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Gene: Ppp1r1c (protein phosphatase 1, regulatory (inhibitor) subunit 1C) Rattus norvegicus

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Symbol:

Ppp1r1c

Name:

protein phosphatase 1, regulatory (inhibitor) subunit 1C

RGD ID:

1562095

Description:

Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human PPP1R1C (protein phosphatase 1 regulatory inhibitor subunit 1C); INTERACTS WITH 1-naphthyl isothiocyanate; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC499818; protein phosphatase 1 regulatory subunit 1C; RGD1562095; similar to protein phosphatase 1, regulatory (inhibitor) subunit 1C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	85,023,621 - 85,126,609 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	85,023,621 - 85,131,413 (+)	Ensembl				GRCr8
mRatBN7.2	3	64,616,700 - 64,719,696 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	64,616,700 - 64,724,104 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	67,967,911 - 68,071,790 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	76,551,501 - 76,655,372 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	74,298,190 - 74,402,356 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	66,673,060 - 66,783,501 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	66,673,071 - 66,780,075 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	73,232,214 - 73,334,814 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	62,519,426 - 62,622,517 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	64,072,550 - 64,174,267 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dibromoethane (ISO)

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

calcitriol (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

dexamethasone (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

emodin (ISO)

epoxiconazole (ISO)

fenvalerate (EXP)

formaldehyde (ISO)

glycidol (ISO)

indometacin (ISO)

methylmercury chloride (ISO)

mifepristone (ISO)

N-methyl-4-phenylpyridinium (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

PCB138 (ISO)

pirinixic acid (ISO)

quinolin-8-ol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular signal transduction (IBA)

signal transduction (IEA)

Cellular Component

cytoplasm (IBA)

Molecular Function

protein binding (ISO)

protein phosphatase inhibitor activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Ppp1r1c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	85,023,621 - 85,126,609 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	85,023,621 - 85,131,413 (+)	Ensembl				GRCr8
mRatBN7.2	3	64,616,700 - 64,719,696 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	64,616,700 - 64,724,104 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	67,967,911 - 68,071,790 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	76,551,501 - 76,655,372 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	74,298,190 - 74,402,356 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	66,673,060 - 66,783,501 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	66,673,071 - 66,780,075 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	73,232,214 - 73,334,814 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	62,519,426 - 62,622,517 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	64,072,550 - 64,174,267 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

PPP1R1C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	181,954,480 - 182,131,385 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	181,954,241 - 182,131,398 (+)	Ensembl			hg38	GRCh38
GRCh37	2	182,819,207 - 182,996,112 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	182,558,796 - 182,690,664 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	2	176,446,274 - 176,578,147 (+)	NCBI		Celera
Cytogenetic Map	2	q31.3-q32.1	NCBI
HuRef	2	174,674,996 - 174,852,128 (+)	NCBI		HuRef
CHM1_1	2	182,824,856 - 183,002,048 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	182,444,266 - 182,620,440 (+)	NCBI		T2T-CHM13v2.0

Ppp1r1c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	79,538,124 - 79,648,890 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	79,538,124 - 79,648,840 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	79,707,780 - 79,818,546 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	79,707,780 - 79,818,496 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	79,547,937 - 79,650,470 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	79,508,619 - 79,611,152 (+)	NCBI		MGSCv36	mm8
Celera	2	81,367,076 - 81,470,446 (+)	NCBI		Celera
Cytogenetic Map	2	C3	NCBI
cM Map	2	47.58	NCBI

Ppp1r1c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	15,214,761 - 15,340,568 (-)	Ensembl
ChiLan1.0	NW_004955403	15,219,140 - 15,340,467 (-)	NCBI	ChiLan1.0	ChiLan1.0

PPP1R1C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	84,626,112 - 84,771,246 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	84,648,989 - 84,786,219 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	69,247,701 - 69,407,444 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	187,057,091 - 187,206,722 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	187,057,091 - 187,206,722 (+)	Ensembl			panPan2	panpan1.1

PPP1R1C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	25,125,710 - 25,245,106 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	25,126,079 - 25,236,498 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	25,083,515 - 25,201,641 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	25,286,373 - 25,404,649 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	25,286,569 - 25,495,809 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	25,413,597 - 25,531,386 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	25,342,537 - 25,460,984 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	25,479,067 - 25,597,174 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ppp1r1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	142,124,513 - 142,249,462 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936509	10,678,363 - 10,803,508 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936509	10,678,397 - 10,801,382 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPP1R1C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	87,466,718 - 87,604,041 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	87,465,073 - 87,603,215 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PPP1R1C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	67,522,323 - 67,653,489 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	67,522,673 - 67,665,428 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	131,916,243 - 132,053,095 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppp1r1c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624844	3,763,706 - 3,887,440 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624844	3,763,755 - 3,882,472 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ppp1r1c
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	56,927,703 - 57,022,485 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ppp1r1c
885 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	277
Count of miRNA genes:	169
Interacting mature miRNAs:	203
Transcripts:	ENSRNOT00000034769
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	51490129	111359995	Rat
1358293	Bw38	Body weight QTL 38	6	0.0000031	body mass (VT:0001259)	body weight (CMO:0000012)	3	74364268	119364268	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	73592611	110333156	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	59863663	87321459	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	136118980	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	53651826	98651826	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	48876619	93876619	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	48876619	93876619	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	35403199	97383526	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
631832	Sach1	Saccharin preference QTL 1	2.7	0.02	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	3	47904172	92904172	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	59863663	87321459	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	85062224	136118980	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	51092561	96092561	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	85062224	136118980	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	81425008	141509147	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	48657744	93657744	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	70845569	136091483	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	58925062	103925062	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	70311536	115311536	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	81541464	126563126	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	48657744	93657744	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	50766145	95766145	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	51092561	96092561	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	50766145	95766145	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	36721849	110333156	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	48657744	93657744	Rat
1582249	Bw77	Body weight QTL 77	3.2	0.0025	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	85062403	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	42158111	124558371	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	48657744	93657744	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	48657744	93657744	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	42158111	124558371	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat

Markers in Region

D3Rat37

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	85,062,224 - 85,062,403 (+)	Marker Load Pipeline
mRatBN7.2	3	64,655,305 - 64,655,484 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	66,711,607 - 66,711,785	NCBI	Rnor6.0
Rnor_5.0	3	73,270,750 - 73,270,928	UniSTS	Rnor5.0
RGSC_v3.4	3	62,558,027 - 62,558,206	RGD	RGSC3.4
RGSC_v3.4	3	62,558,028 - 62,558,206	UniSTS	RGSC3.4
RGSC_v3.1	3	62,454,399 - 62,454,578	RGD
SHRSP x BN Map	3	40.5698	UniSTS
SHRSP x BN Map	3	40.5698	RGD
Cytogenetic Map	3	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
13	12	20	113	45	45	17	23	17	6	145	72	11	96	35	65	28	10	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109200	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000034769 ⟹ ENSRNOP00000035714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	85,023,621 - 85,126,609 (+)	Ensembl
mRatBN7.2 Ensembl	3	64,616,700 - 64,719,696 (+)	Ensembl
Rnor_6.0 Ensembl	3	66,673,071 - 66,775,671 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081338 ⟹ ENSRNOP00000070654

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	85,023,621 - 85,131,413 (+)	Ensembl
mRatBN7.2 Ensembl	3	64,616,700 - 64,724,104 (+)	Ensembl
Rnor_6.0 Ensembl	3	66,673,246 - 66,780,075 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104977 ⟹ ENSRNOP00000077764

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	85,023,621 - 85,124,313 (+)	Ensembl
mRatBN7.2 Ensembl	3	64,616,700 - 64,717,400 (+)	Ensembl

RefSeq Acc Id:

NM_001109200 ⟹ NP_001102670

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	85,023,621 - 85,126,609 (+)	NCBI
mRatBN7.2	3	64,616,700 - 64,719,696 (+)	NCBI
Rnor_6.0	3	66,673,071 - 66,775,671 (+)	NCBI
Rnor_5.0	3	73,232,214 - 73,334,814 (+)	NCBI
RGSC_v3.4	3	62,519,426 - 62,622,517 (+)	RGD
Celera	3	64,072,550 - 64,174,267 (+)	RGD

Sequence:

show sequence

GCAGCCGGCTAGTAATGTACAGTGGATAGAGCCTTTCTTTTAAATCCCAGGGCAGCAGGTCCTT
CAGGGCTAGCATTGCAATCTCAATTAGCCCCTGAGTGAAAGCTTGGCATGTGTATTAGTGAGCA
GAGACACAATTAGCTTATTCTTCCTTTCCGTGTTGTGTTGAGAGGAGCCAAAGGGTTGGTGGTG
GATCAGGAAAGCCAGGCATCACAGGATTTTGAAGAACAGAGTTGCTCAGACCTCGACATCTTCT
CTTGGTCACGCTGGAATTACAGAGATTTATTACAAAGCGCCGTGTGGGGCTTGGTGAAGGGTGT
CTCCGGAGACGCTTCGGACAGCAATCGAGCTCTGTCTTTTTGAGTGCTTCACCACTCTGTCTTA
GACTCATCATTAGCATGGAGCCCAACAGCCCCAAAAAGATACAATTTGCTGTGCCTTTATTCCA
GAGCCAGATCGCTCCAGAGGCAGCAGAGCAGATCAGGAAAAGAAGACCTACACCAGCATCCCTT
GTGATTCTCAATGAGCATAACCCCCCAGAAATTGATGAGAAGAGGGTGACCAACACACAAGAAT
CCCAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACGCCACCGGCTATGAAAGGAGT
TAAGCACCTGAAAGGCCAGAATGGATCGGCATTCCCGGAAGAAGAAGAAAGCGCAAGTGAAAGA
GAAGAAAAGTGGAACCATTAATTCCCCATCTGTAGCAAGAGGGCTTCTTGGAAGTGACTGGACG
GTTGACTCTTCTGAATATCCAATGGTACTCCAAAGTTCTGCCTCCAGCATCCTCTTCCGTCTCA
GCTCCCACCCTCTCAGCAGTGCGGTCCTCATGGAAGCCTCCTTGACTGAACTGTGAAACCGAGT
GCAGATCATCATTGTGTACCACTTGCAGCAAAGAATAGCACTTACTCTACCGCGATTTTTCTTT
TAAACTACTCAAACCTAGGAATCTGCTACTATGTGAATGTTCTCACTTTGATACTGCCAAAAGC
TTAACTCCTCCTGGCCTATGGTATGATTTACATTCTAAGGTCAAATGTAGAGAACATTACTCTA
AAAGTACAAAATAAATACCAAATGTGCTTGGGACGAGTGTGAGTGGGGATTAATGGAAGAGGAA
TGTTTACGGAAGCTTTTAATAACCGCATTTAGCATGCTTCTGTGTCTAGATCAAACCAGAGTTT
ACTTCAAGAAGACAACGATGTCAGTTGTCTTGATTCAAAACACCACATCAGATATGAAATGATT
TTCCTCCAACAGTGCATTAACAGCTACTTAAAGAAACAAATGTCTCTTTATTTTCTGAGCCGTC
CAATGTAGGCTCCTCAGCACCATCTAATCATTGAAAAGGAAATGCTAAATTTATAATAAAACAT
GGTAAATCTCTTCTGCTTTCTCTTTTTTCAACTCTTTAAAATTAAGCCATCTATAATGTATCTA
TAATGTATTTTGTTTGTCTGGGTTAGTCTGTTTTCTGTTGTTTCTTTTTGTTTTCTTGGTGCTA
GAGAATGAACCCAGGGCTTTGAACATGTACATATTCCTCTAGACTCTGTCCTCAGTCTTACTGC
AGTTTAATATATTCCGAGTGTTTTATTATTCTTCTCTGTGAGAGAATAAATACTGTCTTATTAA
TTCAGCCATAGACTCACCTATTAATTCGACGACTGCTTTTTGTGGAGTTTTAAAAAATCACTGT
AACTTTGAAATTAGTGTTACATCATTTCATCTTTCCCTTTCCTCTCAGCAAATCCTTCTACATA
CCACCCCTCAGCCCTTTTCAAGTTTGTTGCCTTTCTTTTCATTAATTGTTGCTAATTTTAATTA
TTCATGGTATATGAATGCACAATTTAGTGGGGATAGGTAATTTTGCTTCTACATTGGTTTTTAA
TGAGATTGAAATGTTTCATGAATATGAGGGAAAATCCATTGAAAACCATTAAAGCAAGAGGCTG
GTTATATATGTCAGTAGGTAAGAACACCTGTTGCCAAGGATAAGCTTAGTAGAAACCTACATGA
CAGGGGGAGAGAACCAATTGTCTCTCACTTCCGGAGAGGCATTGTCCTCTCACTTTTACCACAC
ACCTTGGTATGTGGGACACACACACACACACACACACACACACGCACACACACTAAATAATCAT
AAAAAAATTAAGAGAACATTAAGAACGGGAGAAAATAATAAAATGTGAAATTTACTATAAATCT
TAAATAAGATTGTTTTTAATTTGAAATTTTATAATGTGCTGATTAAGATATTATTGCATATTAT
TCCCCAGTGTCCATCCTGTCCTCTGCTTTCCTCTTCCTCTTCCTCCTCTTATCTTTCTCTCTTC
TCTCCATGTTGTCCTTGCTAAATCAATAAACCTTTAGAGTTTATTGCCACCTGCTATGGAGTAT
TTTTCTTCCCAAGTTCCTCTCTACTGAAAACATCATTAAGGTTGTATTTCTTGTAAATGCTTTT
GGGTTTTTTGTTTCCAGAACATTCCTGACATCCTCTGAGAGGGTTAGAGACTCGCTGGGGGGCA
CTAAGAGAAACAATAGCCACCTTTCCCCCTTTTCTTGAATACGGACTTTTATAAGTGCACCCCT
CCCACACCCCAGGCAAACAGGAGGAATCTGAAGCTCTCTCTGACATTGTGTGATCCTCTGAGGA
CAGGAGCAGCCTGACTTCTAAGCTTCTTTCTTTTGCTCTCTGTTGTTAATGGTATCAAACCATA
AGGTGCACATTTTCCTTGTGGAAGGTTGTTTCTTCCATCCCTTTGTTCACTCTCAAAACAAACC
AATTACAGTTTAAAGCTTACGTTTTGCTTGGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102670	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL79268	(Get FASTA)	NCBI Sequence Viewer
	EDL79269	(Get FASTA)	NCBI Sequence Viewer
	EDL79270	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000035714
	ENSRNOP00000035714.3
	ENSRNOP00000070654.1
	ENSRNOP00000077764.1

RefSeq Acc Id:	NP_001102670 ⟸ NM_001109200
- UniProtKB:	D3ZSW2 (UniProtKB/TrEMBL), A6HML7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPNSPKKIQFAVPLFQSQIAPEAAEQIRKRRPTPASLVILNEHNPPEIDEKRVTNTQESQNAS PKQRKQSVYTPPAMKGVKHLKGQNGSAFPEEEESASEREEKWNH hide sequence

Ensembl Acc Id:

ENSRNOP00000070654 ⟸ ENSRNOT00000081338

Ensembl Acc Id:

ENSRNOP00000035714 ⟸ ENSRNOT00000034769

Ensembl Acc Id:

ENSRNOP00000077764 ⟸ ENSRNOT00000104977

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZSW2-F1-model_v2	AlphaFold	D3ZSW2	1-108	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1562095	AgrOrtholog
BioCyc Gene	G2FUF-49230	BioCyc
Ensembl Genes	ENSRNOG00000024990	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034769	ENTREZGENE
	ENSRNOT00000034769.6	UniProtKB/TrEMBL
	ENSRNOT00000081338.3	UniProtKB/TrEMBL
	ENSRNOT00000104977.2	UniProtKB/TrEMBL
InterPro	PPI_1DARPP-32	UniProtKB/TrEMBL
KEGG Report	rno:499818	UniProtKB/TrEMBL
NCBI Gene	499818	ENTREZGENE
PANTHER	PPI_1DARPP-32	UniProtKB/TrEMBL
	PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1C	UniProtKB/TrEMBL
Pfam	DARPP-32	UniProtKB/TrEMBL
PhenoGen	Ppp1r1c	PhenoGen
RatGTEx	ENSRNOG00000024990	RatGTEx
UniProt	A0A0G2JYH2_RAT	UniProtKB/TrEMBL
	A0A8I5ZJK6_RAT	UniProtKB/TrEMBL
	A6HML7	ENTREZGENE, UniProtKB/TrEMBL
	D3ZSW2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-18	Ppp1r1c	protein phosphatase 1, regulatory (inhibitor) subunit 1C	RGD1562095_predicted	similar to protein phosphatase 1, regulatory (inhibitor) subunit 1C (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1562095_predicted	similar to protein phosphatase 1, regulatory (inhibitor) subunit 1C (predicted)	LOC499818	similar to protein phosphatase 1, regulatory (inhibitor) subunit 1C	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC499818	similar to protein phosphatase 1, regulatory (inhibitor) subunit 1C			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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