Nol7 (nucleolar protein 7) - Rat Genome Database

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Gene: Nol7 (nucleolar protein 7) Rattus norvegicus
Analyze
Symbol: Nol7
Name: nucleolar protein 7
RGD ID: 1565934
Description: Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in chromosome; mitochondrion; and nucleus. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human NOL7 (nucleolar protein 7); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC498727; Nol7-ps1; nucleolar protein 7, pseudogene 1; RGD1565934; similar to nucleolar protein 7, 27kDa
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81721,509,605 - 21,512,879 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1721,509,605 - 21,513,196 (-)EnsemblGRCr8
mRatBN7.21721,303,650 - 21,306,924 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1721,302,624 - 21,307,431 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1721,192,465 - 21,195,737 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01722,796,134 - 22,799,406 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01721,119,568 - 21,122,840 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01724,016,939 - 24,020,231 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1724,015,982 - 24,020,261 (+)Ensemblrn6Rnor6.0
Rnor_5.01725,966,367 - 25,969,809 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41727,127,979 - 27,132,484 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1721,001,063 - 21,004,415 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IBA,IEA,ISO)
nucleus  (IEA)
small-subunit processome  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22658674  


Genomics

Comparative Map Data
Nol7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81721,509,605 - 21,512,879 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1721,509,605 - 21,513,196 (-)EnsemblGRCr8
mRatBN7.21721,303,650 - 21,306,924 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1721,302,624 - 21,307,431 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1721,192,465 - 21,195,737 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01722,796,134 - 22,799,406 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01721,119,568 - 21,122,840 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01724,016,939 - 24,020,231 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1724,015,982 - 24,020,261 (+)Ensemblrn6Rnor6.0
Rnor_5.01725,966,367 - 25,969,809 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41727,127,979 - 27,132,484 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1721,001,063 - 21,004,415 (-)NCBICelera
Cytogenetic Map17p14NCBI
NOL7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38613,615,335 - 13,632,470 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl613,615,335 - 13,633,912 (+)Ensemblhg38GRCh38
GRCh37613,615,567 - 13,632,702 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36613,723,538 - 13,729,106 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34613,723,537 - 13,729,105NCBI
Celera614,855,054 - 14,860,622 (+)NCBICelera
Cytogenetic Map6p23NCBI
HuRef613,559,935 - 13,565,503 (+)NCBIHuRef
CHM1_1613,617,926 - 13,623,494 (+)NCBICHM1_1
T2T-CHM13v2.0613,488,892 - 13,506,009 (+)NCBIT2T-CHM13v2.0
Nol7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391343,551,852 - 43,556,334 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1343,551,866 - 43,560,573 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381343,398,376 - 43,402,858 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1343,398,390 - 43,407,097 (+)Ensemblmm10GRCm38
MGSCv371343,493,745 - 43,498,227 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361343,409,365 - 43,413,835 (+)NCBIMGSCv36mm8
Celera1344,476,966 - 44,481,446 (+)NCBICelera
Cytogenetic Map13A4NCBI
cM Map1321.6NCBI
Nol7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554651,123,518 - 1,127,433 (-)Ensembl
ChiLan1.0NW_0049554651,123,455 - 1,127,529 (-)NCBIChiLan1.0ChiLan1.0
NOL7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2528,265,810 - 28,274,470 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1624,259,266 - 24,265,288 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0613,460,225 - 13,466,230 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1613,828,474 - 13,837,472 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl613,831,493 - 13,836,712 (+)EnsemblpanPan2panpan1.1
NOL7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13513,058,894 - 13,063,367 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3513,017,397 - 13,063,022 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3513,008,242 - 13,012,362 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03513,157,389 - 13,161,539 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3513,115,780 - 13,179,805 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13512,982,835 - 12,986,958 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03513,034,346 - 13,038,501 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03514,359,355 - 14,363,470 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nol7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494611,509,818 - 11,514,513 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936552217,340 - 222,420 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936552217,197 - 221,118 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOL7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl79,971,209 - 9,983,827 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.179,969,483 - 9,978,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NOL7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11758,528,431 - 58,532,563 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1758,528,500 - 58,532,533 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604413,665,438 - 13,679,174 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nol7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475612,673,398 - 12,677,173 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475612,673,328 - 12,677,223 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Nol7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11462,405,886 - 62,409,253 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nol7
22 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:13
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000024122
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17926675540968173Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
8552966Pigfal18Plasma insulin-like growth factor 1 level QTL 188.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)171286094257860942Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920650523859062Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
9589151Insul30Insulin level QTL 308.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)171286094257860942Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172149899450592236Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
9589057Scfw6Subcutaneous fat weight QTL 68.620.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)171286094257860942Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920650523859062Rat
9590154Scort9Serum corticosterone level QTL 923.570.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)171286094257860942Rat
9590088Insglur7Insulin/glucose ratio QTL 720.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)171286094257860942Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
1331720Rf43Renal function QTL 432.881kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)171553702528637951Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)171060469455604694Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171553702560531414Rat
7411666Foco31Food consumption QTL 3111.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)171286094257860942Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17857434232199534Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920650523859062Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
RH133329  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81721,510,034 - 21,510,295 (+)Marker Load Pipeline
mRatBN7.21721,304,079 - 21,304,340 (-)MAPPERmRatBN7.2
Rnor_6.01724,019,539 - 24,019,800NCBIRnor6.0
Rnor_5.01725,969,119 - 25,969,380UniSTSRnor5.0
Celera1721,001,506 - 21,001,766UniSTS
RH 3.4 Map17267.9UniSTS
Cytogenetic Map17p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000024122   ⟹   ENSRNOP00000024122
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1721,509,605 - 21,513,196 (-)Ensembl
mRatBN7.2 Ensembl1721,302,624 - 21,307,431 (-)Ensembl
Rnor_6.0 Ensembl1724,015,982 - 24,020,261 (+)Ensembl
RefSeq Acc Id: NM_001400771   ⟹   NP_001387700
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81721,509,605 - 21,512,879 (-)NCBI
mRatBN7.21721,303,650 - 21,306,924 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001387700 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98196 (Get FASTA)   NCBI Sequence Viewer  
  EDL98197 (Get FASTA)   NCBI Sequence Viewer  
  EDL98198 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024122
  ENSRNOP00000024122.6
Ensembl Acc Id: ENSRNOP00000024122   ⟸   ENSRNOT00000024122
RefSeq Acc Id: NP_001387700   ⟸   NM_001400771
- UniProtKB: A6J746 (UniProtKB/TrEMBL),   D3ZAQ6 (UniProtKB/TrEMBL)
Protein Domains
U3 small nucleolar RNA-associated protein NOL7 C-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAQ6-F1-model_v2 AlphaFold D3ZAQ6 1-297 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565934 AgrOrtholog
BioCyc Gene G2FUF-9800 BioCyc
Ensembl Genes ENSRNOG00000017904 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024122 ENTREZGENE
  ENSRNOT00000024122.8 UniProtKB/TrEMBL
InterPro NUC129 UniProtKB/TrEMBL
NCBI Gene 498727 ENTREZGENE
PANTHER NUCLEOLAR PROTEIN 7 UniProtKB/TrEMBL
  PTHR32337 UniProtKB/TrEMBL
Pfam NUC129 UniProtKB/TrEMBL
PhenoGen Nol7 PhenoGen
RatGTEx ENSRNOG00000017904 RatGTEx
UniProt A6J746 ENTREZGENE, UniProtKB/TrEMBL
  D3ZAQ6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-05 Nol7  nucleolar protein 7  Nol7-ps1  nucleolar protein 7, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-06-08 Nol7-ps1  nucleolar protein 7, pseudogene 1  Nol7  nucleolar protein 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Nol7  nucleolar protein 7  RGD1565934_predicted  similar to nucleolar protein 7, 27kDa (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1565934_predicted  similar to nucleolar protein 7, 27kDa (predicted)  LOC498727  similar to nucleolar protein 7, 27kDa  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498727  similar to nucleolar protein 7, 27kDa      Symbol and Name status set to provisional 70820 PROVISIONAL