Saxo5 (stabilizer of axonemal microtubules 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Saxo5 (stabilizer of axonemal microtubules 5) Rattus norvegicus
Analyze
Symbol: Saxo5
Name: stabilizer of axonemal microtubules 5
RGD ID: 1563425
Description: Orthologous to human SAXO5 (stabilizer of axonemal microtubules 5); INTERACTS WITH bisphenol A; cadmium dichloride; furan.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC498129; LOC498129; RGD1563425; similar to FLJ35784 protein; testis expressed 45; testis-expressed protein 45; Tex45; uncharacterized protein C19orf45 homolog; uncharacterized protein LOC498129
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8126,318,845 - 6,336,018 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl126,318,903 - 6,336,009 (+)EnsemblGRCr8
mRatBN7.2121,520,983 - 1,538,127 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,521,014 - 1,538,118 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx122,191,775 - 2,202,436 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0122,815,341 - 2,826,003 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,587,372 - 1,598,026 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,016,035 - 2,033,140 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,016,058 - 2,033,112 (+)Ensemblrn6Rnor6.0
Rnor_5.0124,179,781 - 4,196,186 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4122,676,818 - 2,687,753 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera123,383,615 - 3,394,513 (+)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Saxo5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8126,318,845 - 6,336,018 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl126,318,903 - 6,336,009 (+)EnsemblGRCr8
mRatBN7.2121,520,983 - 1,538,127 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,521,014 - 1,538,118 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx122,191,775 - 2,202,436 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0122,815,341 - 2,826,003 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,587,372 - 1,598,026 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,016,035 - 2,033,140 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,016,058 - 2,033,112 (+)Ensemblrn6Rnor6.0
Rnor_5.0124,179,781 - 4,196,186 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4122,676,818 - 2,687,753 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera123,383,615 - 3,394,513 (+)NCBICelera
Cytogenetic Map12p12NCBI
SAXO5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38197,497,548 - 7,508,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl197,492,976 - 7,508,450 (+)Ensemblhg38GRCh38
GRCh37197,562,434 - 7,573,336 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,468,485 - 7,479,336 (+)NCBIBuild 36Build 36hg18NCBI36
Celera197,434,951 - 7,445,845 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef197,233,805 - 7,244,691 (+)NCBIHuRef
CHM1_1197,562,466 - 7,573,361 (+)NCBICHM1_1
T2T-CHM13v2.0197,498,219 - 7,509,163 (+)NCBIT2T-CHM13v2.0
Saxo5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,515,966 - 3,537,183 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl83,520,862 - 3,537,181 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3883,466,713 - 3,487,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,470,862 - 3,487,181 (+)Ensemblmm10GRCm38
MGSCv3783,470,862 - 3,487,178 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3683,470,862 - 3,487,181 (+)NCBIMGSCv36mm8
Celera83,696,734 - 3,713,152 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.92NCBI
Saxo5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555631,703,416 - 1,745,996 (-)Ensembl
ChiLan1.0NW_0049555631,723,768 - 1,729,831 (-)NCBIChiLan1.0ChiLan1.0
SAXO5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22012,169,095 - 12,180,981 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11911,287,227 - 11,298,197 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0196,788,323 - 6,799,578 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1197,647,908 - 7,657,380 (+)NCBIPanPan1.1PanPan1.1panPan2
SAXO5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,297,373 - 52,304,400 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2052,101,541 - 52,108,348 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02052,826,937 - 52,833,752 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2052,810,257 - 52,845,852 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12052,030,490 - 52,037,288 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02052,474,070 - 52,480,878 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02052,705,000 - 52,711,807 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Saxo5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118213,244,891 - 213,250,408 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365884,585,951 - 4,589,865 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365884,585,737 - 4,589,892 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SAXO5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,625,862 - 71,631,705 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1271,625,869 - 71,632,658 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2272,108,783 - 72,127,327 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SAXO5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.166,992,822 - 7,004,362 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl66,995,116 - 7,004,141 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666081864,000 - 883,654 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Saxo5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624828620,306 - 625,233 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624828618,820 - 625,239 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Saxo5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1161,399,507 - 1,409,736 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Saxo5
125 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:96
Interacting mature miRNAs:104
Transcripts:ENSRNOT00000049512
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12115486827Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1357337Gluco3Glucose level QTL 30.0004adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)12116966671Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
61334Gluco17Glucose level QTL 176.3adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)12116966671Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12111869600Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 1 7 56 29 29 15 20 15 4 74 40 5 42 9 37 14 6 6

Sequence


Ensembl Acc Id: ENSRNOT00000049512   ⟹   ENSRNOP00000046873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl126,318,903 - 6,336,009 (+)Ensembl
mRatBN7.2 Ensembl121,521,014 - 1,538,118 (+)Ensembl
Rnor_6.0 Ensembl122,016,058 - 2,033,112 (+)Ensembl
RefSeq Acc Id: NM_001109059   ⟹   NP_001102529
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,325,391 - 6,336,018 (+)NCBI
mRatBN7.2121,527,489 - 1,538,118 (+)NCBI
Rnor_6.0122,022,521 - 2,033,140 (+)NCBI
Rnor_5.0124,179,781 - 4,196,186 (+)NCBI
Celera123,383,615 - 3,394,513 (+)RGD
Sequence:
RefSeq Acc Id: XM_008768988   ⟹   XP_008767210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,318,845 - 6,336,012 (+)NCBI
mRatBN7.2121,520,983 - 1,538,127 (+)NCBI
Rnor_6.0122,016,035 - 2,033,140 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039089667   ⟹   XP_038945595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,318,871 - 6,336,012 (+)NCBI
mRatBN7.2121,520,983 - 1,537,994 (+)NCBI
RefSeq Acc Id: XM_039089668   ⟹   XP_038945596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,324,970 - 6,333,566 (+)NCBI
mRatBN7.2121,520,983 - 1,535,623 (+)NCBI
RefSeq Acc Id: XM_039089669   ⟹   XP_038945597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,325,817 - 6,336,012 (+)NCBI
mRatBN7.2121,527,915 - 1,538,125 (+)NCBI
RefSeq Acc Id: XM_039089670   ⟹   XP_038945598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,318,871 - 6,330,860 (+)NCBI
mRatBN7.2121,520,983 - 1,532,999 (+)NCBI
RefSeq Acc Id: XR_005491655
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,324,971 - 6,333,511 (+)NCBI
mRatBN7.2121,520,983 - 1,535,610 (+)NCBI
RefSeq Acc Id: XR_010056407
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,324,971 - 6,333,515 (+)NCBI
RefSeq Acc Id: NP_001102529   ⟸   NM_001109059
- UniProtKB: D3Z9Q6 (UniProtKB/TrEMBL),   A6KQ04 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767210   ⟸   XM_008768988
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000046873   ⟸   ENSRNOT00000049512
RefSeq Acc Id: XP_038945595   ⟸   XM_039089667
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038945596   ⟸   XM_039089668
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038945598   ⟸   XM_039089670
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038945597   ⟸   XM_039089669
- Peptide Label: isoform X4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z9Q6-F1-model_v2 AlphaFold D3Z9Q6 1-499 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698366
Promoter ID:EPDNEW_R8891
Type:single initiation site
Name:Tex45_1
Description:testis expressed 45
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0122,016,041 - 2,016,101EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563425 AgrOrtholog
BioCyc Gene G2FUF-20400 BioCyc
Ensembl Genes ENSRNOG00000000973 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000049512 ENTREZGENE
  ENSRNOT00000049512.7 UniProtKB/TrEMBL
InterPro DUF4601 UniProtKB/TrEMBL
KEGG Report rno:498129 UniProtKB/TrEMBL
NCBI Gene 498129 ENTREZGENE
PANTHER PTHR34828 UniProtKB/TrEMBL
  TESTIS-EXPRESSED PROTEIN 45 UniProtKB/TrEMBL
Pfam DUF4601 UniProtKB/TrEMBL
PhenoGen Saxo5 PhenoGen
RatGTEx ENSRNOG00000000973 RatGTEx
UniProt A6KQ04 ENTREZGENE, UniProtKB/TrEMBL
  D3Z9Q6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-05 Saxo5  stabilizer of axonemal microtubules 5  Tex45  testis expressed 45  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-03-27 Tex45  testis expressed 45  RGD1563425  similar to FLJ35784 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 RGD1563425  similar to FLJ35784 protein  LOC100362012  hypothetical protein LOC100362012  Data merged from RGD:2318968 1643240 APPROVED
2010-05-05 LOC100362012  hypothetical protein LOC100362012      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1563425  similar to FLJ35784 protein   RGD1563425_predicted  similar to FLJ35784 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563425_predicted  similar to FLJ35784 protein (predicted)  LOC498129  similar to FLJ35784 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498129  similar to FLJ35784 protein      Symbol and Name status set to provisional 70820 PROVISIONAL