Zfp711 (zinc finger protein 711) - Rat Genome Database

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Gene: Zfp711 (zinc finger protein 711) Rattus norvegicus
Analyze
Symbol: Zfp711
Name: zinc finger protein 711
RGD ID: 1562768
Description: Predicted to enable chromatin insulator sequence binding activity and sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in chromosome. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 97. Orthologous to human ZNF711 (zinc finger protein 711); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; testosterone.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC302327; RGD1562768; similar to ZNF6 protein; Znf711
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X81,838,483 - 81,871,767 (+)NCBIGRCr8
mRatBN7.2X77,646,300 - 77,679,398 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX77,646,558 - 77,678,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX79,304,379 - 79,337,338 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X82,734,477 - 82,767,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X80,322,903 - 80,355,831 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X84,062,363 - 84,095,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX84,064,427 - 84,096,617 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X84,011,437 - 84,045,090 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X101,187,139 - 101,215,168 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX78,946,332 - 78,979,432 (+)NCBICelera
Cytogenetic MapXq31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IBA)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20346720   PMID:23376485  


Genomics

Comparative Map Data
Zfp711
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X81,838,483 - 81,871,767 (+)NCBIGRCr8
mRatBN7.2X77,646,300 - 77,679,398 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX77,646,558 - 77,678,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX79,304,379 - 79,337,338 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X82,734,477 - 82,767,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X80,322,903 - 80,355,831 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X84,062,363 - 84,095,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX84,064,427 - 84,096,617 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X84,011,437 - 84,045,090 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X101,187,139 - 101,215,168 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX78,946,332 - 78,979,432 (+)NCBICelera
Cytogenetic MapXq31NCBI
ZNF711
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X85,243,991 - 85,273,357 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX85,243,991 - 85,273,362 (+)EnsemblGRCh38hg38GRCh38
GRCh37X84,498,997 - 84,528,363 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X84,385,653 - 84,415,024 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X84,305,235 - 84,333,072NCBI
CeleraX84,738,361 - 84,767,732 (+)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX78,072,499 - 78,101,368 (+)NCBIHuRef
CHM1_1X84,392,701 - 84,421,999 (+)NCBICHM1_1
T2T-CHM13v2.0X83,672,840 - 83,701,879 (+)NCBIT2T-CHM13v2.0
Zfp711
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X111,510,259 - 111,544,767 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX111,510,223 - 111,544,767 (+)EnsemblGRCm39 Ensembl
GRCm38X112,600,526 - 112,635,070 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX112,600,526 - 112,635,070 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X109,714,135 - 109,748,671 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X108,717,470 - 108,743,017 (+)NCBIMGSCv36mm8
CeleraX99,225,536 - 99,256,329 (+)NCBICelera
Cytogenetic MapXE1NCBI
cM MapX48.76NCBI
Znf711
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555294,111,128 - 4,136,415 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555294,108,202 - 4,134,696 (+)NCBIChiLan1.0ChiLan1.0
ZNF711
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X84,721,086 - 84,750,712 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X84,724,693 - 84,754,319 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X74,314,161 - 74,343,246 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X84,424,414 - 84,453,640 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX84,424,414 - 84,453,640 (+)Ensemblpanpan1.1panPan2
ZNF711
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X66,203,972 - 66,229,171 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX66,203,463 - 66,227,641 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX56,961,170 - 56,986,414 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X67,535,617 - 67,560,856 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX67,535,680 - 67,560,852 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X65,183,316 - 65,208,559 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X66,820,121 - 66,845,363 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X66,412,311 - 66,437,559 (+)NCBIUU_Cfam_GSD_1.0
Znf711
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X59,679,312 - 59,706,282 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365475,999,739 - 6,026,769 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365475,999,792 - 6,026,719 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF711
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX68,475,636 - 68,499,321 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X68,475,512 - 68,499,329 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X78,275,335 - 78,322,084 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF711
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X74,093,028 - 74,121,805 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX74,094,789 - 74,122,024 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660676,715,412 - 6,744,125 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf711
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248523,138,699 - 3,159,501 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248523,137,206 - 3,163,124 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfp711
51 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:77
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000046364
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat

Markers in Region
WI-14596  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X77,679,410 - 77,679,539 (+)MAPPERmRatBN7.2
Rnor_6.0X84,095,901 - 84,096,029NCBIRnor6.0
Rnor_5.0X84,044,948 - 84,045,076UniSTSRnor5.0
RGSC_v3.4X101,216,542 - 101,216,670UniSTSRGSC3.4
CeleraX78,979,445 - 78,979,573UniSTS
Cytogenetic MapXq32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 46 10
Low 1 32 11 11 9 11 1 1 28 27 31 11 1
Below cutoff 2 10 41 25 10 25 6 6 8 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001401122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_002727619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_002730265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000046364   ⟹   ENSRNOP00000041511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX77,646,558 - 77,678,045 (+)Ensembl
Rnor_6.0 EnsemblX84,064,427 - 84,096,617 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095292   ⟹   ENSRNOP00000080686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX77,646,558 - 77,678,045 (+)Ensembl
RefSeq Acc Id: NM_001401122   ⟹   NP_001388051
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,838,682 - 81,871,618 (+)NCBI
mRatBN7.2X77,646,462 - 77,679,398 (+)NCBI
RefSeq Acc Id: XM_002730265   ⟹   XP_002730311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,838,502 - 81,871,767 (+)NCBI
mRatBN7.2X77,646,300 - 77,679,398 (+)NCBI
Rnor_6.0X84,062,363 - 84,095,888 (+)NCBI
Rnor_5.0X84,011,437 - 84,045,090 (+)NCBI
RGSC_v3.4X101,187,139 - 101,215,168 (+)RGD
Sequence:
RefSeq Acc Id: XM_017602345   ⟹   XP_017457834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,838,483 - 81,871,767 (+)NCBI
mRatBN7.2X77,646,300 - 77,679,398 (+)NCBI
Rnor_6.0X84,062,363 - 84,095,888 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039100220   ⟹   XP_038956148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,838,483 - 81,871,767 (+)NCBI
mRatBN7.2X77,646,300 - 77,679,398 (+)NCBI
RefSeq Acc Id: XM_063279891   ⟹   XP_063135961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X81,838,483 - 81,871,767 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_002730311   ⟸   XM_002730265
- Peptide Label: isoform X1
- UniProtKB: D3ZHB2 (UniProtKB/TrEMBL),   A6IVA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457834   ⟸   XM_017602345
- Peptide Label: isoform X1
- UniProtKB: D3ZHB2 (UniProtKB/TrEMBL),   A6IVA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000041511   ⟸   ENSRNOT00000046364
RefSeq Acc Id: XP_038956148   ⟸   XM_039100220
- Peptide Label: isoform X1
- UniProtKB: D3ZHB2 (UniProtKB/TrEMBL),   A6IVA2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000080686   ⟸   ENSRNOT00000095292
RefSeq Acc Id: NP_001388051   ⟸   NM_001401122
- UniProtKB: A0A8I5ZQU3 (UniProtKB/TrEMBL),   A6IVA2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135961   ⟸   XM_063279891
- Peptide Label: isoform X2
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHB2-F1-model_v2 AlphaFold D3ZHB2 1-805 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562768 AgrOrtholog
BioCyc Gene G2FUF-1831 BioCyc
Ensembl Genes ENSRNOG00000022391 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046364.5 UniProtKB/TrEMBL
  ENSRNOT00000095292 ENTREZGENE
  ENSRNOT00000095292.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Transcrp_activ_Zfx/Zfy-dom UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:302327 UniProtKB/TrEMBL
NCBI Gene 302327 ENTREZGENE
PANTHER FEZ FAMILY ZINC FINGER PROTEIN ERM UniProtKB/TrEMBL
  IP01201P-RELATED UniProtKB/TrEMBL
  ZGC:162958 PROTEIN-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 200 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
  Zfx_Zfy_act UniProtKB/TrEMBL
PhenoGen Zfp711 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022391 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A8I5ZQU3 ENTREZGENE, UniProtKB/TrEMBL
  A6IVA2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZHB2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-19 Zfp711  zinc finger protein 711  Znf711  zinc finger protein 711  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-07 Znf711  zinc finger protein 711  RGD1562768  similar to ZNF6 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1562768  similar to ZNF6 protein   RGD1562768_predicted  similar to ZNF6 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562768_predicted  similar to ZNF6 protein (predicted)  LOC302327  similar to ZNF6 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302327  similar to ZNF6 protein      Symbol and Name status set to provisional 70820 PROVISIONAL