Pepd (peptidase D) - Rat Genome Database

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Gene: Pepd (peptidase D) Rattus norvegicus
Analyze
Symbol: Pepd
Name: peptidase D
RGD ID: 1594571
Description: Predicted to enable proline dipeptidase activity. Predicted to be involved in negative regulation of programmed cell death and proteolysis. Predicted to act upstream of or within CARD8 inflammasome complex assembly. Human ortholog(s) of this gene implicated in prolidase deficiency. Orthologous to human PEPD (peptidase D); INTERACTS WITH 2,4-dinitrotoluene; acetamide; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: imidodipeptidase; LOC103690062; MGC95081; Pepd_mapped; peptidase D (mapped); prolidase; proline dipeptidase; X-Pro dipeptidase; xaa-Pro dipeptidase; xaa-Pro dipeptidase-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8196,673,624 - 96,818,197 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl196,673,607 - 96,818,190 (+)EnsemblGRCr8
mRatBN7.2187,536,650 - 87,681,233 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl187,536,609 - 87,681,231 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx192,940,383 - 93,078,987 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01101,406,381 - 101,544,973 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0194,698,696 - 94,837,286 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0190,820,670 - 91,285,128 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0191,957,678 - 92,027,178 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0191,925,878 - 91,947,641 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0192,392,882 - 92,416,063 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4187,421,576 - 87,547,908 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera181,897,703 - 82,034,192 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (EXP,ISO)
diisopropyl fluorophosphate  (ISO)
diuron  (EXP)
edaravone  (EXP)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
ivermectin  (ISO)
ketoconazole  (EXP)
L-ascorbic acid  (ISO)
linsidomine  (ISO)
melanins  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylparaben  (ISO)
microcystin-LR  (ISO)
monosodium L-glutamate  (ISO)
N,N-diethyl-m-toluamide  (ISO)
Nivalenol  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenacetin  (ISO)
phenobarbital  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
sarin  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Sodium salicylate  (ISO)
Soman  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
troglitazone  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
VX nerve agent  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Structural organization of the gene for human prolidase (peptidase D) and demonstration of a partial gene deletion in a patient with prolidase deficiency. Tanoue A, etal., J Biol Chem 1990 Jul 5;265(19):11306-11.
Additional References at PubMed
PMID:4187938   PMID:12477932   PMID:19056867   PMID:19782660   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Pepd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8196,673,624 - 96,818,197 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl196,673,607 - 96,818,190 (+)EnsemblGRCr8
mRatBN7.2187,536,650 - 87,681,233 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl187,536,609 - 87,681,231 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx192,940,383 - 93,078,987 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01101,406,381 - 101,544,973 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0194,698,696 - 94,837,286 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0190,820,670 - 91,285,128 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0191,957,678 - 92,027,178 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0191,925,878 - 91,947,641 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0192,392,882 - 92,416,063 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4187,421,576 - 87,547,908 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera181,897,703 - 82,034,192 (+)NCBICelera
Cytogenetic Map1q21NCBI
PEPD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381933,386,950 - 33,521,791 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1933,386,950 - 33,521,823 (-)Ensemblhg38GRCh38
GRCh371933,877,856 - 34,012,697 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361938,569,701 - 38,704,641 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341938,569,698 - 38,704,522NCBI
Celera1930,571,427 - 30,706,398 (-)NCBICelera
Cytogenetic Map19q13.11NCBI
HuRef1930,378,491 - 30,405,183 (-)NCBIHuRef
HuRef1930,454,304 - 30,512,607 (-)NCBIHuRef
CHM1_11933,878,802 - 34,013,898 (-)NCBICHM1_1
T2T-CHM13v2.01935,906,727 - 36,042,546 (-)NCBIT2T-CHM13v2.0
Pepd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39734,611,832 - 34,744,131 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl734,611,804 - 34,744,133 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38734,912,407 - 35,044,708 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl734,912,379 - 35,044,708 (+)Ensemblmm10GRCm38
MGSCv37735,697,426 - 35,829,727 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36734,615,661 - 34,753,468 (+)NCBIMGSCv36mm8
Celera730,044,756 - 30,180,582 (+)NCBICelera
Cytogenetic Map7B2NCBI
cM Map720.7NCBI
Pepd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554683,146,521 - 3,277,294 (-)Ensembl
ChiLan1.0NW_0049554683,147,871 - 3,277,294 (-)NCBIChiLan1.0ChiLan1.0
PEPD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22039,358,731 - 39,499,776 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11941,358,772 - 41,499,812 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01930,309,243 - 30,450,279 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11939,053,917 - 39,193,991 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1939,053,917 - 39,193,991 (-)EnsemblpanPan2panpan1.1
PEPD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11118,662,560 - 118,773,193 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1118,662,626 - 118,773,153 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1118,064,464 - 118,174,177 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01119,262,216 - 119,371,684 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1119,262,261 - 119,371,682 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11118,822,660 - 118,932,372 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01118,449,147 - 118,558,880 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01119,508,173 - 119,617,551 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pepd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093499,214,005 - 9,329,959 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365702,315,954 - 2,431,884 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365702,315,981 - 2,431,878 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEPD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl643,177,062 - 43,290,369 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1643,177,063 - 43,290,389 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2638,845,166 - 38,936,198 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PEPD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1628,427,940 - 28,562,554 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl628,427,912 - 28,553,316 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660736,152,349 - 6,294,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pepd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247949,602,487 - 9,724,260 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247949,602,497 - 9,724,260 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pepd
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12163,643,880 - 163,776,867 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pepd
642 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:32
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000028701
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat

Markers in Region
D1Rat189  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8196,717,367 - 96,717,567 (+)Marker Load Pipeline
mRatBN7.2187,580,395 - 87,580,595 (+)MAPPERmRatBN7.2
Rnor_6.0190,804,143 - 90,804,342NCBIRnor6.0
Rnor_6.0190,864,415 - 90,864,614NCBIRnor6.0
Rnor_5.0192,001,423 - 92,001,622UniSTSRnor5.0
Rnor_5.0191,941,720 - 91,941,919UniSTSRnor5.0
RGSC_v3.4187,465,281 - 87,465,704RGDRGSC3.4
RGSC_v3.4187,465,286 - 87,465,485UniSTSRGSC3.4
Celera181,937,065 - 81,937,264UniSTS
RGSC_v3.1187,543,397 - 87,543,596RGD
RH 3.4 Map1860.1RGD
RH 3.4 Map1860.1UniSTS
RH 2.0 Map1546.6RGD
SHRSP x BN Map143.3699RGD
FHH x ACI Map146.2899RGD
Cytogenetic Map1q21UniSTS
D1Got92  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,568,540 - 87,568,702 (+)MAPPERmRatBN7.2
Rnor_6.0190,852,562 - 90,852,723NCBIRnor6.0
Rnor_6.0190,792,290 - 90,792,451NCBIRnor6.0
Rnor_5.0191,989,570 - 91,989,731UniSTSRnor5.0
Rnor_5.0191,929,867 - 91,930,028UniSTSRnor5.0
RGSC_v3.4187,453,433 - 87,453,594UniSTSRGSC3.4
RGSC_v3.4187,453,434 - 87,453,594RGDRGSC3.4
RGSC_v3.1187,531,545 - 87,531,705RGD
RH 3.4 Map1824.6UniSTS
RH 3.4 Map1824.6RGD
RH 2.0 Map1526.6RGD
Cytogenetic Map1q21UniSTS
D1Got263  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,568,541 - 87,568,681 (+)MAPPERmRatBN7.2
Rnor_6.0190,852,563 - 90,852,702NCBIRnor6.0
Rnor_6.0190,792,291 - 90,792,430NCBIRnor6.0
Rnor_5.0191,989,571 - 91,989,710UniSTSRnor5.0
Rnor_5.0191,929,868 - 91,930,007UniSTSRnor5.0
RGSC_v3.4187,453,434 - 87,453,573RGDRGSC3.4
RGSC_v3.4187,453,434 - 87,453,573UniSTSRGSC3.4
RGSC_v3.1187,531,545 - 87,531,684RGD
Cytogenetic Map1q21UniSTS
AU048004  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,580,381 - 87,580,577 (+)MAPPERmRatBN7.2
Rnor_6.0190,864,401 - 90,864,596NCBIRnor6.0
Rnor_6.0190,804,129 - 90,804,324NCBIRnor6.0
Rnor_5.0191,941,706 - 91,941,901UniSTSRnor5.0
Rnor_5.0192,001,409 - 92,001,604UniSTSRnor5.0
RGSC_v3.4187,465,272 - 87,465,467UniSTSRGSC3.4
Celera181,937,051 - 81,937,246UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 50 67 138 95 11 49 36 32 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000077404   ⟹   ENSRNOP00000095277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl196,673,607 - 96,818,189 (+)Ensembl
mRatBN7.2 Ensembl187,536,609 - 87,681,231 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118764   ⟹   ENSRNOP00000085744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl196,681,990 - 96,818,190 (+)Ensembl
mRatBN7.2 Ensembl187,545,016 - 87,681,231 (+)Ensembl
RefSeq Acc Id: NM_001009641   ⟹   NP_001009641
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8196,673,624 - 96,818,197 (+)NCBI
mRatBN7.2187,536,650 - 87,681,233 (+)NCBI
Rnor_6.0190,820,670 - 91,285,128 (+)NCBI
Rnor_5.0191,957,678 - 92,027,178 (+)NCBI
Rnor_5.0192,392,882 - 92,416,063 (+)NCBI
RGSC_v3.4187,421,576 - 87,547,908 (+)RGD
Celera181,897,703 - 82,034,192 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009641 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88440 (Get FASTA)   NCBI Sequence Viewer  
  EDM07635 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000095277
  ENSRNOP00000095277.1
GenBank Protein Q5I0D7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009641   ⟸   NM_001009641
- UniProtKB: Q5I0D7 (UniProtKB/Swiss-Prot),   A0A8I6A0W2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000095277   ⟸   ENSRNOT00000077404
Ensembl Acc Id: ENSRNOP00000085744   ⟸   ENSRNOT00000118764
Protein Domains
Aminopeptidase P N-terminal   Peptidase M24

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5I0D7-F1-model_v2 AlphaFold Q5I0D7 1-492 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594571 AgrOrtholog
BioCyc Gene G2FUF-59999 BioCyc
Ensembl Genes ENSRNOG00000052945 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077404 ENTREZGENE
  ENSRNOT00000077404.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.350.10 UniProtKB/Swiss-Prot
  3.90.230.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7126171 IMAGE-MGC_LOAD
InterPro Aminopep_P_N UniProtKB/Swiss-Prot
  Creatin/AminoP/Spt16_NTD UniProtKB/Swiss-Prot
  Creatinase/aminopeptidase-like UniProtKB/Swiss-Prot
  Eukaryotic-type_Prolidase UniProtKB/Swiss-Prot
  Pept_M24 UniProtKB/Swiss-Prot
  Peptidase_M24B_aminopep-P_CS UniProtKB/Swiss-Prot
KEGG Report rno:292808 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95081 IMAGE-MGC_LOAD
NCBI Gene 292808 ENTREZGENE
PANTHER PEPTIDASE D UniProtKB/Swiss-Prot
  PTHR48480 UniProtKB/Swiss-Prot
Pfam AMP_N UniProtKB/Swiss-Prot
  Peptidase_M24 UniProtKB/Swiss-Prot
PhenoGen Pepd PhenoGen
PROSITE PROLINE_PEPTIDASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000052945 RatGTEx
SMART AMP_N UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53092 UniProtKB/Swiss-Prot
  SSF55920 UniProtKB/Swiss-Prot
UniProt A0A8I6A0W2 ENTREZGENE, UniProtKB/TrEMBL
  A6JA99_RAT UniProtKB/TrEMBL
  PEPD_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pepd  peptidase D  LOC103690062  xaa-Pro dipeptidase-like  Data merged from RGD:9222264 737654 PROVISIONAL
2014-08-25 LOC103690062  xaa-Pro dipeptidase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2007-04-13   peptidase D  Pepd  peptidase D (mapped)  Name updated 737654 APPROVED
2007-04-11 Pepd  peptidase D (mapped)  Pepd_mapped  peptidase D (mapped)  Data merged from RGD:3303 737654 APPROVED
2006-11-20 Pepd  peptidase D (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Pepd_mapped  peptidase D (mapped)      Symbol and Name updated 1556543 APPROVED
2002-11-06 Pepd  peptidase D    Peptidase D  Name updated 625702 APPROVED
2002-06-10 Pepd  Peptidase D      Symbol and Name status set to approved 70586 APPROVED