Ly6e (lymphocyte antigen 6 family member E) - Rat Genome Database

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Gene: Ly6e (lymphocyte antigen 6 family member E) Rattus norvegicus
Analyze
Symbol: Ly6e
Name: lymphocyte antigen 6 family member E
RGD ID: 1565342
Description: Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway and negative regulation of viral entry into host cell. Predicted to act upstream of or within several processes, including adrenal gland development; epinephrine secretion; and ventricular cardiac muscle tissue morphogenesis. Predicted to be located in synapse. Predicted to be active in plasma membrane. Orthologous to human LY6E (lymphocyte antigen 6 family member E); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362934; lymphocyte antigen 6 complex, locus E; lymphocyte antigen 6E; similar to lymphocyte antigen 6 complex, locus E
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87108,815,970 - 108,820,444 (+)NCBIGRCr8
mRatBN7.27106,935,530 - 106,939,689 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7106,935,761 - 106,939,689 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7108,669,406 - 108,673,107 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07110,893,074 - 110,896,775 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07110,839,029 - 110,842,730 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07116,355,426 - 116,359,862 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,355,698 - 116,359,862 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,253,329 - 116,257,488 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,151,828 - 113,155,521 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7103,308,659 - 103,312,352 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-bromohexadecanoic acid  (ISO)
2-butoxyethanol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aconitine  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
arsenous acid  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cholesterol  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
diuron  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
etoposide  (ISO)
fumonisin B1  (ISO)
genistein  (ISO)
gentamycin  (EXP)
hydroquinone  (ISO)
inulin  (ISO)
lipopolysaccharide  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mifepristone  (ISO)
N-nitrosodiethylamine  (ISO)
nimesulide  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
selenium atom  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tamoxifen  (EXP,ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiophenes  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
Triptolide  (EXP)
triptonide  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
plasma membrane  (IBA)
synapse  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11784869   PMID:26276394  


Genomics

Comparative Map Data
Ly6e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87108,815,970 - 108,820,444 (+)NCBIGRCr8
mRatBN7.27106,935,530 - 106,939,689 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7106,935,761 - 106,939,689 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7108,669,406 - 108,673,107 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07110,893,074 - 110,896,775 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07110,839,029 - 110,842,730 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07116,355,426 - 116,359,862 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,355,698 - 116,359,862 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,253,329 - 116,257,488 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,151,828 - 113,155,521 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7103,308,659 - 103,312,352 (+)NCBICelera
Cytogenetic Map7q34NCBI
LY6E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,018,529 - 143,022,409 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8143,017,982 - 143,023,832 (+)EnsemblGRCh38hg38GRCh38
GRCh378144,099,946 - 144,103,826 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,171,300 - 144,175,199 (+)NCBINCBI36Build 36hg18NCBI36
Build 348144,171,299 - 144,175,199NCBI
Celera8140,409,515 - 140,413,440 (+)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,353,438 - 139,357,363 (+)NCBIHuRef
CHM1_18144,140,603 - 144,144,526 (+)NCBICHM1_1
T2T-CHM13v2.08144,162,226 - 144,166,106 (+)NCBIT2T-CHM13v2.0
Ly6e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391574,826,874 - 74,831,753 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1574,826,900 - 74,831,752 (+)EnsemblGRCm39 Ensembl
GRCm381574,955,025 - 74,959,904 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1574,955,051 - 74,959,905 (+)EnsemblGRCm38mm10GRCm38
MGSCv371574,785,481 - 74,790,335 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361574,782,911 - 74,786,586 (+)NCBIMGSCv36mm8
Celera1576,460,639 - 76,465,493 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.29NCBI
LY6E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27160,476,856 - 160,481,322 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18135,991,649 - 135,996,048 (+)NCBINHGRI_mPanPan1
LY6E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11336,926,776 - 36,930,265 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1336,925,980 - 36,974,979 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1336,879,527 - 36,883,015 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,398,524 - 37,402,004 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,397,547 - 37,402,001 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,071,189 - 37,074,676 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,189,559 - 37,193,039 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,666,368 - 37,669,857 (+)NCBIUU_Cfam_GSD_1.0
Ly6e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,453,118 - 1,455,165 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364708,879,217 - 8,880,777 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LY6E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl41,337,196 - 1,340,786 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.141,336,112 - 1,341,112 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LY6E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,265,510 - 137,269,397 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,265,535 - 137,269,404 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660392,674,673 - 2,678,569 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ly6e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473513,616,129 - 13,619,538 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ly6e
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:263
Count of miRNA genes:153
Interacting mature miRNAs:169
Transcripts:ENSRNOT00000009333
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000009333   ⟹   ENSRNOP00000009333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7106,935,996 - 106,939,689 (+)Ensembl
Rnor_6.0 Ensembl7116,356,169 - 116,359,862 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075873   ⟹   ENSRNOP00000068045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,356,330 - 116,359,164 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076182   ⟹   ENSRNOP00000068333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,355,911 - 116,359,265 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076279   ⟹   ENSRNOP00000068066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,357,783 - 116,359,330 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,356,278 - 116,357,160 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076407   ⟹   ENSRNOP00000068134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,356,324 - 116,358,878 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076412   ⟹   ENSRNOP00000068317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,356,163 - 116,359,286 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076693   ⟹   ENSRNOP00000068163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,355,698 - 116,359,314 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076790   ⟹   ENSRNOP00000068244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7106,935,761 - 106,939,689 (+)Ensembl
Rnor_6.0 Ensembl7116,357,175 - 116,359,862 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077022   ⟹   ENSRNOP00000068165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7116,356,329 - 116,359,141 (+)Ensembl
RefSeq Acc Id: NM_001017467   ⟹   NP_001017467
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87108,816,751 - 108,820,444 (+)NCBI
mRatBN7.27106,935,996 - 106,939,689 (+)NCBI
Rnor_6.07116,356,169 - 116,359,862 (+)NCBI
Rnor_5.07116,253,329 - 116,257,488 (+)NCBI
RGSC_v3.47113,151,828 - 113,155,521 (+)RGD
Celera7103,308,659 - 103,312,352 (+)RGD
Sequence:
RefSeq Acc Id: XM_006241757   ⟹   XP_006241819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87108,816,498 - 108,820,444 (+)NCBI
mRatBN7.27106,935,911 - 106,939,689 (+)NCBI
Rnor_6.07116,356,023 - 116,359,862 (+)NCBI
Rnor_5.07116,253,329 - 116,257,488 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241759   ⟹   XP_006241821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87108,816,911 - 108,820,444 (+)NCBI
mRatBN7.27106,935,894 - 106,939,689 (+)NCBI
Rnor_6.07116,356,018 - 116,359,862 (+)NCBI
Rnor_5.07116,253,329 - 116,257,488 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241762   ⟹   XP_006241824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87108,815,970 - 108,820,444 (+)NCBI
mRatBN7.27106,935,801 - 106,939,689 (+)NCBI
Rnor_6.07116,355,426 - 116,359,862 (+)NCBI
Rnor_5.07116,253,329 - 116,257,488 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001017467   ⟸   NM_001017467
- Peptide Label: precursor
- UniProtKB: Q6AY73 (UniProtKB/TrEMBL),   A6HS00 (UniProtKB/TrEMBL),   A6HRZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241824   ⟸   XM_006241762
- Peptide Label: isoform X2
- UniProtKB: Q6AY73 (UniProtKB/TrEMBL),   A6HS00 (UniProtKB/TrEMBL),   A6HRZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241819   ⟸   XM_006241757
- Peptide Label: isoform X1
- UniProtKB: A0A096MJS6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241821   ⟸   XM_006241759
- Peptide Label: isoform X2
- UniProtKB: Q6AY73 (UniProtKB/TrEMBL),   A6HS00 (UniProtKB/TrEMBL),   A6HRZ9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068165   ⟸   ENSRNOT00000077022
Ensembl Acc Id: ENSRNOP00000068045   ⟸   ENSRNOT00000075873
Ensembl Acc Id: ENSRNOP00000009333   ⟸   ENSRNOT00000009333
Ensembl Acc Id: ENSRNOP00000068066   ⟸   ENSRNOT00000076279
Ensembl Acc Id: ENSRNOP00000068333   ⟸   ENSRNOT00000076182
Ensembl Acc Id: ENSRNOP00000068163   ⟸   ENSRNOT00000076693
Ensembl Acc Id: ENSRNOP00000068244   ⟸   ENSRNOT00000076790
Ensembl Acc Id: ENSRNOP00000068317   ⟸   ENSRNOT00000076412
Ensembl Acc Id: ENSRNOP00000068134   ⟸   ENSRNOT00000076407
Protein Domains
UPAR/Ly6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY73-F1-model_v2 AlphaFold Q6AY73 1-136 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695383
Promoter ID:EPDNEW_R5906
Type:multiple initiation site
Name:Ly6e_2
Description:lymphocyte antigen 6 family member E
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5907  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07116,355,911 - 116,355,971EPDNEW
RGD ID:13695384
Promoter ID:EPDNEW_R5907
Type:initiation region
Name:Ly6e_1
Description:lymphocyte antigen 6 family member E
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5906  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07116,356,278 - 116,356,338EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565342 AgrOrtholog
BioCyc Gene G2FUF-33003 BioCyc
Ensembl Genes ENSRNOG00000007091 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009333.7 UniProtKB/TrEMBL
  ENSRNOT00000076790.3 UniProtKB/TrEMBL
Gene3D-CATH 2.10.60.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7129625 IMAGE-MGC_LOAD
InterPro Ly-6/neurotoxin-like_GPI-ap UniProtKB/TrEMBL
  LY6_UPA_recep-like UniProtKB/TrEMBL
  Snake_toxin-like_sf UniProtKB/TrEMBL
KEGG Report rno:362934 UniProtKB/TrEMBL
MGC_CLONE MGC:94196 IMAGE-MGC_LOAD
NCBI Gene 362934 ENTREZGENE
PANTHER LYMPHOCYTE ANTIGEN 6E UniProtKB/TrEMBL
  UPAR/LY6 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam UPAR_LY6 UniProtKB/TrEMBL
PhenoGen Ly6e PhenoGen
RatGTEx ENSRNOG00000007091 RatGTEx
SMART SM00134 UniProtKB/TrEMBL
Superfamily-SCOP SSF57302 UniProtKB/TrEMBL
UniProt A0A096MJS6 ENTREZGENE, UniProtKB/TrEMBL
  A6HRZ9 ENTREZGENE, UniProtKB/TrEMBL
  A6HS00 ENTREZGENE, UniProtKB/TrEMBL
  Q6AY73 ENTREZGENE
UniProt Secondary Q6AY73 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-01 Ly6e  lymphocyte antigen 6 family member E  Ly6e  lymphocyte antigen 6 complex, locus E  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Ly6e  lymphocyte antigen 6 complex, locus E  LOC362934  similar to lymphocyte antigen 6 complex, locus E  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC362934  similar to lymphocyte antigen 6 complex, locus E      Symbol and Name status set to provisional 70820 PROVISIONAL