Advanced Search (OLGA)

Gene: Gspt2 (G1 to S phase transition 2) Rattus norvegicus

Analyze

Symbol:

Gspt2

Name:

G1 to S phase transition 2

RGD ID:

1563213

Description:

Predicted to enable GTPase activity and translation release factor activity. Predicted to be involved in translational termination. Predicted to be located in cytosol. Predicted to be part of translation release factor complex. Orthologous to human GSPT2 (G1 to S phase transition 2); PARTICIPATES IN mRNA decay pathway; INTERACTS WITH all-trans-retinoic acid; bisphenol A; dibutyl phthalate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

eukaryotic peptide chain release factor GTP-binding subunit ERF3B; LOC501582; RGD1563213; similar to peptide chain release factor 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GSPT2 (G1 to S phase transition 2)	HGNC	Ensembl, HomoloGene, OMA, Panther
Mus musculus (house mouse):	Gspt2 (G1 to S phase transition 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gspt2 (G1 to S phase transition 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GSPT2 (G1 to S phase transition 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GSPT2 (G1 to S phase transition 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gspt2 (G1 to S phase transition 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GSPT2 (G1 to S phase transition 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GSPT2 (G1 to S phase transition 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gspt2 (G1 to S phase transition 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GSPT1 (G1 to S phase transition 1)	HGNC	OrthoDB
Homo sapiens (human):	AIF1 (allograft inflammatory factor 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	GSPT2 (G1 to S phase transition 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gspt2 (G1 to S phase transition 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gspt1 (G1 to S phase transition 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gspt1 (G1 to S phase transition 1)	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	gspt1l (G1 to S phase transition 1, like)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	erfa-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SUP35	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	eRF3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gspt1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	63,582,649 - 63,597,467 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	63,582,690 - 63,700,401 (+)	Ensembl				GRCr8
mRatBN7.2	X	59,587,237 - 59,589,758 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	59,587,276 - 59,594,162 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	61,041,357 - 61,043,878 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	64,542,488 - 64,545,009 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	62,122,571 - 62,125,092 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	63,959,131 - 63,961,652 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	63,954,727 - 63,961,613 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	64,865,560 - 64,868,081 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	82,269,814 - 82,272,335 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	60,014,268 - 60,016,789 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2-methylcholine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP)

arsenite(3-) (ISO)

arsenous acid (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

choline (ISO)

decabromodiphenyl ether (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP,ISO)

diuron (EXP)

dorsomorphin (ISO)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

formaldehyde (ISO)

genistein (EXP)

GSK-J4 (ISO)

inulin (ISO)

iron dichloride (ISO)

ivermectin (ISO)

L-methionine (ISO)

maneb (ISO)

manganese(II) chloride (EXP)

N-methyl-4-phenylpyridinium (EXP)

N-nitrosodiethylamine (ISO)

nickel sulfate (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

streptozocin (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (IEA)

translation (IBA,IEA)

translational termination (ISO)

Cellular Component

cytosol (IEA,ISO)

translation release factor complex (IBA)

Molecular Function

GTP binding (IEA)

GTPase activity (IBA,IEA,ISO)

hydrolase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

translation release factor activity (IBA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mRNA decay pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Gspt2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	63,582,649 - 63,597,467 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	63,582,690 - 63,700,401 (+)	Ensembl				GRCr8
mRatBN7.2	X	59,587,237 - 59,589,758 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	59,587,276 - 59,594,162 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	61,041,357 - 61,043,878 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	64,542,488 - 64,545,009 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	62,122,571 - 62,125,092 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	63,959,131 - 63,961,652 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	63,954,727 - 63,961,613 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	64,865,560 - 64,868,081 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	82,269,814 - 82,272,335 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	60,014,268 - 60,016,789 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

GSPT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	51,743,442 - 51,746,232 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	51,743,442 - 51,746,232 (+)	Ensembl			hg38	GRCh38
GRCh37	X	51,486,538 - 51,489,328 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	51,503,267 - 51,505,769 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	51,319,562 - 51,322,065	NCBI
Celera	X	56,241,885 - 56,244,732 (-)	NCBI		Celera
Cytogenetic Map	X	p11.22	NCBI
HuRef	X	48,925,476 - 48,928,323 (+)	NCBI		HuRef
CHM1_1	X	51,560,357 - 51,563,204 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	51,015,099 - 51,017,889 (+)	NCBI		T2T-CHM13v2.0

Gspt2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	93,679,675 - 93,682,168 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	93,679,675 - 93,686,850 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	94,636,069 - 94,638,562 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	94,636,069 - 94,643,244 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	91,881,408 - 91,883,901 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	90,888,788 - 90,891,281 (+)	NCBI		MGSCv36	mm8
Celera	X	81,563,638 - 81,566,131 (+)	NCBI		Celera
Cytogenetic Map	X	C3	NCBI
cM Map	X	41.63	NCBI

Gspt2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955543	2,879,974 - 2,882,473 (-)	NCBI	ChiLan1.0	ChiLan1.0

GSPT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	53,129,537 - 53,135,250 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	53,133,134 - 53,138,840 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	43,939,890 - 43,942,733 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	51,833,651 - 51,836,492 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

GSPT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	44,319,042 - 44,321,615 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	44,319,314 - 44,321,197 (+)	Ensembl			canFam3	CanFam3.1
ROS_Cfam_1.0	X	44,445,193 - 44,447,762 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	44,445,231 - 44,447,751 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	44,275,384 - 44,277,953 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	44,445,664 - 44,448,233 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	44,674,822 - 44,677,391 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gspt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	37,221,623 - 37,224,163 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936909	436,018 - 438,651 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936909	436,004 - 438,818 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GSPT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	45,193,338 - 45,195,901 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	45,193,336 - 45,195,939 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	50,566,493 - 50,569,069 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GSPT2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	48,463,262 - 48,466,090 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	48,463,500 - 48,465,386 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666086	2,192,722 - 2,195,568 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gspt2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624893	3,730,845 - 3,733,258 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624893	3,730,830 - 3,733,374 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Gspt2
37 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	31
Count of miRNA genes:	28
Interacting mature miRNAs:	31
Transcripts:	ENSRNOT00000071762
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	45182909	117740458	Rat
70221	Bp56	Blood pressure QTL 56	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	61035856	67175160	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	44930883	89930883	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	148	91	90	59	32	59	6	295	132	11	127	80	92	31	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000071762 ⟹ ENSRNOP00000068098

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	63,582,801 - 63,657,822 (+)	Ensembl
mRatBN7.2 Ensembl	X	59,587,304 - 59,592,138 (+)	Ensembl
Rnor_6.0 Ensembl	X	63,959,434 - 63,961,527 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076205 ⟹ ENSRNOP00000068496

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	63,582,762 - 63,622,683 (+)	Ensembl
mRatBN7.2 Ensembl	X	59,587,276 - 59,594,162 (+)	Ensembl
Rnor_6.0 Ensembl	X	63,954,727 - 63,961,613 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000129078 ⟹ ENSRNOP00000104928

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	63,582,739 - 63,700,401 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000136165 ⟹ ENSRNOP00000109864

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	63,582,690 - 63,659,907 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000145984 ⟹ ENSRNOP00000107701

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	63,582,743 - 63,611,229 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000152489 ⟹ ENSRNOP00000106356

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	63,582,770 - 63,668,862 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000165366 ⟹ ENSRNOP00000108574

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	63,582,808 - 63,585,094 (+)	Ensembl

RefSeq Acc Id:

NM_001109319 ⟹ NP_001102789

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	63,582,745 - 63,585,266 (+)	NCBI
mRatBN7.2	X	59,587,237 - 59,589,758 (+)	NCBI
Rnor_6.0	X	63,959,131 - 63,961,652 (-)	NCBI
Rnor_5.0	X	64,865,560 - 64,868,081 (-)	NCBI
RGSC_v3.4	X	82,269,814 - 82,272,335 (+)	RGD
Celera	X	60,014,268 - 60,016,789 (+)	RGD

Sequence:

show sequence

GGAGATTCGCTCACACACTGGAGCTGAGCCTTGAGCGGCCATATCTGCCGCCGCCGCAGCTGTG
AATGCAGCATCTGCGCTTAGCTGCCTTCGCGCTGCTAAGGTTCGCGTCGCTCGCCCGTGGTCCG
TGGCCGTTCCTGCCTTACTACCACCGGTAGAACCCTCTCCTTCTGACCTGCCTACCTCGCTCCT
TCTCCGCCGCACCCCGGCTGCTCACACCATGGATCTCGGCAGCAGCAGCGACTCGGCTCCCGAC
TGCTGGGATCAGGTGGACATGGAAGCCCCGGGTTCGGCTCCGAGCGGGGATGAAATCGCCCCCG
CAGCCACGGCAGCGGCTGAGGCCGCGGAAGCCGAGGCCCAGCGCAGGCATCTCAGCTTGGCCTT
CAGCAGTCAGCTCAACATCAACGCCAAACCTTTCGTGCCTAGCGTAAGCGCAGCGGAGTTCGTG
CCGTCCTTCCTGCCCGGATCGGCCCAGCTGCCCGCCCCCACAGCCTCCAGCTGCGACGAAACCT
GCATCGGTGGCGCCGCGGAGCCTCAAGGTAAAAGGATGGAATGGGGAGCACCTGTGGAACCTTC
CAAAGATGGACCTTTAGTGTCGTGGGAGGGTTCCAATTCAGCTGTTACCATGGAACTTTCAGAA
CCTGTTGTAGAAAATGGAGAGGTGGAGATGGCCCTGGAAGAATCGTGGGAGCTTAAAGAAGTAA
GTGAAGCAGCGCCTGAGGGTTCTTTGGGAGATGTAGGGCCCCCAGAAGAGAGTGGCAAGGAAGT
GATGGAGGAGAAAGAGGAAATAAGGAAATCAAAATCTGTGGTCAGACCATCAGGTGCTCCTAAG
AAAGAACACGTAAATGTGGTGTTCATTGGGCATGTAGATGCCGGCAAGTCAACCATTGGAGGAC
AGATAATGTTTTTGACAGGAATGGTTGACAGAAGGACACTTGAGAAATACGAACGAGAAGCTAA
GGAGAAGAATAGAGAGACCTGGTACTTGTCCTGGGCCTTAGATACAAACCAGGAAGAACGAGAC
AAGGGTAAAACAGTGGAAGTGGGCCGTGCATATTTTGAAACAGAAAAGAAACATTTCACAATCT
TAGATGCCCCTGGCCACAAGAGTTTTGTCCCAAATATGATTGGTGGTGCTTCTCAAGCTGATTT
AGCCGTGCTGGTCATCTCTGCCAGGAAAGGAGAATTTGAAACTGGGTTTGAAAAAGGTGGACAG
ACAAGAGAGCATGCAATGTTGGCCAAAACAGCAGGGGTGAAATACTTAATAGTGCTGATTAATA
AGATGGATGATCCCACAGTAGATTGGAGCAGTGAGCGATACGAAGAATGTAAAGAGAAACTGGT
GCCCTTTTTGAAAAAAGTTGGATTCAGTCCAAAAAAGGACATTCACTTTATGCCCTGCTCAGGA
CTGACTGGAGCAAATATTAAAGAGCAATCCGATTTCTGTCCCTGGTACACTGGGTTACCATTTA
TTCCATATTTGGATAGTTTGCCAAACTTCAACAGATCAATTGATGGGCCAATTAGGTTGCCCAT
TGTGGATAAGTACAAGGATATGGGCACTGTGGTCCTGGGAAAGCTGGAATCAGGGTCCATTTTT
AAAGGCCAGCAGCTTGTAATGATGCCGAACAAGCACAGTGTGGAAGTTCTAGGAATAGTTTCCG
ATGATGCTGAGACTGATTTTGTAGCTCCAGGTGAAAACCTCAAAATCAGACTGAAAGGAATCGA
AGAAGAAGAGATTCTTCCGGGCTTCATACTTTGTGAACCCAATAATCTCTGCCATTCTGGACGC
ACATTTGATGTTCAGATAGTGATCATTGAGCACAAGTCTATCATCTGCCCAGGTTACAATGCGG
TGCTTCACATTCATACGTGTATAGAGGAGGTCGAGATAACAGCCTTGATCTCCTTGGTAGACAA
AAAGTCAGGAGAAAAAAGCAAGACACGGCCCCGCTTTGTGAAGCAAGATCAAGTGTGCATTGCC
CGGTTAAGGACAGCAGGAACTATCTGCCTGGAGACGTTTAAAGATTTTCCTCAGATGGGTCGTT
TTACTTTAAGAGATGAGGGAAAGACCATCGCGATTGGAAAAGTTCTGAAGCTGGTCCCAGAGAA
GGACTAAGCAATCCCATTTGATGCCTCTGCACACCGTAATGTGCGAAAGAAAGATTGTCTGCAA
TCTACTGCCCATTCACAGAACTGTGCCCATGTTTTGCAGAGAAATTTCACAGCGAAAATCCACG
TTTTGTCAGCTTTCTCATGTTGAGATCTCAGTCGTGTCACTCCTGAATGCATACTCCAGTTTCC
TCCCTCTATACCACTCTGCTTCCTTGGACAAATCAGTAATAGCTTTGTAAGTGATGTGTATGTA
ATTGCCTACAATACTAAAAATAATATATTTTAAATTTTCCATTTCCCTTGGGGATCGATCTTTA
GACATCCTTTGTTCTGTGCAGAACAATCAGTATGTGTATATGTTGATGAAGACCACTGACGTGT
AAATAAAACGTTCTGGTTGAAACTGC

hide sequence

RefSeq Acc Id:

XM_063280250 ⟹ XP_063136320

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	63,582,649 - 63,595,194 (+)	NCBI

RefSeq Acc Id:

XM_063280251 ⟹ XP_063136321

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	63,582,649 - 63,597,467 (+)	NCBI

RefSeq Acc Id:

XM_063280252 ⟹ XP_063136322

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	63,582,649 - 63,597,467 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102789	(Get FASTA)	NCBI Sequence Viewer
	XP_063136320	(Get FASTA)	NCBI Sequence Viewer
	XP_063136321	(Get FASTA)	NCBI Sequence Viewer
	XP_063136322	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL95997	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068098.1
	ENSRNOP00000068496
	ENSRNOP00000068496.2
	ENSRNOP00000104928.1
	ENSRNOP00000106356
	ENSRNOP00000106356.1
	ENSRNOP00000107701.1
	ENSRNOP00000108574.1
	ENSRNOP00000109864.1

RefSeq Acc Id:

NP_001102789 ⟸ NM_001109319

- UniProtKB:

A0A096MJE3 (UniProtKB/TrEMBL), A6IQ16 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDLGSSSDSAPDCWDQVDMEAPGSAPSGDEIAPAATAAAEAAEAEAQRRHLSLAFSSQLNINAK
PFVPSVSAAEFVPSFLPGSAQLPAPTASSCDETCIGGAAEPQGKRMEWGAPVEPSKDGPLVSWE
GSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAAPEGSLGDVGPPEESGKEVMEEKEEIRK
SKSVVRPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYL
SWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARK
GEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFS
PKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGT
VVLGKLESGSIFKGQQLVMMPNKHSVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFI
LCEPNNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTR
PRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD

hide sequence

Ensembl Acc Id:

ENSRNOP00000068098 ⟸ ENSRNOT00000071762

Ensembl Acc Id:

ENSRNOP00000068496 ⟸ ENSRNOT00000076205

RefSeq Acc Id:	XP_063136321 ⟸ XM_063280251
- Peptide Label:	isoform X1
- UniProtKB:	A0A096MJE3 (UniProtKB/TrEMBL), A6IQ16 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063136322 ⟸ XM_063280252
- Peptide Label:	isoform X1
- UniProtKB:	A0A096MJE3 (UniProtKB/TrEMBL), A6IQ16 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063136320 ⟸ XM_063280250
- Peptide Label:	isoform X1
- UniProtKB:	A0A096MJE3 (UniProtKB/TrEMBL), A6IQ16 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000109864 ⟸ ENSRNOT00000136165

Ensembl Acc Id:

ENSRNOP00000104928 ⟸ ENSRNOT00000129078

Ensembl Acc Id:

ENSRNOP00000107701 ⟸ ENSRNOT00000145984

Ensembl Acc Id:

ENSRNOP00000108574 ⟸ ENSRNOT00000165366

Ensembl Acc Id:

ENSRNOP00000106356 ⟸ ENSRNOT00000152489

Protein Domains

tr-type G

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A096MJE3-F1-model_v2	AlphaFold	A0A096MJE3	1-632	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701844

Promoter ID:

EPDNEW_R12368

Type:

single initiation site

Name:

Gspt2_1

Description:

G1 to S phase transition 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	63,961,612 - 63,961,672	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563213	AgrOrtholog
BioCyc Gene	G2FUF-2220	BioCyc
Ensembl Genes	ENSRNOG00000048817	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000071762.4	UniProtKB/TrEMBL
	ENSRNOT00000076205	ENTREZGENE
	ENSRNOT00000076205.3	UniProtKB/TrEMBL
	ENSRNOT00000129078.1	UniProtKB/TrEMBL
	ENSRNOT00000136165.1	UniProtKB/TrEMBL
	ENSRNOT00000145984.1	UniProtKB/TrEMBL
	ENSRNOT00000152489	ENTREZGENE
	ENSRNOT00000152489.1	UniProtKB/TrEMBL
	ENSRNOT00000165366.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
	Translation factors	UniProtKB/TrEMBL
InterPro	Ataxin-2_C	UniProtKB/TrEMBL
	EF_GTP-bd_dom	UniProtKB/TrEMBL
	G_TR_CS	UniProtKB/TrEMBL
	GTP-eEF1A_C	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	TRAFAC_GTPase_members	UniProtKB/TrEMBL
	Transl_B-barrel	UniProtKB/TrEMBL
	Transl_elong_EF1A/Init_IF2_C	UniProtKB/TrEMBL
	Transl_elong_EFTu/EF1A_2	UniProtKB/TrEMBL
KEGG Report	rno:501582	UniProtKB/TrEMBL
NCBI Gene	501582	ENTREZGENE
PANTHER	TRANSLATION FACTOR	UniProtKB/TrEMBL
Pfam	GTP-eEF1A_C	UniProtKB/TrEMBL
	GTP_EFTU	UniProtKB/TrEMBL
	GTP_EFTU_D2	UniProtKB/TrEMBL
	PAM2	UniProtKB/TrEMBL
PhenoGen	Gspt2	PhenoGen
PRINTS	ELONGATNFCT	UniProtKB/TrEMBL
PROSITE	EFACTOR_GTP	UniProtKB/TrEMBL
	G_TR_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000048817	RatGTEx
Superfamily-SCOP	SSF50447	UniProtKB/TrEMBL
	SSF50465	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A0A096MJE3	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0M2B0_RAT	UniProtKB/TrEMBL
	A6IQ16	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A096MKF6	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Gspt2	G1 to S phase transition 2	RGD1563213_predicted	similar to peptide chain release factor 3 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1563213_predicted	similar to peptide chain release factor 3 (predicted)	LOC501582	similar to peptide chain release factor 3	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC501582	similar to peptide chain release factor 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)