Nrg4 (neuregulin 4) - Rat Genome Database

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Gene: Nrg4 (neuregulin 4) Rattus norvegicus
Analyze
Symbol: Nrg4
Name: neuregulin 4
RGD ID: 1589860
Description: Predicted to enable receptor ligand activity. Predicted to be involved in ERBB4-ERBB4 signaling pathway. Predicted to be located in membrane. Predicted to be active in extracellular space. Orthologous to human NRG4 (neuregulin 4); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC690919; pro-neuregulin-4, membrane-bound isoform; similar to neuregulin 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8864,483,559 - 64,555,671 (-)NCBIGRCr8
mRatBN7.2855,586,253 - 55,677,829 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl855,592,893 - 55,677,483 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx861,134,880 - 61,200,698 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0859,413,879 - 59,479,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0857,278,120 - 57,343,934 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0859,782,789 - 59,849,433 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl859,782,974 - 59,849,490 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0858,364,273 - 58,430,812 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4858,764,526 - 58,830,666 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera855,077,998 - 55,144,113 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nrg4RatBloom syndrome  ISONRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: Bloom syndromeClinVarPMID:28492532
Nrg4Ratcolorectal cancer  ISONRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:28492532
Nrg4RatPAPA syndrome  ISONRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: PAPA SYNDROMEClinVarPMID:28492532
Nrg4Ratschizophrenia  ISONRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311

1 to 20 of 68 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nrg4Rat(1->4)-beta-D-glucan multiple interactionsISONrg4 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of NRG4 mRNACTDPMID:36331819
Nrg4Rat(2,4,5-trichlorophenoxy)acetic acid decreases expressionISONrg4 (Mus musculus)64804642 more ...CTDPMID:18579281
Nrg4Rat1,2-dichloroethane decreases expressionISONrg4 (Mus musculus)6480464ethylene dichloride results in decreased expression of NRG4 mRNACTDPMID:28960355
Nrg4Rat1,2-dimethylhydrazine decreases expressionISONrg4 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of NRG4 mRNACTDPMID:22206623
Nrg4Rat17beta-estradiol decreases expressionISONrg4 (Mus musculus)6480464Estradiol results in decreased expression of NRG4 mRNACTDPMID:19693291 and PMID:39298647
Nrg4Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONrg4 (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of NRG4 mRNA and AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NRG4 mRNA]CTDPMID:16214954 and PMID:25975270
Nrg4Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONrg4 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NRG4 mRNACTDPMID:28922406
Nrg4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of NRG4 mRNACTDPMID:21215274
Nrg4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISONrg4 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of NRG4 mRNACTDPMID:19770486
Nrg4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISONrg4 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of NRG4 mRNACTDPMID:16214954
Nrg4Rat2-palmitoylglycerol increases expressionISONRG4 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of NRG4 mRNACTDPMID:37199045
Nrg4Rat3,3',4,4'-tetrachlorobiphenyl multiple interactionsISONrg4 (Mus musculus)64804643 more ...CTDPMID:19467301
Nrg4Rat4,4'-diaminodiphenylmethane decreases expressionISONrg4 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of NRG4 mRNACTDPMID:18648102
Nrg4Rat4,4'-sulfonyldiphenol affects expressionISONrg4 (Mus musculus)6480464bisphenol S affects the expression of NRG4 mRNACTDPMID:39298647
Nrg4Rat4,4'-sulfonyldiphenol decreases expressionISONrg4 (Mus musculus)6480464bisphenol S results in decreased expression of NRG4 mRNACTDPMID:33297965
Nrg4Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of NRG4 mRNACTDPMID:31881176
Nrg4Ratacrylamide increases expressionISONrg4 (Mus musculus)6480464Acrylamide results in increased expression of NRG4 mRNACTDPMID:30807115
Nrg4Rataflatoxin B1 increases expressionISONrg4 (Mus musculus)6480464Aflatoxin B1 results in increased expression of NRG4 mRNACTDPMID:19770486
Nrg4Rataldrin decreases expressionISONrg4 (Mus musculus)6480464Aldrin results in decreased expression of NRG4 mRNACTDPMID:18579281
Nrg4Ratamphetamine increases expressionEXP 6480464Amphetamine results in increased expression of NRG4 mRNACTDPMID:30779732

1 to 20 of 68 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nrg4Ratbiological_process  ND 159840705/10: no relevant rat dataRGD 
Nrg4RatERBB4-ERBB4 signaling pathway involved_inISONrg4 (Mus musculus)1624291UniProtKB:Q15303 and PMID:12466964RGDPMID:12466964

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nrg4Ratextracellular space is_active_inISONrg4 (Mus musculus)1624291UniProtKB:Q15303 and PMID:12466964RGDPMID:12466964
Nrg4Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Nrg4Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nrg4Ratepidermal growth factor/neuregulin signaling pathway   ISONRG4 (Homo sapiens)2317965 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nrg4Ratepidermal growth factor/neuregulin signaling pathway   IEA 6907045 KEGGrno:04012

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nrg4Ratepidermal growth factor/neuregulin signaling pathway   ISONRG4 (Homo sapiens)6484113 PIDPID:200159

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Localization of HRG4, a photoreceptor protein homologous to Unc-119, in ribbon synapse. Higashide T, etal., Invest Ophthalmol Vis Sci. 1998 Apr;39(5):690-8.
3. Neuregulins and cancer. Montero JC, etal., Clin Cancer Res. 2008 Jun 1;14(11):3237-41. doi: 10.1158/1078-0432.CCR-07-5133.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:12466964   PMID:35809324   PMID:37614134   PMID:38465779  



Nrg4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8864,483,559 - 64,555,671 (-)NCBIGRCr8
mRatBN7.2855,586,253 - 55,677,829 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl855,592,893 - 55,677,483 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx861,134,880 - 61,200,698 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0859,413,879 - 59,479,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0857,278,120 - 57,343,934 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0859,782,789 - 59,849,433 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl859,782,974 - 59,849,490 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0858,364,273 - 58,430,812 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4858,764,526 - 58,830,666 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera855,077,998 - 55,144,113 (-)NCBICelera
Cytogenetic Map8q24NCBI
NRG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381575,935,393 - 76,060,240 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1575,935,969 - 76,059,795 (-)EnsemblGRCh38hg38GRCh38
GRCh371576,233,277 - 76,304,765 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361574,022,899 - 74,091,842 (-)NCBINCBI36Build 36hg18NCBI36
Celera1553,160,233 - 53,230,688 (-)NCBICelera
Cytogenetic Map15q24.2NCBI
HuRef1552,990,494 - 53,060,953 (-)NCBIHuRef
CHM1_11576,353,787 - 76,424,243 (-)NCBICHM1_1
T2T-CHM13v2.01573,806,132 - 73,930,956 (-)NCBIT2T-CHM13v2.0
Nrg4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39955,127,506 - 55,190,937 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl955,127,506 - 55,234,128 (-)EnsemblGRCm39 Ensembl
GRCm38955,220,222 - 55,283,654 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl955,220,222 - 55,326,844 (-)EnsemblGRCm38mm10GRCm38
MGSCv37955,068,029 - 55,131,432 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36955,019,438 - 55,081,640 (-)NCBIMGSCv36mm8
Celera952,459,910 - 52,522,742 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map929.87NCBI
Nrg4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554501,174,131 - 1,243,059 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554501,174,131 - 1,243,040 (-)NCBIChiLan1.0ChiLan1.0
NRG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21665,133,478 - 65,256,981 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11569,297,612 - 69,421,101 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01554,849,104 - 54,972,379 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11574,442,017 - 74,518,748 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1574,449,691 - 74,518,748 (-)Ensemblpanpan1.1panPan2
NRG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1297,478,483 - 7,483,875 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha297,788,011 - 7,796,554 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0297,549,606 - 7,558,147 (+)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.0297,695,845 - 7,704,388 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0297,972,712 - 7,981,255 (+)NCBIUU_Cfam_GSD_1.0
Nrg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640118,215,219 - 118,396,897 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647136,134,061 - 36,240,711 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647136,062,579 - 36,240,613 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl756,167,959 - 56,311,270 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1756,179,713 - 56,311,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2760,748,823 - 60,869,902 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NRG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1267,232,141 - 7,355,637 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl267,276,818 - 7,347,514 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048134,358,412 - 134,483,926 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nrg4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248942,087,302 - 2,158,167 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248942,057,477 - 2,167,321 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Nrg4
574 total Variants

Predicted Target Of
Summary Value
Count of predictions:195
Count of miRNA genes:149
Interacting mature miRNAs:167
Transcripts:ENSRNOT00000020332
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 60 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat

1 to 10 of 60 rows
RH130623  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2855,595,538 - 55,595,740 (+)MAPPERmRatBN7.2
Rnor_6.0859,785,619 - 59,785,820NCBIRnor6.0
Rnor_5.0858,366,918 - 58,367,119UniSTSRnor5.0
RGSC_v3.4858,767,171 - 58,767,372UniSTSRGSC3.4
Celera855,080,643 - 55,080,844UniSTS
RH 3.4 Map8629.2UniSTS
Cytogenetic Map8q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 29 90 85 84 53 25 53 6 173 75 70 28 55 31



Ensembl Acc Id: ENSRNOT00000020332   ⟹   ENSRNOP00000020332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl855,592,893 - 55,677,483 (-)Ensembl
Rnor_6.0 Ensembl859,782,974 - 59,849,427 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083900   ⟹   ENSRNOP00000070605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl859,791,687 - 59,849,490 (-)Ensembl
RefSeq Acc Id: NM_001191109   ⟹   NP_001178038
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8864,488,722 - 64,555,173 (-)NCBI
mRatBN7.2855,592,893 - 55,659,014 (-)NCBI
Rnor_6.0859,782,974 - 59,849,433 (-)NCBI
Rnor_5.0858,364,273 - 58,430,812 (-)NCBI
Celera855,077,998 - 55,144,113 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039082177   ⟹   XP_038938105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8864,483,559 - 64,554,055 (-)NCBI
mRatBN7.2855,586,253 - 55,659,493 (-)NCBI
RefSeq Acc Id: XM_039082178   ⟹   XP_038938106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8864,494,850 - 64,554,055 (-)NCBI
mRatBN7.2855,598,435 - 55,659,493 (-)NCBI
RefSeq Acc Id: XM_063266172   ⟹   XP_063122242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8864,488,790 - 64,554,053 (-)NCBI
RefSeq Acc Id: XM_063266173   ⟹   XP_063122243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8864,494,617 - 64,554,055 (-)NCBI
RefSeq Acc Id: XM_063266174   ⟹   XP_063122244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8864,488,790 - 64,555,671 (-)NCBI
RefSeq Acc Id: XM_063266175   ⟹   XP_063122245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8864,488,790 - 64,555,550 (-)NCBI
RefSeq Acc Id: NP_001178038   ⟸   NM_001191109
- UniProtKB: A6J4P4 (UniProtKB/TrEMBL),   F1M0L6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020332   ⟸   ENSRNOT00000020332
Ensembl Acc Id: ENSRNOP00000070605   ⟸   ENSRNOT00000083900
RefSeq Acc Id: XP_038938105   ⟸   XM_039082177
- Peptide Label: isoform X1
- UniProtKB: F1M0L6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938106   ⟸   XM_039082178
- Peptide Label: isoform X1
- UniProtKB: F1M0L6 (UniProtKB/TrEMBL)
EGF-like

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JYC9-F1-model_v2 AlphaFold A0A0G2JYC9 1-115 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-30376 BioCyc
Ensembl Genes ENSRNOG00000015149 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020332.6 UniProtKB/TrEMBL
  ENSRNOT00000128207 ENTREZGENE
  ENSRNOT00000132390 ENTREZGENE
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro EG-like_dom UniProtKB/TrEMBL
KEGG Report rno:690919 UniProtKB/TrEMBL
NCBI Gene 690919 ENTREZGENE
PANTHER EPIGEN UniProtKB/TrEMBL
  TRANSFORMING GROWTH FACTOR ALPHA UniProtKB/TrEMBL
PhenoGen Nrg4 PhenoGen
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015149 RatGTEx
SMART EGF UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
UniProt A6J4P4 ENTREZGENE, UniProtKB/TrEMBL
  F1M0L6 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Nrg4  neuregulin 4  LOC690919  similar to neuregulin 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC690919  similar to neuregulin 4  LOC686216  similar to neuregulin 4  Data merged from RGD:1584347 1643240 APPROVED
2006-11-20 LOC690919  similar to neuregulin 4      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC686216  similar to neuregulin 4      Symbol and Name status set to provisional 70820 PROVISIONAL