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Gene: Klhl14 (kelch-like family member 14) Rattus norvegicus

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Symbol:

Klhl14

Name:

kelch-like family member 14

RGD ID:

1566178

Description:

Predicted to be located in cytosol and endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum; neuron projection; and neuronal cell body. Orthologous to human KLHL14 (kelch like family member 14); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

kelch-like 14; kelch-like 14 (Drosophila); kelch-like protein 14; LOC364823; RGD1566178; similar to Kelch-like protein 14

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KLHL14 (kelch like family member 14)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Klhl14 (kelch-like 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Klhl14 (kelch like family member 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KLHL14 (kelch like family member 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KLHL14 (kelch like family member 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Klhl14 (kelch like family member 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KLHL14 (kelch like family member 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KLHL14 (kelch like family member 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Klhl14 (kelch like family member 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Klhl14 (kelch like family member 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	KCTD4 (potassium channel tetramerization domain containing 4)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	KLHL14 (kelch like family member 14)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Klhl14 (kelch-like 14)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	klhl14 (kelch-like family member 14)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	klhl14	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	13,079,159 - 13,192,728 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	13,079,159 - 13,193,557 (-)	Ensembl				GRCr8
mRatBN7.2	18	12,804,253 - 12,917,828 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	12,804,253 - 12,917,828 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	12,987,239 - 13,093,518 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	13,774,869 - 13,881,160 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	13,047,889 - 13,155,218 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	12,526,627 - 12,640,381 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	12,528,111 - 12,640,716 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	12,314,920 - 12,429,314 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	13,167,645 - 13,282,841 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	12,792,325 - 12,899,116 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,4-methylenedioxymethamphetamine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dimethyl sulfoxide (ISO)

dorsomorphin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

genistein (ISO)

GW 4064 (ISO)

leflunomide (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

panobinostat (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

progesterone (ISO)

quercetin (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sulfadimethoxine (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

tris(2-butoxyethyl) phosphate (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytosol (IEA,ISO)

endoplasmic reticulum (IBA,ISO)

endoplasmic reticulum membrane (IEA)

neuron projection (IBA,ISO)

neuronal cell body (IBA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19535332

Genomics

Comparative Map Data

Klhl14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	13,079,159 - 13,192,728 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	13,079,159 - 13,193,557 (-)	Ensembl				GRCr8
mRatBN7.2	18	12,804,253 - 12,917,828 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	12,804,253 - 12,917,828 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	12,987,239 - 13,093,518 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	13,774,869 - 13,881,160 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	13,047,889 - 13,155,218 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	12,526,627 - 12,640,381 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	12,528,111 - 12,640,716 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	12,314,920 - 12,429,314 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	13,167,645 - 13,282,841 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	12,792,325 - 12,899,116 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

KLHL14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	32,672,673 - 32,773,023 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	32,672,601 - 32,773,023 (-)	Ensembl			hg38	GRCh38
GRCh37	18	30,252,636 - 30,352,986 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	28,506,632 - 28,606,972 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	18	28,506,631 - 28,606,972	NCBI
Celera	18	27,060,909 - 27,161,231 (-)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI
HuRef	18	27,110,551 - 27,211,435 (-)	NCBI		HuRef
CHM1_1	18	30,180,386 - 30,280,718 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	32,864,443 - 32,964,769 (-)	NCBI		T2T-CHM13v2.0

Klhl14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	21,683,436 - 21,805,986 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	21,683,434 - 21,787,775 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	21,550,379 - 21,672,929 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	21,550,377 - 21,654,718 (-)	Ensembl			mm10	GRCm38
MGSCv37	18	21,708,878 - 21,810,869 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	21,693,387 - 21,795,378 (-)	NCBI		MGSCv36	mm8
Celera	18	22,050,010 - 22,152,573 (-)	NCBI		Celera
Cytogenetic Map	18	A2	NCBI
cM Map	18	11.96	NCBI

Klhl14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	19,841,194 - 19,932,774 (-)	Ensembl
ChiLan1.0	NW_004955402	19,841,255 - 19,932,774 (-)	NCBI	ChiLan1.0	ChiLan1.0

KLHL14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	50,050,211 - 50,151,722 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	35,742,809 - 35,844,315 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	25,880,582 - 26,003,452 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	29,474,625 - 29,575,074 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	29,476,607 - 29,572,911 (-)	Ensembl			panPan2	panpan1.1

KLHL14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	56,973,284 - 57,089,128 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	56,974,692 - 57,088,039 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	56,406,256 - 56,522,684 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	56,948,292 - 57,064,982 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	56,950,639 - 57,064,991 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	56,633,311 - 56,749,940 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	56,651,040 - 56,767,681 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	56,947,661 - 57,063,916 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Klhl14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	52,597,803 - 52,696,139 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936682	599,847 - 697,264 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936682	599,716 - 697,235 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KLHL14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	116,510,851 - 116,611,631 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	116,510,854 - 116,613,319 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	109,214,964 - 109,337,389 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KLHL14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	47,964,592 - 48,065,840 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	47,967,371 - 48,063,882 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	22,514,699 - 22,615,711 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Klhl14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	203,374 - 297,378 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624770	203,962 - 296,837 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Klhl14
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	15	22,060,412 - 22,162,133 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Klhl14
1042 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	1056
Count of miRNA genes:	322
Interacting mature miRNAs:	431
Transcripts:	ENSRNOT00000020697
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2301410	Bp317	Blood pressure QTL 317		0.004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	12219237	26822399	Rat
2301409	Cm70	Cardiac mass QTL 70		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	18	7065728	52065728	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	12216684	31644508	Rat
12904716	Am21	Aortic mass QTL 21		0.005	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	7065728	52065728	Rat
8552968	Pigfal19	Plasma insulin-like growth factor 1 level QTL 19	11.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	18	1	26032889	Rat
12904714	Cm131	Cardiac mass QTL 131		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	7065728	52065728	Rat
12904715	Cm132	Cardiac mass QTL 132		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	7065728	52065728	Rat
1331781	Scl28	Serum cholesterol level QTL 28	3.995		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	1	25071266	Rat
6903356	Bp354	Blood pressure QTL 354	4.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	15642423	Rat
6903345	Bp349	Blood pressure QTL 349	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5460455	42690191	Rat
6903349	Bp351	Blood pressure QTL 351	3.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
6903351	Bp352	Blood pressure QTL 352	3.3		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	12216684	31644508	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	44930869	Rat
12904680	Bw189	Body weight QTL 189		0.019	body mass (VT:0001259)	body weight (CMO:0000012)	18	12219237	26822399	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	12066482	57066482	Rat
1641910	Colcr3	Colorectal carcinoma resistance QTL 3	5.02	0.000007	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	1	25022372	Rat
12904693	Am20	Aortic mass QTL 20		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	12219237	26822399	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
12904695	Kidm73	Kidney mass QTL 73		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	12219237	26822399	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	3811902	30809809	Rat
12904689	Cm128	Cardiac mass QTL 128		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	12219237	26822399	Rat
12904690	Cm129	Cardiac mass QTL 129		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	12219237	26822399	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34566578	Rat
12904691	Cm130	Cardiac mass QTL 130		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	12219237	26822399	Rat
9590248	Scort10	Serum corticosterone level QTL 10	19.71	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	1	26032889	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4482648	49482648	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	54490981	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
11565454	Kidm59	Kidney mass QTL 59		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	7065728	52065728	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34566578	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	4307354	49307354	Rat

Markers in Region

D18Mit7

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	12,874,620 - 12,874,824 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	12,597,179 - 12,597,382	NCBI	Rnor6.0
Rnor_5.0	18	12,385,472 - 12,385,675	UniSTS	Rnor5.0
RGSC_v3.4	18	13,239,641 - 13,239,845	RGD	RGSC3.4
RGSC_v3.4	18	13,239,642 - 13,239,845	UniSTS	RGSC3.4
Celera	18	12,856,104 - 12,856,307	UniSTS
RGSC_v3.1	18	13,266,288 - 13,266,491	RGD
RH 3.4 Map	18	133.6	UniSTS
RH 3.4 Map	18	133.6	RGD
RH 2.0 Map	18	752.7	RGD
Cytogenetic Map	18	p12	UniSTS

D18Got14

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	12,874,644 - 12,874,930 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	12,597,203 - 12,597,488	NCBI	Rnor6.0
Rnor_5.0	18	12,385,496 - 12,385,781	UniSTS	Rnor5.0
RGSC_v3.4	18	13,239,665 - 13,239,951	RGD	RGSC3.4
RGSC_v3.4	18	13,239,666 - 13,239,951	UniSTS	RGSC3.4
Celera	18	12,856,128 - 12,856,413	UniSTS
RGSC_v3.1	18	13,266,312 - 13,266,597	RGD
RH 3.4 Map	18	141.5	UniSTS
RH 3.4 Map	18	141.5	RGD
RH 2.0 Map	18	744.5	RGD
Cytogenetic Map	18	p12	UniSTS

RH139706

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	12,919,202 - 12,919,420 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	12,641,756 - 12,641,973	NCBI	Rnor6.0
Rnor_5.0	18	12,430,049 - 12,430,266	UniSTS	Rnor5.0
RGSC_v3.4	18	13,284,216 - 13,284,433	UniSTS	RGSC3.4
Celera	18	12,900,491 - 12,900,708	UniSTS
RH 3.4 Map	18	133.3	UniSTS
Cytogenetic Map	18	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	4	18	138	61	59	29	88	29	4	258	135	11	112	81	89	30	12	12

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008771952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000020697 ⟹ ENSRNOP00000020697

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	13,079,159 - 13,192,728 (-)	Ensembl
mRatBN7.2 Ensembl	18	12,804,253 - 12,917,828 (-)	Ensembl
Rnor_6.0 Ensembl	18	12,528,111 - 12,640,716 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103990 ⟹ ENSRNOP00000090891

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	13,079,159 - 13,192,728 (-)	Ensembl
mRatBN7.2 Ensembl	18	12,804,253 - 12,917,828 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000123493 ⟹ ENSRNOP00000107410

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	13,079,159 - 13,192,699 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000127662 ⟹ ENSRNOP00000107856

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	13,079,159 - 13,193,557 (-)	Ensembl

RefSeq Acc Id:

NM_001108885 ⟹ NP_001102355

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	13,079,159 - 13,192,728 (-)	NCBI
mRatBN7.2	18	12,804,253 - 12,917,828 (-)	NCBI
Rnor_6.0	18	12,526,627 - 12,640,381 (-)	NCBI
Rnor_5.0	18	12,314,920 - 12,429,314 (-)	NCBI
RGSC_v3.4	18	13,167,645 - 13,282,841 (-)	RGD
Celera	18	12,792,325 - 12,899,116 (-)	RGD

Sequence:

show sequence

GCCCTGACTTTGCAGCTGGCTGACAGCAGGTTGGAGGAGGGTTTAAAGCCAGGTGCGCAGAGTC
AGCTCGCCATGTCCAGATCCGGGGACAGGACCTCCACCTTCGACCCCAGCCACAGTGACAACCT
GCTGCACGGTCTCAACCTGCTGTGGAGGAAGCAGCTATTTTGCGACGTGACCCTGACAGCCCAA
GGCCAACAGTTCCACTGCCACAAGGCCGTGCTGGCCTCCTGCTCGCAGTACTTCCGATCACTCT
TCTCCAGCCACCCCCCTCTCGGGGGAGGGGTCGGCGGCCAGGACGGCCTGGGGGCCCCCAAGGA
CCAGCAGCAGCAGCAGCAGCCGCAGCAGCAGCCTTCACAGCAGCAGCAGCAGCCACCACAGGAG
GAGCCCGGGACTCCTTCCTCCTCCCCCGACGACAAGCTGCTGACCAGTCCCCGAGCCATCAACA
ACCTAGTGCTGCAGGGCTGCTCGTCCATCGGGCTGCGCCTAGTGCTTGAATACCTCTACACGGC
CAACGTGACCCTGTCCCTGGACACCGTGGAGGAGGTGCTGTCGGTCAGCAAAATCCTGCACATT
CCTCAGGTCACCAAGCTCTGCGTTCAGTTCCTCAACGACCAGATCTCGGTGCAGAACTACAAGC
AGGTGTGCAAGATCGCCGCACTGCACGGCCTGGAGGAGACCAAGAAGCTGGCCAACAAGTACCT
GGTGGAGGATGTGCTGTTGCTTAACTTCGAGGAGATGCGTGCCCTGCTGGACTCGCTGCCGCCC
CCCGTGGAGTCGGAGCTGGCACTTTTCCAGATGTCCGTGCTGTGGCTGGAGCACGACCGTGAGA
CCCGCATGCAGTACGCGCCCGACCTCATGAAGCGCCTTCGCTTTGCGCTCATCCCCGCCCCGGA
GCTGGTGGAGCGGGTCCAGTCGGTGGATTTCATGCGCACCGACCCGGTCTGCCAGAAGCTGCTG
CTGGACGCCATGAACTACCACCTGATGCCCTTCAGGCAGCACTGCAGGCAGAGCCTGGCCAGCA
GAATTCGCTCTAACAAGAAAATGCTGCTGTTGGTTGGAGGGTTGCCTCCTGGACCAGACCGGCT
CCCCAGCAATCTGGTTCAGTATTATGACGACGAAAAGAAGACATGGAAAATACTCACAATTATG
CCTTACAACAGTGCCCACCACTGCGTTGTAGAGGTAGAAAACTTCCTGTTCGTGTTGGGTGGAG
AGGACCAGTGGAACCCAAATGGAAAACATAGTACAAATTTTGTCAGCCGATATGATCCCCGATT
TAATAGTTGGATTCAACTTCCACCCATGCAAGAAAGAAGAGCCAGTTTCTACGCATGTCGCTTG
GACAAGCATTTATATGTGATCGGCGGGAGGAACGAAACTGGCTACCTGTCCAGTGTGGAGTGCT
ACAACCTGGACACAAACGAGTGGCGCTATGTGTCGTCTCTGCCTCAGCCGCTGGCAGCCCACGC
AGGAGCAGTGCACAATGGGAAAATATACATTTCAGGGGGAGTGCACAACGGAGAGTATGTCCCG
TGGTTGTATTGTTATGACCCGGTCATGGATGTCTGGGCCCGCAAACAAGACATGAACACGAAGC
GTGCCATCCACACTCTGGCTGTGATGAACGATCGCTTGTATGCAATTGGAGGGAATCATTTGAA
AGGCTTCTCCCACCTAGACGTCATGCTTGTGGAGTGCTATGACCCAAAAGGTGACCAGTGGAAT
ATACTCCAAACACCCATCCTGGAGGGTCGAAGTGGGCCTGGCTGTGCGGTGCTCGATGACAGCA
TTTATCTAGTTGGAGGCTACAGCTGGAGTATGGGTGCCTACAAGTCCTCTACAATCTGCTATTG
TCCAGAAAAAGGAACCTGGACAGAACTCGAAGGCGATGTGGCTGAACCTCTGGCAGGCCCAGCC
TGTGCGACAGTCATTCTACCAGCCTGTGTGCCCTACAACAAATGACAGCAGGAAAGCCTGGCAT
AGTGCCACACCTAGAATGCAGGGACAGGCGGTGTGCTGTCCTGCGTGAACCATGCATTCCAATG
GTACAACTGCCCTAACCTTTGGTTTCTGATGACTTAAAAGTGACTTGCAGAAGAAAGAGACCCG
GCCTTGAGCAGAGACTGTTGTTTGCAACCCAGATGACACTCAACTTGTGGTGACAGACTCTTCC
ATATCAGGCCGGTTTGAACTTGTTCCACCTTTACGCAAACTCACGTGGAGCTGAACTTTCAAAA
AGGAAAAGATAAGCCACGGAAGCCTGGCCCCAGAGACCTAAGATCCATATTGTTGCATTGTTTC
CTAACTGCATGTGATAGACTCGGACATTTGGCAAATATTTTGTACATGAATGATTCAAAGTCCA
ACCCACGGAAATGGTCACCCTGTATTCCAGAAAGCGTCACTTGATTCTGTATTGGTAAATGCTT
GGCTTCTTCACCAACTCCATAGGTAGCAAAGGAAAACCACAGAAGAAGGAAGACAGGCATCTTT
GTTTCCACACAGTCATATTCTCTATCCCTTACAGCTTACCATGGGATCGGGAAAAAGTGAGTTG
GTGTCTTTGGTAATTGTTCTCTGCTAGAGAACAATTAATTGTGTGTCTTTGATACTCCTTGAAA
ATTAAAACTAAGTGCGCTCTGTTGCTTTTCAGCTCCCAGAAACTCATGCTTCCTCATTTCTTAT
GGGCATCTTAAGTAGTGAACATAGGACAATTTGCCTCAAGATAGAAGACCAACAACTCCATCAT
GAACTATCTCAGAAACTCTGTTAGATAGAAATTTGTTCCCAATCTAATCCATAATAAAAACTGA
CAAATCACTTTCAGAAATTCAGGTACACAAGGCAAACTTTCTCTCAAGTACAACCCAATTATCT
TTCTGATTCTTAAAACACATGACTTCCAGCTGAAGAGATGGCTCAGTGGTTCAAAGCACTTGCT
TCTCAGGCAGAGGACCTGGGTTTGGCTCTCAGCACCCATGTGGCGACTTACCACCATCCGTAAC
TCCAGATCCAGGGCACCCGTACATATGCAGTGCACTTACAAACTTGTAAACAAAACACTTGTAC
ACGTGAAATAAAAATAAATAACTCTTTTAAAATAATTATTTTTTAAAAAATGAACTTGCAAACT
CATAGTTCCTAATGGCCCACTTCCTCACCTCTGTCTGTCTGGCACCAGATTCCCGATTCTCATT
CTTCTTCCACTTACCCCATTGTTTTTTATCACTGGAGATGCCTGGACTTGGTCAAGAGAGTAAC
TTATTCTTGTTTTGAGGAACTGAAAACATAAAAGGATCAGGAGAGCATGACACGGTCTCTTTGT
GGCCAATCAGAAAAGCAAAACTAAGAAAAACATGAATTAGATTTTCAAGCTCATCTGAGTTTGA
CCAACACCGTTAGGCACTTCCAAGCACCTAAATATTTTTTTAAATCACAAAGAAATGTTGACCA
CCTTCAACAAATGTGATGTTAAAAATACCAAGTAGGGGTAGCCACAGATAAGAACAAATGCTTT
CATGGGAAGCTTCCACAATCACCTCAAGGTGGCTGGGCGTACCAGAATCCAACAACGTTTCTAC
AGAAAAGTGCAATCTTTGTTGTTTTTGTATTTATTTGTATGTTCAGATCCAAAGGATCTGTTGT
AAAAATATATATGTGAATATATATACATAACCAGTGCAATCAGCTTCCATTTCCTTTTTCTTGA
AAACACACGAATATATAGAAAGAAAGACAATAAGAACATGAGAAACGCCCACCGGCATCCCAGA
GAGAGCGAGCTGTTTCCAAAACTGTATTCTCAGCTGTTACAAGTCGCTGTTTATACAAGGGTAT
CGGCTTTTCCTTAGACTTGTTCCTTGCTTTATTTTTTATCACTAACCAAATTAAATAAAAGCAT
TTATGAGAACTCTAAAGCTTTCTGTATTTCAGAGAGATGCAAACTTCTAGAGTAAAAAGTGAAT
AAAAAGTCACAGAGGATGTAAATTTTGTACAGGACTAGGATGTAAATGAAGCTTGCTTGGAAGG
GGAAAAGTTTAAATAAAACTTTATGTACAAATTCGA

hide sequence

RefSeq Acc Id:

XM_039096999 ⟹ XP_038952927

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	13,079,159 - 13,190,859 (-)	NCBI
mRatBN7.2	18	12,804,253 - 12,915,948 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102355	(Get FASTA)	NCBI Sequence Viewer
	XP_038952927	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL76108	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020697
	ENSRNOP00000020697.5
	ENSRNOP00000090891.1
	ENSRNOP00000107410
	ENSRNOP00000107410.1
	ENSRNOP00000107856.1

RefSeq Acc Id:

NP_001102355 ⟸ NM_001108885

- UniProtKB:

D3ZYQ7 (UniProtKB/TrEMBL), A0A5S6R9P2 (UniProtKB/TrEMBL), A6J2H6 (UniProtKB/TrEMBL), A0A2I4HY32 (UniProtKB/TrEMBL), A0A8I6APG0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSS
HPPLGGGVGGQDGLGAPKDQQQQQQPQQQPSQQQQQPPQEEPGTPSSSPDDKLLTSPRAINNLV
LQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVC
KIAALHGLEETKKLANKYLVEDVLLLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRM
QYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIR
SNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQ
WNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKHLYVIGGRNETGYLSSVECYNL
DTNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAI
HTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYL
VGGYSWSMGAYKSSTICYCPEKGTWTELEGDVAEPLAGPACATVILPACVPYNK

hide sequence

Ensembl Acc Id:

ENSRNOP00000020697 ⟸ ENSRNOT00000020697

RefSeq Acc Id:	XP_038952927 ⟸ XM_039096999
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000090891 ⟸ ENSRNOT00000103990

Ensembl Acc Id:

ENSRNOP00000107410 ⟸ ENSRNOT00000123493

Ensembl Acc Id:

ENSRNOP00000107856 ⟸ ENSRNOT00000127662

Protein Domains

BTB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZYQ7-F1-model_v2	AlphaFold	D3ZYQ7	1-630	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1566178	AgrOrtholog
BioCyc Gene	G2FUF-8197	BioCyc
Ensembl Genes	ENSRNOG00000015418	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020697	ENTREZGENE
	ENSRNOT00000020697.8	UniProtKB/TrEMBL
	ENSRNOT00000103990.2	UniProtKB/TrEMBL
	ENSRNOT00000123493	ENTREZGENE
	ENSRNOT00000123493.1	UniProtKB/TrEMBL
	ENSRNOT00000127662.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.420	UniProtKB/TrEMBL
	2.120.10.80	UniProtKB/TrEMBL
	Potassium Channel Kv1.1, Chain A	UniProtKB/TrEMBL
InterPro	BACK	UniProtKB/TrEMBL
	BTB-kelch_protein	UniProtKB/TrEMBL
	BTB/POZ-like	UniProtKB/TrEMBL
	BTB/POZ_fold	UniProtKB/TrEMBL
	Kelch-typ_b-propeller	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
	KLHL14	UniProtKB/TrEMBL
	KLHL14_BACK	UniProtKB/TrEMBL
KEGG Report	rno:364823	UniProtKB/TrEMBL
NCBI Gene	364823	ENTREZGENE
PANTHER	LD33804P	UniProtKB/TrEMBL
	PTHR45632:SF6	UniProtKB/TrEMBL
Pfam	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
	Kelch_KLHDC2_KLHL20_DRC7	UniProtKB/TrEMBL
PhenoGen	Klhl14	PhenoGen
PIRSF	Kelch-like_protein_gigaxonin	UniProtKB/TrEMBL
PROSITE	BTB	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000015418	RatGTEx
SMART	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch	UniProtKB/TrEMBL
Superfamily-SCOP	BTB/POZ_fold	UniProtKB/TrEMBL
	SSF117281	UniProtKB/TrEMBL
UniProt	A0A2I4HY32	ENTREZGENE
	A0A5S6R9P2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6APG0	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LWF4_RAT	UniProtKB/TrEMBL
	A0ABK0LZ67_RAT	UniProtKB/TrEMBL
	A6J2H6	ENTREZGENE
	D3ZYQ7	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A2I4HY32	UniProtKB/TrEMBL
	A6J2H6	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-02-06	Klhl14	kelch-like family member 14	Klhl14	kelch-like 14 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Klhl14	kelch-like 14 (Drosophila)	RGD1566178_predicted	similar to Kelch-like protein 14 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1566178_predicted	similar to Kelch-like protein 14 (predicted)	LOC364823	similar to Kelch-like protein 14	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC364823	similar to Kelch-like protein 14			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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