Ccsap (centriole, cilia and spindle-associated protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ccsap (centriole, cilia and spindle-associated protein) Rattus norvegicus
Analyze
Symbol: Ccsap
Name: centriole, cilia and spindle-associated protein
RGD ID: 1563235
Description: Predicted to enable microtubule binding activity. Predicted to be involved in mitotic spindle microtubule depolymerization and regulation of mitotic spindle assembly. Predicted to be located in centrosome; cilium; and mitotic spindle astral microtubule. Predicted to be active in axon; ciliary transition zone; and cytoskeleton. Orthologous to human CCSAP (centriole, cilia and spindle associated protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC307926; LOC307926; RGD1563235; similar to 1700054N08Rik protein; uncharacterized protein LOC307926
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,722,417 - 68,740,908 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21951,824,954 - 51,843,469 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,826,994 - 51,842,753 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,618,312 - 58,634,329 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01959,463,019 - 59,478,781 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01961,544,736 - 61,560,759 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,615,326 - 56,634,031 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,617,399 - 56,633,633 (-)Ensemblrn6Rnor6.0
Rnor_5.01967,325,673 - 67,344,357 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41954,023,536 - 54,039,295 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1951,202,808 - 51,218,570 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21399614   PMID:22493317   PMID:22871113   PMID:26562023  


Genomics

Comparative Map Data
Ccsap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,722,417 - 68,740,908 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21951,824,954 - 51,843,469 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,826,994 - 51,842,753 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,618,312 - 58,634,329 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01959,463,019 - 59,478,781 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01961,544,736 - 61,560,759 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,615,326 - 56,634,031 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,617,399 - 56,633,633 (-)Ensemblrn6Rnor6.0
Rnor_5.01967,325,673 - 67,344,357 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41954,023,536 - 54,039,295 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1951,202,808 - 51,218,570 (-)NCBICelera
Cytogenetic Map19q12NCBI
CCSAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381229,321,015 - 229,343,047 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1229,321,011 - 229,343,294 (-)Ensemblhg38GRCh38
GRCh371229,456,762 - 229,478,794 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361227,523,382 - 227,545,358 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1202,725,069 - 202,747,007 (-)NCBICelera
Cytogenetic Map1q42.13NCBI
HuRef1199,947,395 - 199,969,335 (-)NCBIHuRef
CHM1_11230,729,073 - 230,751,009 (-)NCBICHM1_1
T2T-CHM13v2.01228,699,674 - 228,721,751 (-)NCBIT2T-CHM13v2.0
Ccsap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398124,566,712 - 124,586,948 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8124,567,570 - 124,586,948 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388123,839,973 - 123,860,209 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,840,831 - 123,860,209 (-)Ensemblmm10GRCm38
MGSCv378126,364,744 - 126,384,109 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368126,726,917 - 126,746,752 (-)NCBIMGSCv36mm8
Celera8128,108,117 - 128,127,086 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map872.22NCBI
Ccsap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554928,685,667 - 8,700,306 (+)NCBIChiLan1.0ChiLan1.0
CCSAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2119,869,216 - 19,891,296 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1120,061,493 - 20,083,578 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01204,865,261 - 204,887,279 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11209,898,803 - 209,919,392 (-)NCBIPanPan1.1PanPan1.1panPan2
CCSAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.149,878,171 - 9,896,962 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl49,878,186 - 9,893,572 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha49,881,370 - 9,888,329 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.049,920,899 - 9,927,859 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.149,925,054 - 9,931,784 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0410,038,852 - 10,045,591 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0410,292,284 - 10,299,028 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ccsap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934444,082,957 - 44,110,725 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648420,271,834 - 20,275,880 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648420,271,834 - 20,277,945 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCSAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1460,445,574 - 60,464,599 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11460,445,052 - 60,465,761 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21465,286,260 - 65,305,987 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCSAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12566,593,506 - 66,611,462 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2566,589,906 - 66,610,999 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605568,435,894 - 68,458,209 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccsap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477519,694,087 - 19,713,650 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477519,693,987 - 19,715,937 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ccsap
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11743,385,037 - 43,402,588 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:878
Count of miRNA genes:322
Interacting mature miRNAs:418
Transcripts:ENSRNOT00000023911
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 163 91 90 59 92 59 6 354 191 11 142 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000023911   ⟹   ENSRNOP00000023911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1951,826,994 - 51,842,753 (-)Ensembl
Rnor_6.0 Ensembl1956,617,399 - 56,633,633 (-)Ensembl
RefSeq Acc Id: NM_001107441   ⟹   NP_001100911
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,724,457 - 68,740,216 (-)NCBI
mRatBN7.21951,826,994 - 51,842,753 (-)NCBI
Rnor_6.01956,617,366 - 56,633,125 (-)NCBI
Rnor_5.01967,325,673 - 67,344,357 (-)NCBI
RGSC_v3.41954,023,536 - 54,039,295 (-)RGD
Celera1951,202,808 - 51,218,570 (-)RGD
Sequence:
RefSeq Acc Id: XM_006255811   ⟹   XP_006255873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,722,417 - 68,740,908 (-)NCBI
mRatBN7.21951,824,954 - 51,843,469 (-)NCBI
Rnor_6.01956,615,326 - 56,634,031 (-)NCBI
Rnor_5.01967,325,673 - 67,344,357 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063278071   ⟹   XP_063134141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,722,417 - 68,740,903 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001100911 (Get FASTA)   NCBI Sequence Viewer  
  XP_006255873 (Get FASTA)   NCBI Sequence Viewer  
  XP_063134141 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96713 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000104610.1
  ENSRNOP00000109988.1
RefSeq Acc Id: NP_001100911   ⟸   NM_001107441
- UniProtKB: D3ZZM9 (UniProtKB/TrEMBL),   A6KIZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255873   ⟸   XM_006255811
- Peptide Label: isoform X1
- UniProtKB: D3ZZM9 (UniProtKB/TrEMBL),   A6KIZ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023911   ⟸   ENSRNOT00000023911
RefSeq Acc Id: XP_063134141   ⟸   XM_063278071
- Peptide Label: isoform X1
- UniProtKB: A6KIZ1 (UniProtKB/TrEMBL),   D3ZZM9 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZM9-F1-model_v2 AlphaFold D3ZZM9 1-252 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563235 AgrOrtholog
BioCyc Gene G2FUF-5266 BioCyc
Ensembl Genes ENSRNOG00000017690 Ensembl
  ENSRNOG00000074620 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000138739.1 UniProtKB/TrEMBL
  ENSRNOT00000143377.1 UniProtKB/TrEMBL
InterPro CSAP UniProtKB/TrEMBL
KEGG Report rno:307926 UniProtKB/TrEMBL
NCBI Gene 307926 ENTREZGENE
PANTHER CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN UniProtKB/TrEMBL
  PTHR31022 UniProtKB/TrEMBL
Pfam CCSAP UniProtKB/TrEMBL
PhenoGen Ccsap PhenoGen
RatGTEx ENSRNOG00000017690 RatGTEx
  ENSRNOG00000074620 RatGTEx
UniProt A0ABK0LGN9_RAT UniProtKB/TrEMBL
  A0ABK0LRN8_RAT UniProtKB/TrEMBL
  A6KIZ1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZM9 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-12 Ccsap  centriole, cilia and spindle-associated protein  RGD1563235  similar to 1700054N08Rik protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1563235  similar to 1700054N08Rik protein   RGD1563235_predicted  similar to 1700054N08Rik protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563235_predicted  similar to 1700054N08Rik protein (predicted)  LOC307926  similar to 1700054N08Rik protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC307926  similar to 1700054N08Rik protein      Symbol and Name status set to provisional 70820 PROVISIONAL