Elovl1 (ELOVL fatty acid elongase 1) - Rat Genome Database

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Gene: Elovl1 (ELOVL fatty acid elongase 1) Rattus norvegicus
Analyze
Symbol: Elovl1
Name: ELOVL fatty acid elongase 1
RGD ID: 1587151
Description: Predicted to enable fatty acid elongase activity. Predicted to be involved in ceramide biosynthetic process; establishment of skin barrier; and fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ELOVL1 (ELOVL fatty acid elongase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1; elongation of very long chain fatty acids protein 1; hypothetical protein LOC679532; LOC679532; similar to Elongation of very long chain fatty acids protein 1; very long chain fatty acid elongase 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85137,246,781 - 137,251,351 (+)NCBIGRCr8
mRatBN7.25131,961,478 - 131,965,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,961,322 - 131,965,958 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5134,670,003 - 134,673,190 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05136,424,640 - 136,427,827 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05136,447,038 - 136,450,225 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05137,255,868 - 137,260,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5137,255,908 - 137,260,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05141,046,751 - 141,049,947 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45138,909,438 - 138,912,186 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5130,508,244 - 130,511,440 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Elovl1RatCharcot-Marie-Tooth disease dominant intermediate C  ISOELOVL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate CClinVarPMID:28492532
Elovl1RatICHTHYOTIC KERATODERMA, SPASTICITY, HYPOMYELINATION, AND DYSMORPHIC FACIAL FEATURES  ISOELOVL1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Elovl1Ratoptic atrophy  ISOELOVL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Optic atrophyClinVarPMID:25741868 and PMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Elovl1RatICHTHYOTIC KERATODERMA, SPASTICITY, HYPOMYELINATION, AND DYSMORPHIC FACIAL FEATURES  ISOELOVL1 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Elovl1Rat(-)-alpha-phellandrene decreases expressionISOELOVL1 (Homo sapiens)6480464alpha phellandrene results in decreased expression of ELOVL1 mRNACTDPMID:25075043
Elovl1Rat(-)-epigallocatechin 3-gallate multiple interactionsISOELOVL1 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ELOVL1 mRNACTDPMID:22079256
Elovl1Rat(1->4)-beta-D-glucan multiple interactionsISOElovl1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ELOVL1 mRNACTDPMID:36331819
Elovl1Rat1,2-dimethylhydrazine multiple interactionsISOElovl1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOVL1 mRNACTDPMID:22206623
Elovl1Rat17beta-estradiol affects expressionISOELOVL1 (Homo sapiens)6480464Estradiol affects the expression of ELOVL1 mRNACTDPMID:22574217
Elovl1Rat17beta-estradiol increases expressionISOElovl1 (Mus musculus)6480464Estradiol results in increased expression of ELOVL1 mRNACTDPMID:39298647
Elovl1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOElovl1 (Mus musculus)6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ELOVL1 promoter]CTDPMID:19654925
Elovl1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of ELOVL1 mRNACTDPMID:34747641
Elovl1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOElovl1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ELOVL1 mRNACTDPMID:21570461
Elovl1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOELOVL1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of ELOVL1 mRNACTDPMID:20106945 and PMID:21632981
Elovl1Rat2-bromohexadecanoic acid multiple interactionsISOELOVL1 (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ELOVL1 protein]CTDPMID:38195004
Elovl1Rat2-hydroxypropanoic acid decreases expressionISOELOVL1 (Homo sapiens)6480464Lactic Acid results in decreased expression of ELOVL1 mRNACTDPMID:30851411
Elovl1Rat4-hydroxyphenyl retinamide decreases expressionISOElovl1 (Mus musculus)6480464Fenretinide results in decreased expression of ELOVL1 mRNACTDPMID:28973697
Elovl1Rat6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime increases expressionISOELOVL1 (Homo sapiens)64804646-(4-chlorophenyl)imidazo(2 more ...CTDPMID:30611723
Elovl1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of ELOVL1 mRNACTDPMID:24780913
Elovl1Ratacrolein multiple interactionsISOELOVL1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of ELOVL1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of ELOVL1 mRNACTDPMID:32699268
Elovl1Ratacrylamide increases expressionISOELOVL1 (Homo sapiens)6480464Acrylamide results in increased expression of ELOVL1 mRNACTDPMID:32763439
Elovl1Ratalpha-phellandrene decreases expressionISOELOVL1 (Homo sapiens)6480464alpha phellandrene results in decreased expression of ELOVL1 mRNACTDPMID:25075043
Elovl1Ratalpha-pinene multiple interactionsISOELOVL1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of ELOVL1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of ELOVL1 mRNACTDPMID:32699268
Elovl1Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of ELOVL1 mRNACTDPMID:38685447

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Biological Process
1 to 20 of 28 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Elovl1Ratceramide biosynthetic process involved_inISOElovl1 (Mus musculus)1624291 PMID:23689133RGDPMID:23689133
Elovl1Ratestablishment of skin barrier involved_inISOElovl1 (Mus musculus)1624291 PMID:23689133RGDPMID:23689133
Elovl1Ratfatty acid biosynthetic process involved_inIEAUniProtKB-KW:KW-02751600115GO_REF:0000043UniProtGO_REF:0000043
Elovl1Ratfatty acid biosynthetic process involved_inIEAUniPathway:UPA000941600115GO_REF:0000041UniProtGO_REF:0000041
Elovl1Ratfatty acid elongation, monounsaturated fatty acid involved_inISOELOVL1 (Homo sapiens)1624291 PMID:20166112RGDPMID:20166112
Elovl1Ratfatty acid elongation, monounsaturated fatty acid involved_inIEAUniRule:UR0002549341600115GO_REF:0000104UniProtGO_REF:0000104
Elovl1Ratfatty acid elongation, monounsaturated fatty acid involved_inIEAUniProtKB:Q9BW60 and ensembl:ENSP000003615361600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl1Ratfatty acid elongation, monounsaturated fatty acid involved_inIBAMGI:1195976 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl1Ratfatty acid elongation, polyunsaturated fatty acid involved_inIBAMGI:1858960 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl1Ratfatty acid elongation, saturated fatty acid involved_inISOELOVL1 (Homo sapiens)1624291 PMID:20166112 and PMID:20937905RGDPMID:20166112 and PMID:20937905
Elovl1Ratfatty acid elongation, saturated fatty acid involved_inIEAUniProtKB:Q9BW60 and ensembl:ENSP000003615361600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl1Ratfatty acid elongation, saturated fatty acid involved_inIEAUniRule:UR0002549341600115GO_REF:0000104UniProtGO_REF:0000104
Elovl1Ratfatty acid elongation, saturated fatty acid involved_inIEAInterPro:IPR0336811600115GO_REF:0000002InterProGO_REF:0000002
Elovl1Ratfatty acid elongation, saturated fatty acid involved_inIBAFB:FBgn0260960 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl1Ratfatty acid metabolic process involved_inIEAUniProtKB-KW:KW-02761600115GO_REF:0000043UniProtGO_REF:0000043
Elovl1Ratlipid biosynthetic process involved_inIEAARBA:ARBA000272361600115GO_REF:0000117UniProtGO_REF:0000117
Elovl1Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Elovl1Ratlong-chain fatty-acyl-CoA biosynthetic process involved_inIEAUniRule:UR0002549341600115GO_REF:0000104UniProtGO_REF:0000104
Elovl1Ratsphingolipid biosynthetic process involved_inISOELOVL1 (Homo sapiens)1624291 PMID:20937905RGDPMID:20937905
Elovl1Ratsphingolipid biosynthetic process involved_inISOElovl1 (Mus musculus)1624291 PMID:20253178RGDPMID:20253178
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Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Elovl1Ratendoplasmic reticulum located_inISOELOVL1 (Homo sapiens)1624291 PMID:20937905RGDPMID:20937905
Elovl1Ratendoplasmic reticulum located_inIEAUniProtKB:Q9BW60 and ensembl:ENSP000003615361600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl1Ratendoplasmic reticulum located_inIEAInterPro:IPR0336811600115GO_REF:0000002InterProGO_REF:0000002
Elovl1Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Elovl1Ratendoplasmic reticulum located_inISOELOVL1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Elovl1Ratendoplasmic reticulum membrane is_active_inIBAMGI:2156528 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl1Ratendoplasmic reticulum membrane located_inIEAUniRule:UR0002549341600115GO_REF:0000104UniProtGO_REF:0000104
Elovl1Ratendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Elovl1Ratmembrane located_inIEAInterPro:IPR0020761600115GO_REF:0000002InterProGO_REF:0000002
Elovl1Ratmembrane located_inIEAUniRule:UR0002549341600115GO_REF:0000104UniProtGO_REF:0000104
Elovl1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Elovl1Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
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Molecular Function
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Elovl1Ratfatty acid elongase activity enablesISOELOVL1 (Homo sapiens)1624291 PMID:10970790 and PMID:20166112RGDPMID:10970790 and PMID:20166112
Elovl1Ratfatty acid elongase activity enablesIEARHEA:327271600115GO_REF:0000116RHEAGO_REF:0000116
Elovl1Ratfatty acid elongase activity enablesIEAInterPro:IPR0020761600115GO_REF:0000002InterProGO_REF:0000002
Elovl1Ratfatty acid elongase activity enablesIEAUniProtKB:Q9BW60 and ensembl:ENSP000003615361600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl1Ratfatty acid elongase activity enablesIEAEC:2.3.1.1991600115GO_REF:0000003UniProtGO_REF:0000003
Elovl1Ratfatty acid elongase activity enablesIEAInterPro:IPR002076 and InterPro:IPR0336811600115GO_REF:0000002InterProGO_REF:0000002
Elovl1Ratfatty acid elongase activity enablesIBAFB:FBgn0034382 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl1Ratfatty acid elongase activity enablesIEAUniRule:UR0002549341600115GO_REF:0000104UniProtGO_REF:0000104
Elovl1Ratprotein binding enablesISOELOVL1 (Homo sapiens)1624291UniProtKB:Q53GQ0 more ...RGDPMID:20937905 and PMID:38422897
Elovl1Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:10970790   PMID:12477932   PMID:19946888   PMID:20166112   PMID:20253178   PMID:20937905   PMID:23689133  



Elovl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85137,246,781 - 137,251,351 (+)NCBIGRCr8
mRatBN7.25131,961,478 - 131,965,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,961,322 - 131,965,958 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5134,670,003 - 134,673,190 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05136,424,640 - 136,427,827 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05136,447,038 - 136,450,225 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05137,255,868 - 137,260,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5137,255,908 - 137,260,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05141,046,751 - 141,049,947 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45138,909,438 - 138,912,186 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5130,508,244 - 130,511,440 (+)NCBICelera
Cytogenetic Map5q36NCBI
ELOVL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38143,363,401 - 43,368,011 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl143,363,398 - 43,368,074 (-)EnsemblGRCh38hg38GRCh38
GRCh37143,829,072 - 43,833,682 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36143,601,659 - 43,606,286 (-)NCBINCBI36Build 36hg18NCBI36
Build 34143,498,165 - 43,502,792NCBI
Celera142,111,226 - 42,115,853 (-)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef141,948,810 - 41,953,487 (-)NCBIHuRef
CHM1_1143,945,527 - 43,950,204 (-)NCBICHM1_1
T2T-CHM13v2.0143,233,949 - 43,238,559 (-)NCBIT2T-CHM13v2.0
Elovl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394118,285,321 - 118,290,150 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4118,285,290 - 118,290,150 (+)EnsemblGRCm39 Ensembl
GRCm384118,426,874 - 118,432,953 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4118,428,093 - 118,432,953 (+)EnsemblGRCm38mm10GRCm38
MGSCv374118,100,698 - 118,105,521 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364117,926,025 - 117,930,848 (+)NCBIMGSCv36mm8
Celera4117,153,631 - 117,158,454 (+)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map454.61NCBI
Elovl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555372,945,509 - 2,950,146 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555372,945,509 - 2,950,146 (-)NCBIChiLan1.0ChiLan1.0
ELOVL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21183,424,960 - 183,446,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11182,566,350 - 182,588,012 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0142,664,818 - 42,686,475 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1144,044,693 - 44,064,111 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl144,044,693 - 44,048,769 (-)Ensemblpanpan1.1panPan2
ELOVL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11516,798,305 - 16,803,071 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1516,798,370 - 16,802,899 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1516,925,313 - 16,930,087 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01516,965,026 - 16,969,802 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1516,965,100 - 16,969,969 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11516,757,503 - 16,762,275 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01516,826,506 - 16,831,275 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01516,900,074 - 16,904,850 (+)NCBIUU_Cfam_GSD_1.0
Elovl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505858,940,387 - 58,945,152 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647424,764,718 - 24,769,947 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647424,765,173 - 24,769,903 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOVL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6167,881,352 - 167,886,124 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16167,881,357 - 167,886,125 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26155,333,073 - 155,340,903 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELOVL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12089,444,146 - 89,448,802 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603327,472,819 - 27,477,500 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elovl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248922,675,421 - 2,684,622 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248922,679,872 - 2,684,499 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Elovl1
13 total Variants

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:65
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000037160
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat

1 to 10 of 51 rows
D5Wox40  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85137,251,262 - 137,251,433 (+)Marker Load Pipeline
mRatBN7.25131,965,869 - 131,966,040 (+)MAPPERmRatBN7.2
Rnor_6.05137,260,395 - 137,260,565NCBIRnor6.0
Rnor_5.05141,049,859 - 141,050,029UniSTSRnor5.0
Celera5130,511,352 - 130,511,522UniSTS
Cytogenetic Map5q36UniSTS
BB151133  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25131,965,773 - 131,965,865 (+)MAPPERmRatBN7.2
Rnor_6.05137,260,299 - 137,260,390NCBIRnor6.0
Rnor_5.05141,049,763 - 141,049,854UniSTSRnor5.0
Celera5130,511,256 - 130,511,347UniSTS
Cytogenetic Map5q36UniSTS
AA963388  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25131,965,784 - 131,965,938 (+)MAPPERmRatBN7.2
Rnor_6.05137,260,310 - 137,260,463NCBIRnor6.0
Rnor_5.05141,049,774 - 141,049,927UniSTSRnor5.0
Celera5130,511,267 - 130,511,420UniSTS
Cytogenetic Map5q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000037160   ⟹   ENSRNOP00000033374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5131,961,446 - 131,965,956 (+)Ensembl
Rnor_6.0 Ensembl5137,257,287 - 137,260,483 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088022   ⟹   ENSRNOP00000074677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5131,961,322 - 131,965,937 (+)Ensembl
Rnor_6.0 Ensembl5137,255,924 - 137,259,796 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092755   ⟹   ENSRNOP00000075935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5131,963,915 - 131,965,958 (+)Ensembl
Rnor_6.0 Ensembl5137,255,925 - 137,259,949 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5137,255,908 - 137,258,982 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5137,258,844 - 137,259,804 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5137,258,424 - 137,259,626 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093001   ⟹   ENSRNOP00000075969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5131,963,037 - 131,965,956 (+)Ensembl
Rnor_6.0 Ensembl5137,257,637 - 137,259,546 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5137,255,922 - 137,259,177 (+)Ensembl
RefSeq Acc Id: NM_001044275   ⟹   NP_001037740
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85137,248,155 - 137,251,351 (+)NCBI
mRatBN7.25131,962,762 - 131,965,958 (+)NCBI
Rnor_6.05137,257,287 - 137,260,483 (+)NCBI
Rnor_5.05141,046,751 - 141,049,947 (+)NCBI
RGSC_v3.45138,909,438 - 138,912,186 (+)RGD
Celera5130,508,244 - 130,511,440 (+)RGD
Sequence:
RefSeq Acc Id: XM_017593616   ⟹   XP_017449105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85137,246,781 - 137,251,351 (+)NCBI
mRatBN7.25131,961,478 - 131,965,961 (+)NCBI
Rnor_6.05137,255,868 - 137,260,486 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593617   ⟹   XP_017449106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85137,246,968 - 137,251,351 (+)NCBI
mRatBN7.25131,961,573 - 131,965,959 (+)NCBI
Rnor_6.05137,256,253 - 137,260,486 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593618   ⟹   XP_017449107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85137,246,968 - 137,251,351 (+)NCBI
mRatBN7.25131,961,573 - 131,965,959 (+)NCBI
Rnor_6.05137,256,253 - 137,260,486 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001037740   ⟸   NM_001044275
- UniProtKB: Q5U2Z8 (UniProtKB/TrEMBL),   A0A0G2K8N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449105   ⟸   XM_017593616
- Peptide Label: isoform X1
- UniProtKB: Q5U2Z8 (UniProtKB/TrEMBL),   A0A0G2K8N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449107   ⟸   XM_017593618
- Peptide Label: isoform X1
- UniProtKB: Q5U2Z8 (UniProtKB/TrEMBL),   A0A0G2K8N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449106   ⟸   XM_017593617
- Peptide Label: isoform X1
- UniProtKB: Q5U2Z8 (UniProtKB/TrEMBL),   A0A0G2K8N7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075935   ⟸   ENSRNOT00000092755

Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2Z8-F1-model_v2 AlphaFold Q5U2Z8 1-279 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693965
Promoter ID:EPDNEW_R4488
Type:initiation region
Name:Elovl1_1
Description:ELOVL fatty acid elongase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4489  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05137,255,911 - 137,255,971EPDNEW
RGD ID:13693969
Promoter ID:EPDNEW_R4489
Type:initiation region
Name:Elovl1_2
Description:ELOVL fatty acid elongase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4488  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05137,257,590 - 137,257,650EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-40156 BioCyc
Ensembl Genes ENSRNOG00000028448 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037160 ENTREZGENE
  ENSRNOT00000037160.4 UniProtKB/TrEMBL
  ENSRNOT00000088022.3 UniProtKB/TrEMBL
  ENSRNOT00000092755.2 UniProtKB/TrEMBL
  ENSRNOT00000093001.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109632 IMAGE-MGC_LOAD
InterPro ELO_CS UniProtKB/TrEMBL
  ELOVL1 UniProtKB/TrEMBL
  GNS1_SUR4 UniProtKB/TrEMBL
KEGG Report rno:679532 UniProtKB/TrEMBL
MGC_CLONE MGC:93791 IMAGE-MGC_LOAD
NCBI Gene 679532 ENTREZGENE
PANTHER ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1 UniProtKB/TrEMBL
  GNS1_SUR4 UniProtKB/TrEMBL
Pfam ELO UniProtKB/TrEMBL
PhenoGen Elovl1 PhenoGen
PROSITE ELO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028448 RatGTEx
UniProt A0A0G2K8N7 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GWL0_RAT UniProtKB/TrEMBL
  A0A1B0GWP1_RAT UniProtKB/TrEMBL
  F7F9G6_RAT UniProtKB/TrEMBL
  Q5U2Z8 ENTREZGENE, UniProtKB/TrEMBL
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Elovl1  ELOVL fatty acid elongase 1  Elovl1  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-21 Elovl1  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1  LOC679532  similar to Elongation of very long chain fatty acids protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC679532  similar to Elongation of very long chain fatty acids protein 1  LOC684910  similar to Elongation of very long chain fatty acids protein 1  Data merged from RGD:1584445 1643240 APPROVED
2006-11-19 LOC679532  similar to Elongation of very long chain fatty acids protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684910  similar to Elongation of very long chain fatty acids protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL