Pilrb2l2 (paired immunoglobin like type 2 receptor beta 2 like 2) - Rat Genome Database

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Gene: Pilrb2l2 (paired immunoglobin like type 2 receptor beta 2 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Pilrb2l2
Name: paired immunoglobin like type 2 receptor beta 2 like 2
RGD ID: 1563400
Description: Predicted to be located in cell periphery and membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC102546487; LOC102553358; LOC360777; paired immunoglobulin-like type 2 receptor beta-2; RGD1563400; similar to paired immunoglobin-like type 2 receptor beta; uncharacterized LOC102546487; uncharacterized LOC102553358
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,956,263 - 22,971,611 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21218,566,841 - 18,580,286 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1218,566,837 - 18,582,202 (-)EnsemblmRatBN7.2
Rnor_6.01220,185,100 - 20,208,194 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,480,094 - 20,486,276 (-)Ensemblrn6Rnor6.0
Rnor_5.01222,239,253 - 22,247,676 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41218,574,807 - 18,582,256 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Cytogenetic Map12q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell periphery  (IEA)
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Pilrb2l2
172 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:81
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000074057
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)122013902826430640Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat

Markers in Region
BI275393  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map12265.0UniSTS
Cytogenetic Map12q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 10 49 118 53 56 37 86 37 277 154 11 107 68 69 19 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000074057   ⟹   ENSRNOP00000067454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1220,480,094 - 20,486,276 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094913   ⟹   ENSRNOP00000085959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,566,837 - 18,574,469 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098725   ⟹   ENSRNOP00000090856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,210,535 - 18,216,443 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102540   ⟹   ENSRNOP00000083501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,566,837 - 18,582,202 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119260   ⟹   ENSRNOP00000090991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,210,535 - 18,216,443 (-)Ensembl
RefSeq Acc Id: XM_039090026   ⟹   XP_038945954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,956,263 - 22,969,715 (-)NCBI
mRatBN7.21218,566,841 - 18,580,276 (-)NCBI
RefSeq Acc Id: XM_039090028   ⟹   XP_038945956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,956,263 - 22,969,717 (-)NCBI
mRatBN7.21218,566,841 - 18,580,277 (-)NCBI
RefSeq Acc Id: XM_039090031   ⟹   XP_038945959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,956,263 - 22,962,261 (-)NCBI
mRatBN7.21218,566,841 - 18,572,839 (-)NCBI
RefSeq Acc Id: XM_063271746   ⟹   XP_063127816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,956,263 - 22,971,611 (-)NCBI
RefSeq Acc Id: XM_063271747   ⟹   XP_063127817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,956,263 - 22,969,715 (-)NCBI
RefSeq Acc Id: XM_063271748   ⟹   XP_063127818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,956,263 - 22,969,717 (-)NCBI
RefSeq Acc Id: XM_063271749   ⟹   XP_063127819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,956,263 - 22,969,725 (-)NCBI
RefSeq Acc Id: XP_038945956   ⟸   XM_039090028
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXB5 (UniProtKB/TrEMBL),   A0A8I6A2R8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945954   ⟸   XM_039090026
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXB5 (UniProtKB/TrEMBL),   A0A8I6A2R8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945959   ⟸   XM_039090031
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000067454   ⟸   ENSRNOT00000074057
Ensembl Acc Id: ENSRNOP00000090991   ⟸   ENSRNOT00000119260
Ensembl Acc Id: ENSRNOP00000090856   ⟸   ENSRNOT00000098725
Ensembl Acc Id: ENSRNOP00000083501   ⟸   ENSRNOT00000102540
Ensembl Acc Id: ENSRNOP00000085959   ⟸   ENSRNOT00000094913
RefSeq Acc Id: XP_063127816   ⟸   XM_063271746
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXB5 (UniProtKB/TrEMBL),   A0A8I6A2R8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127819   ⟸   XM_063271749
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A2R8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127818   ⟸   XM_063271748
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXB5 (UniProtKB/TrEMBL),   A0A8I6A2R8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127817   ⟸   XM_063271747
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXB5 (UniProtKB/TrEMBL),   A0A8I6A2R8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RCW7-F1-model_v2 AlphaFold M0RCW7 1-211 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563400 AgrOrtholog
BioCyc Gene G2FUF-19740 BioCyc
Ensembl Genes ENSRNOG00000048881 Ensembl
  ENSRNOG00000066264 Ensembl
  ENSRNOG00000083768 UniProtKB/TrEMBL
  ENSRNOG00000090590 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000094913 ENTREZGENE
  ENSRNOT00000094913.2 UniProtKB/TrEMBL
  ENSRNOT00000102540.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Immunoregulatory_rcpt-like UniProtKB/TrEMBL
NCBI Gene 360777 ENTREZGENE
PANTHER PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR UniProtKB/TrEMBL
  PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR BETA-RELATED UniProtKB/TrEMBL
PhenoGen Pilrb2l2 PhenoGen
RatGTEx ENSRNOG00000048881 RatGTEx
  ENSRNOG00000066264 RatGTEx
  ENSRNOG00000083768 RatGTEx
  ENSRNOG00000090590 RatGTEx
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8I5ZXB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2R8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Pilrb2l2  paired immunoglobin like type 2 receptor beta 2 like 2  RGD1563400  similar to paired immunoglobin-like type 2 receptor beta  Symbol and Name Changed 1299863 APPROVED
2022-06-02 RGD1563400  similar to paired immunoglobin-like type 2 receptor beta  RGD1563400  similar to paired immunoglobin-like type 2 receptor beta  Data merged from RGD:149736363 737654 PROVISIONAL
2021-08-09 RGD1563400  similar to paired immunoglobin-like type 2 receptor beta      Symbol and Name status set to provisional 45752 PROVISIONAL
2021-03-09 RGD1563400  similar to paired immunoglobin-like type 2 receptor beta  LOC102546487  uncharacterized LOC102546487  Data merged from RGD:7657154 737654 PROVISIONAL
2015-07-29 RGD1563400  similar to paired immunoglobin-like type 2 receptor beta  LOC102553358  uncharacterized LOC102553358  Data merged from RGD:7504677 737654 PROVISIONAL
2013-12-18 LOC102546487  uncharacterized LOC102546487      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-12-17 LOC102553358  uncharacterized LOC102553358      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1563400  similar to paired immunoglobin-like type 2 receptor beta   RGD1563400_predicted  similar to paired immunoglobin-like type 2 receptor beta (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563400_predicted  similar to paired immunoglobin-like type 2 receptor beta (predicted)  LOC360777  similar to paired immunoglobin-like type 2 receptor beta  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC360777  similar to paired immunoglobin-like type 2 receptor beta      Symbol and Name status set to provisional 70820 PROVISIONAL