6.0 Ensembl6126,450,311 - 126,582,134 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095173   ⟹   ENSRNOP00000097242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6127,476,808 - 127,550,218 (-)Ensembl
mRatBN7.2 Ensembl6121,710,755 - 121,785,253 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095210   ⟹   ENSRNOP00000097430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6127,476,808 - 127,609,062 (-)Ensembl
mRatBN7.2 Ensembl6121,710,755 - 121,844,107 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119725   ⟹   ENSRNOP00000091296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6127,476,808 - 127,608,698 (-)Ensembl
mRatBN7.2 Ensembl6121,710,755 - 121,844,107 (-)Ensembl
RefSeq Acc Id: NM_001191985   ⟹   NP_001178914
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86127,476,808 - 127,608,863 (-)NCBI
mRatBN7.26121,711,969 - 121,844,038 (-)NCBI
Rnor_6.06126,450,139 - 126,582,034 (-)NCBI
Rnor_5.06135,660,943 - 135,790,645 (-)NCBI
Celera6119,200,722 - 119,330,748 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764842   ⟹   XP_008763064
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86127,475,589 - 127,550,300 (-)NCBI
mRatBN7.26121,710,750 - 121,785,479 (-)NCBI
Rnor_6.06126,448,920 - 126,524,634 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594304   ⟹   XP_017449793
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86127,475,589 - 127,609,315 (-)NCBI
mRatBN7.26121,710,750 - 121,844,497 (-)NCBI
Rnor_6.06126,448,920 - 126,582,188 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112755   ⟹   XP_038968683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86127,475,589 - 127,609,320 (-)NCBI
mRatBN7.26121,710,750 - 121,844,501 (-)NCBI
RefSeq Acc Id: XM_063262333   ⟹   XP_063118403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86127,475,589 - 127,550,274 (-)NCBI
RefSeq Acc Id: XM_063262334   ⟹   XP_063118404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86127,475,589 - 127,574,734 (-)NCBI
RefSeq Acc Id: NP_001178914   ⟸   NM_001191985
- UniProtKB: D3ZQM7 (UniProtKB/TrEMBL),   A0A8I6AUY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763064   ⟸   XM_008764842
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AUY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449793   ⟸   XM_017594304
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K7L4 (UniProtKB/TrEMBL),   A0A8I6AUY6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074255   ⟸   ENSRNOT00000080829
Ensembl Acc Id: ENSRNOP00000010656   ⟸   ENSRNOT00000010656
RefSeq Acc Id: XP_038968683   ⟸   XM_039112755
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000097242   ⟸   ENSRNOT00000095173
Ensembl Acc Id: ENSRNOP00000091296   ⟸   ENSRNOT00000119725
Ensembl Acc Id: ENSRNOP00000097430   ⟸   ENSRNOT00000095210
RefSeq Acc Id: XP_063118404   ⟸   XM_063262334
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118403   ⟸   XM_063262333
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AUQ3 (UniProtKB/TrEMBL),   A0A8I6AUY6 (UniProtKB/TrEMBL)
Protein Domains
ATP-grasp   Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp   Inositol-tetrakisphosphate 1-kinase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7L4-F1-model_v2 AlphaFold A0A0G2K7L4 1-463 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694785
Promoter ID:EPDNEW_R5309
Type:initiation region
Name:Itpk1_1
Description:inositol-tetrakisphosphate 1-kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06126,582,131 - 126,582,191EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595691 AgrOrtholog
BioCyc Gene G2FUF-36445 BioCyc
Ensembl Genes ENSRNOG00000008051 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010656 ENTREZGENE
  ENSRNOT00000010656.9 UniProtKB/TrEMBL
  ENSRNOT00000080829 ENTREZGENE
  ENSRNOT00000080829.3 UniProtKB/TrEMBL
  ENSRNOT00000095173 ENTREZGENE
  ENSRNOT00000095173.2 UniProtKB/TrEMBL
  ENSRNOT00000095210.2 UniProtKB/TrEMBL
  ENSRNOT00000119725.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1490.220 UniProtKB/TrEMBL
  3.40.50.11370 UniProtKB/TrEMBL
  ATP-grasp fold, B domain UniProtKB/TrEMBL
InterPro ATP-grasp UniProtKB/TrEMBL
  Ins134_P3_kin UniProtKB/TrEMBL
  InsP(3)kin_ATP-grasp UniProtKB/TrEMBL
  ITPK1_N UniProtKB/TrEMBL
KEGG Report rno:500709 UniProtKB/TrEMBL
NCBI Gene 500709 ENTREZGENE
PANTHER INOSITOL-TETRAKISPHOSPHATE 1-KINASE UniProtKB/TrEMBL
  PTHR14217 UniProtKB/TrEMBL
Pfam Ins134_P3_kin UniProtKB/TrEMBL
  Ins134_P3_kin_N UniProtKB/TrEMBL
PhenoGen Itpk1 PhenoGen
PROSITE ATP_GRASP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008051 RatGTEx
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
UniProt A0A0G2K7L4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFB6_RAT UniProtKB/TrEMBL
  A0A8I6AUQ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AUY6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQM7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Itpk1  inositol-tetrakisphosphate 1-kinase  LOC683482  similar to inositol 1,3,4-triphosphate 5/6 kinase  Data merged from RGD:1586809 1643240 APPROVED
2011-08-02 Itpk1  inositol-tetrakisphosphate 1-kinase  Itpk1  inositol 1,3,4-triphosphate 5/6 kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Itpk1  inositol 1,3,4-triphosphate 5/6 kinase  LOC500709  similar to inositol 1,3,4-triphosphate 5/6 kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC500709  similar to inositol 1,3,4-triphosphate 5/6 kinase      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683482  similar to inositol 1,3,4-triphosphate 5/6 kinase      Symbol and Name status set to provisional 70820 PROVISIONAL