Tmem201 (transmembrane protein 201) - Rat Genome Database

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Gene: Tmem201 (transmembrane protein 201) Rattus norvegicus
Analyze
Symbol: Tmem201
Name: transmembrane protein 201
RGD ID: 1583947
Description: Predicted to enable actin filament binding activity and lamin binding activity. Predicted to be involved in several processes, including nuclear migration along microtubule; positive regulation of endothelial cell migration; and protein localization to nuclear envelope. Predicted to act upstream of or within fibroblast migration and nuclear migration. Predicted to be located in cortical endoplasmic reticulum; nuclear inner membrane; and spindle pole centrosome. Predicted to be active in nuclear membrane. Orthologous to human TMEM201 (transmembrane protein 201); INTERACTS WITH amphetamine; atrazine; endosulfan.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313720; LOC691426; similar to CG7744-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85165,449,270 - 165,471,901 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5165,449,858 - 165,471,922 (-)EnsemblGRCr8
mRatBN7.25160,166,240 - 160,188,874 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5160,166,427 - 160,188,843 (-)EnsemblmRatBN7.2
Rnor_6.05166,672,700 - 166,695,288 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,672,450 - 166,695,134 (-)Ensemblrn6Rnor6.0
Rnor_5.05170,317,114 - 170,339,696 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45166,809,346 - 166,830,271 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5158,435,362 - 158,457,987 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
actin filament binding  (IBA,IEA,ISO)
lamin binding  (IBA,IEA,ISO)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19494128   PMID:21610090   PMID:22349700   PMID:27541860  


Genomics

Comparative Map Data
Tmem201
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85165,449,270 - 165,471,901 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5165,449,858 - 165,471,922 (-)EnsemblGRCr8
mRatBN7.25160,166,240 - 160,188,874 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5160,166,427 - 160,188,843 (-)EnsemblmRatBN7.2
Rnor_6.05166,672,700 - 166,695,288 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,672,450 - 166,695,134 (-)Ensemblrn6Rnor6.0
Rnor_5.05170,317,114 - 170,339,696 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45166,809,346 - 166,830,271 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5158,435,362 - 158,457,987 (-)NCBICelera
Cytogenetic Map5q36NCBI
TMEM201
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819,588,911 - 9,614,877 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19,588,721 - 9,614,877 (+)Ensemblhg38GRCh38
GRCh3719,648,969 - 9,674,935 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619,571,567 - 9,587,594 (+)NCBIBuild 36Build 36hg18NCBI36
Celera18,762,143 - 8,781,135 (+)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef18,799,790 - 8,825,673 (+)NCBIHuRef
CHM1_119,637,484 - 9,663,494 (+)NCBICHM1_1
T2T-CHM13v2.019,125,255 - 9,151,173 (+)NCBIT2T-CHM13v2.0
Tmem201
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394149,799,832 - 149,822,501 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4149,799,832 - 149,822,501 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384149,715,375 - 149,738,072 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4149,715,375 - 149,738,044 (-)Ensemblmm10GRCm38
MGSCv374149,089,493 - 149,112,145 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364148,559,184 - 148,581,836 (-)NCBIMGSCv36mm8
Celera4151,981,567 - 152,004,232 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map480.15NCBI
Tmem201
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554863,882,813 - 3,900,780 (-)Ensembl
ChiLan1.0NW_0049554863,881,571 - 3,900,879 (-)NCBIChiLan1.0ChiLan1.0
TMEM201
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21218,612,711 - 218,639,061 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11217,257,346 - 217,283,703 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v018,349,271 - 8,375,601 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.119,583,400 - 9,606,331 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl19,583,400 - 9,606,331 (+)EnsemblpanPan2panpan1.1
TMEM201
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1562,831,449 - 62,853,437 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl562,834,884 - 62,851,467 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha562,844,626 - 62,869,026 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0563,055,557 - 63,079,960 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl563,055,372 - 63,077,941 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1563,077,401 - 63,101,787 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0562,916,460 - 62,941,005 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0563,320,452 - 63,344,878 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tmem201
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505833,122,244 - 33,144,928 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366233,613,218 - 3,628,688 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366233,612,845 - 3,629,661 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM201
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl669,973,397 - 69,998,544 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1669,973,378 - 69,998,548 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2664,119,037 - 64,144,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM201
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120122,155,430 - 122,181,624 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20122,157,166 - 122,181,446 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605426,121,719 - 26,147,883 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem201
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248182,816,845 - 2,835,524 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248182,817,083 - 2,835,468 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Tmem201
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1111,028,268 - 11,050,597 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tmem201
31 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:217
Count of miRNA genes:152
Interacting mature miRNAs:172
Transcripts:ENSRNOT00000047763, ENSRNOT00000066748
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5160111176171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5160071170172129029Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5156396728167181764Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat

Markers in Region
RH142942  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25160,175,737 - 160,175,859 (+)MAPPERmRatBN7.2
Rnor_6.05166,682,198 - 166,682,319NCBIRnor6.0
Rnor_5.05170,326,612 - 170,326,733UniSTSRnor5.0
RGSC_v3.45166,817,255 - 166,817,376UniSTSRGSC3.4
Celera5158,444,860 - 158,444,981UniSTS
RH 3.4 Map51120.3UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 92 59 6 356 192 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000047763   ⟹   ENSRNOP00000048083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5165,449,858 - 165,471,880 (-)Ensembl
mRatBN7.2 Ensembl5160,166,427 - 160,188,843 (-)Ensembl
Rnor_6.0 Ensembl5166,672,450 - 166,695,134 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000161231   ⟹   ENSRNOP00000107178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5165,449,858 - 165,471,922 (-)Ensembl
RefSeq Acc Id: XM_001078224   ⟹   XP_001078224
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,449,270 - 165,471,901 (-)NCBI
mRatBN7.25160,166,240 - 160,188,874 (-)NCBI
Rnor_6.05166,672,700 - 166,695,288 (-)NCBI
Rnor_5.05170,317,114 - 170,339,696 (-)NCBI
RGSC_v3.45166,809,346 - 166,830,271 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001418231 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418232 (Get FASTA)   NCBI Sequence Viewer  
  XP_001078224 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048083
  ENSRNOP00000048083.5
  ENSRNOP00000107178.1
RefSeq Acc Id: XP_001078224   ⟸   XM_001078224
- Sequence:
Ensembl Acc Id: ENSRNOP00000048083   ⟸   ENSRNOT00000047763
Ensembl Acc Id: ENSRNOP00000107178   ⟸   ENSRNOT00000161231
Protein Domains
Ima1 N-terminal   Transmembrane protein 201 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZBW3-F1-model_v2 AlphaFold D3ZBW3 1-620 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1583947 AgrOrtholog
BioCyc Gene G2FUF-39117 BioCyc
Ensembl Genes ENSRNOG00000023152 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047763 ENTREZGENE
  ENSRNOT00000047763.8 UniProtKB/TrEMBL
  ENSRNOT00000161231.1 UniProtKB/TrEMBL
InterPro DUF2349 UniProtKB/TrEMBL
  DUF2448_C UniProtKB/TrEMBL
  TMEM201 UniProtKB/TrEMBL
KEGG Report rno:691426 UniProtKB/TrEMBL
NCBI Gene 691426 ENTREZGENE
PANTHER PTHR28646 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 201 UniProtKB/TrEMBL
Pfam DUF2349 UniProtKB/TrEMBL
  DUF2448 UniProtKB/TrEMBL
PhenoGen Tmem201 PhenoGen
RatGTEx ENSRNOG00000023152 RatGTEx
UniProt A0ABK0L9V8_RAT UniProtKB/TrEMBL
  A6IUC1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBW3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-10-22 Tmem201  transmembrane protein 201  LOC691426  similar to CG7744-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC691426  similar to CG7744-PA  RGD1306651_predicted  similar to CG7744-PA (predicted)  Data merged from RGD:1306651 1643240 APPROVED
2006-11-19 LOC691426  similar to CG7744-PA      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1306651_predicted  similar to CG7744-PA (predicted)  LOC313720_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313720_predicted  similar to CG7744-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL