Cenpa (centromere protein A) - Rat Genome Database

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Gene: Cenpa (centromere protein A) Rattus norvegicus
Analyze
Symbol: Cenpa
Name: centromere protein A
RGD ID: 1563607
Description: Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in centromere complex assembly; establishment of mitotic spindle orientation; and mitotic cytokinesis. Predicted to act upstream of or within protein localization to chromosome, centromeric region. Predicted to be located in chromosome, centromeric region and nucleoplasm. Predicted to be part of CENP-A containing nucleosome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autoimmune disease. Orthologous to human CENPA (centromere protein A); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: histone H3-like centromeric protein A; LOC298850; RGD1563607; similar to centromere protein A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,420,062 - 31,431,703 (-)NCBIGRCr8
mRatBN7.2625,700,142 - 25,711,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,700,142 - 25,711,675 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx626,004,502 - 26,011,743 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,320,374 - 26,327,620 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,800,027 - 25,807,259 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0627,072,259 - 27,080,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,072,166 - 27,080,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,887,831 - 36,896,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,686,603 - 25,693,840 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera625,193,302 - 25,201,670 (-)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
arsenite(3-)  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
isobutanol  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
lucanthone  (ISO)
menadione  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
niclosamide  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorononanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Hepatitis B virus X protein mutant upregulates CENP-A expression in hepatoma cells. Liu L, etal., Oncol Rep. 2012 Jan;27(1):168-73. doi: 10.3892/or.2011.1478. Epub 2011 Sep 28.
3. Autoepitopes on autoantigen centromere protein-A (CENP-A) are restricted to the N-terminal region, which has no homology with histone H3. Muro Y, etal., Clin Exp Immunol. 2000 Apr;120(1):218-23. doi: 10.1046/j.1365-2249.2000.01189.x.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11084331   PMID:11682612   PMID:12477932   PMID:14519686   PMID:15242786   PMID:18195732   PMID:19468067   PMID:21630459   PMID:22516971   PMID:27499292  


Genomics

Comparative Map Data
Cenpa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,420,062 - 31,431,703 (-)NCBIGRCr8
mRatBN7.2625,700,142 - 25,711,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,700,142 - 25,711,675 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx626,004,502 - 26,011,743 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,320,374 - 26,327,620 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,800,027 - 25,807,259 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0627,072,259 - 27,080,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,072,166 - 27,080,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,887,831 - 36,896,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,686,603 - 25,693,840 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera625,193,302 - 25,201,670 (-)NCBICelera
Cytogenetic Map6q14NCBI
CENPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38226,786,056 - 26,794,589 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl226,764,289 - 26,801,067 (+)EnsemblGRCh38hg38GRCh38
GRCh37227,008,924 - 27,017,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,862,386 - 26,870,961 (+)NCBINCBI36Build 36hg18NCBI36
Build 34226,920,571 - 26,929,105NCBI
Celera226,854,943 - 26,863,518 (+)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef226,750,612 - 26,759,190 (+)NCBIHuRef
CHM1_1226,938,614 - 26,947,189 (+)NCBICHM1_1
T2T-CHM13v2.0226,827,645 - 26,836,182 (+)NCBIT2T-CHM13v2.0
Cenpa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39530,824,214 - 30,832,181 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl530,824,121 - 30,832,174 (+)EnsemblGRCm39 Ensembl
GRCm38530,666,877 - 30,674,837 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl530,666,777 - 30,674,830 (+)EnsemblGRCm38mm10GRCm38
MGSCv37530,969,275 - 30,977,199 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36530,943,483 - 30,951,407 (+)NCBIMGSCv36mm8
Celera528,145,648 - 28,153,572 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.76NCBI
Cenpa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554698,799,071 - 8,819,876 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554698,799,312 - 8,819,637 (+)NCBIChiLan1.0ChiLan1.0
CENPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,713,881 - 99,728,841 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,717,857 - 99,732,808 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A26,785,301 - 26,800,178 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CENPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11720,808,320 - 20,833,747 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1720,811,663 - 20,819,568 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1720,705,452 - 20,727,630 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01721,132,793 - 21,155,222 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1721,132,865 - 21,141,662 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11720,819,646 - 20,841,970 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01720,831,002 - 20,853,359 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01720,877,019 - 20,899,384 (+)NCBIUU_Cfam_GSD_1.0
Cenpa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629265,118,691 - 65,128,436 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364935,714,782 - 5,720,837 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364935,715,274 - 5,720,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,263,915 - 112,272,621 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13112,263,912 - 112,272,638 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,263,793 - 119,272,512 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CENPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11480,838,049 - 80,847,609 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1480,839,335 - 80,846,608 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604531,298,072 - 31,307,015 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cenpa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247388,899,362 - 8,906,373 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247388,899,260 - 8,906,379 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cenpa
60 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:375
Count of miRNA genes:218
Interacting mature miRNAs:253
Transcripts:ENSRNOT00000012512
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6127574569Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6127574569Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6127574569Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)61653614027261739Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6127574569Rat

Markers in Region
RH143311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2625,704,671 - 25,704,777 (+)MAPPERmRatBN7.2
Rnor_6.0628,306,143 - 28,306,248NCBIRnor6.0
Rnor_6.0627,073,542 - 27,073,647NCBIRnor6.0
Rnor_5.0638,115,420 - 38,115,525UniSTSRnor5.0
Rnor_5.0636,889,111 - 36,889,216UniSTSRnor5.0
RGSC_v3.4625,686,883 - 25,686,988UniSTSRGSC3.4
Celera625,194,585 - 25,194,690UniSTS
RH 3.4 Map6116.2UniSTS
Cytogenetic Map6q14UniSTS
AI045252  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2625,704,597 - 25,704,746 (+)MAPPERmRatBN7.2
Rnor_6.0628,306,069 - 28,306,217NCBIRnor6.0
Rnor_6.0627,073,468 - 27,073,616NCBIRnor6.0
Rnor_5.0638,115,346 - 38,115,494UniSTSRnor5.0
Rnor_5.0636,889,037 - 36,889,185UniSTSRnor5.0
RGSC_v3.4625,686,809 - 25,686,957UniSTSRGSC3.4
Celera625,194,511 - 25,194,659UniSTS
RH 3.4 Map6116.5UniSTS
Cytogenetic Map6q14UniSTS
RH141436  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2625,704,880 - 25,705,030 (+)MAPPERmRatBN7.2
Rnor_6.0628,306,352 - 28,306,501NCBIRnor6.0
Rnor_6.0627,073,751 - 27,073,900NCBIRnor6.0
Rnor_5.0638,115,629 - 38,115,778UniSTSRnor5.0
Rnor_5.0636,889,320 - 36,889,469UniSTSRnor5.0
RGSC_v3.4625,687,092 - 25,687,241UniSTSRGSC3.4
Celera625,194,794 - 25,194,943UniSTS
RH 3.4 Map696.2UniSTS
Cytogenetic Map6q14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 49 112 91 90 59 25 59 6 217 97 92 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000012512   ⟹   ENSRNOP00000012512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl625,700,142 - 25,711,675 (-)Ensembl
Rnor_6.0 Ensembl627,072,166 - 27,080,856 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117984   ⟹   ENSRNOP00000083188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl625,700,142 - 25,711,622 (-)Ensembl
RefSeq Acc Id: NM_001106711   ⟹   NP_001100181
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,424,312 - 31,431,552 (-)NCBI
mRatBN7.2625,704,392 - 25,711,638 (-)NCBI
Rnor_6.0627,073,262 - 27,080,738 (-)NCBI
Rnor_5.0636,887,831 - 36,896,429 (-)NCBI
RGSC_v3.4625,686,603 - 25,693,840 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239798   ⟹   XP_006239860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,420,062 - 31,431,703 (-)NCBI
mRatBN7.2625,700,333 - 25,711,765 (-)NCBI
Rnor_6.0627,072,259 - 27,080,861 (-)NCBI
Rnor_5.0636,887,831 - 36,896,429 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594068   ⟹   XP_017449557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,423,307 - 31,431,703 (-)NCBI
mRatBN7.2625,700,142 - 25,711,767 (-)NCBI
Rnor_6.0627,072,259 - 27,080,863 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001100181   ⟸   NM_001106711
- UniProtKB: B2RZ23 (UniProtKB/TrEMBL),   A6HAC7 (UniProtKB/TrEMBL),   F7EQM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239860   ⟸   XM_006239798
- Peptide Label: isoform X1
- UniProtKB: B2RZ23 (UniProtKB/TrEMBL),   A6HAC7 (UniProtKB/TrEMBL),   F7EQM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449557   ⟸   XM_017594068
- Peptide Label: isoform X2
- UniProtKB: A6HAC8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012512   ⟸   ENSRNOT00000012512
Ensembl Acc Id: ENSRNOP00000083188   ⟸   ENSRNOT00000117984
Protein Domains
Histone H2A/H2B/H3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RZ23-F1-model_v2 AlphaFold B2RZ23 1-159 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694462
Promoter ID:EPDNEW_R4985
Type:initiation region
Name:Cenpa_1
Description:centromere protein A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0627,080,820 - 27,080,880EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563607 AgrOrtholog
BioCyc Gene G2FUF-38314 BioCyc
Ensembl Genes ENSRNOG00000032178 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012512.7 UniProtKB/TrEMBL
  ENSRNOT00000117984.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8365241 IMAGE-MGC_LOAD
InterPro Histone-fold UniProtKB/TrEMBL
  Histone_core_D UniProtKB/TrEMBL
  Histone_H3 UniProtKB/TrEMBL
KEGG Report rno:298850 UniProtKB/TrEMBL
MGC_CLONE MGC:189150 IMAGE-MGC_LOAD
NCBI Gene 298850 ENTREZGENE
PANTHER CENTROMERE PROTEIN A UniProtKB/TrEMBL
  HISTONE H3.2 UniProtKB/TrEMBL
Pfam Histone UniProtKB/TrEMBL
PhenoGen Cenpa PhenoGen
PRINTS HISTONEH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032178 RatGTEx
SMART SM00428 UniProtKB/TrEMBL
Superfamily-SCOP Histone-fold UniProtKB/TrEMBL
UniProt A0A8I5ZWQ2_RAT UniProtKB/TrEMBL
  A6HAC7 ENTREZGENE, UniProtKB/TrEMBL
  A6HAC8 ENTREZGENE, UniProtKB/TrEMBL
  B2RZ23 ENTREZGENE
  F7EQM2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B2RZ23 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Cenpa  centromere protein A  RGD1563607_predicted  similar to centromere protein A (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563607_predicted  similar to centromere protein A (predicted)  LOC298850  similar to centromere protein A  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC298850  similar to centromere protein A      Symbol and Name status set to provisional 70820 PROVISIONAL