Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | o and p'-DDT results in decreased expression of MANSC1 mRNA | CTD | PMID:19371625 | 1,2-dimethylhydrazine | multiple interactions | ISO | Mansc1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MANSC1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Mansc1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of MANSC1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of MANSC1 mRNA | CTD | PMID:20106945 | 17beta-estradiol | multiple interactions | ISO | MANSC1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of MANSC1 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MANSC1 mRNA | CTD | PMID:20106945 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mansc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MANSC1 mRNA | CTD | PMID:21570461 and PMID:26377647 | 2-hydroxypropanoic acid | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of MANSC1 mRNA | CTD | PMID:30851411 | 2-palmitoylglycerol | increases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of MANSC1 mRNA | CTD | PMID:37199045 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of MANSC1 mRNA | CTD | PMID:24780913 | acrylamide | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of MANSC1 mRNA | CTD | PMID:32763439 | all-trans-retinoic acid | increases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of MANSC1 mRNA | CTD | PMID:21934132 and PMID:33167477 | benzo[a]pyrene | increases expression | ISO | Mansc1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of MANSC1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases methylation | ISO | MANSC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MANSC1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MANSC1 mRNA | CTD | PMID:20064835 and PMID:21632981 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MANSC1 mRNA | CTD | PMID:25181051 | cadmium atom | multiple interactions | ISO | MANSC1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MANSC1 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | MANSC1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MANSC1 mRNA | CTD | PMID:35301059 | carbon nanotube | decreases expression | ISO | Mansc1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of MANSC1 mRNA | CTD | PMID:25620056 | chlordecone | decreases expression | ISO | Mansc1 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of MANSC1 mRNA | CTD | PMID:33711761 | chlorpyrifos | increases expression | ISO | Mansc1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of MANSC1 mRNA | CTD | PMID:37019170 | choline | multiple interactions | ISO | Mansc1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MANSC1 mRNA | CTD | PMID:20938992 | cisplatin | multiple interactions | ISO | MANSC1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of MANSC1 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of MANSC1 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of MANSC1 mRNA | CTD | PMID:24386269 | cobalt dichloride | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of MANSC1 mRNA | CTD | PMID:19320972 and PMID:19376846 | copper(II) sulfate | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of MANSC1 mRNA | CTD | PMID:19549813 | doxorubicin | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MANSC1 mRNA | CTD | PMID:29803840 | entinostat | increases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | entinostat results in increased expression of MANSC1 mRNA | CTD | PMID:27188386 | folic acid | multiple interactions | ISO | Mansc1 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | FR900359 | decreases phosphorylation | ISO | MANSC1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of MANSC1 protein | CTD | PMID:37730182 | inulin | multiple interactions | ISO | Mansc1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of MANSC1 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of MANSC1 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Mansc1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MANSC1 mRNA | CTD | PMID:20938992 | Licochalcone B | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | licochalcone B results in decreased expression of MANSC1 mRNA | CTD | PMID:33647349 | lipopolysaccharide | multiple interactions | ISO | MANSC1 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | lipopolysaccharide | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of MANSC1 mRNA | CTD | PMID:35811015 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of MANSC1 gene | CTD | PMID:35440735 | methylmercury chloride | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of MANSC1 mRNA | CTD | PMID:28001369 | N-nitrosodiethylamine | increases expression | ISO | Mansc1 (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of MANSC1 mRNA | CTD | PMID:24535843 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of MANSC1 mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MANSC1 mRNA | CTD | PMID:21420995 | paracetamol | increases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MANSC1 mRNA | CTD | PMID:22230336 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of MANSC1 mRNA | CTD | PMID:32680482 | perfluorohexanesulfonic acid | increases expression | ISO | Mansc1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of MANSC1 mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Mansc1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of MANSC1 mRNA | CTD | PMID:36331819 | phenobarbital | multiple interactions | ISO | Mansc1 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of MANSC1 mRNA] | CTD | PMID:19482888 | phenobarbital | decreases expression | ISO | Mansc1 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of MANSC1 mRNA | CTD | PMID:19482888 | potassium chromate | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of MANSC1 mRNA | CTD | PMID:22714537 | quercetin | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of MANSC1 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of MANSC1 mRNA | CTD | PMID:30851411 | resveratrol | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | resveratrol results in decreased expression of MANSC1 mRNA | CTD | PMID:19371625 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | MANSC1 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | silicon dioxide | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of MANSC1 mRNA | CTD | PMID:25895662 | sodium arsenite | affects expression | ISO | MANSC1 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of MANSC1 mRNA | CTD | PMID:29319823 and PMID:34032870 | sunitinib | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of MANSC1 mRNA | CTD | PMID:31533062 | tert-butyl hydroperoxide | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of MANSC1 mRNA | CTD | PMID:15336504 | thimerosal | decreases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of MANSC1 mRNA | CTD | PMID:27188386 | titanium dioxide | increases expression | ISO | Mansc1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of MANSC1 mRNA | CTD | PMID:23557971 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of MANSC1 mRNA | CTD | PMID:25729387 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of MANSC1 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of MANSC1 mRNA | CTD | PMID:24935251 | tris(2-butoxyethyl) phosphate | affects expression | ISO | MANSC1 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of MANSC1 mRNA | CTD | PMID:29024780 | valproic acid | affects expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MANSC1 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | MANSC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MANSC1 mRNA | CTD | PMID:23179753 more ... | |