Rufy3 (RUN and FYVE domain containing 3) - Rat Genome Database

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Gene: Rufy3 (RUN and FYVE domain containing 3) Rattus norvegicus
Analyze
Symbol: Rufy3
Name: RUN and FYVE domain containing 3
RGD ID: 1565242
Description: Predicted to enable metal ion binding activity. Involved in negative regulation of axonogenesis. Located in several cellular components, including growth cone; lamellipodium; and perikaryon. Orthologous to human RUFY3 (RUN and FYVE domain containing 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: rap2 interacting protein x; rap2-interacting protein x; Ripx; RUN and FYVE domain-containing protein 3; singar; Singar1; singar2; single axon-regulated protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81419,715,593 - 19,790,530 (-)NCBIGRCr8
mRatBN7.21419,431,530 - 19,506,476 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1419,432,524 - 19,507,004 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1419,420,898 - 19,495,871 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01420,739,762 - 20,814,733 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01419,442,194 - 19,517,510 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01421,058,575 - 21,144,775 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1421,058,595 - 21,128,505 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01420,968,402 - 21,040,629 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41421,022,765 - 21,070,152 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1418,782,702 - 18,829,205 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
anchoring junction  (IEA)
axon  (IBA,IEA,ISS)
cytoplasm  (IBA,IEA,ISO,ISS)
cytosol  (IEA,ISO)
dendrite  (IBA,IDA,IEA,ISS)
endomembrane system  (IEA)
filopodium  (IDA)
growth cone  (IDA,ISO)
lamellipodium  (IDA)
membrane  (IEA)
neuronal cell body  (IBA,IEA)
perikaryon  (IDA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Singar1, a novel RUN domain-containing protein, suppresses formation of surplus axons for neuronal polarity. Mori T, etal., J Biol Chem. 2007 Jul 6;282(27):19884-93. Epub 2007 Apr 17.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:22871113   PMID:23206279   PMID:23904609   PMID:24720729   PMID:25766321  


Genomics

Comparative Map Data
Rufy3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81419,715,593 - 19,790,530 (-)NCBIGRCr8
mRatBN7.21419,431,530 - 19,506,476 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1419,432,524 - 19,507,004 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1419,420,898 - 19,495,871 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01420,739,762 - 20,814,733 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01419,442,194 - 19,517,510 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01421,058,575 - 21,144,775 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1421,058,595 - 21,128,505 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01420,968,402 - 21,040,629 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41421,022,765 - 21,070,152 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1418,782,702 - 18,829,205 (-)NCBICelera
Cytogenetic Map14p22NCBI
RUFY3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38470,703,767 - 70,808,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl470,704,204 - 70,808,619 (+)EnsemblGRCh38hg38GRCh38
GRCh37471,570,456 - 71,674,336 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36471,806,560 - 71,891,789 (+)NCBINCBI36Build 36hg18NCBI36
Celera468,927,653 - 69,031,337 (+)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef467,374,309 - 67,478,077 (+)NCBIHuRef
CHM1_1471,606,608 - 71,710,363 (+)NCBICHM1_1
T2T-CHM13v2.0474,046,233 - 74,151,087 (+)NCBIT2T-CHM13v2.0
Rufy3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39588,711,305 - 88,799,276 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl588,712,899 - 88,799,251 (+)EnsemblGRCm39 Ensembl
GRCm38588,564,505 - 88,651,417 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl588,565,040 - 88,651,392 (+)EnsemblGRCm38mm10GRCm38
MGSCv37589,012,599 - 89,071,721 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36589,658,135 - 89,717,257 (+)NCBIMGSCv36mm8
Celera586,733,200 - 86,791,895 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.77NCBI
Rufy3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554472,211,262 - 2,266,008 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554472,200,788 - 2,266,008 (-)NCBIChiLan1.0ChiLan1.0
RUFY3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2359,276,447 - 59,377,256 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1459,471,389 - 59,572,248 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0453,415,742 - 53,516,600 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1459,762,339 - 59,846,574 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl459,762,053 - 59,846,574 (-)Ensemblpanpan1.1panPan2
RUFY3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11360,007,041 - 60,079,198 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1360,007,056 - 60,078,617 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1359,741,413 - 59,813,528 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01360,813,185 - 60,885,065 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1360,812,369 - 60,885,059 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11360,427,868 - 60,499,800 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01359,919,548 - 59,991,670 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01361,067,046 - 61,138,949 (+)NCBIUU_Cfam_GSD_1.0
Rufy3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528515,535,254 - 15,594,049 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365983,987,320 - 4,046,187 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365983,987,287 - 4,046,019 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUFY3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl867,495,033 - 67,582,142 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1867,494,552 - 67,582,144 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2871,403,191 - 71,490,372 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RUFY3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1719,214,051 - 19,316,840 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl719,232,434 - 19,300,550 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660843,562,094 - 3,671,841 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rufy3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248902,032,995 - 2,134,648 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248902,032,980 - 2,135,922 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rufy3
402 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:88
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000004776, ENSRNOT00000020608
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062228035204Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141103081230320092Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141487516830883947Rat
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141757341219726296Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat

Markers in Region
RH131654  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21419,431,907 - 19,432,110 (+)MAPPERmRatBN7.2
Rnor_6.01421,058,953 - 21,059,155NCBIRnor6.0
Rnor_5.01420,968,780 - 20,968,982UniSTSRnor5.0
RGSC_v3.41421,011,126 - 21,011,328UniSTSRGSC3.4
Celera1418,771,078 - 18,771,280UniSTS
RH 3.4 Map14285.4UniSTS
Cytogenetic Map14p22UniSTS
RH132885  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21419,441,212 - 19,441,424 (+)MAPPERmRatBN7.2
Rnor_6.01421,068,258 - 21,068,469NCBIRnor6.0
Rnor_5.01420,978,085 - 20,978,296UniSTSRnor5.0
RGSC_v3.41421,020,431 - 21,020,642UniSTSRGSC3.4
Celera1418,780,368 - 18,780,579UniSTS
RH 3.4 Map14292.4UniSTS
Cytogenetic Map14p22UniSTS
RH134531  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21419,441,569 - 19,441,752 (+)MAPPERmRatBN7.2
Rnor_6.01421,068,615 - 21,068,797NCBIRnor6.0
Rnor_5.01420,978,442 - 20,978,624UniSTSRnor5.0
RGSC_v3.41421,020,788 - 21,020,970UniSTSRGSC3.4
Celera1418,780,725 - 18,780,907UniSTS
RH 3.4 Map14289.9UniSTS
Cytogenetic Map14p22UniSTS
BG376722  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21419,432,743 - 19,432,885 (+)MAPPERmRatBN7.2
Rnor_6.01421,059,789 - 21,059,930NCBIRnor6.0
Rnor_5.01420,969,616 - 20,969,757UniSTSRnor5.0
RGSC_v3.41421,011,962 - 21,012,103UniSTSRGSC3.4
Celera1418,771,914 - 18,772,055UniSTS
RH 3.4 Map14285.4UniSTS
Cytogenetic Map14p22UniSTS
BI295036  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21419,488,641 - 19,488,777 (+)MAPPERmRatBN7.2
Rnor_6.01421,126,671 - 21,126,806NCBIRnor6.0
Rnor_5.01421,036,498 - 21,036,633UniSTSRnor5.0
RGSC_v3.41421,068,318 - 21,068,453UniSTSRGSC3.4
Celera1418,827,375 - 18,827,510UniSTS
RH 3.4 Map14293.6UniSTS
Cytogenetic Map14p22UniSTS
AW529895  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21419,435,598 - 19,435,803 (+)MAPPERmRatBN7.2
Rnor_6.01421,062,644 - 21,062,848NCBIRnor6.0
Rnor_5.01420,972,471 - 20,972,675UniSTSRnor5.0
RGSC_v3.41421,014,817 - 21,015,021UniSTSRGSC3.4
Celera1418,774,754 - 18,774,958UniSTS
RH 3.4 Map14285.3UniSTS
Cytogenetic Map14p22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 51 35 19 35 8 10 74 35 41 11 8
Low 8 6 6 6 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004776   ⟹   ENSRNOP00000004776
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1419,432,524 - 19,490,474 (-)Ensembl
Rnor_6.0 Ensembl1421,070,593 - 21,128,505 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000020608   ⟹   ENSRNOP00000020608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1419,432,524 - 19,489,839 (-)Ensembl
Rnor_6.0 Ensembl1421,070,610 - 21,127,868 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092172   ⟹   ENSRNOP00000073742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1419,432,524 - 19,489,839 (-)Ensembl
Rnor_6.0 Ensembl1421,058,595 - 21,127,875 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100042   ⟹   ENSRNOP00000093326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1419,443,548 - 19,507,004 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103075   ⟹   ENSRNOP00000096851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1419,432,524 - 19,507,004 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109188   ⟹   ENSRNOP00000078674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1419,432,524 - 19,479,766 (-)Ensembl
RefSeq Acc Id: NM_001025127   ⟹   NP_001020298
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81419,725,556 - 19,774,557 (-)NCBI
mRatBN7.21419,441,493 - 19,490,498 (-)NCBI
Rnor_6.01421,070,592 - 21,128,505 (-)NCBI
Rnor_5.01420,968,402 - 21,040,629 (-)NCBI
RGSC_v3.41421,022,765 - 21,070,152 (-)RGD
Celera1418,782,702 - 18,829,205 (-)RGD
Sequence:
RefSeq Acc Id: NM_001401613   ⟹   NP_001388542
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81419,715,593 - 19,790,530 (-)NCBI
mRatBN7.21419,431,530 - 19,506,476 (-)NCBI
RefSeq Acc Id: NM_001401614   ⟹   NP_001388543
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81419,725,556 - 19,790,530 (-)NCBI
mRatBN7.21419,441,493 - 19,506,476 (-)NCBI
RefSeq Acc Id: NM_001401615   ⟹   NP_001388544
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81419,725,556 - 19,774,557 (-)NCBI
mRatBN7.21419,441,493 - 19,490,498 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001020298   ⟸   NM_001025127
- Peptide Label: isoform 4
- UniProtKB: A5HLX7 (UniProtKB/Swiss-Prot),   A5JUR6 (UniProtKB/Swiss-Prot),   Q5FVJ0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073742   ⟸   ENSRNOT00000092172
RefSeq Acc Id: ENSRNOP00000004776   ⟸   ENSRNOT00000004776
RefSeq Acc Id: ENSRNOP00000020608   ⟸   ENSRNOT00000020608
RefSeq Acc Id: ENSRNOP00000093326   ⟸   ENSRNOT00000100042
RefSeq Acc Id: ENSRNOP00000078674   ⟸   ENSRNOT00000109188
RefSeq Acc Id: ENSRNOP00000096851   ⟸   ENSRNOT00000103075
RefSeq Acc Id: NP_001388542   ⟸   NM_001401613
- Peptide Label: isoform 1
- UniProtKB: A0A8I6ARF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388543   ⟸   NM_001401614
- Peptide Label: isoform 2
- UniProtKB: A0A8I6AK59 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388544   ⟸   NM_001401615
- Peptide Label: isoform 3
Protein Domains
RUN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVJ0-F1-model_v2 AlphaFold Q5FVJ0 1-469 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699241
Promoter ID:EPDNEW_R9766
Type:initiation region
Name:Rufy3_1
Description:RUN and FYVE domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01421,128,467 - 21,128,527EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565242 AgrOrtholog
BioCyc Gene G2FUF-16165 BioCyc
Ensembl Genes ENSRNOG00000003428 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004776.5 UniProtKB/TrEMBL
  ENSRNOT00000020608.7 UniProtKB/TrEMBL
  ENSRNOT00000092172.2 UniProtKB/TrEMBL
  ENSRNOT00000100042 ENTREZGENE
  ENSRNOT00000100042.1 UniProtKB/TrEMBL
  ENSRNOT00000103075 ENTREZGENE
  ENSRNOT00000103075.1 UniProtKB/TrEMBL
  ENSRNOT00000109188.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.900 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7312240 IMAGE-MGC_LOAD
InterPro RUFY1-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Run_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Run_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RUN_RUFY3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:360921 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109279 IMAGE-MGC_LOAD
NCBI Gene 360921 ENTREZGENE
PANTHER PROTEIN RUFY3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rufy3 PhenoGen
PROSITE RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003428 RatGTEx
SMART FYVE UniProtKB/TrEMBL
  RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF140741 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A0G2K6A9_RAT UniProtKB/TrEMBL
  A0A8I5ZLF4_RAT UniProtKB/TrEMBL
  A0A8I6AK59 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ARF6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q1K8_RAT UniProtKB/TrEMBL
  A0A8L2QAC6_RAT UniProtKB/TrEMBL
  A5HLX7 ENTREZGENE
  A5JUR6 ENTREZGENE
  Q5FVJ0 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A5HLX7 UniProtKB/Swiss-Prot
  A5JUR6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Rufy3  RUN and FYVE domain containing 3  Ripx  rap2 interacting protein x  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Ripx  rap2 interacting protein x      Symbol and Name status set to provisional 70820 PROVISIONAL