Bcl2l14 (Bcl2-like 14) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Bcl2l14 (Bcl2-like 14) Rattus norvegicus
Analyze
Symbol: Bcl2l14
Name: Bcl2-like 14
RGD ID: 1562777
Description: Predicted to enable protein kinase binding activity. Predicted to be involved in apoptotic process and positive regulation of extrinsic apoptotic signaling pathway. Predicted to be located in cytosol. Orthologous to human BCL2L14 (BCL2 like 14); INTERACTS WITH 2,5-hexanedione; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: apoptosis facilitator Bcl-2-like protein 14; BCL2 like 14; bcl2-L-14; Bcl2-like 14 (apoptosis facilitator); LOC500348; similar to Apoptosis facilitator Bcl-2-like protein 14
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84168,948,919 - 168,989,450 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4168,948,946 - 168,990,079 (+)EnsemblGRCr8
mRatBN7.24167,217,561 - 167,258,723 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4167,219,871 - 167,258,086 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4173,511,031 - 173,551,506 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04169,294,099 - 169,334,579 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04167,919,705 - 167,960,117 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd4171,152,602 - 171,193,012 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive4168,809,396 - 168,849,801 (+)NCBILyon_Normotensive
Lyon_Hypertensive4169,305,302 - 169,345,705 (+)NCBILyon_Hypertensive
F344_StmMcwi4168,638,081 - 168,678,491 (+)NCBIF344_StmMcwi
Rnor_6.04168,139,964 - 168,183,726 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4168,142,271 - 168,183,096 (+)Ensemblrn6Rnor6.0
Rnor_5.04232,424,702 - 232,465,234 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44171,283,106 - 171,325,345 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4155,818,726 - 155,858,644 (+)NCBICelera
Cytogenetic Map4q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,5-hexanedione  (EXP)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calyculin A  (ISO)
carbendazim  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
clozapine  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dieldrin  (EXP)
entinostat  (ISO)
folic acid  (ISO)
furan  (EXP)
gardiquimod  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
levonorgestrel  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
protein kinase inhibitor  (ISO)
quercetin  (ISO)
sanguinarine  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
testosterone undecanoate  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
trametinib  (ISO)
trichloroethene  (EXP)
Triptolide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Expression mapping at 12p12-13 in advanced prostate carcinoma. Kibel AS, etal., Int J Cancer. 2004 May 1;109(5):668-72.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11054413   PMID:15489334   PMID:17280616  


Genomics

Comparative Map Data
Bcl2l14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84168,948,919 - 168,989,450 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4168,948,946 - 168,990,079 (+)EnsemblGRCr8
mRatBN7.24167,217,561 - 167,258,723 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4167,219,871 - 167,258,086 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4173,511,031 - 173,551,506 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04169,294,099 - 169,334,579 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04167,919,705 - 167,960,117 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd4171,152,602 - 171,193,012 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive4168,809,396 - 168,849,801 (+)NCBILyon_Normotensive
Lyon_Hypertensive4169,305,302 - 169,345,705 (+)NCBILyon_Hypertensive
F344_StmMcwi4168,638,081 - 168,678,491 (+)NCBIF344_StmMcwi
Rnor_6.04168,139,964 - 168,183,726 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4168,142,271 - 168,183,096 (+)Ensemblrn6Rnor6.0
Rnor_5.04232,424,702 - 232,465,234 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44171,283,106 - 171,325,345 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4155,818,726 - 155,858,644 (+)NCBICelera
Cytogenetic Map4q43NCBI
BCL2L14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381212,049,861 - 12,099,695 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1212,049,844 - 12,211,084 (+)Ensemblhg38GRCh38
GRCh371212,202,795 - 12,252,629 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361212,115,145 - 12,255,214 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1217,366,919 - 17,395,671 (+)NCBICelera
Cytogenetic Map12p13.2NCBI
HuRef1211,989,236 - 12,017,868 (+)NCBIHuRef
CHM1_11212,188,895 - 12,217,646 (+)NCBICHM1_1
T2T-CHM13v2.01211,918,992 - 11,968,813 (+)NCBIT2T-CHM13v2.0
Bcl2l14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396134,373,292 - 134,415,687 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6134,373,281 - 134,415,699 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm386134,396,329 - 134,438,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6134,396,318 - 134,438,736 (+)Ensemblmm10GRCm38
MGSCv376134,346,347 - 134,388,742 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366134,362,022 - 134,404,417 (+)NCBIMGSCv36mm8
Celera6137,330,165 - 137,373,292 (+)NCBICelera
Cytogenetic Map6G1NCBI
cM Map665.22NCBI
Bcl2l14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554139,055,126 - 9,069,007 (+)Ensembl
ChiLan1.0NW_0049554139,040,272 - 9,069,266 (+)NCBIChiLan1.0ChiLan1.0
BCL2L14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21017,514,827 - 17,565,265 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11217,511,583 - 17,561,702 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01212,072,021 - 12,122,015 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11212,442,890 - 12,492,777 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1212,444,839 - 12,492,777 (+)EnsemblpanPan2panpan1.1
BCL2L14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12734,179,481 - 34,216,374 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2734,180,064 - 34,200,095 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2712,230,703 - 12,267,188 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02734,486,222 - 34,523,138 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2734,486,809 - 34,506,857 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12734,378,545 - 34,414,890 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02734,328,874 - 34,365,285 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02711,960,732 - 11,997,624 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bcl2l14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494595,431,727 - 95,470,473 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365875,160,085 - 5,174,855 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365875,160,085 - 5,174,855 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL2L14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl560,332,451 - 60,357,897 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1560,334,813 - 60,357,935 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2563,690,607 - 63,713,914 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BCL2L14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11111,961,329 - 12,001,903 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1111,973,010 - 12,002,128 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606923,320,886 - 23,350,202 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl2l14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475225,763,749 - 25,800,040 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475225,762,860 - 25,799,990 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Bcl2l14
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1615,012,937 - 15,036,559 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Bcl2l14
219 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:165
Count of miRNA genes:125
Interacting mature miRNAs:138
Transcripts:ENSRNOT00000032229
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat

Markers in Region
BF417076  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24167,257,922 - 167,258,062 (+)MAPPERmRatBN7.2
Rnor_6.04168,182,926 - 168,183,065NCBIRnor6.0
Rnor_5.04232,465,065 - 232,465,204UniSTSRnor5.0
RGSC_v3.44171,325,181 - 171,325,320UniSTSRGSC3.4
Celera4155,858,480 - 155,858,619UniSTS
RH 3.4 Map41016.0UniSTS
Cytogenetic Map4q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 12 58 148 91 90 59 90 59 6 357 182 13 123 85 114 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000032229   ⟹   ENSRNOP00000029468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4168,948,946 - 168,990,079 (+)Ensembl
mRatBN7.2 Ensembl4167,219,871 - 167,258,086 (+)Ensembl
Rnor_6.0 Ensembl4168,142,271 - 168,183,096 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173534   ⟹   ENSRNOP00000104674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4168,948,946 - 168,990,079 (+)Ensembl
RefSeq Acc Id: NM_001024338   ⟹   NP_001019509
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84168,948,980 - 168,989,449 (+)NCBI
mRatBN7.24167,217,612 - 167,258,087 (+)NCBI
Dahl_SR_JrHsd4171,152,602 - 171,193,012 (+)NCBI
Lyon_Normotensive4168,809,396 - 168,849,801 (+)NCBI
Lyon_Hypertensive4169,305,302 - 169,345,705 (+)NCBI
F344_StmMcwi4168,638,081 - 168,678,491 (+)NCBI
Rnor_6.04168,140,008 - 168,183,090 (+)NCBI
Rnor_5.04232,424,702 - 232,465,234 (+)NCBI
RGSC_v3.44171,283,106 - 171,325,345 (+)RGD
Celera4155,818,726 - 155,858,644 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237533   ⟹   XP_006237595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84168,948,919 - 168,989,450 (+)NCBI
mRatBN7.24167,217,561 - 167,258,723 (+)NCBI
Rnor_6.04168,139,964 - 168,183,726 (+)NCBI
Rnor_5.04232,424,702 - 232,465,234 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237534   ⟹   XP_006237596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84168,965,960 - 168,989,450 (+)NCBI
mRatBN7.24167,234,714 - 167,258,723 (+)NCBI
Rnor_6.04168,159,646 - 168,183,726 (+)NCBI
Rnor_5.04232,424,702 - 232,465,234 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592836   ⟹   XP_017448325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84168,956,101 - 168,989,450 (+)NCBI
mRatBN7.24167,224,745 - 167,258,723 (+)NCBI
Rnor_6.04168,147,174 - 168,183,726 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039108221   ⟹   XP_038964149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84168,948,930 - 168,989,450 (+)NCBI
mRatBN7.24167,217,562 - 167,258,723 (+)NCBI
RefSeq Acc Id: NP_001019509   ⟸   NM_001024338
- UniProtKB: Q6AYK4 (UniProtKB/Swiss-Prot),   A6IMD0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237595   ⟸   XM_006237533
- Peptide Label: isoform X1
- UniProtKB: Q6AYK4 (UniProtKB/Swiss-Prot),   A6IMD0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237596   ⟸   XM_006237534
- Peptide Label: isoform X1
- UniProtKB: Q6AYK4 (UniProtKB/Swiss-Prot),   A6IMD0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448325   ⟸   XM_017592836
- Peptide Label: isoform X1
- UniProtKB: Q6AYK4 (UniProtKB/Swiss-Prot),   A6IMD0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029468   ⟸   ENSRNOT00000032229
RefSeq Acc Id: XP_038964149   ⟸   XM_039108221
- Peptide Label: isoform X1
- UniProtKB: Q6AYK4 (UniProtKB/Swiss-Prot),   A6IMD0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000104674   ⟸   ENSRNOT00000173534

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYK4-F1-model_v2 AlphaFold Q6AYK4 1-326 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562777 AgrOrtholog
BioCyc Gene G2FUF-42658 BioCyc
Ensembl Genes ENSRNOG00000028632 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000032229 ENTREZGENE
  ENSRNOT00000032229.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.437.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7113223 IMAGE-MGC_LOAD
InterPro Bcl2-like UniProtKB/Swiss-Prot
  Blc2-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:500348 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93927 IMAGE-MGC_LOAD
NCBI Gene 500348 ENTREZGENE
PANTHER PTHR14965:SF1 UniProtKB/Swiss-Prot
  SI:CH73-248E21.1 UniProtKB/Swiss-Prot
PhenoGen Bcl2l14 PhenoGen
PROSITE BCL2_FAMILY UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000028632 RatGTEx
Superfamily-SCOP SSF56854 UniProtKB/Swiss-Prot
UniProt A0ABK0LII0_RAT UniProtKB/TrEMBL
  A6IMD0 ENTREZGENE, UniProtKB/TrEMBL
  B2L14_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-04-05 Bcl2l14  Bcl2-like 14  BCL2l14  BCL2-like 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-04-05 BCL2l14  BCL2-like 14  Bcl2l14  BCL2 like 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-20 Bcl2l14  BCL2 like 14  Bcl2l14  Bcl2-like 14 (apoptosis facilitator)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Bcl2l14  Bcl2-like 14 (apoptosis facilitator)  LOC500348  similar to Apoptosis facilitator Bcl-2-like protein 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC500348  similar to Apoptosis facilitator Bcl-2-like protein 14      Symbol and Name status set to provisional 70820 PROVISIONAL