KLHL14 (kelch like family member 14) - Rat Genome Database

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Gene: KLHL14 (kelch like family member 14) Pan paniscus
Analyze
Symbol: KLHL14
Name: kelch like family member 14
RGD ID: 11777691
Description: ASSOCIATED WITH intellectual disability (ortholog); FOUND IN actin cytoskeleton (inferred); aggresome (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kelch-like 14; kelch-like protein 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21750,050,211 - 50,151,722 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11835,742,809 - 35,844,315 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01825,880,582 - 26,003,452 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11829,474,625 - 29,575,074 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1829,476,607 - 29,572,911 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KLHL14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21750,050,211 - 50,151,722 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11835,742,809 - 35,844,315 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01825,880,582 - 26,003,452 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11829,474,625 - 29,575,074 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1829,476,607 - 29,572,911 (-)Ensemblpanpan1.1panPan2
KLHL14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381832,672,673 - 32,773,023 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1832,672,673 - 32,773,023 (-)EnsemblGRCh38hg38GRCh38
GRCh371830,252,636 - 30,352,986 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361828,506,632 - 28,606,972 (-)NCBINCBI36Build 36hg18NCBI36
Build 341828,506,631 - 28,606,972NCBI
Celera1827,060,909 - 27,161,231 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
HuRef1827,110,551 - 27,211,435 (-)NCBIHuRef
CHM1_11830,180,386 - 30,280,718 (-)NCBICHM1_1
T2T-CHM13v2.01832,864,443 - 32,964,769 (-)NCBIT2T-CHM13v2.0
Klhl14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391821,683,436 - 21,805,986 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1821,683,434 - 21,787,775 (-)EnsemblGRCm39 Ensembl
GRCm381821,550,379 - 21,672,929 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1821,550,377 - 21,654,718 (-)EnsemblGRCm38mm10GRCm38
MGSCv371821,708,878 - 21,810,869 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361821,693,387 - 21,795,378 (-)NCBIMGSCv36mm8
Celera1822,050,010 - 22,152,573 (-)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1811.96NCBI
Klhl14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81813,079,159 - 13,192,728 (-)NCBIGRCr8
mRatBN7.21812,804,253 - 12,917,828 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1812,804,253 - 12,917,828 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1812,987,239 - 13,093,518 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01813,774,869 - 13,881,160 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01813,047,889 - 13,155,218 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01812,526,627 - 12,640,381 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1812,528,111 - 12,640,716 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01812,314,920 - 12,429,314 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41813,167,645 - 13,282,841 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1812,792,325 - 12,899,116 (-)NCBICelera
Cytogenetic Map18p12NCBI
Klhl14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540219,841,194 - 19,932,774 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540219,841,255 - 19,932,774 (-)NCBIChiLan1.0ChiLan1.0
KLHL14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1756,973,284 - 57,089,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl756,974,692 - 57,088,039 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha756,406,256 - 56,522,684 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0756,948,292 - 57,064,982 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl756,950,639 - 57,064,991 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1756,633,311 - 56,749,940 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0756,651,040 - 56,767,681 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0756,947,661 - 57,063,916 (+)NCBIUU_Cfam_GSD_1.0
Klhl14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494452,597,803 - 52,696,139 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936682599,847 - 697,264 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936682599,716 - 697,235 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6116,510,851 - 116,611,631 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16116,510,854 - 116,613,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26109,214,964 - 109,337,389 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11847,964,592 - 48,065,840 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1847,967,371 - 48,063,882 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605022,514,699 - 22,615,711 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624770203,374 - 297,378 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624770203,962 - 296,837 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000061847   ⟹   ENSPPAP00000038938
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1829,476,607 - 29,572,911 (-)Ensembl
RefSeq Acc Id: XM_034943935   ⟹   XP_034799826
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21750,050,211 - 50,151,722 (-)NCBI
NHGRI_mPanPan11835,742,809 - 35,844,315 (-)NCBI
Mhudiblu_PPA_v01825,880,582 - 26,003,452 (-)NCBI
RefSeq Acc Id: XM_055102588   ⟹   XP_054958563
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21750,050,211 - 50,150,404 (-)NCBI
NHGRI_mPanPan11835,742,809 - 35,842,974 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034799826 (Get FASTA)   NCBI Sequence Viewer  
  XP_054958563 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038938.1
Reference Protein Sequences
RefSeq Acc Id: XP_034799826   ⟸   XM_034943935
- UniProtKB: A0A2R9CD63 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000038938   ⟸   ENSPPAT00000061847
RefSeq Acc Id: XP_054958563   ⟸   XM_055102588
- UniProtKB: A0A2R9CD63 (UniProtKB/TrEMBL)
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042187 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061847.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  KLHL14 UniProtKB/TrEMBL
  KLHL14_BACK UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
NCBI Gene KLHL14 ENTREZGENE
PANTHER LD33804P UniProtKB/TrEMBL
  PTHR45632:SF6 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A2R9CD63 ENTREZGENE, UniProtKB/TrEMBL