Eif5b-ps1 (eukaryotic translation initiation factor 5B, pseudogene 1) - Rat Genome Database

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Gene: Eif5b-ps1 (eukaryotic translation initiation factor 5B, pseudogene 1) Rattus norvegicus
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Symbol: Eif5b-ps1
Name: eukaryotic translation initiation factor 5B, pseudogene 1
RGD ID: 1591046
Description: ENCODES a pseudogene that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN translation (inferred); translational initiation (inferred); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride; cocaine
Type: pseudo
RefSeq Status: INFERRED
Previously known as: LOC689581; similar to Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2)
Related Functional Gene: Eif5b  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81952,297,623 - 52,301,730 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.21935,387,899 - 35,392,006 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1942,203,330 - 42,207,437 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01942,856,690 - 42,860,797 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.01938,340,738 - 38,344,845 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01949,210,431 - 49,214,538 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41937,343,402 - 37,347,524 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1934,810,100 - 34,814,207 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8667030   PMID:12477932  


Genomics

Variants

.
Variants in Eif5b-ps1
25 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat

Markers in Region
RH129308  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1934,813,948 - 34,814,132UniSTS
Celera938,029,562 - 38,029,746UniSTS
Cytogenetic Map9q21UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_028300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Protein Sequences
Ensembl Protein ENSRNOP00000103497.1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-5756 BioCyc
Ensembl Genes ENSRNOG00000085662 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000159518.1 UniProtKB/TrEMBL
NCBI Gene 689581 ENTREZGENE
PhenoGen Eif5b-ps1 PhenoGen
RatGTEx ENSRNOG00000085662 RatGTEx
UniProt A0ABK0LGL1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-08 Eif5b-ps1  eukaryotic translation initiation factor 5B, pseudogene 1  LOC689581  similar to Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC689581  similar to Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2)  LOC686553  similar to Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2)  Data merged from RGD:1596345 1643240 APPROVED
2006-11-20 LOC689581  similar to Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC686553  similar to Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2)      Symbol and Name status set to provisional 70820 PROVISIONAL