Itpk1 (inositol-tetrakisphosphate 1-kinase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Itpk1 (inositol-tetrakisphosphate 1-kinase) Chinchilla lanigera
Analyze
Symbol: Itpk1
Name: inositol-tetrakisphosphate 1-kinase
RGD ID: 8778942
Description: ENCODES a protein that exhibits inositol tetrakisphosphate 1-kinase activity (ortholog); inositol tetrakisphosphate 6-kinase activity (ortholog); inositol-1,3,4-trisphosphate 5-kinase activity (ortholog); INVOLVED IN necroptotic process (ortholog); neural tube development (ortholog); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; ASSOCIATED WITH achondrogenesis type IA (ortholog); genetic disease (ortholog); Neoplasm Invasiveness (ortholog); FOUND IN apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543815,107,891 - 15,257,740 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543815,107,992 - 15,257,730 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Itpk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543815,107,891 - 15,257,740 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543815,107,992 - 15,257,730 (-)NCBIChiLan1.0ChiLan1.0
ITPK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381492,936,914 - 93,115,925 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1492,936,914 - 93,116,320 (-)EnsemblGRCh38hg38GRCh38
GRCh371493,403,259 - 93,582,270 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361492,475,960 - 92,651,980 (-)NCBINCBI36Build 36hg18NCBI36
Build 341492,475,959 - 92,651,980NCBI
Celera1473,457,398 - 73,636,400 (-)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1473,584,961 - 73,762,800 (-)NCBIHuRef
CHM1_11493,341,508 - 93,520,507 (-)NCBICHM1_1
T2T-CHM13v2.01487,168,906 - 87,347,917 (-)NCBIT2T-CHM13v2.0
Itpk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912102,534,842 - 102,671,128 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12102,534,841 - 102,671,189 (-)EnsemblGRCm39 Ensembl
GRCm3812102,568,583 - 102,704,869 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12102,568,582 - 102,704,930 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712103,806,793 - 103,943,079 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612102,969,633 - 103,105,919 (-)NCBIMGSCv36mm8
Celera12103,782,829 - 103,919,411 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.69NCBI
Itpk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86127,475,589 - 127,609,320 (-)NCBIGRCr8
mRatBN7.26121,710,750 - 121,844,501 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,710,755 - 121,844,107 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6121,850,453 - 121,982,457 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,145,701 - 122,277,708 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06121,482,099 - 121,614,034 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06126,448,920 - 126,582,188 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6126,450,139 - 126,582,134 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06135,660,943 - 135,790,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46126,837,135 - 126,969,350 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6119,200,722 - 119,330,748 (-)NCBICelera
Cytogenetic Map6q32NCBI
ITPK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21594,098,055 - 94,275,927 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11493,314,561 - 93,491,649 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01473,573,020 - 73,750,109 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11492,909,785 - 93,087,773 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1492,909,785 - 93,087,773 (-)Ensemblpanpan1.1panPan2
ITPK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,976,089 - 2,136,228 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl81,977,740 - 2,136,339 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha81,979,707 - 2,159,693 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.082,012,020 - 2,191,809 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.181,947,975 - 2,127,830 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.081,898,042 - 2,078,021 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.082,025,376 - 2,205,114 (-)NCBIUU_Cfam_GSD_1.0
Itpk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864012,402,818 - 12,536,055 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936733930,972 - 1,064,229 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936733930,986 - 1,064,223 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7114,361,968 - 114,520,793 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17114,361,976 - 114,520,805 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27120,970,535 - 121,053,191 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITPK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12470,680,791 - 70,860,132 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2470,679,303 - 70,859,587 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605357,929,735 - 58,110,383 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itpk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247349,417,939 - 9,568,702 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247349,420,232 - 9,568,655 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000018235   ⟹   ENSCLAP00000018057
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543815,107,891 - 15,257,740 (-)Ensembl
RefSeq Acc Id: XM_005390340   ⟹   XP_005390397
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543815,107,992 - 15,257,727 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013517236   ⟹   XP_013372690
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543815,107,992 - 15,257,730 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013517237   ⟹   XP_013372691
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543815,107,992 - 15,200,694 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005390397 (Get FASTA)   NCBI Sequence Viewer  
  XP_013372690 (Get FASTA)   NCBI Sequence Viewer  
  XP_013372691 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018057
  ENSCLAP00000018057.1
RefSeq Acc Id: XP_005390397   ⟸   XM_005390340
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VS54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013372690   ⟸   XM_013517236
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013372691   ⟸   XM_013517237
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000018057   ⟸   ENSCLAT00000018235
Protein Domains
ATP-grasp


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012387 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018235 ENTREZGENE
  ENSCLAT00000018235.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1490.220 UniProtKB/TrEMBL
  3.40.50.11370 UniProtKB/TrEMBL
InterPro ATP-grasp UniProtKB/TrEMBL
  Inositol_tetrakis-P_1-kinase UniProtKB/TrEMBL
  InsP(3)kin_ATP-grasp UniProtKB/TrEMBL
  ITPK1_N UniProtKB/TrEMBL
NCBI Gene Itpk1 ENTREZGENE
PANTHER INOSITOL-TETRAKISPHOSPHATE 1-KINASE UniProtKB/TrEMBL
  PTHR14217 UniProtKB/TrEMBL
Pfam Ins134_P3_kin UniProtKB/TrEMBL
  Ins134_P3_kin_N UniProtKB/TrEMBL
PROSITE ATP_GRASP UniProtKB/TrEMBL
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
UniProt A0A8C2VS54 ENTREZGENE, UniProtKB/TrEMBL