Nutm2 (NUT family member 2) - Rat Genome Database

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Gene: Nutm2 (NUT family member 2) Rattus norvegicus
Analyze
Symbol: Nutm2
Name: NUT family member 2
RGD ID: 1566043
Description: Orthologous to several human genes including NUTM2B (NUT family member 2B); INTERACTS WITH bis(2-ethylhexyl) phthalate (ortholog); bisphenol A (ortholog); cisplatin (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fam22f; family with sequence similarity 22, member F; LOC306798; NUT family member 2F; Nutm2f; RGD1566043; similar to family with sequence similarity 22, member F
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81714,575,374 - 14,583,146 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1714,575,357 - 14,583,144 (+)EnsemblGRCr8
mRatBN7.21714,423,714 - 14,431,486 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1714,423,735 - 14,431,397 (+)EnsemblmRatBN7.2
Rnor_6.01715,022,052 - 15,031,768 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1715,022,951 - 15,030,364 (-)Ensemblrn6Rnor6.0
Rnor_5.01717,080,448 - 17,088,182 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41720,332,714 - 20,340,129 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1714,157,968 - 14,167,672 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Nutm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81714,575,374 - 14,583,146 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1714,575,357 - 14,583,144 (+)EnsemblGRCr8
mRatBN7.21714,423,714 - 14,431,486 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1714,423,735 - 14,431,397 (+)EnsemblmRatBN7.2
Rnor_6.01715,022,052 - 15,031,768 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1715,022,951 - 15,030,364 (-)Ensemblrn6Rnor6.0
Rnor_5.01717,080,448 - 17,088,182 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41720,332,714 - 20,340,129 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1714,157,968 - 14,167,672 (+)NCBICelera
Cytogenetic Map17p14NCBI
NUTM2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381087,225,448 - 87,234,978 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1087,225,448 - 87,236,908 (+)Ensemblhg38GRCh38
GRCh371088,985,205 - 88,994,735 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361088,975,185 - 88,984,715 (+)NCBIBuild 36Build 36hg18NCBI36
Cytogenetic Map10q23.2NCBI
CHM1_11089,266,969 - 89,276,525 (+)NCBICHM1_1
T2T-CHM13v2.01088,109,085 - 88,118,613 (+)NCBIT2T-CHM13v2.0
Nutm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391350,621,343 - 50,629,391 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1350,621,343 - 50,629,391 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381350,467,307 - 50,475,355 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1350,467,307 - 50,475,355 (+)Ensemblmm10GRCm38
MGSCv371350,562,676 - 50,570,724 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361350,479,804 - 50,487,852 (+)NCBIMGSCv36mm8
Celera1351,554,147 - 51,562,195 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1325.75NCBI

Variants

.
Variants in Nutm2
170 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000044543
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17926675540968173Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
8552966Pigfal18Plasma insulin-like growth factor 1 level QTL 188.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)171286094257860942Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920650523859062Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
9589151Insul30Insulin level QTL 308.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)171286094257860942Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
9589057Scfw6Subcutaneous fat weight QTL 68.620.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)171286094257860942Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920650523859062Rat
9590154Scort9Serum corticosterone level QTL 923.570.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)171286094257860942Rat
9590088Insglur7Insulin/glucose ratio QTL 720.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)171286094257860942Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)171060469455604694Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
7411666Foco31Food consumption QTL 3111.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)171286094257860942Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
1581553Pur14Proteinuria QTL 145.30.0001urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)17798524316523460Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17857434232199534Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920650523859062Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
G47094  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21714,429,617 - 14,429,854 (-)MAPPERmRatBN7.2
Rnor_6.01715,024,316 - 15,024,552NCBIRnor6.0
Rnor_5.01717,082,072 - 17,082,308UniSTSRnor5.0
RGSC_v3.41720,338,526 - 20,338,762UniSTSRGSC3.4
Celera1714,165,184 - 14,165,408UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
2 1 13 12 7 7 2 24 10 9 12 33 7 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000044543   ⟹   ENSRNOP00000042166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1714,575,357 - 14,583,144 (+)Ensembl
mRatBN7.2 Ensembl1714,423,735 - 14,431,397 (+)Ensembl
Rnor_6.0 Ensembl1715,022,951 - 15,030,364 (-)Ensembl
RefSeq Acc Id: NM_001419755   ⟹   NP_001406684
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81714,575,374 - 14,583,146 (+)NCBI
mRatBN7.21714,423,714 - 14,431,486 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001406684 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98100 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000042166
  ENSRNOP00000042166.2
Ensembl Acc Id: ENSRNOP00000042166   ⟸   ENSRNOT00000044543
RefSeq Acc Id: NP_001406684   ⟸   NM_001419755
- UniProtKB: D4A4R3 (UniProtKB/TrEMBL)
Protein Domains
Nuclear Testis protein N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4R3-F1-model_v2 AlphaFold D4A4R3 1-735 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566043 AgrOrtholog
BioCyc Gene G2FUF-10039 BioCyc
Ensembl Genes ENSRNOG00000027311 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044543 ENTREZGENE
  ENSRNOT00000044543.5 UniProtKB/TrEMBL
InterPro NUT/FAM22 UniProtKB/TrEMBL
  NUT_N UniProtKB/TrEMBL
NCBI Gene 306798 ENTREZGENE
PANTHER NUT FAMILY MEMBER 2A-RELATED UniProtKB/TrEMBL
  PTHR22879 UniProtKB/TrEMBL
Pfam NUT_N UniProtKB/TrEMBL
PhenoGen Nutm2 PhenoGen
RatGTEx ENSRNOG00000027311 RatGTEx
UniProt D4A4R3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-05-14 Nutm2  NUT family member 2  Nutm2f  NUT family member 2F  Name and Symbol changed 629549 APPROVED
2013-08-01 Nutm2f  NUT family member 2F  Fam22f  family with sequence similarity 22, member F  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 Fam22f  family with sequence similarity 22, member F  RGD1566043  similar to family with sequence similarity 22, member F  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1566043  similar to family with sequence similarity 22, member F   RGD1566043_predicted  similar to family with sequence similarity 22, member F (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1566043_predicted  similar to family with sequence similarity 22, member F (predicted)  LOC306798  similar to family with sequence similarity 22, member F  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC306798  similar to family with sequence similarity 22, member F      Symbol and Name status set to provisional 70820 PROVISIONAL