Lima1 (LIM domain and actin binding 1) - Rat Genome Database

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Gene: Lima1 (LIM domain and actin binding 1) Rattus norvegicus
Analyze
Symbol: Lima1
Name: LIM domain and actin binding 1
RGD ID: 1564050
Description: Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in several processes, including cholesterol homeostasis; intestinal cholesterol absorption; and negative regulation of actin filament depolymerization. Predicted to be located in several cellular components, including brush border membrane; focal adhesion; and stress fiber. Predicted to be active in actin cytoskeleton and plasma membrane. Orthologous to human LIMA1 (LIM domain and actin binding 1); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: epithelial protein lost in neoplasm; eplin; LIM domain and actin-binding protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,780,556 - 132,880,343 (-)NCBIGRCr8
mRatBN7.27130,901,717 - 131,001,512 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,901,717 - 131,001,473 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,705,455 - 132,771,449 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,931,042 - 134,997,029 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,843,567 - 134,909,560 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,428,113 - 141,528,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,428,063 - 141,528,397 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,932,904 - 116,035,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,519,353 - 138,617,856 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7127,383,104 - 127,448,452 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
alpha-pinene  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
avobenzone  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
butan-1-ol  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
ferric oxide  (ISO)
FR900359  (ISO)
gallic acid  (ISO)
geldanamycin  (ISO)
glycidol  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
isobutanol  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenethyl isothiocyanate  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phytoestrogen  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
actin cytoskeleton  (IBA,ISO)
actin filament  (ISO,ISS)
brush border  (ISO)
brush border membrane  (IEA,ISO)
cleavage furrow  (IEA,ISO)
cytoplasm  (IEA)
cytosol  (IEA,ISO)
focal adhesion  (IEA,ISO,ISS)
plasma membrane  (IBA,ISO)
ruffle  (IEA,ISO,ISS)
stress fiber  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10618726   PMID:11179679   PMID:12566430   PMID:17875928   PMID:20309963   PMID:21423176   PMID:22114352   PMID:23106098   PMID:24625528   PMID:24694988   PMID:25468996   PMID:29880681  
PMID:35352799  


Genomics

Comparative Map Data
Lima1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,780,556 - 132,880,343 (-)NCBIGRCr8
mRatBN7.27130,901,717 - 131,001,512 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,901,717 - 131,001,473 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,705,455 - 132,771,449 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,931,042 - 134,997,029 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,843,567 - 134,909,560 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,428,113 - 141,528,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,428,063 - 141,528,397 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,932,904 - 116,035,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,519,353 - 138,617,856 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7127,383,104 - 127,448,452 (-)NCBICelera
Cytogenetic Map7q36NCBI
LIMA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381250,175,788 - 50,283,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1250,175,788 - 50,283,520 (-)EnsemblGRCh38hg38GRCh38
GRCh371250,569,571 - 50,677,303 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,855,838 - 48,963,539 (-)NCBINCBI36Build 36hg18NCBI36
Celera1249,365,319 - 49,473,110 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,602,746 - 47,710,458 (-)NCBIHuRef
CHM1_11250,535,584 - 50,643,310 (-)NCBICHM1_1
T2T-CHM13v2.01250,138,878 - 50,246,629 (-)NCBIT2T-CHM13v2.0
Lima1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,676,351 - 99,773,292 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,676,351 - 99,773,337 (-)EnsemblGRCm39 Ensembl
GRCm381599,778,468 - 99,875,477 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,778,470 - 99,875,456 (-)EnsemblGRCm38mm10GRCm38
MGSCv371599,608,899 - 99,705,887 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,606,542 - 99,648,106 (-)NCBIMGSCv36mm8
Celera15101,933,926 - 102,030,215 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Lima1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547730,073 - 827,783 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955547730,152 - 827,644 (-)NCBIChiLan1.0ChiLan1.0
LIMA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21043,906,684 - 44,014,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11243,903,440 - 44,010,800 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,473,223 - 38,580,511 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,370,497 - 39,476,142 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,399,611 - 39,476,142 (+)Ensemblpanpan1.1panPan2
LIMA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,473,151 - 4,561,916 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,473,179 - 4,561,574 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,696,216 - 41,784,478 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,521,775 - 4,611,296 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,521,772 - 4,611,296 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,487,057 - 4,576,041 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,476,006 - 4,565,713 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02742,091,081 - 42,179,519 (-)NCBIUU_Cfam_GSD_1.0
Lima1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,312,989 - 65,351,458 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,814,120 - 7,850,379 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,812,856 - 7,851,859 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIMA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl516,074,438 - 16,177,103 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1516,074,436 - 16,177,122 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,487,730 - 16,492,647 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LIMA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,403,808 - 46,508,278 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1146,403,826 - 46,508,249 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037199,611,967 - 199,715,309 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lima1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,052,503 - 2,149,130 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,052,575 - 2,146,485 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lima1
650 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:913
Count of miRNA genes:331
Interacting mature miRNAs:433
Transcripts:ENSRNOT00000066908
Prediction methods:Microtar, Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
Eplin-pending  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,942,622 - 130,943,078 (+)MAPPERmRatBN7.2
Rnor_6.07141,469,838 - 141,470,293NCBIRnor6.0
Rnor_5.0X115,974,627 - 115,975,082UniSTSRnor5.0
RGSC_v3.47138,558,096 - 138,558,551UniSTSRGSC3.4
Celera7127,423,704 - 127,424,159UniSTS
Cytogenetic Map7q36UniSTS
RH129854  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,901,804 - 130,901,987 (+)MAPPERmRatBN7.2
Rnor_6.07141,428,201 - 141,428,383NCBIRnor6.0
Rnor_5.0X115,932,992 - 115,933,174UniSTSRnor5.0
RGSC_v3.47138,517,505 - 138,517,687UniSTSRGSC3.4
Celera7127,383,192 - 127,383,374UniSTS
RH 3.4 Map71076.2UniSTS
Cytogenetic Map7q36UniSTS
AA944710  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X116,023,976 - 116,024,155UniSTSRnor5.0
RGSC_v3.47138,607,988 - 138,608,167UniSTSRGSC3.4
Celera7127,473,871 - 127,474,050UniSTS
RH 3.4 Map71076.5UniSTS
Cytogenetic Map7q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000091702   ⟹   ENSRNOP00000072604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,901,788 - 131,001,473 (-)Ensembl
Rnor_6.0 Ensembl7141,428,063 - 141,528,397 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109357   ⟹   ENSRNOP00000096626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,901,717 - 130,986,161 (-)Ensembl
RefSeq Acc Id: NM_001191615   ⟹   NP_001178544
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87132,780,556 - 132,880,343 (-)NCBI
mRatBN7.27130,901,717 - 131,001,512 (-)NCBI
Rnor_6.07141,428,113 - 141,494,785 (-)NCBI
Rnor_5.0X115,932,904 - 116,035,032 (-)NCBI
Celera7127,383,104 - 127,448,452 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257354   ⟹   XP_006257416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87132,780,562 - 132,864,723 (-)NCBI
mRatBN7.27130,901,717 - 130,985,890 (-)NCBI
Rnor_6.07141,428,113 - 141,513,682 (-)NCBI
Rnor_5.0X115,932,904 - 116,035,032 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178544 (Get FASTA)   NCBI Sequence Viewer  
  XP_006257416 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAT45543 (Get FASTA)   NCBI Sequence Viewer  
  ABG37967 (Get FASTA)   NCBI Sequence Viewer  
  EDL86966 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072604.1
  ENSRNOP00000096626.1
GenBank Protein F1LR10 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001178544   ⟸   NM_001191615
- UniProtKB: G3V8I6 (UniProtKB/Swiss-Prot),   F1LR10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257416   ⟸   XM_006257354
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AM55 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072604   ⟸   ENSRNOT00000091702
Ensembl Acc Id: ENSRNOP00000096626   ⟸   ENSRNOT00000109357
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LR10-F1-model_v2 AlphaFold F1LR10 1-755 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695652
Promoter ID:EPDNEW_R6176
Type:initiation region
Name:Lima1_1
Description:LIM domain and actin binding 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07141,528,417 - 141,528,477EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564050 AgrOrtholog
BioCyc Gene G2FUF-32056 BioCyc
Ensembl Genes ENSRNOG00000059801 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000091702.2 UniProtKB/Swiss-Prot
  ENSRNOT00000109357.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EPLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:300228 UniProtKB/Swiss-Prot
NCBI Gene 300228 ENTREZGENE
PANTHER PTHR24206 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24206:SF57 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lima1 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059801 RatGTEx
SMART LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AM55 ENTREZGENE, UniProtKB/TrEMBL
  F1LR10 ENTREZGENE
  G3V8I6 ENTREZGENE
  LIMA1_RAT UniProtKB/Swiss-Prot
UniProt Secondary G3V8I6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Lima1  LIM domain and actin binding 1  eplin  epithelial protein lost in neoplasm  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED