Rgs20 (regulator of G-protein signaling 20)

Gene: Rgs20 (regulator of G-protein signaling 20) Rattus norvegicus

Analyze

Symbol:

Rgs20

Name:

regulator of G-protein signaling 20

RGD ID:

1586146

Description:

Involved in response to amphetamine. Predicted to be located in trans-Golgi network. Orthologous to human RGS20 (regulator of G protein signaling 20); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC362477; similar to Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1)

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RGS20 (regulator of G protein signaling 20)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Rgs20 (regulator of G-protein signaling 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rgs20 (regulator of G protein signaling 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RGS20 (regulator of G protein signaling 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RGS20 (regulator of G protein signaling 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rgs20 (regulator of G protein signaling 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RGS20 (regulator of G protein signaling 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RGS20 (regulator of G protein signaling 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rgs20 (regulator of G protein signaling 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CPXM2 (carboxypeptidase X, M14 family member 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RGS20 (regulator of G protein signaling 20)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rgs20 (regulator of G-protein signaling 20)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rgs20 (regulator of G protein signaling 20)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rgs-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Dhit	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rgs-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rgs20	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	19,282,249 - 19,412,122 (+)	NCBI		GRCr8
mRatBN7.2	5	14,484,436 - 14,614,317 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	14,534,775 - 14,614,084 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	16,676,816 - 17,279,107 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	18,284,572 - 18,882,373 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	18,011,498 - 18,613,725 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	14,367,498 - 14,494,048 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	14,415,606 - 14,494,756 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	19,197,565 - 19,275,548 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	14,737,677 - 14,816,606 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	13,906,964 - 13,985,237 (+)	NCBI		Celera
Cytogenetic Map	5	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-hydroxypropanoic acid (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

5-aza-2'-deoxycytidine (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

butan-1-ol (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

cisplatin (ISO)

cocaine (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

diethylstilbestrol (EXP)

diquat (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

gallic acid (ISO)

isobutanol (ISO)

lipopolysaccharide (ISO)

methyl methanesulfonate (ISO)

methylphenidate (ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

ochratoxin A (EXP)

paracetamol (EXP)

paraquat (ISO)

phenylmercury acetate (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

topotecan (ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of signal transduction (IEA)

response to amphetamine (IEP)

Cellular Component

cytoplasm (ISO)

trans-Golgi network (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration.	Sun H, etal., Neuroscience. 2015 Oct 29;307:253-61. doi: 10.1016/j.neuroscience.2015.08.053. Epub 2015 Aug 28.

Additional References at PubMed

PMID:10791963	PMID:12477932	PMID:22871113	PMID:25402859

Genomics

Comparative Map Data

Rgs20
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	19,282,249 - 19,412,122 (+)	NCBI		GRCr8
mRatBN7.2	5	14,484,436 - 14,614,317 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	14,534,775 - 14,614,084 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	16,676,816 - 17,279,107 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	18,284,572 - 18,882,373 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	18,011,498 - 18,613,725 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	14,367,498 - 14,494,048 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	14,415,606 - 14,494,756 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	19,197,565 - 19,275,548 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	14,737,677 - 14,816,606 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	13,906,964 - 13,985,237 (+)	NCBI		Celera
Cytogenetic Map	5	q12	NCBI

RGS20
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	53,851,795 - 53,959,303 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	53,851,795 - 53,959,303 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	54,764,355 - 54,871,864 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	54,926,921 - 55,034,416 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	54,926,920 - 55,034,416	NCBI
Celera	8	50,754,534 - 50,862,294 (+)	NCBI		Celera
Cytogenetic Map	8	q11.23	NCBI
HuRef	8	50,231,893 - 50,339,515 (+)	NCBI		HuRef
CHM1_1	8	54,816,161 - 54,923,378 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	54,229,188 - 54,336,699 (+)	NCBI		T2T-CHM13v2.0

Rgs20
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	4,976,342 - 5,140,528 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	4,979,799 - 5,140,508 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	4,909,573 - 5,070,299 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	4,909,576 - 5,070,285 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	4,899,657 - 5,060,366 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	4,900,326 - 5,009,967 (-)	NCBI		MGSCv36	mm8
Celera	1	4,920,984 - 5,081,194 (-)	NCBI		Celera
Cytogenetic Map	1	A1	NCBI
cM Map	1	1.8	NCBI

Rgs20
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955454	13,271,409 - 13,305,730 (+)	NCBI	ChiLan1.0	ChiLan1.0

RGS20
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	69,516,347 - 69,597,914 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	45,241,161 - 45,322,695 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	50,277,765 - 50,386,289 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	47,655,584 - 47,763,411 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	47,655,584 - 47,763,411 (+)	Ensembl	panpan1.1		panPan2

RGS20
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	5,520,858 - 5,606,028 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	5,521,641 - 5,605,405 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	5,896,985 - 5,981,029 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	5,600,289 - 5,682,211 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	5,600,562 - 5,682,211 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	5,558,943 - 5,618,770 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	5,741,151 - 5,824,526 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	5,823,542 - 5,907,602 (+)	NCBI		UU_Cfam_GSD_1.0

Rgs20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	73,919,030 - 73,990,753 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	794,945 - 864,234 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	794,968 - 864,714 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RGS20
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	77,141,945 - 77,209,533 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	77,141,935 - 77,185,209 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	84,213,610 - 84,280,766 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RGS20
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	49,934,043 - 50,041,914 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	49,934,940 - 50,041,051 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	91,897,557 - 92,005,525 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rgs20
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624735	1,710,957 - 1,785,400 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rgs20
872 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	255
Count of miRNA genes:	177
Interacting mature miRNAs:	199
Transcripts:	ENSRNOT00000010682
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
2312562	Pur18	Proteinuria QTL 18	2.6	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	5	2138965	32656739	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	2282226	69540447	Rat
2313085	Bss59	Bone structure and strength QTL 59	2.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	5	3844018	26141981	Rat
1300117	Hrtrt8	Heart rate QTL 8	3.49		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	3844018	47869213	Rat
61462	Niddm10	Non-insulin dependent diabetes mellitus QTL 10	3.9	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	5	5112159	47171491	Rat
631827	Alc4	Alcohol consumption QTL 4	3.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	5	8187501	18616199	Rat
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	8948228	53948228	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	12689285	57689285	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat

Markers in Region

D5Got261

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	14,537,764 - 14,538,012 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	14,417,442 - 14,417,689	NCBI	Rnor6.0
Rnor_5.0	5	19,199,166 - 19,199,413	UniSTS	Rnor5.0
RGSC_v3.4	5	14,739,278 - 14,739,525	UniSTS	RGSC3.4
Celera	5	13,908,565 - 13,908,808	UniSTS
Cytogenetic Map	5	q12	UniSTS

D5Got205

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	14,541,210 - 14,541,363 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	14,420,888 - 14,421,040	NCBI	Rnor6.0
Rnor_5.0	5	19,202,612 - 19,202,764	UniSTS	Rnor5.0
RGSC_v3.4	5	14,742,724 - 14,742,876	UniSTS	RGSC3.4
Celera	5	13,912,007 - 13,912,159	UniSTS
Cytogenetic Map	5	q12	UniSTS

STS-D29495

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	14,571,390 - 14,571,445 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	14,451,066 - 14,451,120	NCBI	Rnor6.0
Rnor_5.0	5	19,232,789 - 19,232,843	UniSTS	Rnor5.0
RGSC_v3.4	5	14,773,927 - 14,773,981	UniSTS	RGSC3.4
Celera	5	13,942,213 - 13,942,267	UniSTS
Cytogenetic Map	5	q12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									50		13
Low	2		8		14				24	18	20	8
Below cutoff	1	25	18	10	5	10	8	9		16	3	3	8

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001127495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001402015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC160842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000010682 ⟹ ENSRNOP00000010682

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	14,536,164 - 14,614,084 (+)	Ensembl
Rnor_6.0 Ensembl	5	14,415,841 - 14,494,045 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089273 ⟹ ENSRNOP00000072419

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	14,415,606 - 14,494,756 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117278 ⟹ ENSRNOP00000085029

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	14,534,775 - 14,614,084 (+)	Ensembl

RefSeq Acc Id:

NM_001127495 ⟹ NP_001120967

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,334,261 - 19,412,122 (+)	NCBI
mRatBN7.2	5	14,536,450 - 14,614,317 (+)	NCBI
Rnor_6.0	5	14,415,841 - 14,493,744 (+)	NCBI
Rnor_5.0	5	19,197,565 - 19,275,548 (+)	NCBI
RGSC_v3.4	5	14,737,677 - 14,816,606 (+)	RGD
Celera	5	13,906,964 - 13,985,237 (+)	RGD

Sequence:

show sequence

CTAGCATCGCTTCATTCACAAGGTCCTAGCATTCATTCATGCGCTCTGGAAACTCCCCCATACA
CCCCCGCAAGCTAAAGCCAGGGAATAAAGAGAGAGAGAGCCTTGCATCAAAGCTCGCTCCCGCC
GCACCCCCTATTTCGCTGCGATTAGAAGAGAGGAGCCAAAATCGGGGCTCCGCTGGCCCGCATT
AGGACTAGGGAGTACCCCTAGCCTCCGAGTGCTGCGCGCCGCCGCCAGAAGGAGGCGAGCCGGG
GAATTGCCCTGCCCTAGGAAAGCGGGCGCGGGGGCGGAGAGGAGTCACAGGAGGGAAAGGAGGA
GGAAGAGAGAAGAGCTCCGGAGCTTAGACCCAGAAACGTAGGAAAGGGCGGGAGGCAGAGAGCC
AGCGCGGGCGGAGTAGGAACCGCGCTTAAAGTGTAAGAAAACTAAGGCACACTCTAGACGCATG
CGCACGGCCAACGGAGGCCCGAGGGCCGGAGCTTCCCCTTCGGCTAGTCCAGAGGACCCTAACC
TGCCTGTGGAATCTGAGCAGACCGAAATGCGGATGCGGCAGATGTGCAGCGGAAGTGAGACGCA
GGGCTCTGTCCCAAGCCAGCAGCAGGGCGTGGGCGGCCGAGGCTCCAATGCCTGCTGCTTTTGC
TGGTGCTGCTGCTGCAGCTGTTCTTGCCTCACCGTCAGAAACCAAGAAGACCAGAGACCCCAAA
GAGCTGCCCACGAACTCAGAACAGACATTCCAGCGTGTGAAGAAAGCCCCATGCCCACTCTGGA
AGAAGTCTGTGCCTGGGCCCAATCTTTTGACAACCTAATGGTCACTCCAGCTGGAAGAAATGCA
TTCCGGGAATTTCTTCGAACAGAATTCAGTGAGGAAAACATGCTCTTCTGGATGGCCTGTGAGG
AACTGAAAAGGGAAGCTAATAAAAGCACTATTGAGGAGAAAGCAAGGATAATATATGAAGACTA
CATTTCTATTCTCTCTCCGAAAGAGGTCAGCCTGGACTCCCGAGTGCGAGAGGTTATCAACAGA
AACATGGTGGATCCATCTCAACACATCTTTGATGACGCTCAACTGCAGATCTACACCCTAATGC
ACAGAGACTCCTATCCCCGCTTCATGAACTCCACAGTCTATAAGGATTTACTTGAGTCCTTAGC
TGAGAAAGCAGTTGAAGCATAGGTGGTTTTGAATATATTTATTATTAACAAAACAAGAAAATAA
CTCATGGATTCCGTCTAGCACAGGGGATTTAGAGATAGGATGTCTTGTGCTACAGTGATTCTGA
CTGTTGTAATAACAGATTCTTCCTCCACGGAAAGTTCTCGATTCACAATGGAAATTGCAGCCAC
CTATAGCGATACTTATCAGACAAGAGGGCGGTGGGCATGACTGCCTTAGATAGTGTGCTCACAC
TCACAATAACAGTAGCATGTTCTCAGGGGCAGGGCATGCACTAGCCTCTGTTCTGCCTGAAGCA
TAGATATACAAGGAACAAATGGTAACACTTTGTTTTGCATGAGTTCAATACTATATTGCTCTCC
AAAGAAGTGGCATTCAAATCCTTCTCAACTAACCCTTCCCTCAGTCTGAATACTTTACTTGGCA
CCATGCCAGGTCTGAGAGTCACATCTCACAAAGATGTGACCATTCCTTGTAAAAATGGTGGAAA
CCTGTTC

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RefSeq Acc Id:

NM_001402015 ⟹ NP_001388944

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,282,249 - 19,412,122 (+)	NCBI
mRatBN7.2	5	14,484,436 - 14,614,317 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001120967	(Get FASTA)	NCBI Sequence Viewer
	NP_001388944	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI60842	(Get FASTA)	NCBI Sequence Viewer
	EDM11585	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010682
	ENSRNOP00000010682.4
	ENSRNOP00000085029.1

RefSeq Acc Id:	NP_001120967 ⟸ NM_001127495
- Peptide Label:	isoform 1
- UniProtKB:	G3V716 (UniProtKB/TrEMBL), A6JFI9 (UniProtKB/TrEMBL), B1H233 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRTANGGPRAGASPSASPEDPNLPVESEQTEMRMRQMCSGSETQGSVPSQQQGVGGRGSNACCF CWCCCCSCSCLTVRNQEDQRPQRAAHELRTDIPACEESPMPTLEEVCAWAQSFDNLMVTPAGRN AFREFLRTEFSEENMLFWMACEELKREANKSTIEEKARIIYEDYISILSPKEVSLDSRVREVIN RNMVDPSQHIFDDAQLQIYTLMHRDSYPRFMNSTVYKDLLESLAEKAVEA hide sequence

RefSeq Acc Id:

ENSRNOP00000072419 ⟸ ENSRNOT00000089273

RefSeq Acc Id:

ENSRNOP00000010682 ⟸ ENSRNOT00000010682

RefSeq Acc Id:

ENSRNOP00000085029 ⟸ ENSRNOT00000117278

RefSeq Acc Id:	NP_001388944 ⟸ NM_001402015
- Peptide Label:	isoform 2

Protein Domains

RGS

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V716-F1-model_v2	AlphaFold	G3V716	1-242	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1586146	AgrOrtholog
BioCyc Gene	G2FUF-42155	BioCyc
Ensembl Genes	ENSRNOG00000008100	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000010682	ENTREZGENE
	ENSRNOT00000010682.6	UniProtKB/TrEMBL
	ENSRNOT00000117278.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.167.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:8361585	IMAGE-MGC_LOAD
InterPro	Regulat_G_prot_signal_superfam	UniProtKB/TrEMBL
	RGS_sf	UniProtKB/TrEMBL
	RGS_subdomain_2	UniProtKB/TrEMBL
KEGG Report	rno:362477	UniProtKB/TrEMBL
MGC_CLONE	MGC:187568	IMAGE-MGC_LOAD
NCBI Gene	362477	ENTREZGENE
PANTHER	REGULATOR OF G PROTEIN SIGNALING	UniProtKB/TrEMBL
	REGULATOR OF G-PROTEIN SIGNALING 20	UniProtKB/TrEMBL
Pfam	RGS	UniProtKB/TrEMBL
PhenoGen	Rgs20	PhenoGen
PRINTS	RGSPROTEIN	UniProtKB/TrEMBL
PROSITE	RGS	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000008100	RatGTEx
SMART	RGS	UniProtKB/TrEMBL
Superfamily-SCOP	Regulat_G_prot_signal_superfam	UniProtKB/TrEMBL
UniProt	A0A8I6GBE3_RAT	UniProtKB/TrEMBL
	A6JFI9	ENTREZGENE, UniProtKB/TrEMBL
	B1H233	ENTREZGENE, UniProtKB/TrEMBL
	G3V716	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-05	Rgs20	regulator of G-protein signaling 20	LOC362477	similar to Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC362477	similar to Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar