Zfp469 (zinc finger protein 469) - Rat Genome Database

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Gene: Zfp469 (zinc finger protein 469) Rattus norvegicus
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Symbol: Zfp469
Name: zinc finger protein 469
RGD ID: 1583874
Description: Human ortholog(s) of this gene implicated in brittle cornea syndrome 1. Orthologous to human ZNF469 (zinc finger protein 469); INTERACTS WITH 17beta-estradiol; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC691499; similar to Zinc finger protein 469; Zfp469-ps1; zinc finger protein 469, pseudogene 1; Znf469; Znf469-ps1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,190,901 - 67,232,569 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1967,190,901 - 67,232,569 (+)EnsemblGRCr8
mRatBN7.21950,282,337 - 50,324,010 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1957,075,429 - 57,117,094 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01957,757,281 - 57,798,955 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01959,974,031 - 60,015,706 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01954,843,864 - 55,083,935 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01965,758,945 - 65,800,160 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41952,474,513 - 52,514,139 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1949,329,658 - 49,566,287 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Zfp469
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,190,901 - 67,232,569 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1967,190,901 - 67,232,569 (+)EnsemblGRCr8
mRatBN7.21950,282,337 - 50,324,010 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1957,075,429 - 57,117,094 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01957,757,281 - 57,798,955 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01959,974,031 - 60,015,706 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01954,843,864 - 55,083,935 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01965,758,945 - 65,800,160 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41952,474,513 - 52,514,139 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1949,329,658 - 49,566,287 (+)NCBICelera
Cytogenetic Map19q12NCBI
ZNF469
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,100,931 - 88,440,753 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,382,959 - 88,440,757 (+)Ensemblhg38GRCh38
GRCh371688,449,367 - 88,507,161 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,021,380 - 87,034,666 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1673,564,290 - 73,577,602 (+)NCBICelera
Cytogenetic Map16q24.2NCBI
HuRef1674,187,210 - 74,200,522 (+)NCBIHuRef
CHM1_11689,905,133 - 89,918,418 (+)NCBICHM1_1
T2T-CHM13v2.01694,449,769 - 94,508,741 (+)NCBIT2T-CHM13v2.0
Zfp469
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398122,770,009 - 122,999,389 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8122,985,359 - 122,999,389 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388122,043,123 - 122,272,650 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,258,620 - 122,272,650 (+)Ensemblmm10GRCm38
MGSCv378124,783,967 - 124,796,550 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368125,146,157 - 125,158,740 (+)NCBIMGSCv36mm8
Celera8126,489,037 - 126,501,620 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.85NCBI
Znf469
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555412,404,549 - 2,438,183 (+)NCBIChiLan1.0ChiLan1.0
ZNF469
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21897,864,686 - 98,210,176 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116103,781,045 - 104,124,393 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01668,777,496 - 69,151,995 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11688,800,542 - 88,816,811 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1688,803,202 - 88,815,390 (+)EnsemblpanPan2panpan1.1
ZNF469
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,887,534 - 64,903,553 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,897,119 - 64,909,874 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0565,106,202 - 65,118,957 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl565,107,572 - 65,118,884 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1565,131,802 - 65,144,557 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,963,589 - 64,976,332 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,370,098 - 65,382,853 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Znf469
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,439,524 - 25,454,515 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366411,193,085 - 1,205,283 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF469
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,162,822 - 1,174,257 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.161,161,514 - 1,208,406 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ZNF469
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1573,762,456 - 73,820,262 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660471,866,974 - 1,926,024 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf469
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247461,043,117 - 1,074,776 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Znf469
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11741,890,954 - 41,902,845 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:60
Interacting mature miRNAs:65
Transcripts:ENSRNOT00000038203
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
D19Got111  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21950,300,071 - 50,300,243 (+)MAPPERmRatBN7.2
Rnor_6.01955,060,310 - 55,060,477NCBIRnor6.0
Rnor_5.01965,776,535 - 65,776,702UniSTSRnor5.0
RGSC_v3.41952,491,531 - 52,491,698UniSTSRGSC3.4
Celera1949,542,354 - 49,542,521UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 17 32 35 89 62 11 31 20 32 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000163835   ⟹   ENSRNOP00000102075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1967,190,901 - 67,232,569 (+)Ensembl
RefSeq Acc Id: NM_001401088   ⟹   NP_001388017
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81967,190,901 - 67,232,569 (+)NCBI
mRatBN7.21950,282,337 - 50,324,010 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001388017 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000102075
  ENSRNOP00000102075.1
RefSeq Acc Id: NP_001388017   ⟸   NM_001401088
Ensembl Acc Id: ENSRNOP00000102075   ⟸   ENSRNOT00000163835

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1583874 AgrOrtholog
BioCyc Gene G2FUF-5407 BioCyc
Ensembl Genes ENSRNOG00000084845 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000163835 ENTREZGENE
  ENSRNOT00000163835.1 UniProtKB/TrEMBL
NCBI Gene 691499 ENTREZGENE
PhenoGen Zfp469 PhenoGen
RatGTEx ENSRNOG00000084845 RatGTEx
UniProt A0ABK0LA96_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-07 Zfp469  zinc finger protein 469  Zfp469-ps1  zinc finger protein 469, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-11-27 Zfp469-ps1  zinc finger protein 469, pseudogene 1  Znf469-ps1  zinc finger protein 469, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-02-24 Znf469-ps1  zinc finger protein 469, pseudogene 1  Znf469  zinc finger protein 469  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-19 Znf469  zinc finger protein 469  LOC691499  similar to Zinc finger protein 469  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC691499  similar to Zinc finger protein 469  LOC687587  similar to Zinc finger protein 469  Data merged from RGD:1584178 1643240 APPROVED
2006-11-19 LOC691499  similar to Zinc finger protein 469      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC687587  similar to Zinc finger protein 469      Symbol and Name status set to provisional 70820 PROVISIONAL