Cenpa (centromere protein A) - Rat Genome Database

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Gene: Cenpa (centromere protein A) Rattus norvegicus
Analyze
Symbol: Cenpa
Name: centromere protein A
RGD ID: 1563607
Description: Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in centromere complex assembly; establishment of mitotic spindle orientation; and mitotic cytokinesis. Predicted to act upstream of or within protein localization to chromosome, centromeric region. Predicted to be located in chromosome, centromeric region and nucleoplasm. Predicted to be part of CENP-A containing nucleosome. Human ortholog(s) of this gene implicated in autoimmune disease. Orthologous to human CENPA (centromere protein A); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: histone H3-like centromeric protein A; LOC298850; RGD1563607; similar to centromere protein A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,420,062 - 31,431,703 (-)NCBIGRCr8
mRatBN7.2625,700,142 - 25,711,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,700,142 - 25,711,675 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx626,004,502 - 26,011,743 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,320,374 - 26,327,620 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,800,027 - 25,807,259 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0627,072,259 - 27,080,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,072,166 - 27,080,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,887,831 - 36,896,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,686,603 - 25,693,840 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera625,193,302 - 25,201,670 (-)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CenpaRatautoimmune disease  ISOCENPA (Homo sapiens)36947376 RGD 
CenpaRathepatocellular carcinoma  ISOCENPA (Homo sapiens)36947377protein:increased expression:liver (human)RGD 
CenpaRatlung non-small cell carcinoma severityISOCENPA (Homo sapiens)9068941mRNA:increased expression:lung (human)RGDPMID:30008938 and REF_RGD_ID:36947379
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CenpaRatTatton-Brown-Rahman syndrome  ISOCENPA (Homo sapiens)8554872ClinVar Annotator: match by term: Tatton-Brown-Rahman overgrowth syndromeClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CenpaRathepatocellular carcinoma  ISOCENPA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28284560

1 to 20 of 177 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CenpaRat(-)-epigallocatechin 3-gallate multiple interactionsISOCENPA (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CENPA mRNACTDPMID:22079256
CenpaRat1,1-dichloroethene increases expressionISOCenpa (Mus musculus)6480464vinylidene chloride results in increased expression of CENPA mRNACTDPMID:26682919
CenpaRat1,2-dichloroethane decreases expressionISOCenpa (Mus musculus)6480464ethylene dichloride results in decreased expression of CENPA mRNACTDPMID:28189721 and PMID:28960355
CenpaRat1,2-dimethylhydrazine decreases expressionEXP 64804641 and 2-Dimethylhydrazine results in decreased expression of CENPA mRNACTDPMID:27840820
CenpaRat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of CENPA mRNACTDPMID:30723492
CenpaRat17alpha-ethynylestradiol increases expressionISOCenpa (Mus musculus)6480464Ethinyl Estradiol results in increased expression of CENPA mRNACTDPMID:17942748
CenpaRat17alpha-ethynylestradiol multiple interactionsISOCenpa (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CENPA mRNACTDPMID:17942748
CenpaRat17beta-estradiol increases expressionISOCenpa (Mus musculus)6480464Estradiol results in increased expression of CENPA mRNACTDPMID:25210133
CenpaRat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of CENPA mRNACTDPMID:32145629
CenpaRat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CENPA mRNACTDPMID:32741896
CenpaRat17beta-estradiol multiple interactionsISOCENPA (Homo sapiens)6480464Fulvestrant inhibits the reaction [Estradiol results in increased expression of CENPA mRNA]CTDPMID:31646340
CenpaRat17beta-estradiol increases expressionISOCENPA (Homo sapiens)6480464Estradiol results in increased expression of CENPA mRNACTDPMID:16474171 more ...
CenpaRat17beta-estradiol multiple interactionsISOCenpa (Mus musculus)6480464ESR1 protein promotes the reaction [Estradiol results in increased expression of CENPA mRNA]CTDPMID:25210133
CenpaRat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CENPA mRNACTDPMID:32741896
CenpaRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCenpa (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CENPA mRNACTDPMID:17942748
CenpaRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of CENPA mRNACTDPMID:33387578 and PMID:34747641
CenpaRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOCenpa (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of CENPA mRNACTDPMID:37172768
CenpaRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCenpa (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CENPA mRNACTDPMID:21570461
CenpaRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCENPA (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of CENPA mRNACTDPMID:21802500
CenpaRat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOCenpa (Mus musculus)64804642 more ...CTDPMID:38648751

1 to 20 of 177 rows

Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CenpaRatCENP-A containing chromatin assembly involved_inISOCENPA (Homo sapiens)1624291 PMID:11682612RGDPMID:11682612
CenpaRatCENP-A containing chromatin assembly involved_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatestablishment of mitotic spindle orientation involved_inISOCENPA (Homo sapiens)1624291 PMID:19468067RGDPMID:19468067
CenpaRatestablishment of mitotic spindle orientation involved_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatkinetochore assembly involved_inISOCENPA (Homo sapiens)1624291 PMID:11682612RGDPMID:11682612
CenpaRatkinetochore assembly involved_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatmitotic cytokinesis involved_inISOCENPA (Homo sapiens)1624291 PMID:27499292RGDPMID:27499292
CenpaRatmitotic cytokinesis involved_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatprotein localization to chromosome, centromeric region involved_inISOCENPA (Homo sapiens)1624291 PMID:11682612RGDPMID:11682612
CenpaRatprotein localization to chromosome, centromeric region involved_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatprotein localization to chromosome, centromeric region acts_upstream_of_or_withinISOCenpa (Mus musculus)1624291 PMID:22516971RGDPMID:22516971
1 to 11 of 11 rows

Cellular Component
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CenpaRatCENP-A containing chromatin located_inISOCenpa (Mus musculus)1624291 PMID:14519686RGDPMID:14519686
CenpaRatCENP-A containing nucleosome part_ofISOCENPA (Homo sapiens)1624291 PMID:18195732 and PMID:21743476RGDPMID:18195732 and PMID:21743476
CenpaRatCENP-A containing nucleosome part_ofIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatchromosome, centromeric region located_inISOCENPA (Homo sapiens)1624291 PMID:11084331 and PMID:27499292RGDPMID:11084331 and PMID:27499292
CenpaRatchromosome, centromeric region located_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatchromosome, centromeric region located_inISOCenpa (Mus musculus)1624291 PMID:22516971RGDPMID:22516971
CenpaRatcondensed chromosome, centromeric region located_inISOCENPA (Homo sapiens)1624291 PMID:11682612RGDPMID:11682612
CenpaRatcondensed chromosome, centromeric region located_inISOCenpa (Mus musculus)1624291 PMID:15242786RGDPMID:15242786
CenpaRatcondensed chromosome, centromeric region located_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatnucleoplasm located_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatnucleoplasm located_inISOCENPA (Homo sapiens) and UniProtKB:P49450-11624291 RGDGO_REF:0000052
CenpaRatnucleosome part_ofISOCENPA (Homo sapiens)1624291 PMID:27499292RGDPMID:27499292
CenpaRatnucleosome part_ofIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatnucleosome part_ofIEAInterPro:IPR0001641600115GO_REF:0000002InterProGO_REF:0000002
CenpaRatnucleus located_inIEAUniProtKB:P49450 and ensembl:ENSP000003368681600115GO_REF:0000107EnsemblGO_REF:0000107
CenpaRatnucleus located_inISOCENPA (Homo sapiens)1624291 PMID:27499292RGDPMID:27499292
CenpaRatpericentric heterochromatin located_inISOCenpa (Mus musculus)1624291 PMID:15242786RGDPMID:15242786
1 to 17 of 17 rows

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Hepatitis B virus X protein mutant upregulates CENP-A expression in hepatoma cells. Liu L, etal., Oncol Rep. 2012 Jan;27(1):168-73. doi: 10.3892/or.2011.1478. Epub 2011 Sep 28.
3. Autoepitopes on autoantigen centromere protein-A (CENP-A) are restricted to the N-terminal region, which has no homology with histone H3. Muro Y, etal., Clin Exp Immunol. 2000 Apr;120(1):218-23. doi: 10.1046/j.1365-2249.2000.01189.x.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11084331   PMID:11682612   PMID:12477932   PMID:14519686   PMID:15242786   PMID:18195732   PMID:19468067   PMID:21630459   PMID:22516971   PMID:27499292  



Cenpa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,420,062 - 31,431,703 (-)NCBIGRCr8
mRatBN7.2625,700,142 - 25,711,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,700,142 - 25,711,675 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx626,004,502 - 26,011,743 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,320,374 - 26,327,620 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,800,027 - 25,807,259 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0627,072,259 - 27,080,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,072,166 - 27,080,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,887,831 - 36,896,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,686,603 - 25,693,840 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera625,193,302 - 25,201,670 (-)NCBICelera
Cytogenetic Map6q14NCBI
CENPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38226,786,056 - 26,794,589 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl226,764,289 - 26,801,067 (+)EnsemblGRCh38hg38GRCh38
GRCh37227,008,924 - 27,017,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,862,386 - 26,870,961 (+)NCBINCBI36Build 36hg18NCBI36
Build 34226,920,571 - 26,929,105NCBI
Celera226,854,943 - 26,863,518 (+)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef226,750,612 - 26,759,190 (+)NCBIHuRef
CHM1_1226,938,614 - 26,947,189 (+)NCBICHM1_1
T2T-CHM13v2.0226,827,645 - 26,836,182 (+)NCBIT2T-CHM13v2.0
Cenpa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39530,824,214 - 30,832,181 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl530,824,121 - 30,832,174 (+)EnsemblGRCm39 Ensembl
GRCm38530,666,877 - 30,674,837 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl530,666,777 - 30,674,830 (+)EnsemblGRCm38mm10GRCm38
MGSCv37530,969,275 - 30,977,199 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36530,943,483 - 30,951,407 (+)NCBIMGSCv36mm8
Celera528,145,648 - 28,153,572 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.76NCBI
Cenpa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554698,799,071 - 8,819,876 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554698,799,312 - 8,819,637 (+)NCBIChiLan1.0ChiLan1.0
CENPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,713,881 - 99,728,841 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,717,857 - 99,732,808 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A26,785,301 - 26,800,178 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CENPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11720,808,320 - 20,833,747 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1720,811,663 - 20,819,568 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1720,705,452 - 20,727,630 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01721,132,793 - 21,155,222 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1721,132,865 - 21,141,662 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11720,819,646 - 20,841,970 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01720,831,002 - 20,853,359 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01720,877,019 - 20,899,384 (+)NCBIUU_Cfam_GSD_1.0
Cenpa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629265,118,691 - 65,128,436 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364935,714,782 - 5,720,837 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364935,715,274 - 5,720,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,263,915 - 112,272,621 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13112,263,912 - 112,272,638 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,263,793 - 119,272,512 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CENPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11480,838,049 - 80,847,609 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1480,839,335 - 80,846,608 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604531,298,072 - 31,307,015 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cenpa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247388,899,362 - 8,906,373 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247388,899,260 - 8,906,379 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Cenpa
60 total Variants

Predicted Target Of
Summary Value
Count of predictions:375
Count of miRNA genes:218
Interacting mature miRNAs:253
Transcripts:ENSRNOT00000012512
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat

1 to 10 of 33 rows
RH143311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2625,704,671 - 25,704,777 (+)MAPPERmRatBN7.2
Rnor_6.0628,306,143 - 28,306,248NCBIRnor6.0
Rnor_6.0627,073,542 - 27,073,647NCBIRnor6.0
Rnor_5.0638,115,420 - 38,115,525UniSTSRnor5.0
Rnor_5.0636,889,111 - 36,889,216UniSTSRnor5.0
RGSC_v3.4625,686,883 - 25,686,988UniSTSRGSC3.4
Celera625,194,585 - 25,194,690UniSTS
RH 3.4 Map6116.2UniSTS
Cytogenetic Map6q14UniSTS
AI045252  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2625,704,597 - 25,704,746 (+)MAPPERmRatBN7.2
Rnor_6.0628,306,069 - 28,306,217NCBIRnor6.0
Rnor_6.0627,073,468 - 27,073,616NCBIRnor6.0
Rnor_5.0638,115,346 - 38,115,494UniSTSRnor5.0
Rnor_5.0636,889,037 - 36,889,185UniSTSRnor5.0
RGSC_v3.4625,686,809 - 25,686,957UniSTSRGSC3.4
Celera625,194,511 - 25,194,659UniSTS
RH 3.4 Map6116.5UniSTS
Cytogenetic Map6q14UniSTS
RH141436  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2625,704,880 - 25,705,030 (+)MAPPERmRatBN7.2
Rnor_6.0628,306,352 - 28,306,501NCBIRnor6.0
Rnor_6.0627,073,751 - 27,073,900NCBIRnor6.0
Rnor_5.0638,115,629 - 38,115,778UniSTSRnor5.0
Rnor_5.0636,889,320 - 36,889,469UniSTSRnor5.0
RGSC_v3.4625,687,092 - 25,687,241UniSTSRGSC3.4
Celera625,194,794 - 25,194,943UniSTS
RH 3.4 Map696.2UniSTS
Cytogenetic Map6q14UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 49 112 91 90 59 25 59 6 217 97 92 45 60 31



Ensembl Acc Id: ENSRNOT00000012512   ⟹   ENSRNOP00000012512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl625,700,142 - 25,711,675 (-)Ensembl
Rnor_6.0 Ensembl627,072,166 - 27,080,856 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117984   ⟹   ENSRNOP00000083188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl625,700,142 - 25,711,622 (-)Ensembl
RefSeq Acc Id: NM_001106711   ⟹   NP_001100181
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,424,312 - 31,431,552 (-)NCBI
mRatBN7.2625,704,392 - 25,711,638 (-)NCBI
Rnor_6.0627,073,262 - 27,080,738 (-)NCBI
Rnor_5.0636,887,831 - 36,896,429 (-)NCBI
RGSC_v3.4625,686,603 - 25,693,840 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239798   ⟹   XP_006239860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,420,062 - 31,431,703 (-)NCBI
mRatBN7.2625,700,333 - 25,711,765 (-)NCBI
Rnor_6.0627,072,259 - 27,080,861 (-)NCBI
Rnor_5.0636,887,831 - 36,896,429 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594068   ⟹   XP_017449557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,423,307 - 31,431,703 (-)NCBI
mRatBN7.2625,700,142 - 25,711,767 (-)NCBI
Rnor_6.0627,072,259 - 27,080,863 (-)NCBI
Sequence:
1 to 10 of 10 rows
Protein RefSeqs NP_001100181 (Get FASTA)   NCBI Sequence Viewer  
  XP_006239860 (Get FASTA)   NCBI Sequence Viewer  
  XP_017449557 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66997 (Get FASTA)   NCBI Sequence Viewer  
  EDM02981 (Get FASTA)   NCBI Sequence Viewer  
  EDM02982 (Get FASTA)   NCBI Sequence Viewer  
  EDM02983 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012512.3
  ENSRNOP00000083188.1
  ENSRNOP00000103779
1 to 10 of 10 rows
RefSeq Acc Id: NP_001100181   ⟸   NM_001106711
- UniProtKB: B2RZ23 (UniProtKB/TrEMBL),   A6HAC7 (UniProtKB/TrEMBL),   F7EQM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239860   ⟸   XM_006239798
- Peptide Label: isoform X1
- UniProtKB: B2RZ23 (UniProtKB/TrEMBL),   A6HAC7 (UniProtKB/TrEMBL),   F7EQM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449557   ⟸   XM_017594068
- Peptide Label: isoform X2
- UniProtKB: A6HAC8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012512   ⟸   ENSRNOT00000012512
Ensembl Acc Id: ENSRNOP00000083188   ⟸   ENSRNOT00000117984
Histone H2A/H2B/H3

Name Modeler Protein Id AA Range Protein Structure
AF-B2RZ23-F1-model_v2 AlphaFold B2RZ23 1-159 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694462
Promoter ID:EPDNEW_R4985
Type:initiation region
Name:Cenpa_1
Description:centromere protein A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0627,080,820 - 27,080,880EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-38314 BioCyc
Ensembl Genes ENSRNOG00000032178 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000071944 ENTREZGENE
Ensembl Transcript ENSRNOT00000012512.7 UniProtKB/TrEMBL
  ENSRNOT00000117984.1 UniProtKB/TrEMBL
  ENSRNOT00000166400 ENTREZGENE
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8365241 IMAGE-MGC_LOAD
InterPro Histone-fold UniProtKB/TrEMBL
  Histone_core_D UniProtKB/TrEMBL
  Histone_H3 UniProtKB/TrEMBL
KEGG Report rno:298850 UniProtKB/TrEMBL
MGC_CLONE MGC:189150 IMAGE-MGC_LOAD
NCBI Gene 298850 ENTREZGENE
PANTHER CENTROMERE PROTEIN A UniProtKB/TrEMBL
  HISTONE H3.2 UniProtKB/TrEMBL
Pfam Histone UniProtKB/TrEMBL
PhenoGen Cenpa PhenoGen
PRINTS HISTONEH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032178 RatGTEx
  ENSRNOG00000071944 RatGTEx
SMART SM00428 UniProtKB/TrEMBL
Superfamily-SCOP Histone-fold UniProtKB/TrEMBL
UniProt A0A8I5ZWQ2_RAT UniProtKB/TrEMBL
  A6HAC7 ENTREZGENE, UniProtKB/TrEMBL
  A6HAC8 ENTREZGENE, UniProtKB/TrEMBL
  B2RZ23 ENTREZGENE
  F7EQM2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B2RZ23 UniProtKB/TrEMBL
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Cenpa  centromere protein A  RGD1563607_predicted  similar to centromere protein A (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563607_predicted  similar to centromere protein A (predicted)  LOC298850  similar to centromere protein A  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC298850  similar to centromere protein A      Symbol and Name status set to provisional 70820 PROVISIONAL