Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Il20rb | Rat | 1,2-dichloroethane | increases expression | ISO | Il20rb (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of IL20RB mRNA | CTD | PMID:28960355 | Il20rb | Rat | 17beta-estradiol | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of IL20RB mRNA | CTD | PMID:30165855 | Il20rb | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Il20rb (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of IL20RB mRNA | CTD | PMID:21570461 | Il20rb | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | 2,2',4,4',5-brominated diphenyl ether results in increased expression of IL20RB mRNA | CTD | PMID:26705709 | Il20rb | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of IL20RB mRNA | CTD | PMID:30851411 | Il20rb | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | IL20RB (Homo sapiens) | 6480464 | Decitabine affects the expression of IL20RB mRNA | CTD | PMID:23300844 | Il20rb | Rat | acrolein | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Il20rb | Rat | acrylamide | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Acrylamide results in increased expression of IL20RB mRNA | CTD | PMID:32763439 | Il20rb | Rat | alpha-pinene | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Il20rb | Rat | alpha-Zearalanol | decreases expression | EXP | | 6480464 | Zeranol results in decreased expression of IL20RB mRNA | CTD | PMID:35163327 | Il20rb | Rat | antirheumatic drug | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of IL20RB mRNA | CTD | PMID:24449571 | Il20rb | Rat | aristolochic acid A | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of IL20RB mRNA | CTD | PMID:33212167 | Il20rb | Rat | arsenous acid | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of IL20RB mRNA | CTD | PMID:26705709 | Il20rb | Rat | Azoxymethane | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL20RB more ... | CTD | PMID:29950665 | Il20rb | Rat | belinostat | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | belinostat results in increased expression of IL20RB mRNA | CTD | PMID:26272509 | Il20rb | Rat | belinostat | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Il20rb | Rat | benzo[a]pyrene | decreases methylation | ISO | IL20RB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of IL20RB exon; Benzo(a)pyrene results in decreased methylation of IL20RB more ... | CTD | PMID:27901495 | Il20rb | Rat | beta-lapachone | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of IL20RB mRNA | CTD | PMID:38218311 | Il20rb | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | Asian ginseng inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of IL20RB mRNA] | CTD | PMID:35818422 | Il20rb | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of IL20RB mRNA | CTD | PMID:35818422 | Il20rb | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of IL20RB mRNA | CTD | PMID:25181051 | Il20rb | Rat | bisphenol A | increases expression | ISO | Il20rb (Mus musculus) | 6480464 | bisphenol A results in increased expression of IL20RB mRNA | CTD | PMID:32156529 | Il20rb | Rat | Butylbenzyl phthalate | increases methylation | ISO | Il20rb (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of IL20RB 3' UTR | CTD | PMID:28392331 | Il20rb | Rat | butyric acid | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Butyric Acid results in decreased expression of IL20RB mRNA | CTD | PMID:34581912 | Il20rb | Rat | cadmium dichloride | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of IL20RB mRNA | CTD | PMID:38382870 | Il20rb | Rat | cadmium dichloride | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of IL20RB mRNA | CTD | PMID:38568856 | Il20rb | Rat | CGP 52608 | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to IL20RB gene] | CTD | PMID:28238834 | Il20rb | Rat | chloropicrin | affects expression | ISO | IL20RB (Homo sapiens) | 6480464 | chloropicrin affects the expression of IL20RB mRNA | CTD | PMID:26352163 | Il20rb | Rat | choline | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Il20rb | Rat | cisplatin | affects expression | ISO | IL20RB (Homo sapiens) | 6480464 | Cisplatin affects the expression of IL20RB mRNA | CTD | PMID:23300844 | Il20rb | Rat | cisplatin | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Cisplatin results in increased expression of IL20RB mRNA | CTD | PMID:27392435 | Il20rb | Rat | copper atom | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of IL20RB mRNA | CTD | PMID:20971185 | Il20rb | Rat | copper(0) | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of IL20RB mRNA | CTD | PMID:20971185 | Il20rb | Rat | copper(II) chloride | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | cupric chloride results in decreased expression of IL20RB mRNA | CTD | PMID:38568856 | Il20rb | Rat | copper(II) sulfate | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of IL20RB mRNA | CTD | PMID:19549813 | Il20rb | Rat | cyclosporin A | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of IL20RB mRNA | CTD | PMID:20106945|PMID:27989131 | Il20rb | Rat | dexamethasone | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Dexamethasone results in decreased expression of IL20RB mRNA | CTD | PMID:25047013 | Il20rb | Rat | dextran sulfate | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL20RB more ... | CTD | PMID:29950665 | Il20rb | Rat | diarsenic trioxide | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of IL20RB mRNA | CTD | PMID:26705709 | Il20rb | Rat | dichloroacetic acid | increases expression | ISO | Il20rb (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of IL20RB mRNA | CTD | PMID:28962523 | Il20rb | Rat | dimethylarsinic acid | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Il20rb | Rat | dorsomorphin | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Il20rb | Rat | entinostat | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | entinostat results in increased expression of IL20RB mRNA | CTD | PMID:26272509|PMID:27188386 | Il20rb | Rat | entinostat | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Il20rb | Rat | ferulic acid | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL20RB mRNA] | CTD | PMID:31054998 | Il20rb | Rat | folic acid | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Il20rb | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of IL20RB mRNA | CTD | PMID:33387578 | Il20rb | Rat | hydrogen peroxide | affects expression | ISO | IL20RB (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of IL20RB mRNA | CTD | PMID:20044591 | Il20rb | Rat | imiquimod | increases expression | ISO | Il20rb (Mus musculus) | 6480464 | Imiquimod results in increased expression of IL20RB mRNA | CTD | PMID:31054998 | Il20rb | Rat | imiquimod | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL20RB mRNA] | CTD | PMID:31054998 | Il20rb | Rat | L-methionine | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Il20rb | Rat | mercury dichloride | increases expression | EXP | | 6480464 | Mercuric Chloride results in increased expression of IL20RB mRNA | CTD | PMID:18496552 | Il20rb | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of IL20RB gene | CTD | PMID:35440735 | Il20rb | Rat | methylarsonic acid | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Il20rb | Rat | microcystin-LR | increases expression | ISO | Il20rb (Mus musculus) | 6480464 | cyanoginosin LR results in increased expression of IL20RB mRNA | CTD | PMID:37342990 | Il20rb | Rat | okadaic acid | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of IL20RB mRNA | CTD | PMID:38832940 | Il20rb | Rat | ozone | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Il20rb | Rat | palbociclib | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | palbociclib results in increased expression of IL20RB mRNA | CTD | PMID:22869556 | Il20rb | Rat | panobinostat | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | panobinostat results in increased expression of IL20RB mRNA | CTD | PMID:26272509 | Il20rb | Rat | panobinostat | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Il20rb | Rat | paracetamol | affects expression | ISO | Il20rb (Mus musculus) | 6480464 | Acetaminophen affects the expression of IL20RB mRNA | CTD | PMID:17562736 | Il20rb | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of IL20RB mRNA | CTD | PMID:33387578 | Il20rb | Rat | perfluorononanoic acid | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of IL20RB mRNA | CTD | PMID:32588087 | Il20rb | Rat | propanal | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of IL20RB mRNA | CTD | PMID:26079696 | Il20rb | Rat | Ptaquiloside | decreases expression | ISO | Il20rb (Mus musculus) | 6480464 | ptaquiloside results in decreased expression of IL20RB mRNA | CTD | PMID:23274088 | Il20rb | Rat | quercetin | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Quercetin results in increased expression of IL20RB mRNA | CTD | PMID:21632981 | Il20rb | Rat | rac-lactic acid | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of IL20RB mRNA | CTD | PMID:30851411 | Il20rb | Rat | S-nitrosoglutathione | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | S-Nitrosoglutathione results in increased expression of IL20RB mRNA | CTD | PMID:38825487 | Il20rb | Rat | SB 431542 | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Il20rb | Rat | silver atom | decreases expression | ISO | Il20rb (Mus musculus) | 6480464 | Silver results in decreased expression of IL20RB mRNA | CTD | PMID:27131904 | Il20rb | Rat | silver(0) | decreases expression | ISO | Il20rb (Mus musculus) | 6480464 | Silver results in decreased expression of IL20RB mRNA | CTD | PMID:27131904 | Il20rb | Rat | simvastatin | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Simvastatin results in increased expression of IL20RB mRNA | CTD | PMID:17428261 | Il20rb | Rat | sodium arsenate | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Il20rb | Rat | sodium arsenite | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of IL20RB mRNA | CTD | PMID:28595984|PMID:34032870 | Il20rb | Rat | sodium arsenite | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Il20rb | Rat | sodium arsenite | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of IL20RB mRNA | CTD | PMID:29301061|PMID:38568856|PMID:39719251 | Il20rb | Rat | T-2 toxin | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | T-2 Toxin results in decreased expression of IL20RB mRNA | CTD | PMID:34581912 | Il20rb | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of IL20RB mRNA | CTD | PMID:34492290 | Il20rb | Rat | thiram | decreases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Thiram results in decreased expression of IL20RB mRNA | CTD | PMID:38568856 | Il20rb | Rat | titanium dioxide | increases expression | ISO | Il20rb (Mus musculus) | 6480464 | titanium dioxide results in increased expression of IL20RB mRNA | CTD | PMID:27760801 | Il20rb | Rat | titanium dioxide | multiple interactions | ISO | Il20rb (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL20RB more ... | CTD | PMID:29950665 | Il20rb | Rat | trichostatin A | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | trichostatin A results in increased expression of IL20RB mRNA | CTD | PMID:24935251 | Il20rb | Rat | urethane | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Urethane results in increased expression of IL20RB mRNA | CTD | PMID:28818685 | Il20rb | Rat | valproic acid | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of IL20RB mRNA | CTD | PMID:24935251 | Il20rb | Rat | valproic acid | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Il20rb | Rat | vorinostat | multiple interactions | ISO | IL20RB (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Il20rb | Rat | vorinostat | increases expression | ISO | IL20RB (Homo sapiens) | 6480464 | vorinostat results in increased expression of IL20RB mRNA | CTD | PMID:26272509 | | 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