Pepd (peptidase D) - Rat Genome Database

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Gene: Pepd (peptidase D) Mus musculus
Analyze
Symbol: Pepd
Name: peptidase D
RGD ID: 11075
MGI Page MGI
Description: Enables peptidase activity. Predicted to be involved in negative regulation of programmed cell death and proteolysis. Predicted to act upstream of or within collagen catabolic process. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study hypertrophic cardiomyopathy. Human ortholog(s) of this gene implicated in prolidase deficiency. Orthologous to human PEPD (peptidase D).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: d; dal; imidodipeptidase; Pe; Pep; Pep-4; Pep4; peptidase 4; prolidase; proline dipeptidase; X-pro dipeptidase; xaa-Pro dipeptidase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39734,611,832 - 34,744,131 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl734,611,804 - 34,744,133 (+)EnsemblGRCm39 Ensembl
GRCm38734,912,407 - 35,044,708 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl734,912,379 - 35,044,708 (+)EnsemblGRCm38mm10GRCm38
MGSCv37735,697,426 - 35,829,727 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36734,615,661 - 34,753,468 (+)NCBIMGSCv36mm8
Celera730,044,756 - 30,180,582 (+)NCBICelera
Cytogenetic Map7B2NCBI
cM Map720.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chromium(6+)  (EXP)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cyproconazole  (EXP)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (EXP,ISO)
diisopropyl fluorophosphate  (ISO)
diuron  (ISO)
edaravone  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (EXP)
folic acid  (EXP)
genistein  (EXP)
gentamycin  (ISO)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
inulin  (EXP)
ivermectin  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (ISO)
linsidomine  (EXP)
melanins  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methylparaben  (ISO)
microcystin-LR  (EXP)
monosodium L-glutamate  (EXP)
N,N-diethyl-m-toluamide  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
ozone  (EXP,ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenacetin  (ISO)
phenobarbital  (EXP,ISO)
propiconazole  (EXP)
rac-lactic acid  (ISO)
sarin  (ISO)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
Sodium salicylate  (ISO)
Soman  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (ISO)
titanium dioxide  (EXP)
troglitazone  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
VX nerve agent  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal agouti pigmentation  (IAGP)
abnormal aorta collagen fibril morphology  (IAGP)
abnormal behavior  (IEA)
abnormal bone structure  (IEA)
abnormal cardiac muscle tissue morphology  (IAGP)
abnormal cornea morphology  (IEA)
abnormal fetal cardiomyocyte physiology  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart septum morphology  (IAGP)
abnormal joint morphology  (IEA)
abnormal myocardial fiber morphology  (IAGP)
abnormal optic disk morphology  (IEA)
abnormal retina morphology  (IEA)
abnormal seminiferous tubule morphology  (IAGP)
abnormal testis interstitial tissue morphology  (IAGP)
abnormal testis morphology  (IAGP)
abnormal urine homeostasis  (IEA)
atrioventricular septal defect  (IAGP)
brain vacuoles  (IAGP)
darkened coat color  (IAGP)
decreased B cell number  (IEA)
decreased B-2 B cell number  (IEA)
decreased body size  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IEA)
decreased CD5-positive Ly6C-positive T cell number  (IEA)
decreased circulating HDL cholesterol level  (IEA)
decreased circulating iron level  (IEA)
decreased circulating testosterone level  (IAGP)
decreased collagen level  (IAGP)
decreased follicular B cell number  (IEA)
decreased heart rate  (IEA)
decreased immature B cell number  (IEA)
decreased locomotor activity  (IEA)
decreased Ly6C-positive NK T cell number  (IEA)
decreased mean corpuscular hemoglobin  (IEA)
decreased mean corpuscular volume  (IEA)
decreased oocyte number  (IEA)
decreased transitional stage T1 B cell number  (IEA)
decreased vertical activity  (IEA)
embryonic growth retardation  (IAGP)
enlarged lymph nodes  (IEA)
hyperactivity  (IEA)
increased atrioventricular cushion size  (IAGP)
increased CD4-positive, alpha-beta T cell number  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased circulating insulin level  (IEA)
increased circulating unsaturated transferrin level  (IEA)
increased effector memory CD8-positive, alpha-beta T cell number  (IEA)
increased effector memory T-helper cell number  (IEA)
increased fetal cardiomyocyte size  (IAGP)
increased leukocyte cell number  (IEA)
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
increased memory-marker CD4-negative NK T cell number  (IEA)
increased memory-marker NK cell number  (IEA)
increased thigmotaxis  (IEA)
irregular coat pigmentation  (IEA)
myocardium hypertrophy  (IAGP)
obese  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality  (IAGP)
prolonged RR interval  (IEA)
short tibia  (IEA)
small stomach  (IEA)
small testis  (IAGP)
thick interventricular septum  (IAGP)
thick ventricular wall  (IAGP)
ventricular septal defect  (IAGP)
yellow coat color  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:662012   PMID:752544   PMID:1889815   PMID:2776480   PMID:2842249   PMID:3863747   PMID:4187938   PMID:4372544   PMID:6088946   PMID:7295293   PMID:8765744   PMID:8812484  
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15489334   PMID:15741177   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16167338   PMID:18287559   PMID:18821597   PMID:19334288   PMID:21267068   PMID:21472842   PMID:21491542   PMID:21677750   PMID:21873635   PMID:23212918   PMID:25460580   PMID:28323866  
PMID:30973865   PMID:31246278   PMID:32325033   PMID:35478031   PMID:36637239   PMID:37318951  


Genomics

Comparative Map Data
Pepd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39734,611,832 - 34,744,131 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl734,611,804 - 34,744,133 (+)EnsemblGRCm39 Ensembl
GRCm38734,912,407 - 35,044,708 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl734,912,379 - 35,044,708 (+)EnsemblGRCm38mm10GRCm38
MGSCv37735,697,426 - 35,829,727 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36734,615,661 - 34,753,468 (+)NCBIMGSCv36mm8
Celera730,044,756 - 30,180,582 (+)NCBICelera
Cytogenetic Map7B2NCBI
cM Map720.7NCBI
PEPD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381933,386,950 - 33,521,791 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1933,386,950 - 33,521,823 (-)EnsemblGRCh38hg38GRCh38
GRCh371933,877,856 - 34,012,697 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361938,569,701 - 38,704,641 (-)NCBINCBI36Build 36hg18NCBI36
Build 341938,569,698 - 38,704,522NCBI
Celera1930,571,427 - 30,706,398 (-)NCBICelera
Cytogenetic Map19q13.11NCBI
HuRef1930,378,491 - 30,405,183 (-)NCBIHuRef
HuRef1930,454,304 - 30,512,607 (-)NCBIHuRef
CHM1_11933,878,802 - 34,013,898 (-)NCBICHM1_1
T2T-CHM13v2.01935,906,727 - 36,042,546 (-)NCBIT2T-CHM13v2.0
Pepd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8196,673,624 - 96,818,197 (+)NCBIGRCr8
mRatBN7.2187,536,650 - 87,681,233 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl187,536,609 - 87,681,231 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx192,940,383 - 93,078,987 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01101,406,381 - 101,544,973 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0194,698,696 - 94,837,286 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0190,820,670 - 91,285,128 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0191,957,678 - 92,027,178 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0191,925,878 - 91,947,641 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0192,392,882 - 92,416,063 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4187,421,576 - 87,547,908 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera181,897,703 - 82,034,192 (+)NCBICelera
Cytogenetic Map1q21NCBI
Pepd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554683,146,521 - 3,277,294 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554683,147,871 - 3,277,294 (-)NCBIChiLan1.0ChiLan1.0
PEPD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22039,358,731 - 39,499,776 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11941,358,772 - 41,499,812 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01930,309,243 - 30,450,279 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11939,053,917 - 39,193,991 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1939,053,917 - 39,193,991 (-)Ensemblpanpan1.1panPan2
PEPD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11118,662,560 - 118,773,193 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1118,662,626 - 118,773,153 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1118,064,464 - 118,174,177 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01119,262,216 - 119,371,684 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1119,262,261 - 119,371,682 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11118,822,660 - 118,932,372 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01118,449,147 - 118,558,880 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01119,508,173 - 119,617,551 (+)NCBIUU_Cfam_GSD_1.0
Pepd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093499,214,005 - 9,329,959 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365702,315,954 - 2,431,884 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365702,315,981 - 2,431,878 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEPD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl643,177,062 - 43,290,369 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1643,177,063 - 43,290,389 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2638,845,166 - 38,936,198 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PEPD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1628,427,940 - 28,562,554 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl628,427,912 - 28,553,316 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660736,152,349 - 6,294,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pepd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247949,602,487 - 9,724,260 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247949,602,497 - 9,724,260 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pepd
4726 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1104
Count of miRNA genes:616
Interacting mature miRNAs:722
Transcripts:ENSMUST00000075068, ENSMUST00000160320, ENSMUST00000160459, ENSMUST00000161128, ENSMUST00000161900, ENSMUST00000162509
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
7394747asp3_maudiogenic seizure prone 3 (mouse)Not determined72730579836842367Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse

Markers in Region
U51014  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38735,044,476 - 35,044,643UniSTSGRCm38
MGSCv37735,829,495 - 35,829,662UniSTSGRCm37
Celera730,180,350 - 30,180,517UniSTS
Cytogenetic Map7B1UniSTS
cM Map715.0UniSTS
Whitehead_YAC7 UniSTS
UniSTS:235650  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38735,044,476 - 35,044,684UniSTSGRCm38
MGSCv37735,829,495 - 35,829,703UniSTSGRCm37
Celera730,180,350 - 30,180,558UniSTS
Cytogenetic Map7B1UniSTS
cM Map715.0UniSTS
D1Got263  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38734,938,519 - 34,938,628UniSTSGRCm38
MGSCv37735,723,538 - 35,723,647UniSTSGRCm37
Celera730,074,067 - 30,074,176UniSTS
Cytogenetic Map7B1UniSTS
cM Map715.0UniSTS
Pep4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38735,044,470 - 35,044,647UniSTSGRCm38
MGSCv37735,829,489 - 35,829,666UniSTSGRCm37
Celera730,180,344 - 30,180,521UniSTS
Cytogenetic Map7B1UniSTS
cM Map715.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001417082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC149058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI462142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC131945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC131973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D82983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U51014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000075068   ⟹   ENSMUSP00000075683
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl734,611,804 - 34,744,133 (+)Ensembl
GRCm38.p6 Ensembl734,912,379 - 35,044,708 (+)Ensembl
RefSeq Acc Id: ENSMUST00000160320
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl734,739,907 - 34,744,132 (+)Ensembl
GRCm38.p6 Ensembl735,040,482 - 35,044,707 (+)Ensembl
RefSeq Acc Id: ENSMUST00000160459
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl734,742,615 - 34,743,959 (+)Ensembl
GRCm38.p6 Ensembl735,043,190 - 35,044,534 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161128
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl734,668,708 - 34,740,159 (+)Ensembl
GRCm38.p6 Ensembl734,969,283 - 35,040,734 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161900   ⟹   ENSMUSP00000133634
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl734,645,014 - 34,721,171 (+)Ensembl
GRCm38.p6 Ensembl734,945,589 - 35,021,746 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162509
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl734,668,935 - 34,680,219 (+)Ensembl
GRCm38.p6 Ensembl734,969,510 - 34,980,794 (+)Ensembl
RefSeq Acc Id: NM_001417082   ⟹   NP_001404011
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39734,611,832 - 34,744,131 (+)NCBI
RefSeq Acc Id: NM_001417083   ⟹   NP_001404012
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39734,611,832 - 34,680,206 (+)NCBI
RefSeq Acc Id: NM_008820   ⟹   NP_032846
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39734,611,832 - 34,744,131 (+)NCBI
GRCm38734,912,407 - 35,044,708 (+)ENTREZGENE
MGSCv37735,697,426 - 35,829,727 (+)RGD
Celera730,044,756 - 30,180,582 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032846   ⟸   NM_008820
- Peptide Label: isoform 1
- UniProtKB: Q3TH86 (UniProtKB/Swiss-Prot),   P97735 (UniProtKB/Swiss-Prot),   Q9CWK4 (UniProtKB/Swiss-Prot),   Q11136 (UniProtKB/Swiss-Prot),   A2RS23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000075683   ⟸   ENSMUST00000075068
RefSeq Acc Id: ENSMUSP00000133634   ⟸   ENSMUST00000161900
RefSeq Acc Id: NP_001404011   ⟸   NM_001417082
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001404012   ⟸   NM_001417083
- Peptide Label: isoform 3
Protein Domains
Aminopeptidase P N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q11136-F1-model_v2 AlphaFold Q11136 1-493 view protein structure

Promoters
RGD ID:8663645
Promoter ID:EPDNEW_M9854
Type:multiple initiation site
Name:Pepd_1
Description:Mus musculus peptidase D , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38734,912,409 - 34,912,469EPDNEW
RGD ID:6841729
Promoter ID:MM_KWN:50006
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000078912
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36735,697,269 - 35,697,769 (+)MPROMDB
RGD ID:6841730
Promoter ID:MM_KWN:50011
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000078981
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36735,824,546 - 35,825,922 (+)MPROMDB
RGD ID:6841728
Promoter ID:MM_KWN:50012
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000078982
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36735,827,266 - 35,828,682 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97542 AgrOrtholog
Ensembl Genes ENSMUSG00000063931 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000075068 ENTREZGENE
  ENSMUST00000075068.14 UniProtKB/Swiss-Prot
  ENSMUST00000161900.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.350.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.230.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aminopep_P_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Creatin/AminoP/Spt16_NTD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Creatinase/aminopeptidase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M24B_aminopep-P_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18624 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97542 ENTREZGENE
NCBI Gene 18624 ENTREZGENE
PANTHER PEPTIDASE D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR48392 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AMP_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pepd PhenoGen
PROSITE PROLINE_PEPTIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AMP_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53092 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2RS23 ENTREZGENE, UniProtKB/TrEMBL
  G3UXC5_MOUSE UniProtKB/TrEMBL
  P97735 ENTREZGENE
  PEPD_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TH86 ENTREZGENE
  Q9CWK4 ENTREZGENE
UniProt Secondary P97735 UniProtKB/Swiss-Prot
  Q3TH86 UniProtKB/Swiss-Prot
  Q9CWK4 UniProtKB/Swiss-Prot