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Gene: Gadl1 (glutamate decarboxylase-like 1) Rattus norvegicus

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Symbol:

Gadl1

Name:

glutamate decarboxylase-like 1

RGD ID:

1565145

Description:

Predicted to enable carboxy-lyase activity. Predicted to be involved in carboxylic acid metabolic process. Predicted to be active in cytoplasm. Orthologous to human GADL1 (glutamate decarboxylase like 1); INTERACTS WITH atrazine; indometacin; methoxychlor.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

acidic amino acid decarboxylase GADL1; LOC367181; RGD1565145; similar to cysteine sulfinic acid decarboxylase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GADL1 (glutamate decarboxylase like 1)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Gadl1 (glutamate decarboxylase-like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gadl1 (glutamate decarboxylase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GADL1 (glutamate decarboxylase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GADL1 (glutamate decarboxylase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gadl1 (glutamate decarboxylase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GADL1 (glutamate decarboxylase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GADL1 (glutamate decarboxylase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gadl1 (glutamate decarboxylase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gadl1 (glutamate decarboxylase like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GADL1 (glutamate decarboxylase like 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GADL1 (glutamate decarboxylase like 1)	Alliance	DIOPT (HGNC)
Mus musculus (house mouse):	Gadl1 (glutamate decarboxylase-like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5618	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	gadl1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	124,483,736 - 124,663,815 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	124,417,051 - 124,663,023 (+)	Ensembl				GRCr8
mRatBN7.2	8	115,605,609 - 115,785,676 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	115,605,873 - 115,784,410 (+)	Ensembl				mRatBN7.2
Dahl_SR_JrHsd	8	125,364,095 - 125,543,795 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	8	127,464,852 - 127,647,659 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	8	125,950,778 - 126,133,585 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	8	117,358,700 - 117,541,505 (+)	NCBI		F344_StmMcwi
Rnor_6.0	8	123,989,822 - 124,301,366 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	123,477,133 - 123,574,752 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	8	123,277,396 - 123,349,979 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	120,428,678 - 120,579,318 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	114,821,749 - 115,000,979 (+)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Liver Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-trichloroethane (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,4,4'-trichlorobiphenyl (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

Butylbenzyl phthalate (ISO)

CGP 52608 (ISO)

indometacin (EXP)

lipopolysaccharide (ISO)

methoxychlor (EXP)

PCB138 (ISO)

phenobarbital (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium fluoride (ISO)

titanium dioxide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carboxylic acid metabolic process (IEA)

Cellular Component

cytoplasm (IBA)

Molecular Function

carbon-carbon lyase activity (IEA)

carboxy-lyase activity (IBA,IEA)

lyase activity (IEA)

pyridoxal phosphate binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Gadl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	124,483,736 - 124,663,815 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	124,417,051 - 124,663,023 (+)	Ensembl				GRCr8
mRatBN7.2	8	115,605,609 - 115,785,676 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	115,605,873 - 115,784,410 (+)	Ensembl				mRatBN7.2
Dahl_SR_JrHsd	8	125,364,095 - 125,543,795 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	8	127,464,852 - 127,647,659 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	8	125,950,778 - 126,133,585 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	8	117,358,700 - 117,541,505 (+)	NCBI		F344_StmMcwi
Rnor_6.0	8	123,989,822 - 124,301,366 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	123,477,133 - 123,574,752 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	8	123,277,396 - 123,349,979 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	120,428,678 - 120,579,318 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	114,821,749 - 115,000,979 (+)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

GADL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	30,726,197 - 30,894,661 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	30,726,197 - 30,894,761 (-)	Ensembl			hg38	GRCh38
GRCh37	3	30,767,689 - 30,936,153 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	30,742,696 - 30,867,341 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	30,742,695 - 30,867,341	NCBI
Celera	3	30,704,622 - 30,873,129 (-)	NCBI		Celera
Cytogenetic Map	3	p24.1-p23	NCBI
HuRef	3	30,710,278 - 30,878,749 (-)	NCBI		HuRef
CHM1_1	3	30,717,842 - 30,886,283 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	30,728,666 - 30,897,141 (-)	NCBI		T2T-CHM13v2.0

Gadl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	115,713,739 - 115,905,244 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	115,713,947 - 115,905,243 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	115,884,671 - 116,076,176 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	115,909,455 - 116,076,176 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	115,818,573 - 115,985,294 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	115,757,262 - 115,923,048 (+)	NCBI		MGSCv36	mm8
Celera	9	116,371,831 - 116,537,330 (+)	NCBI		Celera
Cytogenetic Map	9	F3	NCBI
cM Map	9	68.25	NCBI

Gadl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	22,029,450 - 22,188,133 (-)	Ensembl
ChiLan1.0	NW_004955430	22,029,481 - 22,187,807 (-)	NCBI	ChiLan1.0	ChiLan1.0

GADL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	30,715,117 - 30,884,075 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	30,719,883 - 30,888,841 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	30,655,701 - 30,824,656 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	30,975,196 - 31,141,989 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	30,975,196 - 31,142,703 (-)	Ensembl			panPan2	panpan1.1

GADL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	13,697,028 - 13,859,980 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	13,696,741 - 13,859,358 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	13,679,835 - 13,843,060 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	13,991,743 - 14,155,351 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	13,991,208 - 14,155,102 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	13,797,043 - 13,952,697 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	13,935,335 - 14,098,638 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	13,953,699 - 14,117,051 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gadl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	188,290,697 - 188,756,622 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	21,431,071 - 21,563,226 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	21,430,668 - 21,563,241 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GADL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	16,892,163 - 17,049,305 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	16,892,162 - 17,049,314 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	19,042,596 - 19,105,789 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GADL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	75,237,681 - 75,407,007 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	75,237,675 - 75,405,706 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	48,525,775 - 48,693,030 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gadl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624788	8,577,761 - 8,754,206 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624788	8,577,832 - 8,753,989 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gadl1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	107,197,595 - 107,338,990 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	25
Count of miRNA genes:	25
Interacting mature miRNAs:	25
Transcripts:	ENSRNOT00000017696
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
1599689	Iddm24	Insulin dependent diabetes mellitus QTL 24	4.72	0.001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	8	122879213	126360737	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

D8Rat119

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	8	124,619,885 - 124,620,065 (+)	Marker Load Pipeline
mRatBN7.2	8	115,741,740 - 115,741,920 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	124,240,117 - 124,240,296	NCBI	Rnor6.0
Rnor_5.0	8	123,517,546 - 123,517,725	UniSTS	Rnor5.0
RGSC_v3.4	8	120,530,641 - 120,530,821	RGD	RGSC3.4
RGSC_v3.4	8	120,530,642 - 120,530,821	UniSTS	RGSC3.4
Celera	8	114,955,855 - 114,956,034	UniSTS
RGSC_v3.1	8	120,550,379 - 120,550,558	RGD
RH 3.4 Map	8	1227.6	UniSTS
RH 3.4 Map	8	1227.6	RGD
RH 2.0 Map	8	982.3	RGD
SHRSP x BN Map	8	77.3899	RGD
Cytogenetic Map	8	q32	UniSTS

D8Got190

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	115,396,229 - 115,396,398 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	123,779,785 - 123,779,953	NCBI	Rnor6.0
Rnor_5.0	8	123,067,952 - 123,068,120	UniSTS	Rnor5.0
RGSC_v3.4	8	120,170,734 - 120,170,903	RGD	RGSC3.4
RGSC_v3.4	8	120,170,735 - 120,170,903	UniSTS	RGSC3.4
Celera	8	114,622,074 - 114,622,242	UniSTS
RGSC_v3.1	8	120,190,472 - 120,190,640	RGD
RH 3.4 Map	8	1216.4	UniSTS
RH 3.4 Map	8	1216.4	RGD
RH 2.0 Map	8	972.8	RGD
Cytogenetic Map	8	q32	UniSTS

D8Got189

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	115,536,710 - 115,536,916 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	123,922,017 - 123,922,222	NCBI	Rnor6.0
Rnor_5.0	8	123,209,873 - 123,210,078	UniSTS	Rnor5.0
RGSC_v3.4	8	120,313,341 - 120,313,546	RGD	RGSC3.4
RGSC_v3.4	8	120,313,342 - 120,313,547	UniSTS	RGSC3.4
Celera	8	74,456,026 - 74,456,231	UniSTS
RGSC_v3.1	8	120,333,078 - 120,333,283	RGD
RH 3.4 Map	8	1238.9	UniSTS
RH 3.4 Map	8	1238.9	RGD
Cytogenetic Map	8	q32	UniSTS

D8Got314

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	115,733,871 - 115,734,046 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	124,232,250 - 124,232,424	NCBI	Rnor6.0
Rnor_5.0	8	123,509,679 - 123,509,853	UniSTS	Rnor5.0
RGSC_v3.4	8	120,522,775 - 120,522,949	UniSTS	RGSC3.4
Celera	8	114,948,007 - 114,948,181	UniSTS
Cytogenetic Map	8	q32	UniSTS

AU049970

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	115,743,453 - 115,744,566 (+)	MAPPER	mRatBN7.2
mRatBN7.2	1	3,239,011 - 3,239,310 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	2,903,171 - 2,903,469	NCBI	Rnor6.0
Rnor_6.0	8	124,241,830 - 124,242,941	NCBI	Rnor6.0
Rnor_5.0	8	123,519,259 - 123,520,370	UniSTS	Rnor5.0
Rnor_5.0	1	4,585,130 - 4,585,428	UniSTS	Rnor5.0
RGSC_v3.4	1	3,440,260 - 3,440,558	UniSTS	RGSC3.4
RGSC_v3.4	8	120,532,355 - 120,533,466	UniSTS	RGSC3.4
Celera	8	114,957,568 - 114,958,679	UniSTS
Celera	1	1,783,314 - 1,783,612	UniSTS
Cytogenetic Map	8	q32	UniSTS
Cytogenetic Map	1	p13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
4	1	17	45	55	121	82	11	44	35	32	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001430390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001076997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082695	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	FQ217953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000117193 ⟹ ENSRNOP00000097428

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	124,417,051 - 124,662,510 (+)	Ensembl
mRatBN7.2 Ensembl	8	115,605,873 - 115,784,410 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000172052 ⟹ ENSRNOP00000102931

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	124,484,253 - 124,663,023 (+)	Ensembl

RefSeq Acc Id:

NM_001430390 ⟹ NP_001417319

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Dahl_SR_JrHsd	8	125,364,095 - 125,543,795 (+)	NCBI
Lyon_Normotensive	8	127,464,852 - 127,647,659 (+)	NCBI
Lyon_Hypertensive	8	125,950,778 - 126,133,585 (+)	NCBI
F344_StmMcwi	8	117,358,700 - 117,541,505 (+)	NCBI

RefSeq Acc Id:

XM_008766660 ⟹ XP_008764882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	124,483,736 - 124,663,815 (+)	NCBI
mRatBN7.2	8	115,605,609 - 115,785,676 (+)	NCBI
Rnor_6.0	8	123,989,822 - 124,301,366 (+)	NCBI

Sequence:

show sequence

CCCTGGCTCAAACTGTGTCTTCTTAGAGAGCCCCAGGCTGCCTCAAGAGGCGGGCACTGCAGCC
TGGGTGGCACAGCAGAGCAGTGGCGGGCTTGTCCTGGTCCCTAGCTGTCTCTGCCTGCACCTGT
GCGATCCAGAACGCTCCACCGCCGCAGCCCCAGCAGAGAAGCCCGGAGCCACGATGAGCCACGC
CTGCGACCGCCAGGATGCCAGCCAAGGAGACACTGACCAGAAGGAGATGACCCCTGGTAAGAAG
ATCCCTGTCTTCGTGGATGGGGTTGTACTTAATGGACCACAAACAGATGTGAAAGCTGGAGAAA
AATTTGTTGAAGAAGCCTGTAGGCTAATAATGGAAGAGGTGGTTTTGAAAGCTACGGACATCAA
TGAAAAGGTATGTGAGTGGCAGCCCCCTGAGCAGCTGAGGCAGCTCCTTGACCTGGAGATGAGG
GACACGGGAGAGTCACAGGACAAGCTGCTGAAACTCTGCCAAGATGTCATCCGCTACAGTGTCA
AAACCAACCATCCGAGATTTTTCAACCAGCTGTATGCGGGCCTTGACTATCACTCCTTGNGCTG
CCGGATTATAACAGAGGCACTGAACCCAAGCATTTATACGTATGAGGTGTCCCCAGTGTTTCTG
TTAGTGGAAGAGGCGGTTCTGAAGAAAATGATTGAATGTGTTGGCTGGAAAGAAGGGGATGGAA
TATTTAACCCAGGTGGCTCAGTCTCCAATATGTGTGCAATGAATTTAGCCAGATACAGACATTG
CCCTGATATCAAGGACAAAGGCCTGTCTGGTTTGCCAAGATTAATCCTTTTCACGTCGGCAGAG
TGTCATTACTCCATGAAGAAAGCGGCCTCCTTCCTTGGGATTGGCACCCAGAATGTGTACTTTG
TAGAAACGGATGGAAGAGGTAAAATGATACCAGAGGAGCTGGAGAAACAAATCTGGCAAGGGAA
ACAAGAGGGGGCAGTGCCGTTTCTCGTCTGTGCCACCTCTGGTACCACCGTGCTGGGCGCCTTT
GACCCCCTGGATGAGATTGCTGAGGTCTGTGAGAGGCATGGCCTCTGGCTCCATGTGGATGCCT
CTTGGGGCGGCTCGGCTTTGGTGTCCAGGAAGCACCGCCGGCTCCTGCATGGCATCCACAGGGC
TGACTCGGTGGCCTGGAACCCACACAAGATGCTGATGGCGGGAATCCAGTGCTCCGCTCTACTT
GTCAAGGACAAATCTGATCTTCTTAAGAAGTGCTACTCTGCCAAAGCGACATATCTGTTCCAGC
AGGATAAATTCTACGACGTCAGCTACGACACGGGAGACAAGTCCATCCAGTGTAGCAGGAGACC
TGATGCCTTCAAGTTCTGGATGACCTGGAAGGCTGTGGGCACATCAGGACTTGAGGAGAGAGTT
AATCGTGCCTTTGCTCTATCTCGGTACCTGGTCGACGAAATCAAGAAAAGAGAAGGCTTCAAGC
TGCTGATAGAACCTGAATATACCAATGTGTGCTTTTGGTACATTCCACCAAGTCTCCGAGAGAT
GGCGGAAGGACCGGAGTTCTGGAGAAAGCTCAGCTTGGTGGCCCCAGCCATTAAGGAGAAAATG
ATGAAAAAGGGGAGTCTCATGCTGGGCTACCAGCCCCACCGGGGGAAAGTCAACTTCTTCCGCC
AGGTGGTCATCAGCCCTCAAGTGAGCCGGGAAGACATGGACTTCCTGCTGGATGAGATAGACAG
CCTGGGTAGAGACATGTAGCCACGGCTTTCATCCCCCAGAGGCATCACTCCTGTCCTGGGGACG
GTCACGGATCCAGTGCATCTGAAGACTCACTAGACAGATGACGGTCCTGGTGAGATTAGGAAAC
ACGCCCGCTCCCCACACAGAAAACGCTAAGCAAATAGTCCTAAGGGTTCTTTGGCTGCCTGCTG
CTACTGCTTGTAGAACGGAGAAAGTAGACATTATAAAGAATTATTCTCTCAAATATCATCCTTT
GAAACAACCCCGAGGACACTTTAGGCAGTGCCACTCGGATGGATGCTGGTTTGTAAGCTCCCAT
TGCTCTCTAAAGAACACAGAAGCGCAATGTGGAGCTTACAGCAGTGAACCCCAGTGTGCCCCTG
TGCCACCAGCATCAGCACCGTCAGGGACTTACTAAAAATACAAATTCTCCAGCCTTACCCCACA
CCACCTGAATCAGAAACTCTGGCTGGTTCCAGCATCCTGAGGTTTAATAAGCCCAACAGGTGAG
TCTGATGCACAATAAATTCTGAGAGACAATGGTCCAGTGAAAAGCCTTTACAGCTGTTTTACCC
CCTAAAGGACATGTGATATTTCAGTAGCCTCTCAGCCAGTCTTTGAAAAATACAGACCACATCC
CCACACCTCGCTAGCTAGCTATATGCTAGAAATGGTTTCTCTTAACACTTAAAAAGTGGAAAAG
AATGTACAGCAAATGTGGGCTTGTTGAGTCATTTTTCTAGTAGGTAATCATGGGAAACTCAATA
GCCATAGTTCAGGTCCCATTCTGCCTTTAGTGAGACAGGGCAGCTTCTCGACTGATGGAAAATA
CCACTGAGGTCAGATAGTTTGCAATCCCATTATATTTTTTTGAAATATTCAAATATATATATAT
ATATATGTATATATATATATGCAAGAGAGGGAGAGATAGATAGATAGACTATATTAGATTCTTA
CAGCCTAAAGATACATGTTTTATTTGGGCTGAAGTGTTTTTGGGTTTCGTTTTTGTTTCAGGAG
TTACAATGAATCACTATTCTAATTCATCTGCATTATAAATTAGGGGAAGAAAACCAAACAGTTT
TGATCAATGATTAGAAAACATTAATCCACTTCTCCAAGCATGCTATTGGGTGGGGACAAACATT
GCAAGGCTGTGTGGGTCTCTGTCCCTCTTTTACATTTTGGAATGCACTTCTTATTTTCACTCTC
GGCTTTGTAGGGAATAAAATAAATTCCAGAAGTGAAGTCCAAGGTTGTACAACATCCTCCTTCT
CAAATTCTGCAATGTCAGTTAGAGTTTTCAGTGGTCTATCTTGAGCAGAGACTCTAGATTTAGA
GACCTCTCCGTGGAGGTCCCCTGTTGTTCCTGCAACGTGGATGACTGCAACTCTCTCTGGAACC
CACACCTTAGATTTATTTCTGGGGGTTTTCTTGACTAGGAACAGACAATCTGGAGACGACGTGT
ACATGAAGGCTATGTGTTGAGATTTGTCCAGGTGGGGGGCTTGCAATCGCCTGACGATGGATCA
CTAACTCCTGACATTTAAATTTTGAGAAATGGATGTGTACTGTGTAGTCTGCACCAAACATCTT
CATTGTAGACTGTGCAGCCTTTCACTGTCTCCACTCAGCAAAGGTATTTTCACTTCATTTCCTG
AATTACTTCAAACTCCCTGGTGGTGGGAGCTATCGTGCATGAGTTGACTCTCGTTGCCTTTTCA
AAATTGTTCTACATAGAGTGCTCCTAAGACTGATGCTTGAAATAAGTTGGATTCCATGAAATAA
AGATCTCTGTCAGCACTGTG

hide sequence

RefSeq Acc Id:

XM_039082694 ⟹ XP_038938622

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	124,484,951 - 124,663,815 (+)	NCBI
mRatBN7.2	8	115,606,793 - 115,785,676 (+)	NCBI

RefSeq Acc Id:

XM_039082695 ⟹ XP_038938623

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	124,488,432 - 124,663,815 (+)	NCBI
mRatBN7.2	8	115,609,881 - 115,785,676 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001417319	(Get FASTA)	NCBI Sequence Viewer
	XP_008764882	(Get FASTA)	NCBI Sequence Viewer
	XP_038938622	(Get FASTA)	NCBI Sequence Viewer
	XP_038938623	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000097428
	ENSRNOP00000097428.2
	ENSRNOP00000102931
	ENSRNOP00000102931.1

RefSeq Acc Id:

XP_008764882 ⟸ XM_008766660

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSHACDRQDASQGDTDQKEMTPGKKIPVFVDGVVLNGPQTDVKAGEKFVEEACRLIMEEVVLKA
TDINEKVCEWQPPEQLRQLLDLEMRDTGESQDKLLKLCQDVIRYSVKTNHPRFFNQLYAGLDYH
SLXCRIITEALNPSIYTYEVSPVFLLVEEAVLKKMIECVGWKEGDGIFNPGGSVSNMCAMNLAR
YRHCPDIKDKGLSGLPRLILFTSAECHYSMKKAASFLGIGTQNVYFVETDGRGKMIPEELEKQI
WQGKQEGAVPFLVCATSGTTVLGAFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHG
IHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKKCYSAKATYLFQQDKFYDVSYDTGDKSIQC
SRRPDAFKFWMTWKAVGTSGLEERVNRAFALSRYLVDEIKKREGFKLLIEPEYTNVCFWYIPPS
LREMAEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLD
EIDSLGRDM

hide sequence

RefSeq Acc Id:	XP_038938622 ⟸ XM_039082694
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AWC8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938623 ⟸ XM_039082695
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AWC8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000097428 ⟸ ENSRNOT00000117193

Ensembl Acc Id:

ENSRNOP00000102931 ⟸ ENSRNOT00000172052

RefSeq Acc Id:

NP_001417319 ⟸ NM_001430390

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565145	AgrOrtholog
BioCyc Gene	G2FUF-28870	BioCyc
Ensembl Genes	ENSRNOG00000067908	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000117193	ENTREZGENE
	ENSRNOT00000117193.2	UniProtKB/TrEMBL
	ENSRNOT00000172052	ENTREZGENE
	ENSRNOT00000172052.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.640.10	UniProtKB/TrEMBL
	3.90.1150.170	UniProtKB/TrEMBL
InterPro	PyrdxlP-dep_de-COase	UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase	UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_major	UniProtKB/TrEMBL
	Pyridoxal-P_BS	UniProtKB/TrEMBL
NCBI Gene	367181	ENTREZGENE
PANTHER	GLUTAMATE DECARBOXYLASE-RELATED	UniProtKB/TrEMBL
	PTHR45677:SF1	UniProtKB/TrEMBL
Pfam	Pyridoxal_deC	UniProtKB/TrEMBL
PhenoGen	Gadl1	PhenoGen
PROSITE	DDC_GAD_HDC_YDC	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000067908	RatGTEx
Superfamily-SCOP	SSF53383	UniProtKB/TrEMBL
UniProt	A0A8I6AWC8	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LMH7_RAT	UniProtKB/TrEMBL
	A6I3R7_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Gadl1	glutamate decarboxylase-like 1	Gadl1	glutamate decarboxylase-like 1	Data merged from RGD:149736146	737654	PROVISIONAL
2021-08-09	Gadl1	glutamate decarboxylase-like 1			Symbol and Name status set to provisional	45752	PROVISIONAL
2012-10-12	Gadl1	glutamate decarboxylase-like 1	RGD1565145	similar to cysteine sulfinic acid decarboxylase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1565145	similar to cysteine sulfinic acid decarboxylase	RGD1565145_predicted	similar to cysteine sulfinic acid decarboxylase (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1565145_predicted	similar to cysteine sulfinic acid decarboxylase (predicted)	LOC367181	similar to cysteine sulfinic acid decarboxylase	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC367181	similar to cysteine sulfinic acid decarboxylase			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD