Rps25l2 (ribosomal protein S25 like 2) - Rat Genome Database

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Gene: Rps25l2 (ribosomal protein S25 like 2) Rattus norvegicus
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Symbol: Rps25l2
Name: ribosomal protein S25 like 2
RGD ID: 1563613
Description: ENCODES a protein that exhibits structural constituent of ribosome (inferred); FOUND IN cytosolic small ribosomal subunit (inferred); ribonucleoprotein complex (inferred); ribosome (inferred); INTERACTS WITH indole-3-methanol; lead diacetate
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 40S ribosomal protein S25-like; LOC366605; RGD1563613; ribosomal protein S25 like; ribosomal protein S25 like 1; Rps25l1; similar to 40S ribosomal protein S25; small ribosomal subunit protein eS25-like
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8660,248,586 - 60,249,000 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2654,521,335 - 54,521,746 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.0657,396,178 - 57,396,594 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0666,991,875 - 66,992,293 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4656,592,837 - 56,593,211 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera653,635,777 - 53,636,193 (+)NCBICelera
Cytogenetic Map6q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:25931508  


Genomics

Variants

.
Variants in Rps25l2
10 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:21
Count of miRNA genes:20
Interacting mature miRNAs:21
Transcripts:ENSRNOT00000044779
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63902865963457441Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat


Expression

RNA-SEQ Expression

ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
sensory system
visual system
4 1 4 1 5 3 3 3

Sequence


RefSeq Acc Id: XM_039078186   ⟹   XP_038934114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8660,248,586 - 60,249,000 (+)NCBI
mRatBN7.2654,521,335 - 54,521,746 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038934114 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000033144.6
  ENSRNOP00000104267
  ENSRNOP00000104267.1
RefSeq Acc Id: XP_038934114   ⟸   XM_039078186
- UniProtKB: A0A0H2UHU0 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-37771 BioCyc
Ensembl Genes ENSRNOG00000027503 UniProtKB/TrEMBL
  ENSRNOG00000082176 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029546.6 UniProtKB/TrEMBL
  ENSRNOT00000173099 ENTREZGENE
  ENSRNOT00000173099.1 UniProtKB/TrEMBL
Gene3D-CATH Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain UniProtKB/TrEMBL
InterPro Ribosomal_S25 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene 366605 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S25 UniProtKB/TrEMBL
Pfam Ribosomal_S25 UniProtKB/TrEMBL
PhenoGen Rps25l2 PhenoGen
RatGTEx ENSRNOG00000027503 RatGTEx
  ENSRNOG00000082176 RatGTEx
UniProt A0A0H2UHU0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LQG4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-16 Rps25l2  ribosomal protein S25 like 2  Rps25l1  ribosomal protein S25 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Rps25l1  ribosomal protein S25 like 1  RGD1563613  similar to 40S ribosomal protein S25  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1563613  similar to 40S ribosomal protein S25   RGD1563613_predicted  similar to 40S ribosomal protein S25 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563613_predicted  similar to 40S ribosomal protein S25 (predicted)  LOC366605  similar to 40S ribosomal protein S25  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC366605  similar to 40S ribosomal protein S25      Symbol and Name status set to provisional 70820 PROVISIONAL