B3glct (beta 3-glucosyltransferase) - Rat Genome Database

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Gene: B3glct (beta 3-glucosyltransferase) Rattus norvegicus
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Symbol: B3glct
Name: beta 3-glucosyltransferase
RGD ID: 1588723
Description: Predicted to enable acetylglucosaminyltransferase activity. Predicted to be involved in fucose metabolic process. Predicted to act upstream of or within several processes, including cilium assembly; protein O-linked glycosylation via fucose; and protein secretion. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Peters plus syndrome. Orthologous to human B3GLCT (beta 3-glucosyltransferase); INTERACTS WITH glyphosate; vinclozolin; (-)-demecolcine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B3galtl; B3galtl-ps1; beta 1,3-galactosyltransferase-like; beta 1,3-galactosyltransferase-like, pseudogene 1; beta-1,3-glucosyltransferase; LOC689765; similar to beta 3-glycosyltransferase-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,291,910 - 10,383,190 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1210,291,910 - 10,426,357 (-)EnsemblGRCr8
mRatBN7.2125,255,521 - 5,346,807 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl125,255,740 - 5,346,810 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx125,940,750 - 6,024,322 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0126,564,180 - 6,647,748 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0125,591,696 - 5,675,262 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0126,403,118 - 6,476,010 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl126,403,940 - 6,473,321 (+)Ensemblrn6Rnor6.0
Rnor_5.0128,485,545 - 8,576,783 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4125,695,579 - 5,706,396 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera127,034,312 - 7,117,929 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
B3glct
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,291,910 - 10,383,190 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1210,291,910 - 10,426,357 (-)EnsemblGRCr8
mRatBN7.2125,255,521 - 5,346,807 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl125,255,740 - 5,346,810 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx125,940,750 - 6,024,322 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0126,564,180 - 6,647,748 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0125,591,696 - 5,675,262 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0126,403,118 - 6,476,010 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl126,403,940 - 6,473,321 (+)Ensemblrn6Rnor6.0
Rnor_5.0128,485,545 - 8,576,783 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4125,695,579 - 5,706,396 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera127,034,312 - 7,117,929 (-)NCBICelera
Cytogenetic Map12p11NCBI
B3GLCT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381331,199,975 - 31,332,276 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1331,199,975 - 31,332,276 (+)Ensemblhg38GRCh38
GRCh371331,774,112 - 31,906,413 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361330,672,112 - 30,804,413 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1312,841,849 - 12,974,020 (+)NCBICelera
Cytogenetic Map13q12.3NCBI
HuRef1312,600,539 - 12,717,555 (+)NCBIHuRef
CHM1_11331,741,727 - 31,874,040 (+)NCBICHM1_1
T2T-CHM13v2.01330,422,990 - 30,555,445 (+)NCBIT2T-CHM13v2.0
B3glct
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395149,601,565 - 149,686,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5149,601,695 - 149,686,064 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385149,678,100 - 149,762,599 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5149,678,230 - 149,762,599 (+)Ensemblmm10GRCm38
MGSCv375150,480,832 - 150,565,174 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365149,946,636 - 150,030,978 (+)NCBIMGSCv36mm8
Celera5147,678,917 - 147,763,679 (+)NCBICelera
Cytogenetic Map5G3NCBI
cM Map589.18NCBI
B3glct
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543114,507,184 - 14,633,351 (-)Ensembl
ChiLan1.0NW_00495543114,507,184 - 14,621,376 (-)NCBIChiLan1.0ChiLan1.0
B3GLCT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21430,782,142 - 30,907,554 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11321,888,398 - 22,012,836 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01312,475,095 - 12,601,818 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11330,913,127 - 31,038,347 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1330,927,270 - 31,035,719 (+)EnsemblpanPan2panpan1.1
B3GLCT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,815,681 - 8,938,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,817,628 - 8,939,249 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha258,858,395 - 8,981,403 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0258,920,118 - 9,043,371 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl258,910,525 - 9,043,736 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1258,817,894 - 8,942,955 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0258,825,921 - 8,950,637 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,869,284 - 8,992,465 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
B3glct
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945169,960,358 - 170,042,161 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647225,942,662 - 26,006,288 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647225,909,994 - 25,991,800 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
B3GLCT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl117,792,368 - 7,907,049 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1117,792,160 - 7,907,052 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2117,763,470 - 7,875,165 (+)NCBISscrofa10.2Sscrofa10.2susScr3
B3GLCT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1310,058,041 - 10,178,996 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl310,059,196 - 10,179,037 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605734,188,163 - 34,309,750 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
B3glct
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247766,825,204 - 6,922,791 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247766,823,388 - 6,954,114 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
B3glct
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1164,095,352 - 4,178,909 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in B3glct
631 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12115486827Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1357337Gluco3Glucose level QTL 30.0004adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)12116966671Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
61334Gluco17Glucose level QTL 176.3adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)12116966671Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12111869600Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat

Markers in Region
RH135180  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2125,258,321 - 5,258,515 (-)MAPPERmRatBN7.2
Rnor_6.0126,473,016 - 6,473,209NCBIRnor6.0
Rnor_5.0128,573,789 - 8,573,982UniSTSRnor5.0
RGSC_v3.4125,667,595 - 5,667,788UniSTSRGSC3.4
Celera127,037,113 - 7,037,306UniSTS
Cytogenetic Map12p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 69 185 91 90 59 122 59 6 420 225 12 171 112 100 31 28 28

Sequence


Ensembl Acc Id: ENSRNOT00000083484   ⟹   ENSRNOP00000069223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1210,291,910 - 10,365,213 (-)Ensembl
mRatBN7.2 Ensembl125,257,150 - 5,328,831 (-)Ensembl
Rnor_6.0 Ensembl126,403,940 - 6,473,321 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110003   ⟹   ENSRNOP00000084499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1210,291,910 - 10,363,461 (-)Ensembl
mRatBN7.2 Ensembl125,257,150 - 5,324,259 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116254   ⟹   ENSRNOP00000092873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1210,291,910 - 10,360,566 (-)Ensembl
mRatBN7.2 Ensembl125,255,740 - 5,346,810 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000123458   ⟹   ENSRNOP00000109316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1210,291,910 - 10,426,357 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000159053   ⟹   ENSRNOP00000109731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1210,291,910 - 10,383,474 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000160913   ⟹   ENSRNOP00000099308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1210,291,910 - 10,348,099 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000168378   ⟹   ENSRNOP00000099917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1210,291,910 - 10,383,385 (-)Ensembl
RefSeq Acc Id: NM_001398955   ⟹   NP_001385884
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81210,291,910 - 10,383,190 (-)NCBI
mRatBN7.2125,255,521 - 5,346,807 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001385884 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069223.2
  ENSRNOP00000084499.2
  ENSRNOP00000092873.2
  ENSRNOP00000099308.1
  ENSRNOP00000099917.1
  ENSRNOP00000109316.1
  ENSRNOP00000109731
  ENSRNOP00000109731.1
Ensembl Acc Id: ENSRNOP00000069223   ⟸   ENSRNOT00000083484
Ensembl Acc Id: ENSRNOP00000084499   ⟸   ENSRNOT00000110003
Ensembl Acc Id: ENSRNOP00000092873   ⟸   ENSRNOT00000116254
RefSeq Acc Id: NP_001385884   ⟸   NM_001398955
- Peptide Label: precursor
- UniProtKB: A0A0G2JUT7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109731   ⟸   ENSRNOT00000159053
Ensembl Acc Id: ENSRNOP00000109316   ⟸   ENSRNOT00000123458
Ensembl Acc Id: ENSRNOP00000099917   ⟸   ENSRNOT00000168378
Ensembl Acc Id: ENSRNOP00000099308   ⟸   ENSRNOT00000160913
Protein Domains
Fringe-like glycosyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JUT7-F1-model_v2 AlphaFold A0A0G2JUT7 1-485 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1588723 AgrOrtholog
BioCyc Gene G2FUF-20213 BioCyc
Ensembl Genes ENSRNOG00000061346 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000083484.3 UniProtKB/TrEMBL
  ENSRNOT00000110003.2 UniProtKB/TrEMBL
  ENSRNOT00000116254.2 UniProtKB/TrEMBL
  ENSRNOT00000123458.1 UniProtKB/TrEMBL
  ENSRNOT00000159053 ENTREZGENE
  ENSRNOT00000159053.1 UniProtKB/TrEMBL
  ENSRNOT00000160913.1 UniProtKB/TrEMBL
  ENSRNOT00000168378.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.50 UniProtKB/TrEMBL
InterPro Fringe-like UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
NCBI Gene 689765 ENTREZGENE
PANTHER FRINGE-RELATED UniProtKB/TrEMBL
Pfam Fringe UniProtKB/TrEMBL
PhenoGen B3glct PhenoGen
RatGTEx ENSRNOG00000061346 RatGTEx
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt A0A0G2JUT7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GBW9_RAT UniProtKB/TrEMBL
  A0A8I6GKE1_RAT UniProtKB/TrEMBL
  A0ABK0L5E0_RAT UniProtKB/TrEMBL
  A0ABK0LB42_RAT UniProtKB/TrEMBL
  A0ABK0LW29_RAT UniProtKB/TrEMBL
  A0ABK0M5R8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-10 B3glct  beta 3-glucosyltransferase  B3galtl  beta 1,3-galactosyltransferase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-05 B3galtl  beta 1,3-galactosyltransferase-like  B3galtl-ps1  beta 1,3-galactosyltransferase-like, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-06-07 B3galtl-ps1  beta 1,3-galactosyltransferase-like, pseudogene 1  B3galtl  beta 1,3-galactosyltransferase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 B3galtl  beta 1,3-galactosyltransferase-like  LOC689765  similar to beta 3-glycosyltransferase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC689765  similar to beta 3-glycosyltransferase-like      Symbol and Name status set to provisional 70820 PROVISIONAL