Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial transcription; positive regulation of DNA-templated transcription; and translation. Predicted to be located in mitochondrial matrix. Predicted to be part of mitochondrial large ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 45. Orthologous to human MRPL12 (mitochondrial ribosomal protein L12); INTERACTS WITH 17beta-estradiol; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene.
[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MRPL12 mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to MRPL12 promoter]
[Aflatoxin B1 co-treated with aflatoxin B2 co-treated with aflatoxin G1 co-treated with aflatoxin G2] results in decreased expression of MRPL12 mRNA and [Plant Extracts co-treated with Aflatoxin B1 co-treated with aflatoxin B2 co-treated with aflatoxin G1 co-treated with aflatoxin G2] results in decreased expression of MRPL12 mRNA
[Aflatoxin B1 co-treated with aflatoxin B2 co-treated with aflatoxin G1 co-treated with aflatoxin G2] results in decreased expression of MRPL12 mRNA and [Plant Extracts co-treated with Aflatoxin B1 co-treated with aflatoxin B2 co-treated with aflatoxin G1 co-treated with aflatoxin G2] results in decreased expression of MRPL12 mRNA
[Aflatoxin B1 co-treated with aflatoxin B2 co-treated with aflatoxin G1 co-treated with aflatoxin G2] results in decreased expression of MRPL12 mRNA and [Plant Extracts co-treated with Aflatoxin B1 co-treated with aflatoxin B2 co-treated with aflatoxin G1 co-treated with aflatoxin G2] results in decreased expression of MRPL12 mRNA
[Aflatoxin B1 co-treated with aflatoxin B2 co-treated with aflatoxin G1 co-treated with aflatoxin G2] results in decreased expression of MRPL12 mRNA and [Plant Extracts co-treated with Aflatoxin B1 co-treated with aflatoxin B2 co-treated with aflatoxin G1 co-treated with aflatoxin G2] results in decreased expression of MRPL12 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA and [Plant Extracts co-treated with enniatins] results in decreased expression of MRPL12 mRNA
[LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of MRPL12 protein
Identification of mammalian mitochondrial ribosomal proteins (MRPs) by N-terminal sequencing of purified bovine MRPs and comparison to data bank sequences: the large subribosomal particle.