Cidec (cell death-inducing DFFA-like effector c) - Rat Genome Database

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Gene: Cidec (cell death-inducing DFFA-like effector c) Rattus norvegicus
Analyze
Symbol: Cidec
Name: cell death-inducing DFFA-like effector c
RGD ID: 1562113
Description: Predicted to enable lipid transfer activity; molecular condensate scaffold activity; and phospholipid binding activity. Predicted to be involved in several processes, including execution phase of apoptosis; lipid droplet fusion; and negative regulation of lipid metabolic process. Predicted to be located in cytosol. Predicted to be active in lipid droplet. Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 5. Orthologous to human CIDEC (cell death inducing DFFA like effector c); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cell death activator CIDE-3; cell death-inducing DFFA-like effector protein C; fat-specific protein FSP27; lipid transferase CIDEC; LOC500292; similar to cell death-inducing DFFA-like effector c
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84148,124,924 - 148,137,806 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4148,124,925 - 148,137,806 (-)EnsemblGRCr8
mRatBN7.24146,569,288 - 146,582,173 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,569,289 - 146,582,173 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4151,953,209 - 151,966,039 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04147,734,054 - 147,746,884 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,355,674 - 146,368,501 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,377,482 - 145,390,497 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,377,431 - 145,390,497 (-)Ensemblrn6Rnor6.0
Rnor_5.04208,674,528 - 208,687,883 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44149,307,986 - 149,321,303 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4135,125,642 - 135,138,206 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-pantothenic acid  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17beta-estradiol  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-chloroethanol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-phenylbutyric acid  (ISO)
7,12-dimethyltetraphene  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (ISO)
amphetamine  (EXP)
arotinoid acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
biotin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CHIR 99021  (ISO)
chlordecone  (ISO)
choline  (ISO)
ciglitazone  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP)
colforsin daropate hydrochloride  (ISO)
cortisol  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutylstannane  (ISO)
diethyl malate  (ISO)
diethyl maleate  (EXP)
diquat  (ISO)
diuron  (EXP)
emodin  (ISO)
endosulfan  (EXP,ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
furan  (ISO)
genistein  (ISO)
graphene oxide  (ISO)
hexadecanoic acid  (ISO)
indinavir  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
KT 5720  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lamivudine  (ISO)
lipopolysaccharide  (ISO)
methyl methanesulfonate  (ISO)
metolachlor  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (EXP)
oleic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
Ptaquiloside  (ISO)
quercetin  (ISO)
quinoxyfen  (ISO)
rifaximin  (ISO)
saquinavir  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thyroxine  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP,ISO)
triflumizole  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
triticonazole  (EXP)
troglitazone  (ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
XAV939  (ISO)
XL147  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA,ISO)
endoplasmic reticulum  (IEA)
lipid droplet  (IBA,IEA,ISO,ISS)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:12429024   PMID:20049731   PMID:21996045   PMID:22752386   PMID:27716232   PMID:29078040   PMID:31205943   PMID:33655702  


Genomics

Comparative Map Data
Cidec
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84148,124,924 - 148,137,806 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4148,124,925 - 148,137,806 (-)EnsemblGRCr8
mRatBN7.24146,569,288 - 146,582,173 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,569,289 - 146,582,173 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4151,953,209 - 151,966,039 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04147,734,054 - 147,746,884 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,355,674 - 146,368,501 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,377,482 - 145,390,497 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,377,431 - 145,390,497 (-)Ensemblrn6Rnor6.0
Rnor_5.04208,674,528 - 208,687,883 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44149,307,986 - 149,321,303 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4135,125,642 - 135,138,206 (-)NCBICelera
Cytogenetic Map4q42NCBI
CIDEC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3839,866,710 - 9,880,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl39,866,710 - 9,880,256 (-)Ensemblhg38GRCh38
GRCh3739,908,394 - 9,921,937 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3639,883,398 - 9,895,740 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3439,883,398 - 9,895,740NCBI
Celera39,843,853 - 9,856,196 (-)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef39,844,688 - 9,858,278 (-)NCBIHuRef
CHM1_139,858,598 - 9,872,132 (-)NCBICHM1_1
T2T-CHM13v2.039,858,718 - 9,872,261 (-)NCBIT2T-CHM13v2.0
Cidec
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396113,401,595 - 113,412,721 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6113,401,595 - 113,412,721 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386113,424,634 - 113,435,760 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6113,424,634 - 113,435,760 (-)Ensemblmm10GRCm38
MGSCv376113,374,630 - 113,385,749 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366113,390,413 - 113,401,532 (-)NCBIMGSCv36mm8
Celera6115,251,600 - 115,262,724 (-)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.76NCBI
Cidec
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555611,363,907 - 1,376,144 (-)NCBIChiLan1.0ChiLan1.0
CIDEC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v229,871,509 - 9,895,113 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan139,876,268 - 9,900,349 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v039,811,995 - 9,836,069 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1310,048,161 - 10,174,570 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl310,048,554 - 10,173,107 (-)EnsemblpanPan2panpan1.1
CIDEC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1208,386,334 - 8,402,076 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl208,386,415 - 8,401,774 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha208,390,809 - 8,435,294 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0208,415,622 - 8,431,383 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl208,415,672 - 8,431,382 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1208,138,175 - 8,154,070 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0208,483,180 - 8,498,478 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0208,456,276 - 8,471,982 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cidec
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494215,586,703 - 15,597,550 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366023,313,208 - 3,322,604 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366023,312,146 - 3,323,009 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CIDEC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1366,141,839 - 66,149,703 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11366,141,836 - 66,149,801 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21373,216,901 - 73,224,864 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CIDEC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12245,895,455 - 45,917,236 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2245,895,249 - 45,910,658 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041120,646,801 - 120,668,336 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cidec
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247314,474,689 - 4,484,894 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247314,474,912 - 4,484,866 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cidec
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1633,103,865 - 33,115,637 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cidec
65 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:84
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000012136
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4121020385148834277Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 34 129 91 90 59 70 59 6 295 137 11 103 75 88 31 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000012136   ⟹   ENSRNOP00000012136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,124,925 - 148,137,806 (-)Ensembl
mRatBN7.2 Ensembl4146,569,289 - 146,582,173 (-)Ensembl
Rnor_6.0 Ensembl4145,377,483 - 145,390,497 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000091965   ⟹   ENSRNOP00000073293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,124,925 - 148,137,115 (-)Ensembl
mRatBN7.2 Ensembl4146,569,289 - 146,581,482 (-)Ensembl
Rnor_6.0 Ensembl4145,377,431 - 145,390,447 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103082   ⟹   ENSRNOP00000087929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,124,925 - 148,136,653 (-)Ensembl
mRatBN7.2 Ensembl4146,569,289 - 146,581,020 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107191   ⟹   ENSRNOP00000097104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,569,289 - 146,580,776 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118684   ⟹   ENSRNOP00000090307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,124,925 - 148,137,691 (-)Ensembl
mRatBN7.2 Ensembl4146,569,289 - 146,581,396 (-)Ensembl
RefSeq Acc Id: NM_001024333   ⟹   NP_001019504
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,124,924 - 148,137,115 (-)NCBI
mRatBN7.24146,569,288 - 146,581,482 (-)NCBI
Rnor_6.04145,377,482 - 145,389,806 (-)NCBI
Rnor_5.04208,674,528 - 208,687,883 (-)NCBI
RGSC_v3.44149,307,986 - 149,321,303 (-)RGD
Celera4135,125,642 - 135,137,515 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001244797   ⟹   NP_001231726
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,124,924 - 148,137,806 (-)NCBI
mRatBN7.24146,569,288 - 146,582,173 (-)NCBI
Rnor_6.04145,377,482 - 145,390,497 (-)NCBI
Rnor_5.04208,674,528 - 208,687,883 (-)NCBI
Celera4135,125,642 - 135,138,206 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001244798   ⟹   NP_001231727
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,124,924 - 148,137,806 (-)NCBI
mRatBN7.24146,569,288 - 146,582,173 (-)NCBI
Rnor_6.04145,377,482 - 145,390,497 (-)NCBI
Rnor_5.04208,674,528 - 208,687,883 (-)NCBI
Celera4135,125,642 - 135,138,206 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039108207   ⟹   XP_038964135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,124,924 - 148,135,476 (-)NCBI
mRatBN7.24146,569,288 - 146,579,851 (-)NCBI
RefSeq Acc Id: NP_001019504   ⟸   NM_001024333
- Peptide Label: isoform 1
- UniProtKB: A0A0G2K551 (UniProtKB/TrEMBL),   A0A8I6A975 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231727   ⟸   NM_001244798
- Peptide Label: isoform 2
- UniProtKB: Q5XI33 (UniProtKB/Swiss-Prot),   A0A8I6A975 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231726   ⟸   NM_001244797
- Peptide Label: isoform 2
- UniProtKB: Q5XI33 (UniProtKB/Swiss-Prot),   A0A8I6A975 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012136   ⟸   ENSRNOT00000012136
Ensembl Acc Id: ENSRNOP00000073293   ⟸   ENSRNOT00000091965
RefSeq Acc Id: XP_038964135   ⟸   XM_039108207
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000090307   ⟸   ENSRNOT00000118684
Ensembl Acc Id: ENSRNOP00000087929   ⟸   ENSRNOT00000103082
Ensembl Acc Id: ENSRNOP00000097104   ⟸   ENSRNOT00000107191
Protein Domains
CIDE-N

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XI33-F1-model_v2 AlphaFold Q5XI33 1-238 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693302
Promoter ID:EPDNEW_R3825
Type:initiation region
Name:Cidec_1
Description:cell death-inducing DFFA-like effector c
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3826  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04145,389,818 - 145,389,878EPDNEW
RGD ID:13693304
Promoter ID:EPDNEW_R3826
Type:single initiation site
Name:Cidec_2
Description:cell death-inducing DFFA-like effector c
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3825  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04145,390,505 - 145,390,565EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562113 AgrOrtholog
BioCyc Gene G2FUF-43383 BioCyc
Ensembl Genes ENSRNOG00000009153 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012136 ENTREZGENE
  ENSRNOT00000012136.7 UniProtKB/Swiss-Prot
  ENSRNOT00000091965 ENTREZGENE
  ENSRNOT00000118684 ENTREZGENE
Gene3D-CATH 3.10.20.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7126532 IMAGE-MGC_LOAD
InterPro CIDE-N_dom UniProtKB/Swiss-Prot
KEGG Report rno:500292 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95093 IMAGE-MGC_LOAD
NCBI Gene 500292 ENTREZGENE
PANTHER CELL DEATH ACTIVATOR CIDE UniProtKB/Swiss-Prot
  CELL DEATH ACTIVATOR CIDE-3 UniProtKB/Swiss-Prot
Pfam CIDE-N UniProtKB/Swiss-Prot
PhenoGen Cidec PhenoGen
PROSITE CIDE_N UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009153 RatGTEx
SMART CAD UniProtKB/Swiss-Prot
Superfamily-SCOP CAD & PB1 domains UniProtKB/Swiss-Prot
UniProt A0A0G2K551 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A975 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GGI9_RAT UniProtKB/TrEMBL
  CIDEC_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Cidec  cell death-inducing DFFA-like effector c  LOC500292  similar to cell death-inducing DFFA-like effector c  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC500292  similar to cell death-inducing DFFA-like effector c      Symbol and Name status set to provisional 70820 PROVISIONAL