Gar1 (GAR1 ribonucleoprotein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Gar1 (GAR1 ribonucleoprotein) Rattus norvegicus
Analyze
Symbol: Gar1
Name: GAR1 ribonucleoprotein
RGD ID: 1563995
Description: Predicted to enable box H/ACA snoRNA binding activity and telomerase RNA binding activity. Involved in snoRNA guided rRNA pseudouridine synthesis. Part of box H/ACA snoRNP complex. Orthologous to human GAR1 (GAR1 ribonucleoprotein); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GAR1 homolog, ribonucleoprotein; GAR1 ribonucleoprotein homolog; GAR1 ribonucleoprotein homolog (yeast); h/ACA ribonucleoprotein complex subunit 1; LOC499709; Nola1; nucleolar protein family A member 1; nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs); similar to nucleolar protein family A, member 1; snoRNP protein GAR1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82221,049,471 - 221,056,749 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2221,049,473 - 221,056,749 (-)EnsemblGRCr8
mRatBN7.22218,375,231 - 218,382,509 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2218,375,353 - 218,382,524 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2226,060,286 - 226,067,566 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02223,959,973 - 223,967,253 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02218,817,626 - 218,824,906 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02235,250,453 - 235,258,464 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2235,250,453 - 235,257,731 (-)Ensemblrn6Rnor6.0
Rnor_5.0274,665,990 - 74,673,268 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42227,267,775 - 227,275,054 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2210,660,447 - 210,667,725 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aconitine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (EXP,ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
iron atom  (EXP)
iron(0)  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dichloride  (EXP)
nickel subsulfide  (EXP)
nitrates  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
6. Immunopurified small nucleolar ribonucleoprotein particles pseudouridylate rRNA independently of their association with phosphorylated Nopp140. Wang C, etal., Mol Cell Biol 2002 Dec;22(24):8457-66.
7. The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA. Watkins NJ and Bohnsack MT, Wiley Interdiscip Rev RNA. 2012 May-Jun;3(3):397-414. doi: 10.1002/wrna.117. Epub 2011 Nov 7.
Additional References at PubMed
PMID:10757788   PMID:15489334   PMID:18082603   PMID:19135898   PMID:20351177   PMID:22658674   PMID:22681889   PMID:24270157   PMID:29695869  


Genomics

Comparative Map Data
Gar1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82221,049,471 - 221,056,749 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2221,049,473 - 221,056,749 (-)EnsemblGRCr8
mRatBN7.22218,375,231 - 218,382,509 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2218,375,353 - 218,382,524 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2226,060,286 - 226,067,566 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02223,959,973 - 223,967,253 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02218,817,626 - 218,824,906 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02235,250,453 - 235,258,464 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2235,250,453 - 235,257,731 (-)Ensemblrn6Rnor6.0
Rnor_5.0274,665,990 - 74,673,268 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42227,267,775 - 227,275,054 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2210,660,447 - 210,667,725 (-)NCBICelera
Cytogenetic Map2q43NCBI
GAR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384109,815,510 - 109,824,737 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4109,815,500 - 109,825,575 (+)Ensemblhg38GRCh38
GRCh374110,736,666 - 110,745,893 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364110,956,115 - 110,965,342 (+)NCBIBuild 36Build 36hg18NCBI36
Build 344111,094,269 - 111,103,495NCBI
Celera4108,030,240 - 108,039,463 (+)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4106,468,787 - 106,478,009 (+)NCBIHuRef
CHM1_14110,713,156 - 110,722,381 (+)NCBICHM1_1
T2T-CHM13v2.04113,117,572 - 113,126,796 (+)NCBIT2T-CHM13v2.0
Gar1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393129,618,561 - 129,625,045 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3129,618,561 - 129,625,045 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383129,824,912 - 129,831,407 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3129,824,912 - 129,831,396 (-)Ensemblmm10GRCm38
MGSCv373129,527,830 - 129,534,314 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363129,816,942 - 129,823,178 (-)NCBIMGSCv36mm8
Celera3136,337,668 - 136,344,152 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map359.16NCBI
Gar1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955496475,579 - 483,030 (-)Ensembl
ChiLan1.0NW_004955496476,061 - 483,030 (-)NCBIChiLan1.0ChiLan1.0
GAR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23107,906,362 - 107,915,651 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14108,199,753 - 108,209,052 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04102,311,275 - 102,320,579 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14112,878,912 - 112,888,134 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4112,879,223 - 112,887,828 (+)EnsemblpanPan2panpan1.1
GAR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13229,995,710 - 30,004,545 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3229,996,148 - 30,004,536 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3212,025,443 - 12,043,375 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03230,207,427 - 30,225,345 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3230,216,948 - 30,245,664 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13230,201,712 - 30,219,616 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03229,944,865 - 29,962,702 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0329,886,399 - 9,904,243 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gar1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530110,936,187 - 10,944,501 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365631,006,517 - 1,014,808 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365631,006,475 - 1,014,808 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8112,400,005 - 112,414,033 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18112,401,114 - 112,414,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28120,483,851 - 120,497,033 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GAR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1757,713,245 - 57,722,831 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl757,713,881 - 57,722,224 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603736,365,953 - 36,375,519 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gar1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462483094,090 - 102,155 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462483094,929 - 102,170 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Gar1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1329,472,720 - 29,479,302 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gar1
69 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:43
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000013149
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631563Hcuc3Hepatic copper content QTL 33.87liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2212145502231732847Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2202029709236904960Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2210956252251712708Rat
8693697Alc36Alcohol consumption QTL 3620.592drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2219814164239320906Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2214404877251712708Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2205135267225627153Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2204795005249795005Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2214404877251712708Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2218051934251712708Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2186850607231850607Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2192287802237287802Rat
1302789Stl26Serum triglyceride level QTL 263.10.0035blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)2206613059226891081Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2214404877251712708Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2196140964251540988Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2214404877251712708Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2205135267250135267Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2188565047233565047Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2192287802229609668Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2182635347227635347Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631203Gluco14Glucose level QTL 140.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)2209350500221678003Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2203664411248664411Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2214404877251712708Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2192287802221089121Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2192287802237287802Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2182024327227024327Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000078074   ⟹   ENSRNOP00000074835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2221,049,550 - 221,056,749 (-)Ensembl
mRatBN7.2 Ensembl2218,375,353 - 218,382,524 (-)Ensembl
Rnor_6.0 Ensembl2235,250,453 - 235,257,731 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093472   ⟹   ENSRNOP00000076165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2235,252,216 - 235,257,464 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000139266   ⟹   ENSRNOP00000099341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2221,049,631 - 221,056,749 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156769   ⟹   ENSRNOP00000104797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2221,049,473 - 221,056,749 (-)Ensembl
RefSeq Acc Id: NM_001024306   ⟹   NP_001019477
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82221,049,471 - 221,056,749 (-)NCBI
mRatBN7.22218,375,231 - 218,382,509 (-)NCBI
Rnor_6.02235,250,453 - 235,257,731 (-)NCBI
Rnor_5.0274,665,990 - 74,673,268 (+)NCBI
RGSC_v3.42227,267,775 - 227,275,054 (-)RGD
Celera2210,660,447 - 210,667,725 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001019477 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79131 (Get FASTA)   NCBI Sequence Viewer  
  EDL82185 (Get FASTA)   NCBI Sequence Viewer  
  EDL82186 (Get FASTA)   NCBI Sequence Viewer  
  EDL82187 (Get FASTA)   NCBI Sequence Viewer  
  Q6AYA1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001019477   ⟸   NM_001024306
- UniProtKB: Q6AYA1 (UniProtKB/Swiss-Prot),   A6HVQ1 (UniProtKB/TrEMBL),   A6HVP9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074835   ⟸   ENSRNOT00000078074
Ensembl Acc Id: ENSRNOP00000076165   ⟸   ENSRNOT00000093472
Ensembl Acc Id: ENSRNOP00000104797   ⟸   ENSRNOT00000156769
Ensembl Acc Id: ENSRNOP00000099341   ⟸   ENSRNOT00000139266

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYA1-F1-model_v2 AlphaFold Q6AYA1 1-226 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691756
Promoter ID:EPDNEW_R2274
Type:initiation region
Name:Gar1_1
Description:GAR1 ribonucleoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2275  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02235,257,492 - 235,257,552EPDNEW
RGD ID:13691750
Promoter ID:EPDNEW_R2275
Type:multiple initiation site
Name:Gar1_2
Description:GAR1 ribonucleoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2274  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02235,257,744 - 235,257,804EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563995 AgrOrtholog
BioCyc Gene G2FUF-51237 BioCyc
Ensembl Genes ENSRNOG00000061146 Ensembl
Gene3D-CATH 2.40.10.230 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7127379 IMAGE-MGC_LOAD
InterPro Gar1/Naf1_Cbf5-bd_sf UniProtKB/Swiss-Prot
  H/ACA_rnp_Gar1/Naf1 UniProtKB/Swiss-Prot
  Transl_B-barrel_sf UniProtKB/Swiss-Prot
KEGG Report rno:499709 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94141 IMAGE-MGC_LOAD
NCBI Gene 499709 ENTREZGENE
PANTHER H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 UniProtKB/Swiss-Prot
  NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 UniProtKB/Swiss-Prot
Pfam Gar1 UniProtKB/Swiss-Prot
PhenoGen Gar1 PhenoGen
RatGTEx ENSRNOG00000061146 RatGTEx
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot
UniProt A0A8L2R9E9_RAT UniProtKB/TrEMBL
  A0ABK0L5A6_RAT UniProtKB/TrEMBL
  A0ABK0L646_RAT UniProtKB/TrEMBL
  A6HVP9 ENTREZGENE, UniProtKB/TrEMBL
  A6HVQ1 ENTREZGENE, UniProtKB/TrEMBL
  GAR1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Gar1  GAR1 ribonucleoprotein  Gar1  GAR1 homolog, ribonucleoprotein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-09 Gar1  GAR1 homolog, ribonucleoprotein  Gar1  GAR1 ribonucleoprotein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-07 Gar1  GAR1 ribonucleoprotein  Gar1  GAR1 ribonucleoprotein homolog (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Gar1  GAR1 ribonucleoprotein homolog (yeast)  Nola1  nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Nola1  nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)  LOC499709  similar to nucleolar protein family A, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC499709  similar to nucleolar protein family A, member 1      Symbol and Name status set to provisional 70820 PROVISIONAL