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Gene: Qrich2 (glutamine rich 2) Rattus norvegicus

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Symbol:

Qrich2

Name:

glutamine rich 2

RGD ID:

1562974

Description:

Predicted to be involved in cell projection assembly; flagellated sperm motility; and negative regulation of ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be active in sperm flagellum. Human ortholog(s) of this gene implicated in spermatogenic failure 35. Orthologous to human QRICH2 (glutamine rich 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

glutamine-rich protein 2; glutamine-rich protein 2-like; LOC102550872; LOC120095214; LOC120095347; LOC501747; RGD1562974; similar to hypothetical protein DKFZp434P0316

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	QRICH2 (glutamine rich 2)	HGNC	Ensembl, HomoloGene, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Qrich2 (glutamine rich 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Qrich2 (glutamine rich 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	QRICH2 (glutamine rich 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	QRICH2 (glutamine rich 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Qrich2 (glutamine rich 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	QRICH2 (glutamine rich 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	QRICH2 (glutamine rich 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Qrich2 (glutamine rich 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TSSK1B (testis specific serine kinase 1B)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	QRICH2 (glutamine rich 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Qrich2 (glutamine rich 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG10869	Alliance	DIOPT (OrthoInspector\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	102,168,103 - 102,196,497 (-)	NCBI		GRCr8
mRatBN7.2	10	101,669,240 - 101,697,643 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	101,669,224 - 101,697,656 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	10	105,397,470 - 105,422,811 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	105,399,814 - 105,412,627 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	105,061,225 - 105,084,356 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	106,549,913 - 106,578,744 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	100,240,010 - 100,270,017 (-)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Qrich2	Rat	spermatogenic failure 35		ISO	QRICH2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:25741868 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Qrich2	Rat	spermatogenic failure 35		ISO	QRICH2 (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Qrich2	Rat	2,2',5,5'-tetrachlorobiphenyl	decreases expression	ISO	QRICH2 (Homo sapiens)	6480464	2 more ...	CTD	PMID:36804509
Qrich2	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of QRICH2 mRNA	CTD	PMID:33387578
Qrich2	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	QRICH2 (Homo sapiens)	6480464	bisphenol S results in decreased expression of QRICH2 mRNA	CTD	PMID:30616060
Qrich2	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of QRICH2 mRNA	CTD	PMID:30047161
Qrich2	Rat	aflatoxin B1	increases methylation	ISO	QRICH2 (Homo sapiens)	6480464	Aflatoxin B1 results in increased methylation of QRICH2 intron	CTD	PMID:30157460
Qrich2	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of QRICH2 mRNA	CTD	PMID:35163327
Qrich2	Rat	amitrole	increases expression	EXP		6480464	Amitrole results in increased expression of QRICH2 mRNA	CTD	PMID:30047161
Qrich2	Rat	aristolochic acid A	increases expression	ISO	QRICH2 (Homo sapiens)	6480464	aristolochic acid I results in increased expression of QRICH2 mRNA	CTD	PMID:33212167
Qrich2	Rat	arsane	affects methylation	ISO	QRICH2 (Homo sapiens)	6480464	Arsenic affects the methylation of QRICH2 gene	CTD	PMID:25304211
Qrich2	Rat	arsenic atom	affects methylation	ISO	QRICH2 (Homo sapiens)	6480464	Arsenic affects the methylation of QRICH2 gene	CTD	PMID:25304211
Qrich2	Rat	benzo[a]pyrene	affects methylation	ISO	QRICH2 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of QRICH2 3' UTR	CTD	PMID:27901495
Qrich2	Rat	benzo[e]pyrene	affects methylation	ISO	QRICH2 (Homo sapiens)	6480464	benzo(e)pyrene affects the methylation of QRICH2 intron	CTD	PMID:30157460
Qrich2	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	Qrich2 (Mus musculus)	6480464	Diethylhexyl Phthalate results in increased expression of QRICH2 mRNA	CTD	PMID:34319233
Qrich2	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of QRICH2 mRNA	CTD	PMID:25181051
Qrich2	Rat	bisphenol A	decreases methylation	ISO	Qrich2 (Mus musculus)	6480464	bisphenol A results in decreased methylation of QRICH2 promoter	CTD	PMID:27312807
Qrich2	Rat	cadmium dichloride	increases expression	ISO	QRICH2 (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of QRICH2 mRNA	CTD	PMID:38568856
Qrich2	Rat	CGP 52608	multiple interactions	ISO	QRICH2 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to QRICH2 gene]	CTD	PMID:28238834
Qrich2	Rat	cisplatin	decreases expression	ISO	QRICH2 (Homo sapiens)	6480464	Cisplatin results in decreased expression of QRICH2 mRNA	CTD	PMID:27392435
Qrich2	Rat	cisplatin	multiple interactions	ISO	QRICH2 (Homo sapiens)	6480464	[Cisplatin co-treated with jinfukang] results in decreased expression of QRICH2 mRNA	CTD	PMID:27392435
Qrich2	Rat	Cuprizon	increases expression	EXP		6480464	Cuprizone results in increased expression of QRICH2 mRNA	CTD	PMID:26577399
Qrich2	Rat	decabromodiphenyl ether	decreases expression	EXP		6480464	decabromobiphenyl ether results in decreased expression of QRICH2 mRNA	CTD	PMID:23640034
Qrich2	Rat	fenvalerate	increases expression	EXP		6480464	fenvalerate results in increased expression of QRICH2 mRNA	CTD	PMID:30307764
Qrich2	Rat	methapyrilene	affects methylation	ISO	QRICH2 (Homo sapiens)	6480464	Methapyrilene affects the methylation of QRICH2 intron	CTD	PMID:30157460
Qrich2	Rat	methimazole	increases expression	EXP		6480464	Methimazole results in increased expression of QRICH2 mRNA	CTD	PMID:30047161
Qrich2	Rat	mono(2-ethylhexyl) phthalate	increases expression	ISO	Qrich2 (Mus musculus)	6480464	mono-(2-ethylhexyl)phthalate results in increased expression of QRICH2 mRNA	CTD	PMID:22401849
Qrich2	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of QRICH2 mRNA	CTD	PMID:35163327
Qrich2	Rat	quercetin	increases expression	ISO	QRICH2 (Homo sapiens)	6480464	Quercetin results in increased expression of QRICH2 mRNA	CTD	PMID:21632981
Qrich2	Rat	rotenone	decreases expression	ISO	QRICH2 (Homo sapiens)	6480464	Rotenone results in decreased expression of QRICH2 mRNA	CTD	PMID:29955902
Qrich2	Rat	sodium arsenite	decreases expression	ISO	QRICH2 (Homo sapiens)	6480464	sodium arsenite results in decreased expression of QRICH2 mRNA	CTD	PMID:34032870
Qrich2	Rat	sodium dichromate	affects expression	EXP		6480464	sodium bichromate affects the expression of QRICH2 mRNA	CTD	PMID:22110744
Qrich2	Rat	sulforaphane	increases expression	ISO	QRICH2 (Homo sapiens)	6480464	sulforaphane results in increased expression of QRICH2 mRNA	CTD	PMID:31838189
Qrich2	Rat	thiram	increases expression	ISO	QRICH2 (Homo sapiens)	6480464	Thiram results in increased expression of QRICH2 mRNA	CTD	PMID:38568856
Qrich2	Rat	trichloroethene	increases expression	EXP		6480464	Trichloroethylene results in increased expression of QRICH2 mRNA	CTD	PMID:33387578
Qrich2	Rat	triptonide	increases expression	ISO	Qrich2 (Mus musculus)	6480464	triptonide results in increased expression of QRICH2 mRNA	CTD	PMID:33045310
Qrich2	Rat	urethane	increases expression	ISO	QRICH2 (Homo sapiens)	6480464	Urethane results in increased expression of QRICH2 mRNA	CTD	PMID:28818685
Qrich2	Rat	valproic acid	increases methylation	ISO	QRICH2 (Homo sapiens)	6480464	Valproic Acid results in increased methylation of QRICH2 gene	CTD	PMID:29154799

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Qrich2	Rat	cell projection assembly	involved_in	ISO	QRICH2 (Homo sapiens)	1624291	PMID:30683861	RGD	PMID:30683861
Qrich2	Rat	cell projection assembly	involved_in	IBA	MGI:2684912 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Qrich2	Rat	cell projection assembly	involved_in	ISO	Qrich2 (Mus musculus)	1624291	PMID:30683861	RGD	PMID:30683861
Qrich2	Rat	flagellated sperm motility	involved_in	ISO	Qrich2 (Mus musculus)	1624291	PMID:30683861	RGD	PMID:30683861
Qrich2	Rat	flagellated sperm motility	involved_in	IBA	MGI:2684912 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Qrich2	Rat	flagellated sperm motility	involved_in	ISO	QRICH2 (Homo sapiens)	1624291	PMID:30683861	RGD	PMID:30683861
Qrich2	Rat	negative regulation of ubiquitin-dependent protein catabolic process	involved_in	ISO	Qrich2 (Mus musculus)	1624291	PMID:30683861	RGD	PMID:30683861
Qrich2	Rat	negative regulation of ubiquitin-dependent protein catabolic process	involved_in	ISO	QRICH2 (Homo sapiens)	1624291	PMID:30683861	RGD	PMID:30683861

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Qrich2	Rat	cytoplasm	located_in	ISO	Qrich2 (Mus musculus)	1624291	PMID:30683861	RGD	PMID:30683861
Qrich2	Rat	nucleus	located_in	ISO	Qrich2 (Mus musculus)	1624291	PMID:30683861	RGD	PMID:30683861
Qrich2	Rat	sperm flagellum	located_in	ISO	Qrich2 (Mus musculus)	1624291	PMID:30683861	RGD	PMID:30683861
Qrich2	Rat	sperm flagellum	is_active_in	IBA	MGI:2684912 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Qrich2	Rat	sperm flagellum	located_in	ISO	QRICH2 (Homo sapiens)	1624291	PMID:30683861	RGD	PMID:30683861

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Qrich2	Rat	protein binding	enables	ISO	QRICH2 (Homo sapiens)	1624291	UniProtKB:O75969 more ...	RGD	PMID:30683861

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:16751776	PMID:30683861

Qrich2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	102,168,103 - 102,196,497 (-)	NCBI		GRCr8
mRatBN7.2	10	101,669,240 - 101,697,643 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	101,669,224 - 101,697,656 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	10	105,397,470 - 105,422,811 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	105,399,814 - 105,412,627 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	105,061,225 - 105,084,356 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	106,549,913 - 106,578,744 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	100,240,010 - 100,270,017 (-)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

QRICH2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	76,274,049 - 76,310,964 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	76,274,049 - 76,308,276 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	74,270,130 - 74,304,357 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	71,781,725 - 71,815,356 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	70,864,059 - 70,897,674 (-)	NCBI		Celera
Cytogenetic Map	17	q25.1	NCBI
HuRef	17	69,698,583 - 69,732,284 (-)	NCBI		HuRef
CHM1_1	17	74,335,030 - 74,368,659 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	77,170,605 - 77,207,519 (-)	NCBI		T2T-CHM13v2.0

Qrich2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	116,332,149 - 116,357,092 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	116,332,151 - 116,357,067 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	116,441,323 - 116,466,266 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	116,441,325 - 116,466,241 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	116,302,639 - 116,315,661 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	116,257,415 - 116,270,437 (-)	NCBI		MGSCv36	mm8
Celera	11	128,209,559 - 128,223,460 (-)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	81.3	NCBI

Qrich2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955506	5,990,070 - 6,015,808 (+)	NCBI	ChiLan1.0	ChiLan1.0

QRICH2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	92,314,174 - 92,351,636 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	97,141,692 - 97,176,848 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	70,222,033 - 70,256,747 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	75,774,464 - 75,790,954 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	75,774,651 - 75,807,651 (-)	Ensembl	panpan1.1		panPan2

QRICH2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	4,395,501 - 4,408,302 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	4,374,650 - 4,408,299 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	5,054,684 - 5,088,921 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	5,044,456 - 5,078,581 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	9	5,084,679 - 5,118,695 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	5,194,510 - 5,228,153 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	5,254,228 - 5,288,313 (+)	NCBI		UU_Cfam_GSD_1.0

Qrich2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	4,987,710 - 5,027,289 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936594	1,383,332 - 1,423,961 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

QRICH2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	5,176,926 - 5,199,272 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	5,174,531 - 5,203,797 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	5,078,319 - 5,104,527 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

QRICH2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	45,370,569 - 45,407,297 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666077	16,114,356 - 16,152,312 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Qrich2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	6,151,558 - 6,175,078 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	6,152,552 - 6,175,351 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Qrich2
93 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	104
Count of miRNA genes:	51
Interacting mature miRNAs:	52
Transcripts:	ENSRNOT00000034817, ENSRNOT00000072644
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354641	Bvd2	Brain ventricular dilatation QTL 2	6.36	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	10	93223816	107057807	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63221094	107211142	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	57576521	102576521	Rat
1579915	Bp280	Blood pressure QTL 280		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	90404397	107211142	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	72224939	107211142	Rat
1302404	Cia27	Collagen induced arthritis QTL 27	2.6	0.0045	joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	10	76452683	107211142	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	82685200	107211142	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
10450493	Bp382	Blood pressure QTL 382		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	94759759	107211142	Rat
1578672	Bmd16	Bone mineral density QTL 16	6.2		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	96703043	107057807	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62057807	107057807	Rat
2293646	Bss25	Bone structure and strength QTL 25	10.96	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	10	69738412	107211142	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
2300172	Bmd57	Bone mineral density QTL 57	9.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	10	69738412	107211142	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72224939	107211142	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62057807	107057807	Rat
61363	Oia3	Oil induced arthritis QTL 3		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87307617	107211142	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
724530	Bp149	Blood pressure QTL 149		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	90627439	107211142	Rat
1300137	Bp186	Blood pressure QTL 186	3.57		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	10	90627439	107057807	Rat
2293663	Bss33	Bone structure and strength QTL 33	9.34	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	10	69738412	107211142	Rat
1578663	Bss18	Bone structure and strength QTL 18	3.6		femur width (VT:1000666)	femoral neck width (CMO:0001695)	10	96703043	107057807	Rat
7387312	Bw125	Body weight QTL 125	3	0.0047	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight (CMO:0000356)	10	64890616	107211142	Rat
2312672	Insul15	Insulin level QTL 15		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	10	57134272	102134272	Rat
12880384	Cm107	Cardiac mass QTL 107		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)		90404397	107211142	Rat
12880385	Cm108	Cardiac mass QTL 108		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)		90404397	107211142	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	66978955	107211142	Rat
2303589	Bw87	Body weight QTL 87	2		body mass (VT:0001259)	body weight (CMO:0000012)	10	81285008	107211142	Rat
12880396	Am13	Aortic mass QTL 13		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	90404397	107211142	Rat
12880398	Kidm67	Kidney mass QTL 67		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	90404397	107211142	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	66978955	107211142	Rat
12880395	Cm109	Cardiac mass QTL 109		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	10	90404397	107211142	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68420376	107211142	Rat
634320	Niddm49	Non-insulin dependent diabetes mellitus QTL 49	4.41		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	10	88539139	107211142	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
10450498	Bp384	Blood pressure QTL 384		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	67750049	107211142	Rat
4889492	Pancm2	Pancreatic morphology QTL 2	3.2		pancreatic beta cell morphology trait (VT:0005217)	ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)	10	76748906	107211142	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70199100	107211142	Rat
2293698	Bss43	Bone structure and strength QTL 43	5.33	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	10	59209888	104209888	Rat
1576313	Pia25	Pristane induced arthritis QTL 25			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	96120911	104060283	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1576307	Cia28	Collagen induced arthritis QTL 28			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	96120911	104060283	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
2292438	Bp311	Blood pressure QTL 311			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	107211142	Rat
2312662	Slep8	Serum leptin concentration QTL 8		0.05	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	10	57134272	102134272	Rat
2292436	Bp310	Blood pressure QTL 310			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	94759759	107211142	Rat
1600367	Mcs15	Mammary carcinoma susceptibility QTL 15	4.5		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	85565469	103884409	Rat
631539	Oia6	Oil induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	97010147	104670812	Rat
631538	Oia5	Oil induced arthritis QTL 5			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87055121	107211142	Rat
61436	Cia5	Collagen induced arthritis QTL 5	4.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	91228102	104060283	Rat
1642980	Bp300	Blood pressure QTL 300			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68383129	107211142	Rat
2312668	Scl65	Serum cholesterol level QTL 65		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	57134272	102134272	Rat

D10Wox33

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RGSC_v3.4	10	106,574,981 - 106,575,106	UniSTS	RGSC3.4
Celera	10	100,266,045 - 100,266,170	UniSTS
Cytogenetic Map	10	q32.3	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	81	80	49	25	49	6	208	97	93	45	59	31


RefSeq Transcripts	NM_001416895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006247833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604193	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ605121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000034817 ⟹ ENSRNOP00000031300

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	101,669,224 - 101,697,656 (-)	Ensembl
Rnor_6.0 Ensembl	10	105,399,814 - 105,412,627 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115545 ⟹ ENSRNOP00000089618

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	101,669,224 - 101,697,656 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118329 ⟹ ENSRNOP00000093487

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	101,669,224 - 101,697,656 (-)	Ensembl

RefSeq Acc Id:

NM_001416895 ⟹ NP_001403824

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	102,168,103 - 102,196,497 (-)	NCBI
mRatBN7.2	10	101,669,240 - 101,697,643 (-)	NCBI


Protein RefSeqs	NP_001403824	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM06668	(Get FASTA)	NCBI Sequence Viewer
	EDM06669	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031300.5
	ENSRNOP00000089618.1
	ENSRNOP00000093487.1
	ENSRNOP00000111628

Ensembl Acc Id:

ENSRNOP00000031300 ⟸ ENSRNOT00000034817

Ensembl Acc Id:

ENSRNOP00000089618 ⟸ ENSRNOT00000115545

Ensembl Acc Id:

ENSRNOP00000093487 ⟸ ENSRNOT00000118329

RefSeq Acc Id:	NP_001403824 ⟸ NM_001416895
- UniProtKB:	A0A8I6AX39 (UniProtKB/TrEMBL)

Protein Domains

DUF4795

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZG97-F1-model_v2	AlphaFold	D3ZG97	1-584	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-22606	BioCyc
Ensembl Genes	ENSRNOG00000025254	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034817.7	UniProtKB/TrEMBL
	ENSRNOT00000115545.1	UniProtKB/TrEMBL
	ENSRNOT00000118329.1	UniProtKB/TrEMBL
	ENSRNOT00000169530	ENTREZGENE
InterPro	DUF4795	UniProtKB/TrEMBL
NCBI Gene	501747	ENTREZGENE
PANTHER	GLUTAMINE-RICH PROTEIN 2	UniProtKB/TrEMBL
	GLUTAMINE-RICH PROTEIN 2	UniProtKB/TrEMBL
Pfam	DUF4795	UniProtKB/TrEMBL
PhenoGen	Qrich2	PhenoGen
RatGTEx	ENSRNOG00000025254	RatGTEx
UniProt	A0A8I6AC52_RAT	UniProtKB/TrEMBL
	A0A8I6AX39	ENTREZGENE, UniProtKB/TrEMBL
	D3ZG97_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Qrich2	glutamine rich 2	RGD1562974_predicted	similar to hypothetical protein DKFZp434P0316 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1562974_predicted	similar to hypothetical protein DKFZp434P0316 (predicted)	LOC501747	similar to hypothetical protein DKFZp434P0316	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC501747	similar to hypothetical protein DKFZp434P0316			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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