Elovl1 (ELOVL fatty acid elongase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Elovl1 (ELOVL fatty acid elongase 1) Rattus norvegicus
Analyze
Symbol: Elovl1
Name: ELOVL fatty acid elongase 1
RGD ID: 1587151
Description: Predicted to enable fatty acid elongase activity. Predicted to be involved in ceramide biosynthetic process; establishment of skin barrier; and fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ELOVL1 (ELOVL fatty acid elongase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1; elongation of very long chain fatty acids protein 1; hypothetical protein LOC679532; LOC679532; similar to Elongation of very long chain fatty acids protein 1; very long chain fatty acid elongase 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85137,246,781 - 137,251,351 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5137,246,849 - 137,251,352 (+)EnsemblGRCr8
mRatBN7.25131,961,478 - 131,965,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,961,322 - 131,965,958 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5134,670,003 - 134,673,190 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05136,424,640 - 136,427,827 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05136,447,038 - 136,450,225 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05137,255,868 - 137,260,486 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5137,255,908 - 137,260,483 (+)Ensemblrn6Rnor6.0
Rnor_5.05141,046,751 - 141,049,947 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45138,909,438 - 138,912,186 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5130,508,244 - 130,511,440 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-bromohexadecanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
alpha-phellandrene  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
Bufotalin  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlormequat chloride  (EXP)
chloroprene  (ISO)
chlorpyrifos  (ISO)
copper(II) chloride  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
fonofos  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
GW 4064  (ISO)
GW 7647  (ISO)
hydrogen cyanide  (ISO)
indole-3-methanol  (EXP)
isoniazide  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
obeticholic acid  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
potassium cyanide  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
tamoxifen  (ISO)
terbufos  (ISO)
tetraphene  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thiram  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10970790   PMID:12477932   PMID:19946888   PMID:20166112   PMID:20253178   PMID:20937905   PMID:23689133  


Genomics

Comparative Map Data
Elovl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85137,246,781 - 137,251,351 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5137,246,849 - 137,251,352 (+)EnsemblGRCr8
mRatBN7.25131,961,478 - 131,965,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,961,322 - 131,965,958 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5134,670,003 - 134,673,190 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05136,424,640 - 136,427,827 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05136,447,038 - 136,450,225 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05137,255,868 - 137,260,486 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5137,255,908 - 137,260,483 (+)Ensemblrn6Rnor6.0
Rnor_5.05141,046,751 - 141,049,947 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45138,909,438 - 138,912,186 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5130,508,244 - 130,511,440 (+)NCBICelera
Cytogenetic Map5q36NCBI
ELOVL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38143,363,401 - 43,368,011 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl143,363,396 - 43,368,075 (-)Ensemblhg38GRCh38
GRCh37143,829,072 - 43,833,682 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36143,601,659 - 43,606,286 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34143,498,165 - 43,502,792NCBI
Celera142,111,226 - 42,115,853 (-)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef141,948,810 - 41,953,487 (-)NCBIHuRef
CHM1_1143,945,527 - 43,950,204 (-)NCBICHM1_1
T2T-CHM13v2.0143,233,949 - 43,238,559 (-)NCBIT2T-CHM13v2.0
Elovl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394118,285,321 - 118,290,150 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4118,285,290 - 118,290,150 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384118,426,874 - 118,432,953 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4118,428,093 - 118,432,953 (+)Ensemblmm10GRCm38
MGSCv374118,100,698 - 118,105,521 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364117,926,025 - 117,930,848 (+)NCBIMGSCv36mm8
Celera4117,153,631 - 117,158,454 (+)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map454.61NCBI
Elovl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555372,945,509 - 2,950,146 (-)Ensembl
ChiLan1.0NW_0049555372,945,509 - 2,950,146 (-)NCBIChiLan1.0ChiLan1.0
ELOVL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21183,424,960 - 183,446,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11182,566,350 - 182,588,012 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0142,664,818 - 42,686,475 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1144,044,693 - 44,064,111 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl144,044,693 - 44,048,769 (-)EnsemblpanPan2panpan1.1
ELOVL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11516,798,305 - 16,803,071 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1516,798,370 - 16,802,899 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1516,925,313 - 16,930,087 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01516,965,026 - 16,969,802 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1516,965,100 - 16,969,969 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11516,757,503 - 16,762,275 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01516,826,506 - 16,831,275 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01516,900,074 - 16,904,850 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Elovl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505858,940,387 - 58,945,152 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647424,764,718 - 24,769,947 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647424,765,173 - 24,769,903 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOVL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6167,881,352 - 167,886,124 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16167,881,357 - 167,886,125 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26155,333,073 - 155,340,903 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELOVL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12089,444,146 - 89,448,802 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603327,472,819 - 27,477,500 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elovl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248922,675,421 - 2,684,622 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248922,679,872 - 2,684,499 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Elovl1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1138,595,544 - 38,600,131 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Elovl1
13 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:65
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000037160
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5130678987145274255Rat
7365049Bp359Blood pressure QTL 359arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133308734140009902Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
D5Wox40  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85137,251,262 - 137,251,433 (+)Marker Load Pipeline
mRatBN7.25131,965,869 - 131,966,040 (+)MAPPERmRatBN7.2
Rnor_6.05137,260,395 - 137,260,565NCBIRnor6.0
Rnor_5.05141,049,859 - 141,050,029UniSTSRnor5.0
Celera5130,511,352 - 130,511,522UniSTS
Cytogenetic Map5q36UniSTS
BB151133  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25131,965,773 - 131,965,865 (+)MAPPERmRatBN7.2
Rnor_6.05137,260,299 - 137,260,390NCBIRnor6.0
Rnor_5.05141,049,763 - 141,049,854UniSTSRnor5.0
Celera5130,511,256 - 130,511,347UniSTS
Cytogenetic Map5q36UniSTS
AA963388  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25131,965,784 - 131,965,938 (+)MAPPERmRatBN7.2
Rnor_6.05137,260,310 - 137,260,463NCBIRnor6.0
Rnor_5.05141,049,774 - 141,049,927UniSTSRnor5.0
Celera5130,511,267 - 130,511,420UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000037160   ⟹   ENSRNOP00000033374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5137,246,849 - 137,251,352 (+)Ensembl
mRatBN7.2 Ensembl5131,961,446 - 131,965,956 (+)Ensembl
Rnor_6.0 Ensembl5137,257,287 - 137,260,483 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088022   ⟹   ENSRNOP00000074677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5137,246,914 - 137,251,349 (+)Ensembl
mRatBN7.2 Ensembl5131,961,322 - 131,965,937 (+)Ensembl
Rnor_6.0 Ensembl5137,255,924 - 137,259,796 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092755   ⟹   ENSRNOP00000075935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5137,246,849 - 137,251,349 (+)Ensembl
mRatBN7.2 Ensembl5131,963,915 - 131,965,958 (+)Ensembl
Rnor_6.0 Ensembl5137,255,925 - 137,259,949 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5137,255,908 - 137,258,982 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5137,258,844 - 137,259,804 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5137,258,424 - 137,259,626 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093001   ⟹   ENSRNOP00000075969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5137,248,670 - 137,251,352 (+)Ensembl
mRatBN7.2 Ensembl5131,963,037 - 131,965,956 (+)Ensembl
Rnor_6.0 Ensembl5137,257,637 - 137,259,546 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5137,255,922 - 137,259,177 (+)Ensembl
RefSeq Acc Id: NM_001044275   ⟹   NP_001037740
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85137,248,155 - 137,251,351 (+)NCBI
mRatBN7.25131,962,762 - 131,965,958 (+)NCBI
Rnor_6.05137,257,287 - 137,260,483 (+)NCBI
Rnor_5.05141,046,751 - 141,049,947 (+)NCBI
RGSC_v3.45138,909,438 - 138,912,186 (+)RGD
Celera5130,508,244 - 130,511,440 (+)RGD
Sequence:
RefSeq Acc Id: XM_017593616   ⟹   XP_017449105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85137,246,781 - 137,251,351 (+)NCBI
mRatBN7.25131,961,478 - 131,965,961 (+)NCBI
Rnor_6.05137,255,868 - 137,260,486 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593617   ⟹   XP_017449106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85137,246,968 - 137,251,351 (+)NCBI
mRatBN7.25131,961,573 - 131,965,959 (+)NCBI
Rnor_6.05137,256,253 - 137,260,486 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593618   ⟹   XP_017449107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85137,246,968 - 137,251,351 (+)NCBI
mRatBN7.25131,961,573 - 131,965,959 (+)NCBI
Rnor_6.05137,256,253 - 137,260,486 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001037740   ⟸   NM_001044275
- UniProtKB: Q5U2Z8 (UniProtKB/TrEMBL),   A0A0G2K8N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449105   ⟸   XM_017593616
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017449107   ⟸   XM_017593618
- Peptide Label: isoform X1
- UniProtKB: Q5U2Z8 (UniProtKB/TrEMBL),   A0A0G2K8N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449106   ⟸   XM_017593617
- Peptide Label: isoform X1
- UniProtKB: Q5U2Z8 (UniProtKB/TrEMBL),   A0A0G2K8N7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075935   ⟸   ENSRNOT00000092755
Ensembl Acc Id: ENSRNOP00000075969   ⟸   ENSRNOT00000093001
Ensembl Acc Id: ENSRNOP00000074677   ⟸   ENSRNOT00000088022
Ensembl Acc Id: ENSRNOP00000033374   ⟸   ENSRNOT00000037160

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2Z8-F1-model_v2 AlphaFold Q5U2Z8 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693965
Promoter ID:EPDNEW_R4488
Type:initiation region
Name:Elovl1_1
Description:ELOVL fatty acid elongase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4489  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05137,255,911 - 137,255,971EPDNEW
RGD ID:13693969
Promoter ID:EPDNEW_R4489
Type:initiation region
Name:Elovl1_2
Description:ELOVL fatty acid elongase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4488  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05137,257,590 - 137,257,650EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1587151 AgrOrtholog
BioCyc Gene G2FUF-40156 BioCyc
Ensembl Genes ENSRNOG00000028448 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037160 ENTREZGENE
  ENSRNOT00000037160.5 UniProtKB/TrEMBL
  ENSRNOT00000088022.4 UniProtKB/TrEMBL
  ENSRNOT00000092755.3 UniProtKB/TrEMBL
  ENSRNOT00000093001.3 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109632 IMAGE-MGC_LOAD
InterPro ELO_CS UniProtKB/TrEMBL
  ELOVL1 UniProtKB/TrEMBL
  GNS1_SUR4 UniProtKB/TrEMBL
KEGG Report rno:679532 UniProtKB/TrEMBL
MGC_CLONE MGC:93791 IMAGE-MGC_LOAD
NCBI Gene 679532 ENTREZGENE
PANTHER ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1 UniProtKB/TrEMBL
  GNS1_SUR4 UniProtKB/TrEMBL
Pfam ELO UniProtKB/TrEMBL
PhenoGen Elovl1 PhenoGen
PROSITE ELO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028448 RatGTEx
UniProt A0A0G2K8N7 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GWL0_RAT UniProtKB/TrEMBL
  A0A1B0GWP1_RAT UniProtKB/TrEMBL
  F7F9G6_RAT UniProtKB/TrEMBL
  Q5U2Z8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Elovl1  ELOVL fatty acid elongase 1  Elovl1  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-21 Elovl1  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1  LOC679532  similar to Elongation of very long chain fatty acids protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC679532  similar to Elongation of very long chain fatty acids protein 1  LOC684910  similar to Elongation of very long chain fatty acids protein 1  Data merged from RGD:1584445 1643240 APPROVED
2006-11-19 LOC679532  similar to Elongation of very long chain fatty acids protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684910  similar to Elongation of very long chain fatty acids protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL