Plekhg1 (pleckstrin homology and RhoGEF domain containing G1) - Rat Genome Database

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Pathways
Gene: Plekhg1 (pleckstrin homology and RhoGEF domain containing G1) Rattus norvegicus
Analyze
Symbol: Plekhg1
Name: pleckstrin homology and RhoGEF domain containing G1
RGD ID: 1583676
Description: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be located in cytosol. Orthologous to human PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC679812; pleckstrin homology domain containing, family G (with RhoGef domain) member 1; pleckstrin homology domain-containing family G member 1; similar to Pleckstrin homology domain-containing family G member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8142,612,023 - 42,841,727 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl142,612,122 - 42,841,719 (+)EnsemblGRCr8
mRatBN7.2140,348,684 - 40,434,063 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl140,311,221 - 40,434,063 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx140,875,690 - 40,961,087 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,862,884 - 46,948,285 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0140,951,325 - 41,036,723 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0140,286,908 - 40,521,395 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl140,389,638 - 40,520,447 (+)Ensemblrn6Rnor6.0
Rnor_5.0141,637,081 - 41,868,666 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4134,591,855 - 34,677,812 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera136,040,218 - 36,125,350 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-nicotine  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
formaldehyde  (ISO)
gardiquimod  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
morphine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nicotine  (ISO)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
phenylmercury acetate  (ISO)
potassium dichromate  (ISO)
protein kinase inhibitor  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Plekhg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8142,612,023 - 42,841,727 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl142,612,122 - 42,841,719 (+)EnsemblGRCr8
mRatBN7.2140,348,684 - 40,434,063 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl140,311,221 - 40,434,063 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx140,875,690 - 40,961,087 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,862,884 - 46,948,285 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0140,951,325 - 41,036,723 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0140,286,908 - 40,521,395 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl140,389,638 - 40,520,447 (+)Ensemblrn6Rnor6.0
Rnor_5.0141,637,081 - 41,868,666 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4134,591,855 - 34,677,812 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera136,040,218 - 36,125,350 (+)NCBICelera
Cytogenetic Map1p11NCBI
PLEKHG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386150,599,885 - 150,843,665 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6150,599,848 - 150,843,665 (+)Ensemblhg38GRCh38
GRCh376150,921,021 - 151,164,801 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366150,962,692 - 151,206,492 (+)NCBIBuild 36Build 36hg18NCBI36
Build 346151,217,894 - 151,256,913NCBI
Celera6151,655,965 - 151,898,659 (+)NCBICelera
Cytogenetic Map6q25.1NCBI
HuRef6148,515,324 - 148,728,369 (+)NCBIHuRef
CHM1_16151,184,815 - 151,428,538 (+)NCBICHM1_1
T2T-CHM13v2.06151,800,395 - 152,044,215 (+)NCBIT2T-CHM13v2.0
Plekhg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39103,690,206 - 3,917,303 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl103,690,364 - 3,917,303 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38103,740,251 - 3,967,303 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl103,740,364 - 3,967,303 (+)Ensemblmm10GRCm38
MGSCv37106,379,238 - 6,606,164 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36106,381,992 - 6,473,874 (-)NCBIMGSCv36mm8
Celera103,669,512 - 3,895,132 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.06NCBI
Plekhg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543910,636,381 - 10,746,745 (-)Ensembl
ChiLan1.0NW_00495543910,636,444 - 10,755,814 (-)NCBIChiLan1.0ChiLan1.0
PLEKHG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25170,618,043 - 170,864,097 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16168,511,574 - 168,755,296 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06148,411,676 - 148,657,616 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16153,169,535 - 153,362,070 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6153,240,586 - 153,362,070 (+)EnsemblpanPan2panpan1.1
PLEKHG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1141,073,748 - 41,297,380 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl141,072,500 - 41,295,138 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha141,914,652 - 42,138,831 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0141,258,670 - 41,482,473 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl141,313,940 - 41,479,995 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1141,133,917 - 41,357,417 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0140,977,666 - 41,201,291 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0141,481,825 - 41,705,985 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Plekhg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946136,508,740 - 136,589,487 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364893,760,831 - 3,838,926 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364893,635,960 - 3,840,877 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl115,341,638 - 15,587,590 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1115,341,634 - 15,588,224 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PLEKHG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11378,034,968 - 78,285,288 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1378,154,150 - 78,287,996 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604050,337,476 - 50,580,807 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247857,338,592 - 7,513,435 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247857,340,310 - 7,590,385 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Plekhg1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12198,556,641 - 198,753,959 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Plekhg1
1444 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:30
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000021471
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat

Markers in Region
D1Rat11  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8142,666,497 - 42,666,672 (+)Marker Load Pipeline
mRatBN7.2140,260,422 - 40,260,599 (+)MAPPERmRatBN7.2
Rnor_6.0140,341,683 - 40,341,857NCBIRnor6.0
Rnor_5.0141,691,700 - 41,691,874UniSTSRnor5.0
RGSC_v3.4134,504,756 - 34,504,931RGDRGSC3.4
RGSC_v3.4134,504,757 - 34,504,931UniSTSRGSC3.4
Celera135,958,211 - 35,958,385UniSTS
RGSC_v3.1134,507,701 - 34,507,876RGD
SHRSP x BN Map118.23UniSTS
SHRSP x BN Map118.23RGD
FHH x ACI Map126.8199RGD
Cytogenetic Map1p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 57 59 6 319 157 11 138 79 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001190999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000021471   ⟹   ENSRNOP00000021471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl142,754,638 - 42,841,719 (+)Ensembl
mRatBN7.2 Ensembl140,311,221 - 40,434,063 (+)Ensembl
Rnor_6.0 Ensembl140,389,638 - 40,520,447 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000145879   ⟹   ENSRNOP00000101279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl142,612,122 - 42,841,719 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146329   ⟹   ENSRNOP00000099762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl142,612,144 - 42,841,719 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146696   ⟹   ENSRNOP00000102039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl142,754,347 - 42,841,719 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158133   ⟹   ENSRNOP00000111238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl142,746,761 - 42,841,719 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000160535   ⟹   ENSRNOP00000101116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl142,717,096 - 42,841,719 (+)Ensembl
RefSeq Acc Id: NM_001190999   ⟹   NP_001177928
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,754,740 - 42,839,480 (+)NCBI
mRatBN7.2140,348,684 - 40,434,063 (+)NCBI
Rnor_6.0140,433,990 - 40,519,148 (+)NCBI
Rnor_5.0141,637,081 - 41,868,666 (+)NCBI
Celera136,040,218 - 36,125,350 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063273299   ⟹   XP_063129369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,612,026 - 42,841,727 (+)NCBI
RefSeq Acc Id: XM_063273303   ⟹   XP_063129373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,745,302 - 42,841,727 (+)NCBI
RefSeq Acc Id: XM_063273307   ⟹   XP_063129377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,612,026 - 42,841,727 (+)NCBI
RefSeq Acc Id: XM_063273310   ⟹   XP_063129380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,612,311 - 42,841,727 (+)NCBI
RefSeq Acc Id: XM_063273314   ⟹   XP_063129384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,645,317 - 42,841,727 (+)NCBI
RefSeq Acc Id: XM_063273318   ⟹   XP_063129388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,740,523 - 42,841,727 (+)NCBI
RefSeq Acc Id: XM_063273321   ⟹   XP_063129391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,612,311 - 42,841,727 (+)NCBI
RefSeq Acc Id: XM_063273325   ⟹   XP_063129395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,612,023 - 42,838,015 (+)NCBI
RefSeq Acc Id: XM_063273333   ⟹   XP_063129403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,817,869 - 42,841,727 (+)NCBI
RefSeq Acc Id: XR_010057385
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,612,023 - 42,838,411 (+)NCBI
RefSeq Acc Id: NP_001177928   ⟸   NM_001190999
- UniProtKB: D4AE81 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021471   ⟸   ENSRNOT00000021471
RefSeq Acc Id: XP_063129395   ⟸   XM_063273325
- Peptide Label: isoform X2
- UniProtKB: A6KIK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129377   ⟸   XM_063273307
- Peptide Label: isoform X1
- UniProtKB: D4AE81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129369   ⟸   XM_063273299
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063129391   ⟸   XM_063273321
- Peptide Label: isoform X1
- UniProtKB: D4AE81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129380   ⟸   XM_063273310
- Peptide Label: isoform X1
- UniProtKB: D4AE81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129384   ⟸   XM_063273314
- Peptide Label: isoform X1
- UniProtKB: D4AE81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129388   ⟸   XM_063273318
- Peptide Label: isoform X1
- UniProtKB: D4AE81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129373   ⟸   XM_063273303
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063129403   ⟸   XM_063273333
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000111238   ⟸   ENSRNOT00000158133
Ensembl Acc Id: ENSRNOP00000101279   ⟸   ENSRNOT00000145879
Ensembl Acc Id: ENSRNOP00000102039   ⟸   ENSRNOT00000146696
Ensembl Acc Id: ENSRNOP00000101116   ⟸   ENSRNOT00000160535
Ensembl Acc Id: ENSRNOP00000099762   ⟸   ENSRNOT00000146329
Protein Domains
DH   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AE81-F1-model_v2 AlphaFold D4AE81 1-1453 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1583676 AgrOrtholog
BioCyc Gene G2FUF-61727 BioCyc
Ensembl Genes ENSRNOG00000016011 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021471.8 UniProtKB/TrEMBL
  ENSRNOT00000145879 ENTREZGENE
  ENSRNOT00000145879.1 UniProtKB/TrEMBL
  ENSRNOT00000146329.1 UniProtKB/TrEMBL
  ENSRNOT00000146696.1 UniProtKB/TrEMBL
  ENSRNOT00000158133.1 UniProtKB/TrEMBL
  ENSRNOT00000160535.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  PH_PLEKHG1_G2_G3 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  SOS1_NGEF_PH UniProtKB/TrEMBL
NCBI Gene 679812 ENTREZGENE
PANTHER FI17866P1 UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 1 UniProtKB/TrEMBL
Pfam RhoGEF UniProtKB/TrEMBL
  SOS1_NGEF_PH UniProtKB/TrEMBL
PhenoGen Plekhg1 PhenoGen
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016011 RatGTEx
SMART RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A0ABK0KY06_RAT UniProtKB/TrEMBL
  A0ABK0LDE0_RAT UniProtKB/TrEMBL
  A0ABK0LJM1_RAT UniProtKB/TrEMBL
  A0ABK0LK22_RAT UniProtKB/TrEMBL
  A0ABK0LKV1_RAT UniProtKB/TrEMBL
  A6KIK4 ENTREZGENE, UniProtKB/TrEMBL
  D4AE81 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-30 Plekhg1  pleckstrin homology and RhoGEF domain containing G1  Plekhg1  pleckstrin homology domain containing, family G (with RhoGef domain) member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-07-08 Plekhg1  pleckstrin homology domain containing, family G (with RhoGef domain) member 1  LOC683298  similar to Pleckstrin homology domain-containing family G member 1  Data merged from RGD:1589186 1643240 APPROVED
2008-03-05 Plekhg1  pleckstrin homology domain containing, family G (with RhoGef domain) member 1  LOC679812  similar to Pleckstrin homology domain-containing family G member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC679812  similar to Pleckstrin homology domain-containing family G member 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683298  similar to Pleckstrin homology domain-containing family G member 1      Symbol and Name status set to provisional 70820 PROVISIONAL