Hcfc1 (host cell factor C1) - Rat Genome Database

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Gene: Hcfc1 (host cell factor C1) Rattus norvegicus
Analyze
Symbol: Hcfc1
Name: host cell factor C1
RGD ID: 1563804
Description: Predicted to enable several functions, including DNA binding activity; identical protein binding activity; and transcription coactivator activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and positive regulation of transcription by RNA polymerase II. Located in axon; dendrite; and nuclear chromosome. Human ortholog(s) of this gene implicated in methylmalonic acidemia and homocysteinemia cblX type. Orthologous to human HCFC1 (host cell factor C1); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C1 factor; HCF; HCF-1; host cell factor 1; host cell factor 1-like; LOC100911260; LOC363519; RGD1563804; similar to HCF
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,839,100 - 156,864,132 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX156,839,100 - 156,863,813 (-)EnsemblGRCr8
mRatBN7.2X151,687,779 - 151,712,688 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,687,779 - 151,712,638 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX153,828,944 - 153,853,809 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X157,392,162 - 157,417,027 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X155,063,993 - 155,088,858 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X156,812,012 - 156,837,227 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,812,064 - 156,837,227 (+)Ensemblrn6Rnor6.0
Rnor_5.01152,560,125 - 152,585,295 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X159,875,671 - 159,900,536 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1136,179,593 - 136,204,387 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
amphetamine  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carmustine  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flavonoids  (ISO)
folic acid  (ISO)
FR900359  (ISO)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
nitrates  (ISO)
oxaliplatin  (EXP)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
thapsigargin  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The transcriptional co-regulator HCF-1 is required for INS-1 β-cell glucose-stimulated insulin secretion. Iwata TN, etal., PLoS One. 2013 Nov 8;8(11):e78841. doi: 10.1371/journal.pone.0078841. eCollection 2013.
3. Transient reversal of episome silencing precedes VP16-dependent transcription during reactivation of latent HSV-1 in neurons. Kim JY, etal., PLoS Pathog. 2012 Feb;8(2):e1002540. doi: 10.1371/journal.ppat.1002540. Epub 2012 Feb 23.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO. Rizki G, etal., PLoS Genet. 2011 Sep;7(9):e1002235. doi: 10.1371/journal.pgen.1002235. Epub 2011 Sep 1.
9. The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Shilatifard A Annu Rev Biochem. 2012;81:65-95. doi: 10.1146/annurev-biochem-051710-134100.
Additional References at PubMed
PMID:7876203   PMID:9199328   PMID:9990006   PMID:10623756   PMID:10675337   PMID:12670868   PMID:15960975   PMID:17998332   PMID:18836447   PMID:18838386   PMID:18838538   PMID:19188440  
PMID:19946888   PMID:20018852   PMID:20091349   PMID:21285374   PMID:23629655   PMID:25468996   PMID:27869233   PMID:31505169  


Genomics

Comparative Map Data
Hcfc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,839,100 - 156,864,132 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX156,839,100 - 156,863,813 (-)EnsemblGRCr8
mRatBN7.2X151,687,779 - 151,712,688 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,687,779 - 151,712,638 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX153,828,944 - 153,853,809 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X157,392,162 - 157,417,027 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X155,063,993 - 155,088,858 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X156,812,012 - 156,837,227 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,812,064 - 156,837,227 (+)Ensemblrn6Rnor6.0
Rnor_5.01152,560,125 - 152,585,295 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X159,875,671 - 159,900,536 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1136,179,593 - 136,204,387 (+)NCBICelera
Cytogenetic MapXq37NCBI
HCFC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X153,947,557 - 153,971,818 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX153,946,434 - 153,972,427 (-)Ensemblhg38GRCh38
GRCh37X153,213,008 - 153,237,269 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,866,202 - 152,890,013 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X152,733,854 - 152,751,024NCBI
CeleraX153,446,719 - 153,470,530 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX141,865,579 - 141,889,655 (-)NCBIHuRef
CHM1_1X153,087,420 - 153,111,232 (-)NCBICHM1_1
T2T-CHM13v2.0X152,221,276 - 152,245,538 (-)NCBIT2T-CHM13v2.0
Hcfc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,986,400 - 73,011,430 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,986,398 - 73,009,963 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X73,942,792 - 73,966,995 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,942,792 - 73,966,357 (-)Ensemblmm10GRCm38
MGSCv37X71,188,134 - 71,211,654 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X70,195,515 - 70,219,035 (-)NCBIMGSCv36mm8
CeleraX65,195,177 - 65,218,707 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.52NCBI
Hcfc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580616,477 - 635,597 (-)Ensembl
ChiLan1.0NW_004955580616,477 - 636,849 (-)NCBIChiLan1.0ChiLan1.0
HCFC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X153,992,138 - 154,016,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X153,995,743 - 154,020,048 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X143,502,159 - 143,526,418 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X153,389,853 - 153,412,997 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,389,859 - 153,412,999 (-)EnsemblpanPan2panpan1.1
HCFC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X121,790,585 - 121,815,395 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX121,791,660 - 121,814,715 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX107,119,345 - 107,144,129 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X124,931,866 - 124,956,652 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX124,931,873 - 124,956,565 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X120,701,137 - 120,725,917 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X123,216,537 - 123,241,305 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X122,977,879 - 123,002,669 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hcfc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,089,236 - 119,116,163 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936809827,031 - 853,644 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936809827,008 - 853,689 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HCFC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,673,128 - 124,694,152 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X124,673,125 - 124,694,846 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X142,237,954 - 142,259,562 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HCFC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,371,518 - 128,395,920 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX128,371,517 - 128,394,861 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606566,242,868 - 66,267,283 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hcfc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946571,774 - 590,247 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624946571,776 - 591,543 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hcfc1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X128,562,581 - 128,634,555 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:496
Count of miRNA genes:258
Interacting mature miRNAs:316
Transcripts:ENSRNOT00000066182
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat

Markers in Region
U53925  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X151,689,200 - 151,689,353 (-)MAPPERmRatBN7.2
Rnor_6.0X156,835,654 - 156,835,806NCBIRnor6.0
Rnor_6.0X156,769,567 - 156,769,719NCBIRnor6.0
Rnor_5.01152,517,635 - 152,517,787UniSTSRnor5.0
Rnor_5.01152,583,722 - 152,583,874UniSTSRnor5.0
RGSC_v3.4X159,877,092 - 159,877,244UniSTSRGSC3.4
Celera1136,202,885 - 136,203,037UniSTS
Cytogenetic MapXq37UniSTS
RH128039  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X151,688,035 - 151,688,215 (-)MAPPERmRatBN7.2
Rnor_6.0X156,770,704 - 156,770,883NCBIRnor6.0
Rnor_6.0X156,836,791 - 156,836,970NCBIRnor6.0
Rnor_5.01152,584,859 - 152,585,038UniSTSRnor5.0
Rnor_5.01152,518,772 - 152,518,951UniSTSRnor5.0
RGSC_v3.4X159,875,928 - 159,876,107UniSTSRGSC3.4
Celera1136,203,951 - 136,204,130UniSTS
RH 3.4 Map5583.6UniSTS
Cytogenetic MapXq37UniSTS
REN88306  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01152,577,409 - 152,577,647NCBIRnor5.0
RGSC_v3.4X159,883,014 - 159,883,251UniSTSRGSC3.4
Cytogenetic MapXq37UniSTS
REN88319  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X151,697,733 - 151,697,997 (-)MAPPERmRatBN7.2
Rnor_6.0X156,826,705 - 156,826,968NCBIRnor6.0
Rnor_5.01152,574,773 - 152,575,036UniSTSRnor5.0
RGSC_v3.4X159,885,625 - 159,885,888UniSTSRGSC3.4
Celera1136,194,241 - 136,194,504UniSTS
Cytogenetic MapXq37UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000077142   ⟹   ENSRNOP00000073793
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,687,779 - 151,712,638 (-)Ensembl
Rnor_6.0 EnsemblX156,812,064 - 156,837,227 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112258   ⟹   ENSRNOP00000081395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX156,841,005 - 156,863,813 (-)Ensembl
mRatBN7.2 EnsemblX151,689,306 - 151,712,638 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113938   ⟹   ENSRNOP00000084541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX156,839,100 - 156,863,813 (-)Ensembl
mRatBN7.2 EnsemblX151,687,779 - 151,712,638 (-)Ensembl
RefSeq Acc Id: NM_001414734   ⟹   NP_001401663
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,839,100 - 156,863,813 (-)NCBI
mRatBN7.2X151,687,779 - 151,712,493 (-)NCBI
RefSeq Acc Id: XM_006229593   ⟹   XP_006229655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,839,110 - 156,864,132 (-)NCBI
mRatBN7.2X151,687,788 - 151,712,688 (-)NCBI
Rnor_6.0X156,812,012 - 156,837,217 (+)NCBI
Rnor_5.01152,560,125 - 152,585,295 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229594   ⟹   XP_006229656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,839,110 - 156,864,132 (-)NCBI
mRatBN7.2X151,687,788 - 151,712,688 (-)NCBI
Rnor_6.0X156,812,012 - 156,837,217 (+)NCBI
Rnor_5.01152,560,125 - 152,585,295 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229596   ⟹   XP_006229658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,839,110 - 156,864,132 (-)NCBI
mRatBN7.2X151,687,788 - 151,712,687 (-)NCBI
Rnor_6.0X156,812,013 - 156,837,217 (+)NCBI
Rnor_5.01152,560,125 - 152,585,295 (+)NCBI
Sequence:
RefSeq Acc Id: XP_006229655   ⟸   XM_006229593
- Peptide Label: isoform X1
- UniProtKB: D3ZN95 (UniProtKB/Swiss-Prot),   A0A8I5ZS53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229656   ⟸   XM_006229594
- Peptide Label: isoform X2
- UniProtKB: D3ZN95 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006229658   ⟸   XM_006229596
- Peptide Label: isoform X3
- UniProtKB: D3ZN95 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073793   ⟸   ENSRNOT00000077142
Ensembl Acc Id: ENSRNOP00000081395   ⟸   ENSRNOT00000112258
Ensembl Acc Id: ENSRNOP00000084541   ⟸   ENSRNOT00000113938
RefSeq Acc Id: NP_001401663   ⟸   NM_001414734
- UniProtKB: D3ZN95 (UniProtKB/Swiss-Prot),   A6KRT1 (UniProtKB/TrEMBL)
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZN95-F1-model_v2 AlphaFold D3ZN95 1-2034 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563804 AgrOrtholog
BioCyc Gene G2FUF-651 BioCyc
Ensembl Genes ENSRNOG00000051948 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000112258 ENTREZGENE
  ENSRNOT00000113938 ENTREZGENE
Gene3D-CATH 2.120.10.80 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
  6.10.250.2590 UniProtKB/Swiss-Prot
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  HCF1/2 UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
NCBI Gene 363519 ENTREZGENE
PANTHER PTHR46003 UniProtKB/Swiss-Prot
  PTHR46003:SF3 UniProtKB/Swiss-Prot
Pfam Kelch_5 UniProtKB/Swiss-Prot
PhenoGen Hcfc1 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000051948 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
UniProt A0A8I5ZS53 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A285_RAT UniProtKB/TrEMBL
  A6KRT1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZN95 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Hcfc1  host cell factor C1  LOC100911260  host cell factor 1-like  Data merged from RGD:6493784 737654 PROVISIONAL
2012-07-05 LOC100911260  host cell factor 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Hcfc1  host cell factor C1   Hcfc1_predicted  host cell factor C1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Hcfc1_predicted  host cell factor C1 (predicted)  RGD1563804_predicted  similar to HCF (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1563804_predicted  similar to HCF (predicted)  LOC363519  similar to HCF  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC363519  similar to HCF      Symbol and Name status set to provisional 70820 PROVISIONAL