Tma7 (translation machinery associated 7 homolog) - Rat Genome Database

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Gene: Tma7 (translation machinery associated 7 homolog) Rattus norvegicus
Analyze
Symbol: Tma7
Name: translation machinery associated 7 homolog
RGD ID: 1584795
Description: Orthologous to several human genes including TMA7B (translation machinery associated 7 homolog B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ccdc72; coiled-coil domain containing 72; coiled-coil domain-containing protein 72; hypothetical protein LOC679746; LOC679747; translation machinery associated 7 homolog (S. cerevisiae); translation machinery-associated protein 7; translational machinery associated 7 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,604,680 - 118,609,368 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,604,680 - 118,609,368 (-)EnsemblGRCr8
mRatBN7.28109,726,213 - 109,730,902 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,726,196 - 109,735,474 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,341,101 - 115,345,781 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,540,275 - 113,544,956 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,383,082 - 111,387,762 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,815,725 - 117,820,422 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,815,725 - 117,820,413 (-)Ensemblrn6Rnor6.0
Rnor_5.08117,167,470 - 117,172,158 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48114,090,959 - 114,095,761 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8109,017,504 - 109,022,192 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Tma7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,604,680 - 118,609,368 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,604,680 - 118,609,368 (-)EnsemblGRCr8
mRatBN7.28109,726,213 - 109,730,902 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,726,196 - 109,735,474 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,341,101 - 115,345,781 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,540,275 - 113,544,956 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,383,082 - 111,387,762 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,815,725 - 117,820,422 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,815,725 - 117,820,413 (-)Ensemblrn6Rnor6.0
Rnor_5.08117,167,470 - 117,172,158 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48114,090,959 - 114,095,761 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8109,017,504 - 109,022,192 (-)NCBICelera
Cytogenetic Map8q32NCBI
TMA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,440,257 - 48,444,208 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,440,213 - 48,444,218 (+)Ensemblhg38GRCh38
GRCh37348,481,667 - 48,485,616 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,456,690 - 48,460,541 (+)NCBIBuild 36Build 36hg18NCBI36
Celera348,432,457 - 48,436,308 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,535,990 - 48,539,688 (+)NCBIHuRef
CHM1_1348,433,970 - 48,437,822 (+)NCBICHM1_1
T2T-CHM13v2.0348,468,270 - 48,472,220 (+)NCBIT2T-CHM13v2.0
Tma7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,907,056 - 108,911,449 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,903,636 - 108,911,655 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm389109,077,988 - 109,082,381 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9109,074,568 - 109,082,587 (-)Ensemblmm10GRCm38
MGSCv379108,980,502 - 108,984,895 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369108,935,394 - 108,939,787 (-)NCBIMGSCv36mm8
Celera9108,636,789 - 108,641,235 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.63NCBI
Tma7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542016,389,256 - 16,389,553 (-)NCBIChiLan1.0ChiLan1.0
TMA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,415,033 - 48,419,071 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,419,865 - 48,423,839 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,362,222 - 48,366,235 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,445,038 - 49,448,342 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,445,111 - 49,448,009 (+)EnsemblpanPan2panpan1.1
TMA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12740,713,865 - 40,714,228 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2740,713,879 - 40,714,073 (+)EnsemblcanFam3CanFam3.1
ROS_Cfam_1.02741,069,789 - 41,070,176 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2741,069,815 - 41,070,009 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12741,007,478 - 41,007,869 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02740,982,902 - 40,983,284 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,379,206 - 5,379,602 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC110599066
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X12,497,962 - 12,498,310 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936624659,521 - 659,879 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100521518
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,153,629 - 31,156,339 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11331,153,614 - 31,156,339 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,418,084 - 34,420,799 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103227881
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,955,816 - 30,956,320 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041135,831,875 - 135,832,328 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tma7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X8,472,827 - 8,473,286 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tma7
28 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:165
Count of miRNA genes:86
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000068775, ENSRNOT00000075819
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH140669  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000075819   ⟹   ENSRNOP00000065251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,604,680 - 118,609,368 (-)Ensembl
mRatBN7.2 Ensembl8109,726,196 - 109,730,902 (-)Ensembl
Rnor_6.0 Ensembl8117,815,725 - 117,820,413 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119465   ⟹   ENSRNOP00000080908
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8109,726,213 - 109,735,474 (-)Ensembl
RefSeq Acc Id: NM_001126048   ⟹   NP_001119520
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,604,680 - 118,609,368 (-)NCBI
mRatBN7.28109,726,213 - 109,730,902 (-)NCBI
Rnor_6.08117,815,725 - 117,820,413 (-)NCBI
Rnor_5.08117,167,470 - 117,172,158 (-)NCBI
RGSC_v3.48114,090,959 - 114,095,761 (-)RGD
Celera8109,017,504 - 109,022,192 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001119520 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77113 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065251
  ENSRNOP00000065251.4
RefSeq Acc Id: NP_001119520   ⟸   NM_001126048
- UniProtKB: A6I3B4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065251   ⟸   ENSRNOT00000075819
Ensembl Acc Id: ENSRNOP00000080908   ⟸   ENSRNOT00000119465

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZW2-F1-model_v2 AlphaFold D3ZZW2 1-64 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696322
Promoter ID:EPDNEW_R6847
Type:multiple initiation site
Name:Tma7_1
Description:translation machinery associated 7 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,820,399 - 117,820,459EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584795 AgrOrtholog
BioCyc Gene G2FUF-29091 BioCyc
Ensembl Genes ENSRNOG00000047225 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075819 ENTREZGENE
  ENSRNOT00000075819.4 UniProtKB/TrEMBL
InterPro TMA7 UniProtKB/TrEMBL
KEGG Report rno:679747 UniProtKB/TrEMBL
NCBI Gene 679747 ENTREZGENE
PANTHER PTHR28632 UniProtKB/TrEMBL
Pfam TMA7 UniProtKB/TrEMBL
PhenoGen Tma7 PhenoGen
RatGTEx ENSRNOG00000047225 RatGTEx
UniProt A6I3B4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZW2_RAT UniProtKB/TrEMBL
UniProt Secondary M0R734 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-01 Tma7  translation machinery associated 7 homolog  Tma7  translation machinery associated 7 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-06-08 Tma7  translation machinery associated 7 homolog (S. cerevisiae)  Tma7  translational machinery associated 7 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-09-25 Tma7  translational machinery associated 7 homolog  Ccdc72  coiled-coil domain containing 72  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Ccdc72  coiled-coil domain containing 72  LOC679747  hypothetical protein LOC679746  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC679747  hypothetical protein LOC679746  LOC686398  hypothetical protein LOC686398  Data merged from RGD:1583108 1643240 APPROVED
2006-11-19 LOC679747  hypothetical protein LOC679746      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC686398  hypothetical protein LOC686398      Symbol and Name status set to provisional 70820 PROVISIONAL