Znrf1 (zinc and ring finger 1) - Rat Genome Database

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Gene: Znrf1 (zinc and ring finger 1) Rattus norvegicus
Analyze
Symbol: Znrf1
Name: zinc and ring finger 1
RGD ID: 1592195
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including positive regulation of autophagosome-lysosome fusion; positive regulation of toll-like receptor 4 signaling pathway; and protein K48-linked ubiquitination. Predicted to act upstream of or within regulation of innate immune response. Predicted to be located in cytosol. Predicted to be active in cytoplasm and membrane. Orthologous to human ZNRF1 (zinc and ring finger 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase ZNRF1; LOC690769; similar to zinc ring finger protein 1; zinc and ring finger 1, E3 ubiquitin protein ligase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81956,403,816 - 56,490,901 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1956,405,728 - 56,490,881 (+)EnsemblGRCr8
mRatBN7.21939,496,414 - 39,581,600 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1939,496,527 - 39,580,969 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1946,296,356 - 46,380,722 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,949,689 - 47,034,049 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01949,254,321 - 49,338,675 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01943,750,205 - 43,834,962 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1943,750,278 - 43,832,878 (+)Ensemblrn6Rnor6.0
Rnor_5.01954,557,442 - 54,642,129 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41941,455,386 - 41,537,955 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1938,875,649 - 38,959,752 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA,ISO)
endosome  (IEA,ISO)
lysosome  (IEA)
membrane  (IBA,IEA,ISO)
synaptic vesicle membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19028597   PMID:22057101   PMID:22797923  


Genomics

Comparative Map Data
Znrf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81956,403,816 - 56,490,901 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1956,405,728 - 56,490,881 (+)EnsemblGRCr8
mRatBN7.21939,496,414 - 39,581,600 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1939,496,527 - 39,580,969 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1946,296,356 - 46,380,722 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,949,689 - 47,034,049 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01949,254,321 - 49,338,675 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01943,750,205 - 43,834,962 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1943,750,278 - 43,832,878 (+)Ensemblrn6Rnor6.0
Rnor_5.01954,557,442 - 54,642,129 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41941,455,386 - 41,537,955 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1938,875,649 - 38,959,752 (+)NCBICelera
Cytogenetic Map19q12NCBI
ZNRF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381674,999,024 - 75,110,994 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1674,999,014 - 75,110,994 (+)Ensemblhg38GRCh38
GRCh371675,032,922 - 75,144,892 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361673,590,416 - 73,702,393 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341673,590,415 - 73,702,393NCBI
Celera1659,325,881 - 59,437,794 (+)NCBICelera
Cytogenetic Map16q23.1NCBI
HuRef1660,784,212 - 60,895,817 (+)NCBIHuRef
CHM1_11676,445,151 - 76,557,062 (+)NCBICHM1_1
T2T-CHM13v2.01681,045,795 - 81,157,694 (+)NCBIT2T-CHM13v2.0
Znrf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398112,262,652 - 112,352,352 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8112,262,729 - 112,352,662 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388111,536,484 - 111,625,720 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8111,536,097 - 111,626,030 (+)Ensemblmm10GRCm38
MGSCv378114,060,540 - 114,149,930 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368114,423,515 - 114,510,451 (+)NCBIMGSCv36mm8
Celera8115,764,236 - 115,853,550 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map857.98NCBI
Znrf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554842,468,392 - 2,566,539 (-)Ensembl
ChiLan1.0NW_0049554842,468,392 - 2,566,539 (-)NCBIChiLan1.0ChiLan1.0
ZNRF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21884,716,474 - 84,828,132 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11690,638,445 - 90,750,117 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01655,567,875 - 55,679,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11674,920,141 - 75,030,933 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1674,920,141 - 75,030,933 (+)EnsemblpanPan2panpan1.1
ZNRF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1575,594,465 - 75,698,164 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl575,595,200 - 75,698,170 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha575,570,792 - 75,674,762 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0575,950,710 - 76,054,735 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl575,951,488 - 76,054,338 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1575,855,151 - 75,958,882 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0575,677,829 - 75,781,679 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0576,170,074 - 76,273,880 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Znrf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934935,670,243 - 35,774,914 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647523,814,194 - 23,916,530 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647523,814,200 - 23,918,871 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNRF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1612,555,655 - 12,668,807 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2612,430,136 - 12,432,305 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNRF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1560,568,582 - 60,590,699 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604715,469,480 - 15,585,200 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znrf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474611,848,425 - 11,954,784 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474611,847,627 - 11,954,637 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Znrf1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11731,222,687 - 31,308,863 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Znrf1
48 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:283
Count of miRNA genes:101
Interacting mature miRNAs:106
Transcripts:ENSRNOT00000025716, ENSRNOT00000051594, ENSRNOT00000072229
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
RH142539  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81956,454,048 - 56,454,149 (+)Marker Load Pipeline
mRatBN7.21939,544,740 - 39,544,841 (+)MAPPERmRatBN7.2
Rnor_6.01943,798,114 - 43,798,214NCBIRnor6.0
Rnor_5.01954,605,283 - 54,605,383UniSTSRnor5.0
RGSC_v3.41941,503,234 - 41,503,334UniSTSRGSC3.4
Celera1938,923,816 - 38,923,916UniSTS
RH 3.4 Map19473.2UniSTS
Cytogenetic Map19q12UniSTS
RH142554  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81956,490,567 - 56,490,801 (+)Marker Load Pipeline
mRatBN7.21939,581,269 - 39,581,503 (+)MAPPERmRatBN7.2
Rnor_6.01943,834,632 - 43,834,865NCBIRnor6.0
Rnor_5.01954,641,799 - 54,642,032UniSTSRnor5.0
RGSC_v3.41941,539,691 - 41,539,924UniSTSRGSC3.4
Celera1938,959,422 - 38,959,655UniSTS
RH 3.4 Map19485.8UniSTS
Cytogenetic Map19q12UniSTS
RH143381  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21939,581,034 - 39,581,227 (+)MAPPERmRatBN7.2
Rnor_6.01943,834,397 - 43,834,589NCBIRnor6.0
Rnor_5.01954,641,564 - 54,641,756UniSTSRnor5.0
RGSC_v3.41941,539,456 - 41,539,648UniSTSRGSC3.4
Celera1938,959,187 - 38,959,379UniSTS
RH 3.4 Map19486.8UniSTS
Cytogenetic Map19q12UniSTS
BF411716  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21939,497,975 - 39,498,074 (+)MAPPERmRatBN7.2
Rnor_6.01943,751,354 - 43,751,452NCBIRnor6.0
Rnor_5.01954,558,467 - 54,558,565UniSTSRnor5.0
RGSC_v3.41941,456,312 - 41,456,410UniSTSRGSC3.4
Celera1938,877,161 - 38,877,259UniSTS
RH 3.4 Map19487.2UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001401079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_002725417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006222748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006222749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006222750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006222751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000025716   ⟹   ENSRNOP00000025716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1956,405,775 - 56,490,261 (+)Ensembl
mRatBN7.2 Ensembl1939,497,050 - 39,580,969 (+)Ensembl
Rnor_6.0 Ensembl1943,750,278 - 43,832,878 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095580   ⟹   ENSRNOP00000093092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1956,405,728 - 56,490,881 (+)Ensembl
mRatBN7.2 Ensembl1939,496,872 - 39,578,073 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117072   ⟹   ENSRNOP00000083192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1956,405,772 - 56,490,270 (+)Ensembl
mRatBN7.2 Ensembl1939,496,527 - 39,580,969 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000167326   ⟹   ENSRNOP00000108595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1956,406,364 - 56,490,881 (+)Ensembl
RefSeq Acc Id: NM_001401079   ⟹   NP_001388008
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,405,728 - 56,490,898 (+)NCBI
mRatBN7.21939,496,414 - 39,581,600 (+)NCBI
RefSeq Acc Id: NM_001401080   ⟹   NP_001388009
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,405,728 - 56,490,898 (+)NCBI
mRatBN7.21939,496,414 - 39,581,600 (+)NCBI
RefSeq Acc Id: XM_006255650   ⟹   XP_006255712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,490,901 (+)NCBI
mRatBN7.21939,496,886 - 39,581,600 (+)NCBI
Rnor_6.01943,750,205 - 43,834,962 (+)NCBI
Rnor_5.01954,557,442 - 54,642,129 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006255651   ⟹   XP_006255713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,490,901 (+)NCBI
mRatBN7.21939,496,886 - 39,581,600 (+)NCBI
Rnor_6.01943,750,205 - 43,834,962 (+)NCBI
Rnor_5.01954,557,442 - 54,642,129 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006255652   ⟹   XP_006255714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,490,901 (+)NCBI
mRatBN7.21939,496,886 - 39,581,600 (+)NCBI
Rnor_6.01943,750,205 - 43,834,962 (+)NCBI
Rnor_5.01954,557,442 - 54,642,129 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098265   ⟹   XP_038954193
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,490,901 (+)NCBI
mRatBN7.21939,496,886 - 39,581,600 (+)NCBI
RefSeq Acc Id: XM_039098266   ⟹   XP_038954194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,486,550 (+)NCBI
mRatBN7.21939,496,886 - 39,577,251 (+)NCBI
RefSeq Acc Id: XM_039098267   ⟹   XP_038954195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,423,298 (+)NCBI
mRatBN7.21939,496,886 - 39,512,794 (+)NCBI
RefSeq Acc Id: XM_039098268   ⟹   XP_038954196
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,477,690 (+)NCBI
mRatBN7.21939,496,886 - 39,564,788 (+)NCBI
RefSeq Acc Id: XM_063278295   ⟹   XP_063134365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,490,901 (+)NCBI
RefSeq Acc Id: XM_063278296   ⟹   XP_063134366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,403,816 - 56,490,901 (+)NCBI
RefSeq Acc Id: XM_063278297   ⟹   XP_063134367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81956,424,490 - 56,490,901 (+)NCBI
RefSeq Acc Id: XP_006255712   ⟸   XM_006255650
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255714   ⟸   XM_006255652
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255713   ⟸   XM_006255651
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUZ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025716   ⟸   ENSRNOT00000025716
RefSeq Acc Id: XP_038954193   ⟸   XM_039098265
- Peptide Label: isoform X2
- UniProtKB: A6IZ93 (UniProtKB/TrEMBL),   D3ZIQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954194   ⟸   XM_039098266
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038954196   ⟸   XM_039098268
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038954195   ⟸   XM_039098267
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000083192   ⟸   ENSRNOT00000117072
Ensembl Acc Id: ENSRNOP00000093092   ⟸   ENSRNOT00000095580
RefSeq Acc Id: NP_001388008   ⟸   NM_001401079
- UniProtKB: A6IZ93 (UniProtKB/TrEMBL),   D3ZIQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388009   ⟸   NM_001401080
- UniProtKB: A6IZ93 (UniProtKB/TrEMBL),   D3ZIQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134365   ⟸   XM_063278295
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134366   ⟸   XM_063278296
- Peptide Label: isoform X2
- UniProtKB: A6IZ93 (UniProtKB/TrEMBL),   D3ZIQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134367   ⟸   XM_063278297
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000108595   ⟸   ENSRNOT00000167326
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIQ9-F1-model_v2 AlphaFold D3ZIQ9 1-227 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701160
Promoter ID:EPDNEW_R11673
Type:single initiation site
Name:Znrf1_1
Description:zinc and ring finger 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01943,750,273 - 43,750,333EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1592195 AgrOrtholog
BioCyc Gene G2FUF-5646 BioCyc
Ensembl Genes ENSRNOG00000019028 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025716.8 UniProtKB/TrEMBL
  ENSRNOT00000095580 ENTREZGENE
  ENSRNOT00000095580.2 UniProtKB/TrEMBL
  ENSRNOT00000117072 ENTREZGENE
  ENSRNOT00000117072.2 UniProtKB/TrEMBL
  ENSRNOT00000167326.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  ZNRF_ubiq-protein_ligase UniProtKB/TrEMBL
NCBI Gene 690769 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN UniProtKB/TrEMBL
Pfam zf-RING_2 UniProtKB/TrEMBL
PhenoGen Znrf1 PhenoGen
PROSITE ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019028 RatGTEx
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8I5ZUZ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGK9_RAT UniProtKB/TrEMBL
  A0ABK0LTJ3_RAT UniProtKB/TrEMBL
  A6IZ93 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIQ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-18 Znrf1  zinc and ring finger 1  Znrf1  zinc and ring finger 1, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-02 Znrf1  zinc and ring finger 1, E3 ubiquitin protein ligase  LOC690769  similar to zinc ring finger protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC690769  similar to zinc ring finger protein 1  LOC687239  similar to zinc ring finger protein 1  Data merged from RGD:1587739 1643240 APPROVED
2006-11-20 LOC690769  similar to zinc ring finger protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC687239  similar to zinc ring finger protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL