Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cnst | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Cnst (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNST mRNA | CTD | PMID:22206623 | Cnst | Rat | 17beta-estradiol | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Estradiol results in increased expression of CNST mRNA | CTD | PMID:23397585 | Cnst | Rat | 17beta-estradiol | decreases expression | ISO | Cnst (Mus musculus) | 6480464 | Estradiol results in decreased expression of CNST mRNA | CTD | PMID:39298647 | Cnst | Rat | 2-bromohexadecanoic acid | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in more ... | CTD | PMID:38195004 | Cnst | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | CNST (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of CNST mRNA | CTD | PMID:30851411 | Cnst | Rat | 3-methylcholanthrene | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Methylcholanthrene results in increased expression of CNST mRNA | CTD | PMID:23397585 | Cnst | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Cnst (Mus musculus) | 6480464 | bisphenol S results in decreased expression of CNST mRNA | CTD | PMID:39298647 | Cnst | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CNST mRNA | CTD | PMID:30047161 | Cnst | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CNST mRNA | CTD | PMID:28959563 | Cnst | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of CNST mRNA | CTD | PMID:30047161 | Cnst | Rat | aristolochic acid A | decreases expression | ISO | CNST (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of CNST protein | CTD | PMID:33212167 | Cnst | Rat | arsane | affects methylation | ISO | CNST (Homo sapiens) | 6480464 | Arsenic affects the methylation of CNST gene | CTD | PMID:25304211 | Cnst | Rat | arsenic atom | affects methylation | ISO | CNST (Homo sapiens) | 6480464 | Arsenic affects the methylation of CNST gene | CTD | PMID:25304211 | Cnst | Rat | arsenite(3-) | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to CNST mRNA] | CTD | PMID:32406909 | Cnst | Rat | avobenzone | increases expression | ISO | CNST (Homo sapiens) | 6480464 | avobenzone results in increased expression of CNST mRNA | CTD | PMID:31016361 | Cnst | Rat | benzo[a]pyrene | decreases methylation | ISO | Cnst (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of CNST exon; Benzo(a)pyrene results in decreased methylation of CNST more ... | CTD | PMID:27901495 | Cnst | Rat | benzo[a]pyrene | affects methylation | ISO | CNST (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CNST promoter | CTD | PMID:27901495 | Cnst | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Cnst (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of CNST mRNA | CTD | PMID:34319233 | Cnst | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CNST mRNA | CTD | PMID:25181051|PMID:38750585 | Cnst | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CNST mRNA | CTD | PMID:30816183 | Cnst | Rat | bisphenol A | affects methylation | ISO | Cnst (Mus musculus) | 6480464 | bisphenol A affects the methylation of CNST promoter | CTD | PMID:27334623 | Cnst | Rat | butanal | increases expression | ISO | CNST (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of CNST mRNA | CTD | PMID:26079696 | Cnst | Rat | Butylbenzyl phthalate | decreases methylation | ISO | Cnst (Mus musculus) | 6480464 | butylbenzyl phthalate results in decreased methylation of CNST intron | CTD | PMID:28392331 | Cnst | Rat | cadmium atom | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in more ... | CTD | PMID:38195004 | Cnst | Rat | cadmium dichloride | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of CNST mRNA | CTD | PMID:23397585|PMID:38174414|PMID:38568856 | Cnst | Rat | cadmium dichloride | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in more ... | CTD | PMID:38195004 | Cnst | Rat | carbon nanotube | decreases expression | ISO | Cnst (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of CNST mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Cnst | Rat | copper(II) sulfate | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of CNST mRNA | CTD | PMID:19549813 | Cnst | Rat | DDE | decreases expression | ISO | CNST (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of CNST mRNA | CTD | PMID:38568856 | Cnst | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of CNST mRNA | CTD | PMID:23914054 | Cnst | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of CNST mRNA | CTD | PMID:21266533 | Cnst | Rat | dicrotophos | decreases expression | ISO | CNST (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of CNST mRNA | CTD | PMID:28302478 | Cnst | Rat | dimethoate | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Dimethoate results in increased expression of CNST mRNA | CTD | PMID:23397585 | Cnst | Rat | dorsomorphin | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Cnst | Rat | enzacamene | increases expression | ISO | CNST (Homo sapiens) | 6480464 | enzacamene results in increased expression of CNST mRNA | CTD | PMID:23397585 | Cnst | Rat | enzyme inhibitor | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Cnst | Rat | ethanol | affects splicing | ISO | Cnst (Mus musculus) | 6480464 | Ethanol affects the splicing of CNST mRNA | CTD | PMID:30319688 | Cnst | Rat | fenvalerate | increases expression | ISO | CNST (Homo sapiens) | 6480464 | fenvalerate results in increased expression of CNST mRNA | CTD | PMID:23397585 | Cnst | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of CNST mRNA | CTD | PMID:30307764 | Cnst | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of CNST mRNA | CTD | PMID:24793618 | Cnst | Rat | folic acid | multiple interactions | ISO | Cnst (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CNST mRNA | CTD | PMID:22206623 | Cnst | Rat | folic acid | decreases expression | ISO | Cnst (Mus musculus) | 6480464 | Folic Acid results in decreased expression of CNST mRNA | CTD | PMID:25629700 | Cnst | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of CNST mRNA | CTD | PMID:33387578 | Cnst | Rat | Iopanoic acid | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Iopanoic Acid results in increased expression of CNST mRNA | CTD | PMID:23397585 | Cnst | Rat | lead(0) | affects expression | ISO | CNST (Homo sapiens) | 6480464 | Lead affects the expression of CNST mRNA | CTD | PMID:28903495 | Cnst | Rat | methimazole | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Methimazole results in increased expression of CNST mRNA | CTD | PMID:23397585 | Cnst | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of CNST mRNA | CTD | PMID:30047161 | Cnst | Rat | methotrexate | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Methotrexate results in increased expression of CNST mRNA | CTD | PMID:24449571 | Cnst | Rat | methoxychlor | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Methoxychlor results in increased expression of CNST mRNA | CTD | PMID:23397585 | Cnst | Rat | nitrates | multiple interactions | ISO | Cnst (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of CNST more ... | CTD | PMID:35964746 | Cnst | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CNST mRNA | CTD | PMID:33387578 | Cnst | Rat | phenylmercury acetate | decreases expression | ISO | CNST (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of CNST mRNA | CTD | PMID:26272509 | Cnst | Rat | phenylmercury acetate | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Cnst | Rat | rac-lactic acid | decreases expression | ISO | CNST (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of CNST mRNA | CTD | PMID:30851411 | Cnst | Rat | resveratrol | multiple interactions | ISO | Cnst (Mus musculus) | 6480464 | Resveratrol inhibits the reaction [titanium dioxide results in increased expression of CNST mRNA] | CTD | PMID:31298478 | Cnst | Rat | resveratrol | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of CNST mRNA | CTD | PMID:23557933 | Cnst | Rat | SB 431542 | multiple interactions | ISO | CNST (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Cnst | Rat | sodium arsenite | decreases expression | ISO | CNST (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of CNST mRNA | CTD | PMID:28595984 | Cnst | Rat | sodium arsenite | increases expression | ISO | CNST (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of CNST mRNA | CTD | PMID:38568856 | Cnst | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of CNST mRNA | CTD | PMID:19281266 | Cnst | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of CNST mRNA | CTD | PMID:30047161 | Cnst | Rat | temozolomide | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Temozolomide results in increased expression of CNST mRNA | CTD | PMID:31758290 | Cnst | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CNST mRNA | CTD | PMID:34492290 | Cnst | Rat | thiram | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Thiram results in increased expression of CNST mRNA | CTD | PMID:38568856 | Cnst | Rat | titanium dioxide | multiple interactions | ISO | Cnst (Mus musculus) | 6480464 | Resveratrol inhibits the reaction [titanium dioxide results in increased expression of CNST mRNA] | CTD | PMID:31298478 | Cnst | Rat | titanium dioxide | decreases methylation | ISO | Cnst (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of CNST gene | CTD | PMID:35295148 | Cnst | Rat | titanium dioxide | increases expression | ISO | Cnst (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CNST mRNA | CTD | PMID:31298478 | Cnst | Rat | torcetrapib | increases expression | ISO | CNST (Homo sapiens) | 6480464 | torcetrapib results in increased expression of CNST mRNA | CTD | PMID:23228038 | Cnst | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of CNST mRNA | CTD | PMID:33387578 | Cnst | Rat | triphenyl phosphate | affects expression | ISO | CNST (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of CNST mRNA | CTD | PMID:37042841 | Cnst | Rat | tungsten | decreases expression | ISO | Cnst (Mus musculus) | 6480464 | Tungsten results in decreased expression of CNST mRNA | CTD | PMID:30912803 | Cnst | Rat | urethane | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Urethane results in increased expression of CNST mRNA | CTD | PMID:28818685 | Cnst | Rat | valproic acid | increases expression | ISO | Cnst (Mus musculus) | 6480464 | Valproic Acid results in increased expression of CNST mRNA | CTD | PMID:21427059 | Cnst | Rat | valproic acid | affects expression | ISO | CNST (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CNST mRNA | CTD | PMID:25979313 | Cnst | Rat | valproic acid | increases expression | ISO | CNST (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CNST mRNA | CTD | PMID:29154799 | | 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